Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P34307

Entry ID Method Resolution Chain Position Source
AF-P34307-F1 Predicted AlphaFoldDB

No variants for P34307

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P34307

No associated diseases with P34307

1 regional properties for P34307

Type Name Position InterPro Accession
domain Transcription factor CBF/NF-Y/archaeal histone domain 10 - 74 IPR003958

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
mRNA binding Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.

3 GO annotations of biological process

Name Definition
regulation of gene expression Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).
regulation of mRNA splicing, via spliceosome Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism.
regulation of transcription by RNA polymerase II Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.

7 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P81021 HDLBP Vigilin Gallus gallus (Chicken) PR
Q24009 BicC Protein bicaudal C Drosophila melanogaster (Fruit fly) PR
Q00341 HDLBP Vigilin Homo sapiens (Human) PR
Q15365 PCBP1 Poly(rC)-binding protein 1 Homo sapiens (Human) PR
Q8VDJ3 Hdlbp Vigilin Mus musculus (Mouse) PR
P60335 Pcbp1 Poly(rC)-binding protein 1 Mus musculus (Mouse) PR
Q9Z1A6 Hdlbp Vigilin Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MAKTKDKSIF VSSVDSDSDI EEIIMPPKPP VEVIQLDDSD DECQDICKPI YNKKVHKDPI
70 80 90 100 110 120
VRVSYRQRIP ESYFPGISTS LINVQREHNN RSKYDTWGSN SCSEPRISIS NIERLEKPSY
130 140 150 160 170 180
HEARRVPVFE RLERSREISN GRNNQNPIRF NHKFVPPINR QTPLFNNQQL LVNVPFNEHH
190 200 210 220 230 240
PTFLEPRPFY RSNVNEYNAG GLNRGSFRKM GRLNMEIVRD NDDFEEHFLA PNFPAKSASI
250 260 270 280 290 300
DRRVDDSLSS NSYLRSGMIM ASSERLEDPR FSGRLPVFAR QINNQEINND NFYQNSICYN
310 320 330 340 350 360
HNNYPSNLES RVSFPFEARH HDADGLNRGR YQVMEHVNMG IMRNSEDFED YDITQTDQDN
370 380 390 400 410 420
HFYNDKDSGK HHRHRHRSKN NKKHKKHYDR NESGNSSECR EEDDYEISNP SEKRHERKKR
430 440 450 460 470 480
QRSSHRKESA CVDEDNYILD EDRFYQQESD EYHNSLEMER EYEHGMDVGV KKEHSYKCDD
490 500 510 520 530 540
IARNARKRAR LTDDDMARRE ELFKEWSYSK EIVDGVTQLF GGPPRESERH QKKQKELVFE
550 560 570 580 590 600
ADRTAMHALS IRSGALVKAR LLEIHYATGC HLIFLEEVKR GGYTYVELKG DPEHIKNAQK
610 620 630 640 650 660
MIDDMVIDEH YIHDGRESIV YFYNAPHELR NTRGFDLNCR SIEKYCGIII EKMREVFGIG
670 680 690 700 710 720
GYVSTAPLKL TGSVNSIHMA RETMQSKTKR FLDEEKFKET VEHCTPISFY RKIIGRCGEN
730 740 750 760 770 780
LKTIEKVTRT AIVFKRSFDN NEACFSIRGR TDNIKQAIEK IEEITHENQP ADDDPGIFQV
790 800 810 820 830 840
RVPENMVARL IGRHGVEINR IRSESKAKCY LNAIRGNLDD KFMVCSGGVE EAAYAAYLTK
850 860 870 880
VKIGIIDPKV IQFNSDDFNN LSKVKPMEDP RLVMLKKRYA ERKECK