Q62682

PR
Gene name
Cntn3
Protein name
Contactin-3
Names
Brain-derived immunoglobulin superfamily protein 1, BIG-1
Species
Rattus norvegicus (Rat)
KEGG Pathway
rno:54279
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

958-1028 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q62682

Entry ID Method Resolution Chain Position Source
AF-Q62682-F1 Predicted AlphaFoldDB

1 variants for Q62682

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3320358154 18 A>E No EVA

No associated diseases with Q62682

24 regional properties for Q62682

Type Name Position InterPro Accession
domain Immunoglobulin subtype 2 41 - 107 IPR003598-1
domain Immunoglobulin subtype 2 135 - 203 IPR003598-2
domain Immunoglobulin subtype 2 240 - 304 IPR003598-3
domain Immunoglobulin subtype 2 330 - 393 IPR003598-4
domain Immunoglobulin subtype 2 422 - 486 IPR003598-5
domain Immunoglobulin subtype 2 512 - 584 IPR003598-6
domain Immunoglobulin subtype 35 - 119 IPR003599-1
domain Immunoglobulin subtype 129 - 217 IPR003599-2
domain Immunoglobulin subtype 234 - 315 IPR003599-3
domain Immunoglobulin subtype 324 - 404 IPR003599-4
domain Immunoglobulin subtype 416 - 497 IPR003599-5
domain Immunoglobulin subtype 506 - 595 IPR003599-6
domain Fibronectin type III 598 - 698 IPR003961-1
domain Fibronectin type III 701 - 800 IPR003961-2
domain Fibronectin type III 803 - 901 IPR003961-3
domain Fibronectin type III 902 - 998 IPR003961-4
domain Immunoglobulin-like domain 26 - 117 IPR007110-1
domain Immunoglobulin-like domain 122 - 208 IPR007110-2
domain Immunoglobulin-like domain 227 - 313 IPR007110-3
domain Immunoglobulin-like domain 318 - 402 IPR007110-4
domain Immunoglobulin-like domain 408 - 497 IPR007110-5
domain Immunoglobulin-like domain 499 - 593 IPR007110-6
domain Immunoglobulin I-set 320 - 403 IPR013098-1
domain Immunoglobulin I-set 409 - 496 IPR013098-2

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane; Lipid-anchor, GPI-anchor
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
anchored component of plasma membrane The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
neuron projection A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
cell-cell adhesion The attachment of one cell to another cell via adhesion molecules.
nervous system development The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.

7 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P32004 L1CAM Neural cell adhesion molecule L1 Homo sapiens (Human) PR
Q810U3 Nfasc Neurofascin Mus musculus (Mouse) PR
P11627 L1cam Neural cell adhesion molecule L1 Mus musculus (Mouse) PR
Q05695 L1cam Neural cell adhesion molecule L1 Rattus norvegicus (Rat) PR
Q62845 Cntn4 Contactin-4 Rattus norvegicus (Rat) PR
P0C5H6 Igsf9 Protein turtle homolog A Rattus norvegicus (Rat) PR
P13596 Ncam1 Neural cell adhesion molecule 1 Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MMLSWKQLIL LSFIGCLAGE LLLQGPVFVK EPSNSIFPVG SEDKKITLNC EARGNPSPHY
70 80 90 100 110 120
RWQLNGSDID TSLDHRYKLN GGNLIVINPN RNWDTGSYQC FATNSLGTIV SREAKLQFAY
130 140 150 160 170 180
LENFKSRMRS RVSVREGQGV VLLCGPPPHS GELSYAWVFN EYPSFVEEDS RRFVSQETGH
190 200 210 220 230 240
LYIAKVEPSD VGNYTCVVTS TVTNARVLGS PTPLVLRSDG VMGEYEPKIE LQFPETLPAA
250 260 270 280 290 300
KGSTVKLECF ALGNPVPQIN WRRSDGMPFP TKIKLRKFNG VLEIPNFQQE DTGSYECIAE
310 320 330 340 350 360
NSRGKNVARG RLTYYAKPYW VQLLKDVETA VEDSLYWECR ASGKPKPSYR WLKNGDALVL
370 380 390 400 410 420
EERIQIENGA LTIANLNVSD SGMFQCIAEN KHGLIYSSAE LKVLASAPDF SRNPMKKMIQ
430 440 450 460 470 480
VQVGSLVILD CKPSASPRAL SFWKKGDTVV REQARISLLN DGGLKIMNVT KADAGIYTCI
490 500 510 520 530 540
AENQFGKANG TTQLVVTEPT RIILAPSNMD VAVGESIILP CQVQHDPLLD IMFAWYFNGT
550 560 570 580 590 600
LTDFKKDGSH FEKVGGSSSG DLMIRNIQLK HSGKYVCMVQ TGVDSVSSAA ELIVRGSPGP
610 620 630 640 650 660
PENVKVDEIT DTTAQLSWTE GTDSHSPVIS YAVQARTPFS VGWQNVRTVP EAIDGKTRTA
670 680 690 700 710 720
TVVELNPWVE YEFRVVASNK IGGGEPSLPS EKVRTEEAAP EVAPSEVSGG GGSRSELVIT
730 740 750 760 770 780
WDPVPEELQN GGGFGYVVAF RPLGVTTWIQ TVVTSPDNPR YVFRNESIVP FSPYEVKVGV
790 800 810 820 830 840
YNNKGEGPFS PVTTVFSAEE EPTVAPSHIS AHSLSSSEIE VSWNTIPWKS SNGRLLGYEV
850 860 870 880 890 900
RYWNNGGEEE SSSKVKVAGN QTSAVLRGLK SNLAYYTAVR AYNTAGAGPF SATVNATTKK
910 920 930 940 950 960
TPPSQPPGNV VWNATDTKVL LNWEQVKALE NESEVTGYKV FYRTSSQNNV QVLNTNKTSA
970 980 990 1000 1010 1020
ELLLPIKEDY IIEVKATTDG GDGTSSEQIR IPRITSMDAR GSTSAISDIH PVSGYISVLL
FFIVNALW