P46990
Gene name |
RPL17B |
Protein name |
60S ribosomal protein L17-B |
Names |
L20, Large ribosomal subunit protein uL22-B, YL17 |
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YJL177W |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P46990
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P46990-F1 | Predicted | AlphaFoldDB |
No variants for P46990
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P46990 | |||||
No associated diseases with P46990
1 regional properties for P46990
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Ribosomal protein L22/L17, conserved site | 126 - 150 | IPR018260 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| cytosolic large ribosomal subunit | The large subunit of a ribosome located in the cytosol. |
| preribosome, large subunit precursor | A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| structural constituent of ribosome | The action of a molecule that contributes to the structural integrity of the ribosome. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | Endonucleolytic cleavage within ITS2 between the 5.8S rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. |
| cytoplasmic translation | The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein. |
8 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P05740 | RPL17A | 60S ribosomal protein L17-A | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q3T025 | RPL17 | 60S ribosomal protein L17 | Bos taurus (Bovine) | PR |
| Q5XTY7 | RPL17 | 60S ribosomal protein L17 | Felis catus (Cat) (Felis silvestris catus) | PR |
| Q9W3W8 | RpL17 | 60S ribosomal protein L17 | Drosophila melanogaster (Fruit fly) | PR |
| P18621 | RPL17 | 60S ribosomal protein L17 | Homo sapiens (Human) | PR |
| P24049 | Rpl17 | 60S ribosomal protein L17 | Rattus norvegicus (Rat) | PR |
| Q93VI3 | RPL17A | 60S ribosomal protein L17-1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P51413 | RPL17B | 60S ribosomal protein L17-2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MARYGATSTN | PAKSASARGS | YLRVSFKNTR | ETAQAINGWE | LTKAQKYLDQ | VLDHQRAIPF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RRFNSSIGRT | AQGKEFGVTK | ARWPAKSVKF | VQGLLQNAAA | NAEAKGLDAT | KLYVSHIQVN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QAPKQRRRTY | RAHGRINKYE | SSPSHIELVV | TEKEEAVAKA | AEKKVVRLTS | RQRGRIAAQK |
| RISA |