Q24009
Gene name |
BicC (CG4824) |
Protein name |
Protein bicaudal C |
Names |
|
Species |
Drosophila melanogaster (Fruit fly) |
KEGG Pathway |
dme:Dmel_CG4824 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q24009
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q24009-F1 | Predicted | AlphaFoldDB |
No variants for Q24009
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q24009 | |||||
No associated diseases with Q24009
9 regional properties for Q24009
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Sterile alpha motif domain | 802 - 868 | IPR001660 |
| domain | K Homology domain | 171 - 244 | IPR004087-1 |
| domain | K Homology domain | 323 - 397 | IPR004087-2 |
| domain | K Homology domain, type 1 | 176 - 240 | IPR004088-1 |
| domain | K Homology domain, type 1 | 327 - 392 | IPR004088-2 |
| domain | BICC1, SAM domain | 805 - 868 | IPR037974 |
| domain | BICC1, first type I KH domain | 85 - 166 | IPR047549 |
| domain | BICC1, third type I KH domain | 325 - 393 | IPR047553 |
| domain | BICC1, second type I KH | 171 - 240 | IPR047554 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| mRNA binding | Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns. |
7 GO annotations of biological process
| Name | Definition |
|---|---|
| actin cytoskeleton organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. |
| microtubule cytoskeleton organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. |
| mitotic cell cycle | Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent. |
| negative regulation of oskar mRNA translation | Any process that stops, prevents or reduces the rate that oskar mRNAs are effectively translated into protein. |
| oogenesis | The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster. |
| ovarian follicle cell migration | The directed movement of an ovarian follicle cell that takes place during oogenesis. During egg chamber formation, follicle cells migrate to envelop the germ-line cysts and move in between cysts. At stage 10B, follicle cells migrate centripetally between the nurse cells and the oocyte, enclosing the anterior of the egg. An example of this is found in Drosophila melanogaster. |
| protein localization | Any process in which a protein is transported to, or maintained in, a specific location. |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P81021 | HDLBP | Vigilin | Gallus gallus (Chicken) | PR |
| Q00341 | HDLBP | Vigilin | Homo sapiens (Human) | PR |
| Q8VDJ3 | Hdlbp | Vigilin | Mus musculus (Mouse) | PR |
| Q9Z1A6 | Hdlbp | Vigilin | Rattus norvegicus (Rat) | PR |
| P34307 | C06G4.1 | KH domain-containing protein C06G4.1 | Caenorhabditis elegans | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLSCASFNKL | MYPSAADVAK | PPMVGLEVEA | GSIGSLSSLH | ALPSTTSVGS | GAPSETQSEI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SSVDSDWSDI | RAIAMKLGVQ | NPDDLHTERF | KVDRQKLEQL | IKAESSIEGM | NGAEYFFHDI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| MNTTDTYVSW | PCRLKIGAKS | KKDPHVRIVG | KVDQVQRAKE | RILSSLDSRG | TRVIMKMDVS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| YTDHSYIIGR | GGNNIKRIMD | DTHTHIHFPD | SNRSNPTEKS | NQVSLCGSLE | GVERARALVR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LSTPLLISFE | MPVMGPNKPQ | PDHETPYIKM | IETKFNVQVI | FSTRPKLHTS | LVLVKGSEKE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SAQVRDATQL | LINFACESIA | SQILVNVQME | ISPQHHEIVK | GKNNVNLLSI | MERTQTKIIF |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PDLSDMNVKP | LKKSQVTISG | RIDDVYLARQ | QLLGNLPVAL | IFDFPDNHND | ASEIMSLNTK |
| 430 | 440 | 450 | 460 | 470 | 480 |
| YGVYITLRQK | QRQSTLAIVV | KGVEKFIDKI | YEARQEILRL | ATPFVKPEIP | DYYFMPKDKD |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LNLAYRTQLT | ALLAGYVDSP | KTPSLLPPSL | AGQLTPYANN | NHLLLNANGL | ATPTGVCAPT |
| 550 | 560 | 570 | 580 | 590 | 600 |
| QKYMQLHNSF | QQAQNRSMVA | GGQSNNGNYL | QVPGAVAPPL | KPPTVSPRNS | CSQNTSGYQS |
| 610 | 620 | 630 | 640 | 650 | 660 |
| FSSSTTSLEQ | SYPPYAQLPG | TVSSTSSSTA | GSQNRAHYSP | DSTYGSEGGG | VGGGGGGGAR |
| 670 | 680 | 690 | 700 | 710 | 720 |
| LGRRLSDGVL | LGLSNSNGGG | GNSGGAHLLP | GSAESYRSLH | YDLGGNKHSG | HRAFDFDMKR |
| 730 | 740 | 750 | 760 | 770 | 780 |
| ALGYKAMERT | PVAGELRTPT | TAWMGMGLSS | TSPAPAPLEN | GENGAAGGGA | SSGWRLPPGL |
| 790 | 800 | 810 | 820 | 830 | 840 |
| GSPYGLSATT | GLLDATPVNR | RMQLAKHKDI | QTLLTSLGLE | HYIKIFVLNE | IDLEVFTTLT |
| 850 | 860 | 870 | 880 | 890 | 900 |
| EENLMELGIA | AFGARKKLLT | AIHTLLANEA | ACSTMPSSSS | SQNSSSPRFS | GSAAPGAERR |
| PSNQW |