Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P81021
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P81021-F1 | Predicted | AlphaFoldDB |
No variants for P81021
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P81021 | |||||
No associated diseases with P81021
28 regional properties for P81021
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | K Homology domain | 148 - 216 | IPR004087-1 |
| domain | K Homology domain | 220 - 288 | IPR004087-2 |
| domain | K Homology domain | 293 - 361 | IPR004087-3 |
| domain | K Homology domain | 362 - 428 | IPR004087-4 |
| domain | K Homology domain | 433 - 501 | IPR004087-5 |
| domain | K Homology domain | 505 - 574 | IPR004087-6 |
| domain | K Homology domain | 579 - 648 | IPR004087-7 |
| domain | K Homology domain | 652 - 725 | IPR004087-8 |
| domain | K Homology domain | 726 - 795 | IPR004087-9 |
| domain | K Homology domain | 799 - 869 | IPR004087-10 |
| domain | K Homology domain | 873 - 973 | IPR004087-11 |
| domain | K Homology domain | 974 - 1041 | IPR004087-12 |
| domain | K Homology domain | 1053 - 1124 | IPR004087-13 |
| domain | K Homology domain | 1128 - 1197 | IPR004087-14 |
| domain | K Homology domain, type 1 | 153 - 212 | IPR004088-1 |
| domain | K Homology domain, type 1 | 224 - 284 | IPR004088-2 |
| domain | K Homology domain, type 1 | 297 - 356 | IPR004088-3 |
| domain | K Homology domain, type 1 | 367 - 424 | IPR004088-4 |
| domain | K Homology domain, type 1 | 438 - 497 | IPR004088-5 |
| domain | K Homology domain, type 1 | 511 - 570 | IPR004088-6 |
| domain | K Homology domain, type 1 | 583 - 644 | IPR004088-7 |
| domain | K Homology domain, type 1 | 656 - 704 | IPR004088-8 |
| domain | K Homology domain, type 1 | 735 - 791 | IPR004088-9 |
| domain | K Homology domain, type 1 | 804 - 866 | IPR004088-10 |
| domain | K Homology domain, type 1 | 877 - 969 | IPR004088-11 |
| domain | K Homology domain, type 1 | 975 - 1036 | IPR004088-12 |
| domain | K Homology domain, type 1 | 1057 - 1120 | IPR004088-13 |
| domain | K Homology domain, type 1 | 1133 - 1193 | IPR004088-14 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| polysome | A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| mRNA binding | Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q24009 | BicC | Protein bicaudal C | Drosophila melanogaster (Fruit fly) | PR |
| Q00341 | HDLBP | Vigilin | Homo sapiens (Human) | PR |
| Q8VDJ3 | Hdlbp | Vigilin | Mus musculus (Mouse) | PR |
| Q9Z1A6 | Hdlbp | Vigilin | Rattus norvegicus (Rat) | PR |
| P34307 | C06G4.1 | KH domain-containing protein C06G4.1 | Caenorhabditis elegans | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSSVAVLTQE | SFAEHRSGLT | QQQVKVTALN | SEEENDPPTY | KEAFPPLPEK | APCLEAAQEP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SGPWSKIRPI | KASVITQVFH | VPLEERKYKD | MNQFGEGEQA | KICLDIMQKT | GAHLELSLAK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DQGLSIMVSG | KLEAVMKARK | EIVARLQTQA | SATVAIPKEH | HRFVIGKNGE | KLQDLELKTA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TKIQIPRPDD | PSNQIKITGT | KEGIEKARHE | ILLISAEQDK | RAVERLDVEK | VYHPFIAGPY |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NKLVSELMQD | TGTRINIPPP | SVNKTEIVFT | GEKEQLAQAV | ARVKKIYEEK | KKKTTTIAVE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VKKSQHKYVI | GRKGNSLQEI | LEKTGVSVEI | PPTDSSSETV | ILRGEPEKLG | QALTEVYAKA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| NSFTVSSVSA | PSWLHRFIIG | LFGQNLAKIT | QQMPKIHIEF | TEGEDKITSE | GPTEDVNVAQ |
| 430 | 440 | 450 | 460 | 470 | 480 |
| EQIEVMVKDL | INRTDYAEIN | VDHKFHRHLI | GKNGANINRI | KDLYKVSVRI | PPDNEKSNLI |
| 490 | 500 | 510 | 520 | 530 | 540 |
| RIEGDPQGVQ | QAKKELLELA | SRMENERTKD | LIIEQKFHRT | IIGQKGERIR | EIREKFPEVI |
| 550 | 560 | 570 | 580 | 590 | 600 |
| INFPDPAHKS | DIVQLRGPKN | EVEKCTKYMQ | KMVADLVENS | FSISVPIFKQ | FHKNIIGKGG |
| 610 | 620 | 630 | 640 | 650 | 660 |
| ANIKKIREES | NTKIDLPGRE | QATQRQLLSQ | GREQTVKLLR | HRILAIQKEL | ANITEVEVSI |
| 670 | 680 | 690 | 700 | 710 | 720 |
| PSKLHNSLIG | AKGRFIRSIM | EECGGVHIHF | PTEGSGSATV | TIRAQPRTWR | KPRSSCCTWA |
| 730 | 740 | 750 | 760 | 770 | 780 |
| EEKQTKSYTV | DLRAKPEYHK | FLIGKGGGNI | RKVRDNTGAR | IIFPTSEDKD | QELITIMGTE |
| 790 | 800 | 810 | 820 | 830 | 840 |
| EAVKEAQKEL | EALIKNLDNV | VEDSMVVDPK | HHRHFVIRRG | QVLREIADEY | GGVMVRLPTV |
| 850 | 860 | 870 | 880 | 890 | 900 |
| SGTQSDKVTL | KGAKDCVEAA | KKRIQEIIED | LEAQVTIECT | IPQKFHRSIM | GPKGSRIQQI |
| 910 | 920 | 930 | 940 | 950 | 960 |
| TRDYGVQIKF | PDREENPAPV | AEPALQENGE | EGGEGKDGKD | ADPSSPRKCD | IIIISGRREK |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| CEAAKEALQA | LVPVTIEVEV | PFDLHRYIIG | QKGSGIRKMM | DEFEVNIQVP | APELQSSDII |
| 1030 | 1040 | 1050 | 1060 | 1070 | 1080 |
| TITGLAANLD | RAKAGLLERV | KELQAEQEDR | ALRSFKLTVT | VDPKYHPKII | GRKGAVITQI |
| 1090 | 1100 | 1110 | 1120 | 1130 | 1140 |
| RTEHEVNIQF | PDKDDESQAQ | DQITITGYEK | NAEAARDAIM | KIVGELEQMV | SEDVTLDHRV |
| 1150 | 1160 | 1170 | 1180 | 1190 | 1200 |
| HARIIGARGK | AIRKIMDEFK | VDIRFPQSGA | PDPNCVTVTG | LPENVEEAID | HILNLEEEYL |
| 1210 | 1220 | 1230 | 1240 | 1250 | 1260 |
| ADVVDNEAMQ | VYMKPSSHEE | SKVPSKGFVV | RDAPCGTVNN | EKAPDMSSSE | DFPSFGAQVA |
| PKTLPWGPKR |