Q05A13
Gene name |
Sdr16c6 |
Protein name |
Short-chain dehydrogenase/reductase family 16C member 6 |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:242286 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q05A13
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q05A13-F1 | Predicted | AlphaFoldDB |
19 variants for Q05A13
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs27703387 | 3 | S>P | No | EVA | |
| rs1132911468 | 6 | D>Y | No | EVA | |
| rs3388660703 | 11 | F>L | No | EVA | |
| rs3388666856 | 18 | F>L | No | EVA | |
| rs3388668317 | 24 | F>L | No | EVA | |
| rs3388671062 | 29 | K>* | No | EVA | |
| rs3388672361 | 34 | V>I | No | EVA | |
| rs3393649829 | 47 | G>E | No | EVA | |
| rs3388651277 | 82 | Q>P | No | EVA | |
| rs3388671766 | 83 | K>R | No | EVA | |
| rs3388666395 | 86 | V>A | No | EVA | |
| rs1132444461 | 88 | V>F | No | EVA | |
| rs3388675155 | 118 | L>R | No | EVA | |
| rs3388669613 | 129 | S>L | No | EVA | |
| rs3393665081 | 159 | A>T | No | EVA | |
| rs218523303 | 187 | S>C | No | EVA | |
| rs255266099 | 262 | I>F | No | EVA | |
| rs3388671064 | 287 | E>* | No | EVA | |
| rs3388668277 | 316 | Q>H | No | EVA |
No associated diseases with Q05A13
No regional properties for Q05A13
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q05A13 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| lipid droplet | An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
8 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q8HZT6 | RDH10 | Retinol dehydrogenase 10 | Bos taurus (Bovine) | PR |
| Q8IZV5 | RDH10 | Retinol dehydrogenase 10 | Homo sapiens (Human) | PR |
| Q8VCH7 | Rdh10 | Retinol dehydrogenase 10 | Mus musculus (Mouse) | PR |
| Q8VCR2 | Hsd17b13 | 17-beta-hydroxysteroid dehydrogenase 13 | Mus musculus (Mouse) | PR |
| Q80ZF7 | Rdh10 | Retinol dehydrogenase 10 | Rattus norvegicus (Rat) | PR |
| Q5XGF7 | rdh10 | Retinol dehydrogenase 10 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| A1L1W4 | rdh10a | Retinol dehydrogenase 10-A | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q7T2D1 | rdh10b | Retinol dehydrogenase 10-B | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNSVADTAIF | FGKFLYYFLE | SLVFKVIPKR | KKDVSGEIVL | ITGAGSGLGR | LLAIHFASHG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ATLVLWDINQ | EGNMETCRLV | KQKGDVKVFA | YKCDCSSRIE | VYRVADQVKE | EVGDVTILIN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NAGVVTGKSF | LNTPDHLVEK | SFLVNAISHF | WTCKAFLPAM | VKANHGHLVC | ISSIAGLVGI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NGLSDYSSSK | FAAFGFAESL | FLELTMIMKT | KVKSTIVCPY | FIKTGMFEGC | TTKYPLLLPL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LEQEYVAQKI | FNAILEEQVY | LIIPKFAYVA | LFLKQIISPK | MMIALGEYLG | VDTCMTSFTG |
| 310 | |||||
| RVKAEELQME | TKRKEQ |