AiPD: Autoinhibited Protein Database

P10586

Gene name	PTPRF (LAR)
Protein name	Receptor-type tyrosine-protein phosphatase F
Names	Leukocyte common antigen related, LAR
Species	Homo sapiens (Human)
KEGG Pathway	hsa:5792
EC number	3.1.3.48: Phosphoric monoester hydrolases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1283-1357 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

1283-1357 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

14 structures for P10586

Entry ID	Method	Resolution	Chain	Position	Source
1LAR	X-ray	200 A	A/B	1333-1907	PDB
2DJU	NMR	-	A	319-411	PDB
2DN7	NMR	-	A	821-914	PDB
2EDX	NMR	-	A	596-716	PDB
2EDY	NMR	-	A	915-1010	PDB
2YD5	X-ray	220 A	A	29-231	PDB
2YD8	X-ray	205 A	A	29-231	PDB
4N5U	X-ray	146 A	A	601-705	PDB
6KR4	X-ray	285 A	A/B/C/D	1332-1907	PDB
6TPT	X-ray	320 A	A	512-706	PDB
6TPU	X-ray	155 A	A/B	513-706	PDB
6TPV	X-ray	180 A	A/B	319-512	PDB
6TPW	X-ray	290 A	A	319-706	PDB
AF-P10586-F1	Predicted				AlphaFoldDB

1579 variants for P10586

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
rs1131692054 RCV000144043	616	V>missing	Breasts and/or nipples, aplasia or hypoplasia of, 2 [ClinVar]	Yes	ClinVar dbSNP
RCV000986294 rs145235828 CA813459	1730	H>Q	Breasts and/or nipples, aplasia or hypoplasia of, 2 [ClinVar]	Yes	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA339988609 rs1284169835	2	A>T		No	ClinGen gnomAD
CA339988623 rs1445843642	3	P>L		No	ClinGen gnomAD
rs1212651831 CA339988627	4	E>K		No	ClinGen gnomAD
rs766928002 CA811677	6	A>D		No	ClinGen ExAC gnomAD
rs766928002 CA811676	6	A>V		No	ClinGen ExAC gnomAD
CA339988719 rs1379181132	9	R>W		No	ClinGen TOPMed
CA811679 rs376974470	10	T>M		No	ClinGen ESP ExAC TOPMed gnomAD
CA811678 rs376974470	10	T>R		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	14	L>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA21653742 rs373829166 CA811681	15	V>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs373829166 CA811680	15	V>M		No	ClinGen ESP ExAC TOPMed gnomAD
rs563605163 CA811683	16	P>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs780606374 CA811682	16	P>S		No	ClinGen ExAC gnomAD
rs1384122242 CA339988848	17	A>T		No	ClinGen gnomAD
CA811685 rs117228743	19	V>M		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA339988940 rs1246885392	20	M>I		No	ClinGen TOPMed
rs1451378674 CA339989021	25	A>T		No	ClinGen gnomAD
CA339989048 rs1312482627	26	G>D		No	ClinGen gnomAD
CA811687 rs142286926	27	A>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs1278488146 CA339989076	27	A>V		No	ClinGen gnomAD
rs1225917677 CA339989127	29	G>V		No	ClinGen gnomAD
rs763748777 CA811696	31	S>R		No	ClinGen ExAC TOPMed gnomAD
rs750930855 CA811697	35	F>S		No	ClinGen ExAC gnomAD
CA811698 rs556396767	36	I>F		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA339991887 rs1453417778	36	I>T		No	ClinGen gnomAD
CA21660432 rs937131934	38	V>F		No	ClinGen TOPMed gnomAD
TCGA novel	39	P>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA811699 rs780553041	41	D>N		No	ClinGen ExAC gnomAD
rs909321178 CA21660440	43	T>I		No	ClinGen TOPMed
rs747392641 CA811700	44	G>W		No	ClinGen ExAC gnomAD
rs1049277336 CA21660455	47	G>R		No	ClinGen gnomAD
rs781508066 CA811702	50	A>V		No	ClinGen ExAC gnomAD
CA339992189 rs1321313292	51	S>F		No	ClinGen TOPMed
rs748125986 CA339992223	52	F>L		No	ClinGen ExAC TOPMed gnomAD
CA21660494 rs556629491	53	V>E		No	ClinGen Ensembl
CA811704 rs576238237	53	V>M		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA811706 rs565068107	57	T>A		No	ClinGen 1000Genomes ExAC gnomAD
rs940364059 CA21660514	57	T>R		No	ClinGen Ensembl
rs868728182 CA21660516	58	G>E		No	ClinGen Ensembl
rs770909342 CA811707	60	P>H		No	ClinGen ExAC gnomAD
rs774071378 CA811708	61	K>Q		No	ClinGen ExAC gnomAD
rs374024117 CA811709	62	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs1160984093 CA339992559	63	R>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs1557695030 CA339992625	65	T>K		No	ClinGen Ensembl
CA339992686 rs775187760 CA811711	67	M>L		No	ClinGen ExAC TOPMed gnomAD
CA811712 rs760287504	71	K>E		No	ClinGen ExAC TOPMed gnomAD
CA339992930 rs1189436278	76	Q>L		No	ClinGen gnomAD
rs367865707 CA811714	77	R>H	Variant assessed as Somatic; 0.0006025 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs34596002 CA21660595	79	E>K		No	ClinGen Ensembl
rs369031094 CA811731	81	I>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA339993302 rs1346277417	84	D>G		No	ClinGen TOPMed gnomAD
rs1399064221 CA339993346	85	D>V		No	ClinGen TOPMed
CA339993364 rs1287440506	86	G>E		No	ClinGen TOPMed gnomAD
COSM3728249 rs954717138 CA21660767	86	G>R	haematopoietic_and_lymphoid_tissue [Cosmic]	No	ClinGen cosmic curated TOPMed gnomAD
CA811734 rs761438626	91	L>V		No	ClinGen ExAC gnomAD
CA811735 rs202216979	92	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
CA811737 rs752081368	97	R>G		No	ClinGen ExAC TOPMed gnomAD
rs767916955 CA811738	97	R>Q		No	ClinGen ExAC gnomAD
rs752081368 CA811736	97	R>W		No	ClinGen ExAC TOPMed gnomAD
CA811740 rs756266392	98	V>A		No	ClinGen ExAC gnomAD
CA339993624 CA339993627 rs1265936350	98	V>L		No	ClinGen TOPMed gnomAD
rs371678029 CA811742	100	R>Q	Variant assessed as Somatic; 4.621e-05 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	103	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	104	I>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs757312037 CA811743	105	Y>C		No	ClinGen ExAC gnomAD
rs571501672 CA811745	106	E>D		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA811744 rs778902441	106	E>K		No	ClinGen ExAC gnomAD
CA339993862 rs758327132	108	T>I		No	ClinGen ExAC
CA811746 rs758327132	108	T>R		No	ClinGen ExAC
CA21660835 rs774033930	110	T>A		No	ClinGen Ensembl
TCGA novel	114	G>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA339994233 rs1443865876	121	K>E		No	ClinGen TOPMed
CA811748 rs527385217	121	K>R		No	ClinGen 1000Genomes ExAC gnomAD
CA811750 COSM177481 rs776445536	126	E>K	large_intestine [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
CA811781 rs750476610	128	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA21676532 rs981152996	129	Q>E		No	ClinGen Ensembl
CA339999233 rs1306598175	129	Q>H		No	ClinGen gnomAD
CA811783 rs766528777	131	P>A		No	ClinGen ExAC gnomAD
CA811784 rs751509707	131	P>L		No	ClinGen ExAC gnomAD
CA21676549 rs1034102532	132	P>A		No	ClinGen Ensembl
rs755030848 CA811785	132	P>L		No	ClinGen ExAC TOPMed gnomAD
rs777318046 COSM3419254 CA811789	138	D>N	large_intestine Variant assessed as Somatic; 4.637e-05 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA811791 rs770321096	139	M>I		No	ClinGen ExAC gnomAD
rs1425153166 CA339999449	139	M>R		No	ClinGen gnomAD
CA811790 rs749022267	139	M>V		No	ClinGen ExAC gnomAD
CA21676591 rs962585204	142	Q>*		No	ClinGen Ensembl
CA339999608 rs1432596269	146	V>A		No	ClinGen gnomAD
CA339999650 rs1170631763	149	A>T		No	ClinGen TOPMed
CA21676609 rs749276357	150	R>H	Variant assessed as Somatic; 4.62e-05 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1359561471 CA339999704	152	A>G		No	ClinGen gnomAD
CA811795 rs569999879	152	A>T		No	ClinGen 1000Genomes ExAC
CA339999715 rs1288313499	153	T>A		No	ClinGen gnomAD
rs374531518 CA811797	153	T>I		No	ClinGen ESP ExAC gnomAD
rs960194475 CA21676627	154	M>I		No	ClinGen TOPMed gnomAD
rs773282232 CA811798	155	L>V		No	ClinGen ExAC TOPMed gnomAD
CA811800 rs375157244	158	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA811801 rs368326365	159	G>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA811803 rs370860175	160	G>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs755880536 CA811805	165	E>D		No	ClinGen ExAC gnomAD
TCGA novel	168	W>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs777667224 CA811807	172	F>V		No	ClinGen ExAC gnomAD
CA811808 rs368692509	173	L>F		No	ClinGen ESP ExAC gnomAD
rs756996085 CA811809	174	P>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA811810 rs778340007	176	D>A		No	ClinGen ExAC gnomAD
rs1281980017 CA340000137	177	P>A		No	ClinGen gnomAD
CA340000140 rs1353396650	177	P>L		No	ClinGen gnomAD
CA811812 rs150660901	179	T>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA340000170 rs1206019354	180	S>G		No	ClinGen TOPMed gnomAD
rs748737963 CA811814	180	S>I		No	ClinGen ExAC gnomAD
rs748737963 CA340000174	180	S>N		No	ClinGen ExAC gnomAD
CA21676683 rs555893108	181	N>D		No	ClinGen gnomAD
CA21676685 rs1050427151	181	N>S		No	ClinGen gnomAD
CA811816 rs773693327	182	G>S		No	ClinGen ExAC TOPMed gnomAD
CA340000200 rs1455417237	183	R>C		No	ClinGen gnomAD
rs771288963 CA811818	183	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1275911329 CA340000227	185	K>R		No	ClinGen gnomAD
TCGA novel	187	L>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs774501830 CA811819	188	R>H		No	ClinGen ExAC TOPMed gnomAD
rs1385310531 CA340003035	194	I>V		No	ClinGen gnomAD
TCGA novel	195	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1383530919 CA340003250	198	E>*		No	ClinGen Ensembl
CA21683799 rs139518625	202	Q>*		No	ClinGen ESP TOPMed
CA21683788 rs139518625	202	Q>E		No	ClinGen ESP TOPMed
CA811867 rs759104730	204	K>N		No	ClinGen ExAC gnomAD
CA811869 rs754335848	206	E>*		No	ClinGen ExAC gnomAD
rs757899600 CA811870	209	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA811872 rs750826620	210	T>A		No	ClinGen ExAC TOPMed gnomAD
CA811873 rs758657312	212	S>L		No	ClinGen ExAC TOPMed gnomAD
CA340003744 rs1161939784	214	G>D		No	ClinGen gnomAD
rs747245021 CA811875	215	T>A		No	ClinGen ExAC gnomAD
CA340003809 COSM72349 rs906834223	216	R>H	ovary Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated NCI-TCGA TOPMed gnomAD
CA21683873 rs906834223	216	R>L		No	ClinGen TOPMed gnomAD
TCGA novel	221	A>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA811876 rs768752897	221	A>V		No	ClinGen ExAC TOPMed gnomAD
CA21683894 rs1035295037	222	N>Y		No	ClinGen TOPMed
rs1453668088 CA340004166	225	V>L		No	ClinGen gnomAD
CA340004180 rs1377104184	226	R>Q		No	ClinGen gnomAD
rs1330678973 CA339984147	228	R>C		No	ClinGen gnomAD
CA339984154 rs1455359848	228	R>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA339984177 rs1250737549	229	R>H		No	ClinGen TOPMed
TCGA novel	230	V>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA339984181 rs1299856963	230	V>M		No	ClinGen gnomAD
CA339984207 rs1369116115	231	A>D		No	ClinGen gnomAD
CA339984214 rs1468296025	232	P>S		No	ClinGen TOPMed
TCGA novel	233	R>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs201549619 CA21644021	233	R>H		No	ClinGen gnomAD
rs775888535 CA811951	235	S>C		No	ClinGen ExAC gnomAD
CA21644028 rs370982565	237	P>S		No	ClinGen ESP TOPMed gnomAD
CA21644034 rs969964085	240	S>I		No	ClinGen gnomAD
CA339984448 rs969964085	240	S>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA339984496 rs1198021971	241	Q>E		No	ClinGen TOPMed
CA339984552 rs1450640377	242	E>K		No	ClinGen gnomAD
TCGA novel	245	P>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs764333630 CA811953	247	G>S		No	ClinGen ExAC TOPMed gnomAD
rs1459942101 CA339984727	248	S>N		No	ClinGen gnomAD
rs1167481147 CA339984765	249	V>M		No	ClinGen gnomAD
rs753909516 CA21644051	251	L>V		No	ClinGen ExAC TOPMed gnomAD
CA811955 rs568517762	254	V>M		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA811956 rs765398408	255	A>S		No	ClinGen ExAC
CA339985013 rs951731461	258	A>G		No	ClinGen Ensembl
CA21644092 rs951731461	258	A>V		No	ClinGen Ensembl
CA339985028 rs1322773479	259	P>A		No	ClinGen gnomAD
rs1570367348 CA339985063	260	M>L		No	ClinGen Ensembl
CA811959 rs368337407	263	V>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA811960 rs751403337	264	K>Q		No	ClinGen ExAC gnomAD
CA811961 rs754635285	266	M>V		No	ClinGen ExAC TOPMed gnomAD
CA21644130 rs983179950	267	M>L		No	ClinGen gnomAD
rs1302980890 CA339985381	268	G>R		No	ClinGen TOPMed
rs142181863 CA811962	270	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA339985562 rs1392922009	272	L>F		No	ClinGen TOPMed
rs747883338 CA811963	273	T>I		No	ClinGen ExAC TOPMed gnomAD
rs747883338 CA21644174	273	T>S		No	ClinGen ExAC TOPMed gnomAD
CA811964 rs769151984	274	K>E		No	ClinGen ExAC gnomAD
rs1454126684 CA339985731	277	E>K		No	ClinGen TOPMed
rs746345482 CA811966	278	M>T		No	ClinGen ExAC gnomAD
CA339985855 rs1187315874	279	P>S		No	ClinGen gnomAD
rs772578571 CA811967	280	V>I		No	ClinGen ExAC gnomAD
CA21644180 rs764349921	282	R>H		No	ClinGen gnomAD
rs775794645 CA21644181	283	N>K		No	ClinGen ExAC TOPMed gnomAD
rs140415781 CA811969	284	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs769061275 CA811970	287	L>V		No	ClinGen ExAC gnomAD
CA339986236 rs1250419972	288	S>N		No	ClinGen TOPMed
CA811971 rs776690110	289	N>H		No	ClinGen ExAC gnomAD
TCGA novel	290	V>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	291	V>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs765219893 CA811973	291	V>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA811974 rs557357295	292	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
CA811975 rs762919783	292	R>H		No	ClinGen ExAC TOPMed gnomAD
rs557357295 CA339986344	292	R>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA811976 rs766448564	294	A>T		No	ClinGen ExAC gnomAD
rs751350194 CA811977	295	N>S		No	ClinGen ExAC TOPMed gnomAD
CA339986558 rs1269794866	299	V>M		No	ClinGen gnomAD
TCGA novel	300	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs781081287 CA811979	303	S>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs866203596 CA21644227	305	G>D		No	ClinGen Ensembl
rs751608837 CA21644232	308	E>K		No	ClinGen Ensembl
rs1200604615 CA339987006	310	T>P		No	ClinGen gnomAD
CA339987121 rs1256050298	315	V>M		No	ClinGen gnomAD
rs1474519709 CA339987169	316	K>N		No	ClinGen TOPMed gnomAD
CA339987185 rs1184703085	317	A>P		No	ClinGen TOPMed gnomAD
CA21645348 rs182835593	318	L>P		No	ClinGen 1000Genomes TOPMed
CA812002 rs753539551	319	P>L		No	ClinGen ExAC TOPMed gnomAD
rs756729737 CA812003	321	P>S		No	ClinGen ExAC gnomAD
CA339989311 rs756729737	321	P>T		No	ClinGen ExAC gnomAD
rs778462451 CA812004	322	P>L		No	ClinGen ExAC gnomAD
CA812006 rs755526598	325	L>V		No	ClinGen ExAC gnomAD
CA812007 rs781347680	326	V>M		No	ClinGen ExAC TOPMed gnomAD
rs1342143736 CA339989522	328	T>S		No	ClinGen gnomAD
CA339989529 rs1288701467	329	E>Q		No	ClinGen TOPMed
rs748578998 CA812008	330	T>A		No	ClinGen ExAC TOPMed gnomAD
CA812009 rs769856471	330	T>R		No	ClinGen ExAC TOPMed gnomAD
rs1570395587 CA339989610	331	T>P		No	ClinGen Ensembl
CA339989700 rs1190811308	333	T>I		No	ClinGen gnomAD
rs773543094 CA812010	335	V>I		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	336	T>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA812011 rs749558306	336	T>I		No	ClinGen ExAC gnomAD
rs1570395690 CA339989760	336	T>P		No	ClinGen Ensembl
CA812012 rs771125743	337	L>F		No	ClinGen ExAC gnomAD
rs771125743 CA812013	337	L>I		No	ClinGen ExAC gnomAD
rs1570395886 CA339989810	338	T>I		No	ClinGen Ensembl
rs1351426605 CA339989860	340	D>E		No	ClinGen gnomAD
rs1168007555 CA339989843	340	D>Y		No	ClinGen gnomAD
rs767493242 CA812015	342	G>V		No	ClinGen ExAC gnomAD
rs1570396022 CA339989925	343	N>T		No	ClinGen Ensembl
rs895500892 CA21645441	344	S>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs775100398 CA812016	344	S>P		No	ClinGen ExAC gnomAD
CA339990040 rs1557787647	346	P>A		No	ClinGen Ensembl
rs1410741955 CA339990118	348	T>N		No	ClinGen TOPMed
rs1570396352 CA339990107	348	T>P		No	ClinGen Ensembl
rs1292708024 CA339990154	349	Y>H		No	ClinGen gnomAD
CA812019 rs753484573	349	Y>S		No	ClinGen ExAC gnomAD
CA339990231 rs1570396539	351	G>A		No	ClinGen Ensembl
rs563115918 CA812021	353	Q>R		No	ClinGen 1000Genomes ExAC gnomAD
TCGA novel	354	Y>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1570396628 CA339990302	354	Y>S		No	ClinGen Ensembl
rs143362739 CA812022	355	R>C		No	ClinGen ESP ExAC TOPMed gnomAD
CA812024 rs540408475	355	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA gnomAD
rs143362739 CA812023	355	R>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA812026 RCV000910250 rs79621077	356	A>S		No	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA339990336 rs79621077	356	A>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs368187251 CA812027	356	A>V		No	ClinGen ESP ExAC gnomAD
rs749507478 CA812028	357	A>P		No	ClinGen ExAC TOPMed gnomAD
CA812029 rs142785985 COSM1582248	357	A>V	stomach [Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD
CA812032 rs772095405	359	T>M		No	ClinGen ExAC TOPMed gnomAD
CA339990392 rs772095405	359	T>R		No	ClinGen ExAC TOPMed gnomAD
rs1286468849 CA339990423	360	E>D		No	ClinGen gnomAD
rs1557788056 CA339990403	360	E>K		No	ClinGen Ensembl
rs781534278 CA21645476	361	G>D		No	ClinGen Ensembl
CA812034 rs760597858	361	G>S		No	ClinGen ExAC gnomAD
rs761391796 CA812037	364	Q>L		No	ClinGen ExAC gnomAD
rs1331433592 CA339990550	365	E>G		No	ClinGen gnomAD
rs1570397540 CA339990646	369	V>G		No	ClinGen Ensembl
CA339990657 rs1379971160	370	A>S		No	ClinGen gnomAD
CA339990670 rs1570397632	371	T>P		No	ClinGen Ensembl
rs765844810 CA812041	373	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1212415516 CA339990737	375	S>G		No	ClinGen gnomAD
CA339990769 rs1239117562	376	I>V		No	ClinGen gnomAD
COSM681273 CA339990820 rs1186911250	378	G>S	lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated NCI-TCGA gnomAD
rs1229058695 CA339990837	379	L>R		No	ClinGen TOPMed
CA339990864 rs1415425444	382	F>S		No	ClinGen gnomAD
CA812045 rs756633630	383	S>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA339990928 rs1557788505	387	F>L		No	ClinGen Ensembl
rs376580480 CA812048	388	R>C		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs779257179 CA812050	388	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs779257179 CA812049	388	R>L		No	ClinGen ExAC TOPMed gnomAD
rs571781315 CA812052	391	A>S		No	ClinGen 1000Genomes ExAC gnomAD
rs746910917 COSM1193891 CA812053	391	A>V	lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs1279183680 CA339991018	393	N>K		No	ClinGen gnomAD
rs776374379 CA339991033	394	S>I		No	ClinGen ExAC TOPMed gnomAD
rs776374379 CA339991030	394	S>N		No	ClinGen ExAC TOPMed gnomAD
CA812055 rs776374379	394	S>T		No	ClinGen ExAC TOPMed gnomAD
CA812058 rs772886593	397	R>Q		No	ClinGen ExAC gnomAD
rs61733187 CA812059	399	P>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1210046572 CA339991111	399	P>T		No	ClinGen gnomAD
CA812062 rs761196800	400	P>A		No	ClinGen ExAC TOPMed gnomAD
CA812063 rs764728270	401	S>G		No	ClinGen ExAC gnomAD
rs754204068 CA339991167	401	S>R		No	ClinGen ExAC TOPMed gnomAD
CA812065 rs757666619 COSM681272	402	E>K	lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
rs1433610918 CA339991206	403	A>S		No	ClinGen gnomAD
CA21645643 rs1034684585	404	V>A		No	ClinGen Ensembl
rs760127576 CA21645654	405	R>Q		No	ClinGen Ensembl
rs547221830 CA812067	405	R>W		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs758562785 CA812068	406	A>S		No	ClinGen ExAC TOPMed gnomAD
rs748429132 COSM1222633 CA812069	407	R>C	large_intestine central_nervous_system [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
rs748429132 CA21645692	407	R>G		No	ClinGen ExAC TOPMed gnomAD
rs373662568 CA812071	407	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs748429132 CA812070	407	R>S		No	ClinGen ExAC TOPMed gnomAD
rs748121483 CA812073	408	T>M		No	ClinGen ExAC TOPMed gnomAD
rs1347204574 CA339991340	410	E>G		No	ClinGen gnomAD
CA812075 rs772934252	411	Q>H		No	ClinGen ExAC gnomAD
rs1186829781 CA339991371	412	A>P		No	ClinGen TOPMed gnomAD
CA339991373 rs1186829781	412	A>S		No	ClinGen TOPMed gnomAD
TCGA novel	412	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA812076 VAR_054766 rs1065775	412	A>V		No	ClinGen UniProt ExAC TOPMed dbSNP gnomAD
rs1205526671 CA339991390	413	P>L		No	ClinGen gnomAD
rs369985213 CA21645716	416	P>S		No	ClinGen ESP TOPMed gnomAD
rs17849128 CA21645718	417	P>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
rs759136731 CA812079	418	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA
rs372477577 CA812080	418	R>H		No	ClinGen ESP ExAC TOPMed gnomAD
CA339991466 rs1453259016	419	R>C	Variant assessed as Somatic; 8.11e-05 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs536262487 CA812082	419	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA gnomAD
rs375757987 CA812084	420	V>M		No	ClinGen ESP ExAC gnomAD
CA339991491 rs1394757550	421	Q>K		No	ClinGen gnomAD
rs1471991235 CA339991508	423	R>C		No	ClinGen TOPMed
CA339991517 rs1360467408	423	R>H		No	ClinGen gnomAD
TCGA novel	424	M>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA812087 rs751831806	427	A>P		No	ClinGen ExAC TOPMed gnomAD
rs751831806 CA339991563	427	A>T		No	ClinGen ExAC TOPMed gnomAD
CA339991567 rs1299928013	427	A>V		No	ClinGen gnomAD
rs1215117006 CA339991607	430	M>V		No	ClinGen TOPMed
rs1250735663 CA339991637	432	V>M		No	ClinGen gnomAD
rs1211482971 CA339991652	433	Q>*		No	ClinGen gnomAD
CA21645754 rs942716991	433	Q>H		No	ClinGen gnomAD
CA339991657 rs1292246821	433	Q>R		No	ClinGen TOPMed
rs755017217 CA812088	436	P>L		No	ClinGen ExAC gnomAD
CA339991801 rs1570401727	438	E>D		No	ClinGen Ensembl
rs1054446954 CA21645759	438	E>G		No	ClinGen TOPMed
CA21645758 rs931536811	438	E>K		No	ClinGen TOPMed gnomAD
rs931536811 CA339991753	438	E>Q		No	ClinGen TOPMed gnomAD
CA339991835 rs1450583445	439	E>D		No	ClinGen gnomAD
rs781314317 CA339991881	440	P>L		No	ClinGen ExAC TOPMed gnomAD
rs781314317 CA812089	440	P>R		No	ClinGen ExAC TOPMed gnomAD
CA339991839 rs1193066225	440	P>T		No	ClinGen gnomAD
rs1362908192 CA339991911	441	N>S		No	ClinGen TOPMed
TCGA novel	442	G>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1393940547 CA339991948	442	G>V		No	ClinGen gnomAD
CA812091 rs756055613	444	V>L		No	ClinGen ExAC gnomAD
CA339991974 rs756055613	444	V>M		No	ClinGen ExAC gnomAD
rs1004348611 CA21645762	445	R>Q		No	ClinGen TOPMed gnomAD
rs887284804 CA21645761	445	R>W		No	ClinGen TOPMed gnomAD
CA339992050 rs1246641379	446	G>R		No	ClinGen gnomAD
rs749068389 CA812093	448	R>C		No	ClinGen ExAC TOPMed gnomAD
rs770566976 CA812094	448	R>H		No	ClinGen ExAC gnomAD
CA812095 rs370471082	449	V>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1204098813 CA339992215	450	Y>*		No	ClinGen TOPMed gnomAD
CA812096 rs3748796 VAR_020299	450	Y>C		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs1003445552 CA21645784	450	Y>N		No	ClinGen Ensembl
TCGA novel	451	Y>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA21645788 rs958996158	452	T>S		No	ClinGen Ensembl
CA339992305 rs1426084669	453	P>A		No	ClinGen gnomAD
CA339992327 rs1189049815	453	P>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA339992411 rs1557790674	456	R>C		No	ClinGen Ensembl
CA812098 rs775153874	456	R>H		No	ClinGen ExAC gnomAD
rs1161603881 CA339992443	457	R>C		No	ClinGen gnomAD
CA812099 rs371589885	457	R>H		No	ClinGen ExAC TOPMed gnomAD
rs371589885 CA339992451	457	R>P		No	ClinGen ExAC TOPMed gnomAD
CA339992469 rs1453124855	458	P>S		No	ClinGen gnomAD
CA812100 rs765697855	459	P>L		No	ClinGen ExAC TOPMed gnomAD
CA339992510 rs1287200699	459	P>S		No	ClinGen TOPMed gnomAD
CA812102 rs763208022	460	N>S		No	ClinGen ExAC gnomAD
rs1231299958 CA339992571	461	A>T		No	ClinGen TOPMed gnomAD
rs918748407 CA21645828	463	H>Y		No	ClinGen gnomAD
rs1289821986 CA339992700	464	K>E		No	ClinGen gnomAD
rs934199065 CA21645830	465	H>Y		No	ClinGen TOPMed gnomAD
CA812104 rs751772672	466	N>K		No	ClinGen ExAC gnomAD
rs370654753 CA812106	468	D>N		No	ClinGen ESP ExAC gnomAD
CA812107 rs752774736	469	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA21645839 rs1031553811	469	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA21645843 rs956070708	471	L>F		No	ClinGen TOPMed gnomAD
CA21645846 rs992617145	471	L>P		No	ClinGen TOPMed
rs1156962444 CA339993002	472	L>F		No	ClinGen gnomAD
CA339993030 rs1379466189	473	T>M		No	ClinGen gnomAD
CA812113 rs150324325	475	V>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs150324325 CA812112	475	V>M		No	ClinGen ESP ExAC TOPMed gnomAD
rs1309628467 CA339993113	476	G>D		No	ClinGen gnomAD
rs1412636837 CA339993084	476	G>S		No	ClinGen TOPMed gnomAD
rs1490262416 CA339993205	479	L>P		No	ClinGen TOPMed
rs573761255 CA812115	485	S>N		No	ClinGen 1000Genomes ExAC gnomAD
rs1207652998 CA339993381	486	L>M		No	ClinGen gnomAD
rs768264448 CA812117	487	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA812118 rs773564240	487	R>H		No	ClinGen ExAC TOPMed gnomAD
CA812120 rs771184014	488	V>M		No	ClinGen ExAC gnomAD
CA21645937 rs930295481	489	L>H		No	ClinGen TOPMed
TCGA novel	489	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA21645946 rs946122334	490	A>S		No	ClinGen gnomAD
CA339993494 rs946122334	490	A>T		No	ClinGen gnomAD
CA339993503 rs1432823468	490	A>V		No	ClinGen gnomAD
CA339993538 rs1354879374 CA339993539	491	F>L		No	ClinGen TOPMed gnomAD
CA339993552 rs1296085702	492	T>I		No	ClinGen gnomAD
CA812121 rs774708497	492	T>S		No	ClinGen ExAC TOPMed gnomAD
rs375847889 CA812123	493	A>T		No	ClinGen 1000Genomes ESP ExAC gnomAD
CA21645957 rs887326029	493	A>V		No	ClinGen TOPMed gnomAD
CA812125 rs760647060 COSM3689708	494	V>M	large_intestine [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
CA812128 rs757233751	496	D>G		No	ClinGen ExAC gnomAD
CA812127 rs368501227	496	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA812130 rs750275015	498	P>L		No	ClinGen ExAC gnomAD
CA339993777 rs895065406	501	P>A		No	ClinGen TOPMed gnomAD
rs895065406 CA21646005	501	P>S		No	ClinGen TOPMed gnomAD
CA21646014 rs996952375	502	T>A		No	ClinGen TOPMed gnomAD
CA339993800 rs1188172215	502	T>I		No	ClinGen gnomAD
rs1427684895 CA339993864	504	Q>R		No	ClinGen gnomAD
CA339993873 rs1168074813	505	V>F		No	ClinGen gnomAD
CA812131 rs758079244	507	T>A		No	ClinGen ExAC gnomAD
CA339993958 rs1461665604	507	T>M		No	ClinGen TOPMed gnomAD
CA339995519 rs1570409758	513	A>S		No	ClinGen Ensembl
CA812155 rs747721714	513	A>V		No	ClinGen ExAC gnomAD
CA339995634 rs201705061	516	A>P		No	ClinGen ESP ExAC TOPMed gnomAD
CA339995638 rs201705061	516	A>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA812158 rs201705061	516	A>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs373978818 CA812159	516	A>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA21646278 rs369772044	518	F>L		No	ClinGen ESP TOPMed gnomAD
rs747134912 CA812161	519	Q>K		No	ClinGen ExAC TOPMed gnomAD
CA812163 rs778628256	521	E>K		No	ClinGen ExAC TOPMed gnomAD
CA812164 rs761933943	522	V>M		No	ClinGen ExAC TOPMed gnomAD
rs1348588531 CA339995896	524	S>W		No	ClinGen gnomAD
CA339995924 rs1282365635	525	D>G		No	ClinGen gnomAD
rs1483547386 CA339995989	526	T>S		No	ClinGen TOPMed
CA812170 rs754542750	529	Q>K		No	ClinGen ExAC TOPMed gnomAD
CA812171 rs368816972	530	L>F		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	531	S>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs200072533 CA812172	531	S>L		No	ClinGen ExAC TOPMed gnomAD
CA339996150 rs1225380934	532	W>*		No	ClinGen TOPMed
CA812173 rs755587343	534	L>V		No	ClinGen ExAC gnomAD
rs1343911221 CA339996210	535	P>L		No	ClinGen TOPMed
rs746359623 CA812175	535	P>S		No	ClinGen ExAC gnomAD
CA812176 rs139284587	536	P>A		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1339099962 CA339996229	536	P>R		No	ClinGen Ensembl
CA812177 rs780240989	537	Q>E		No	ClinGen ExAC gnomAD
rs914839750 CA339996243	537	Q>P		No	ClinGen gnomAD
rs914839750 CA21646313	537	Q>R		No	ClinGen gnomAD
rs747424443 CA812178	538	E>G		No	ClinGen ExAC gnomAD
CA812181 rs748453373	539	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs776883780 CA812180	539	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA21646328 rs370784590	540	I>M		No	ClinGen ESP TOPMed
CA812182 rs377374918	541	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs773435037 CA812183	542	M>L		No	ClinGen ExAC gnomAD
CA812184 rs762913708	542	M>T		No	ClinGen ExAC gnomAD
rs932846356 CA21646339	544	E>D		No	ClinGen TOPMed
rs200879907 CA812185	548	W>C		No	ClinGen 1000Genomes ExAC gnomAD
CA339996492 rs200147342	549	A>E		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA812186 rs200147342	549	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
CA339996506 rs1435718099	550	A>S		No	ClinGen TOPMed gnomAD
CA339996499 rs1435718099	550	A>T		No	ClinGen TOPMed gnomAD
rs926058235 CA21646354	551	E>K		No	ClinGen TOPMed
rs148716858 CA339996591 CA812189	552	D>E		No	ClinGen 1000Genomes ESP ExAC gnomAD
rs376335770 CA812190	553	E>K		No	ClinGen ESP ExAC TOPMed gnomAD
CA812191 rs763528233	554	D>E		No	ClinGen ExAC gnomAD
rs1192271277 CA339996638	555	Q>R		No	ClinGen gnomAD
CA339996923 rs1350824421	557	H>Y		No	ClinGen gnomAD
rs1205028109 CA339996959	558	K>R		No	ClinGen gnomAD
CA21646717 CA339996977 rs75561307	559	V>L		No	ClinGen Ensembl
rs756352829 CA812220	560	T>N		No	ClinGen ExAC gnomAD
rs3748800 VAR_020300 CA812222	562	D>N		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA812223 rs771037116	563	P>A		No	ClinGen ExAC gnomAD
CA812224 rs778917013	563	P>L		No	ClinGen ExAC TOPMed gnomAD
CA339997139 rs771037116	563	P>S		No	ClinGen ExAC gnomAD
rs372713942 CA812225	564	T>A		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA812226 rs541760221	565	S>F		No	ClinGen 1000Genomes ExAC gnomAD
rs1313265257 CA339997358	568	T>I		No	ClinGen TOPMed gnomAD
rs1393907999 CA339997382	569	L>Q		No	ClinGen gnomAD
rs201453872 CA812229	569	L>V		No	ClinGen 1000Genomes ExAC gnomAD
CA339997425 rs373396517	570	E>A		No	ClinGen ESP TOPMed gnomAD
CA21646808 rs373396517	570	E>G		No	ClinGen ESP TOPMed gnomAD
rs776265538 CA812230	573	K>R		No	ClinGen ExAC gnomAD
CA812231 rs530318417	574	P>A		No	ClinGen 1000Genomes ExAC gnomAD
rs1447021392 CA339997531	575	D>H		No	ClinGen TOPMed
CA812233 rs772605619	576	T>I		No	ClinGen ExAC gnomAD
rs764750522 CA812232	576	T>S		No	ClinGen ExAC gnomAD
CA21646823 rs1057374443	577	L>F		No	ClinGen Ensembl
rs758181842 CA812234	577	L>H		No	ClinGen ExAC TOPMed gnomAD
rs376375127 CA812235	579	R>C		No	ClinGen ESP ExAC TOPMed gnomAD
CA339997653 rs376375127	579	R>G		No	ClinGen ESP ExAC TOPMed gnomAD
CA812236 rs753304290	579	R>H		No	ClinGen ExAC TOPMed gnomAD
CA339997736 rs1418563085	581	Q>H		No	ClinGen gnomAD
CA812238 rs764618194	581	Q>R		No	ClinGen ExAC TOPMed gnomAD
rs11210882 CA21646837	583	A>G		No	ClinGen Ensembl
CA812239 rs147188221	585	R>C		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA812240 rs144513069	585	R>H		No	ClinGen ESP ExAC TOPMed gnomAD
rs1000899867 CA21646866	588	M>I		No	ClinGen TOPMed gnomAD
rs1327156374 CA339997979	588	M>V		No	ClinGen TOPMed
CA339998062 rs1570421590	590	V>G		No	ClinGen Ensembl
CA21646879 rs79766207 CA812245	590	V>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs79766207 CA21646878	590	V>M		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA812247 rs150963518	592	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA21646896 rs1026828350	593	F>L		No	ClinGen Ensembl
rs1373771874 CA339998114	593	F>S		No	ClinGen gnomAD
rs951219998 CA339998123	594	T>P		No	ClinGen Ensembl
rs951219998 CA21646904	594	T>S		No	ClinGen Ensembl
TCGA novel	596	T>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA339998174 rs1442498608	597	I>T		No	ClinGen TOPMed gnomAD
CA812251 rs762345034	597	I>V		No	ClinGen ExAC gnomAD
rs1020428969 CA21646912	599	A>T		No	ClinGen TOPMed
rs766024179 CA812252	600	R>C		No	ClinGen ExAC TOPMed gnomAD
CA812253 rs751589837	600	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs751589837 CA21646931	600	R>L		No	ClinGen ExAC TOPMed gnomAD
CA339998236 rs1254987769	602	A>T		No	ClinGen gnomAD
CA812254 rs761321345	602	A>V		No	ClinGen ExAC TOPMed gnomAD
rs754156472 CA812256	603	Q>E		No	ClinGen ExAC gnomAD
CA812257 rs757452368	603	Q>R		No	ClinGen ExAC gnomAD
TCGA novel	605	T>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1232705923 CA340000552	606	P>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
TCGA novel	607	S>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA21650496 rs868510741	607	S>P		No	ClinGen TOPMed gnomAD
CA340000588 rs1217817504	608	A>P		No	ClinGen gnomAD
CA340000586 rs1217817504	608	A>T		No	ClinGen gnomAD
rs1242703150 CA340000636	609	P>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA340000733 rs1475349786	611	Q>H		No	ClinGen gnomAD
rs1259101040 CA340000718	611	Q>P		No	ClinGen TOPMed gnomAD
rs1180724695 CA340000763	612	K>R		No	ClinGen gnomAD
CA340000795 rs1570482151	613	V>G		No	ClinGen Ensembl
CA21650539 rs369236165 CA21650530	614	M>I		No	ClinGen ESP TOPMed gnomAD
rs1363468504 CA340000808	614	M>T		No	ClinGen TOPMed
rs1387881232 CA340000841	615	C>F		No	ClinGen TOPMed
rs1160451856 CA340000869	616	V>A		No	ClinGen gnomAD
CA812295 rs745350125	619	G>S		No	ClinGen ExAC gnomAD
CA340001010 rs1265743877	622	T>M		No	ClinGen TOPMed gnomAD
rs1447541618 CA340001026	623	V>A		No	ClinGen gnomAD
rs1356278983 CA340001018	623	V>I		No	ClinGen gnomAD
rs771749077 CA812296	624	R>Q		No	ClinGen ExAC gnomAD
CA340001055 rs1570482815	625	V>G		No	ClinGen Ensembl
rs1224465661 CA340001042	625	V>I		No	ClinGen gnomAD
rs1284800093 CA340001064	626	S>N		No	ClinGen gnomAD
CA812299 rs769997975	629	P>L		No	ClinGen ExAC TOPMed gnomAD
CA340001131 rs769997975	629	P>R		No	ClinGen ExAC TOPMed gnomAD
CA812301 rs763125381	630	P>L		No	ClinGen ExAC gnomAD
TCGA novel	630	P>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA340002054 rs1235438684	632	A>T		No	ClinGen gnomAD
CA340002103 rs1380180843	633	D>A		No	ClinGen gnomAD
CA812305 rs767699823	633	D>N		No	ClinGen ExAC TOPMed gnomAD
rs17849101 CA812307 RCV000907090	635	R>C		No	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA812308 rs777362958	635	R>H		No	ClinGen ExAC gnomAD
CA812309 rs777362958	635	R>P		No	ClinGen ExAC gnomAD
TCGA novel	637	G>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA340002250 rs1332425527	637	G>S		No	ClinGen gnomAD
CA812311 rs369453577	638	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA812312 rs745583010	643	S>T		No	ClinGen ExAC gnomAD
CA812315 rs748539042 COSM1290203	644	V>M	haematopoietic_and_lymphoid_tissue [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
CA340002581 rs1199674135	646	Y>*		No	ClinGen TOPMed gnomAD
rs770367017 CA812316	647	E>K		No	ClinGen ExAC TOPMed gnomAD
rs1204546117 CA340002639	648	A>S		No	ClinGen gnomAD
CA812318 rs749626324	648	A>V		No	ClinGen ExAC gnomAD
CA340002681 rs1570484204	649	V>G		No	ClinGen Ensembl
TCGA novel	649	V>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1404810618 CA340002658	649	V>M		No	ClinGen TOPMed
CA812321 rs759809563	651	G>S		No	ClinGen ExAC gnomAD
CA812323 rs775642004	652	E>K		No	ClinGen ExAC TOPMed gnomAD
rs1410767912 CA340002800	653	D>G		No	ClinGen gnomAD
CA21652207 rs572442326	654	R>C		No	ClinGen 1000Genomes ExAC gnomAD
CA812325 rs764113767	654	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs572442326 CA812324	654	R>S		No	ClinGen 1000Genomes ExAC gnomAD
rs1331614439 CA340002848	655	G>E		No	ClinGen gnomAD
rs757114527 CA812327	655	G>R		No	ClinGen ExAC TOPMed gnomAD
rs1331614439 CA340002851	655	G>V		No	ClinGen gnomAD
rs985815285 CA340002857	656	R>G		No	ClinGen TOPMed gnomAD
CA340002873 rs1341268386	656	R>Q		No	ClinGen gnomAD
rs985815285 CA21652260	656	R>W		No	ClinGen TOPMed gnomAD
rs758076346 CA340002964	658	V>A		No	ClinGen ExAC gnomAD
rs758076346 CA812330	658	V>E		No	ClinGen ExAC gnomAD
CA340002943 rs1218826343	658	V>M		No	ClinGen TOPMed gnomAD
rs1215039768 CA340002972	659	V>M		No	ClinGen gnomAD
rs1254105738 CA340003023	661	G>S		No	ClinGen gnomAD
CA340003043 rs1451571570	662	I>V		No	ClinGen gnomAD
rs779393774 CA21652263	664	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA340003179 rs1253367699	664	R>H		No	ClinGen TOPMed
rs779393774 CA812331	664	R>S		No	ClinGen ExAC TOPMed gnomAD
CA21652265 rs951017386	665	E>Q		No	ClinGen Ensembl
CA21652290 rs865931555	668	S>R		No	ClinGen Ensembl
CA21652279 rs1054668971	668	S>T		No	ClinGen TOPMed
CA812333 rs17849102	670	D>N		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1463018567 CA340003507	672	V>L		No	ClinGen gnomAD
rs555258971 CA812335	675	E>K		No	ClinGen 1000Genomes ExAC gnomAD
rs1386119775 CA340003763	678	T>M		No	ClinGen gnomAD
CA340003776 rs1327972182	679	E>K		No	ClinGen gnomAD
rs1327972182 CA340003787	679	E>Q		No	ClinGen gnomAD
CA812336 rs771269220	681	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA21652301 rs912268666	681	R>W		No	ClinGen gnomAD
rs746021731 CA812338	682	V>L		No	ClinGen ExAC TOPMed gnomAD
rs1261619328 COSM1342893 COSM40517 CA340003977	683	W>*	large_intestine central_nervous_system [Cosmic]	No	ClinGen cosmic curated TOPMed
CA340004013 rs1223464697	684	V>G		No	ClinGen TOPMed
CA812340 rs775382791	685	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs144665293 CA812339	685	R>W		No	ClinGen ESP ExAC TOPMed gnomAD
CA812341 rs760786106	687	H>R		No	ClinGen ExAC gnomAD
rs201745531 CA340004175	689	D>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs201745531 CA812342	689	D>Y		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
TCGA novel	690	V>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA812344 rs761857102	690	V>M		No	ClinGen ExAC gnomAD
rs1456513017 CA340004229	691	G>A		No	ClinGen gnomAD
TCGA novel	691	G>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1387060597 CA340004236	692	P>A		No	ClinGen gnomAD
rs1297394345 CA340004248	693	G>S		No	ClinGen gnomAD
TCGA novel	694	P>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1416223281 CA340004285	695	E>K		No	ClinGen TOPMed gnomAD
rs1416223281 CA340004287	695	E>Q		No	ClinGen TOPMed gnomAD
rs894516328 CA21652374	697	S>N		No	ClinGen TOPMed
CA21652382 rs1006220911	698	P>L		No	ClinGen TOPMed gnomAD
CA340004407 rs1339361196	698	P>S		No	ClinGen gnomAD
rs1267826004 CA340004422	699	V>M		No	ClinGen gnomAD
CA340004481 rs1216281893	701	V>L		No	ClinGen gnomAD
rs1216281893 CA340004473	701	V>M		No	ClinGen gnomAD
rs1284292923 CA340004507	702	R>C		No	ClinGen gnomAD
CA340004511 rs1486879479	702	R>H		No	ClinGen gnomAD
CA340004582 rs1422069418	704	D>E		No	ClinGen TOPMed gnomAD
CA812348 rs766035780	704	D>H		No	ClinGen ExAC TOPMed gnomAD
CA21652400 rs766035780	704	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	705	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA340004682 rs1365430574	707	V>M		No	ClinGen gnomAD
CA812368 rs759127729	708	P>L		No	ClinGen ExAC gnomAD
rs757714695 CA21652948	710	G>R		No	ClinGen ExAC TOPMed gnomAD
CA812371 rs757714695	710	G>W		No	ClinGen ExAC TOPMed gnomAD
CA340004936 rs1308563374	713	R>Q		No	ClinGen TOPMed gnomAD
CA340005021 rs1266369144	717	V>G		No	ClinGen gnomAD
CA812375 rs780294143	717	V>L		No	ClinGen ExAC TOPMed gnomAD
rs1172354507 CA340005053	719	P>T		No	ClinGen gnomAD
CA340005090 rs1570496457	721	N>D		No	ClinGen Ensembl
TCGA novel	724	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1464586379 CA340005157	726	H>R		No	ClinGen gnomAD
rs1167949818 CA340005163	727	V>I		No	ClinGen gnomAD
CA340005177 rs1361334730	728	Y>H		No	ClinGen gnomAD
rs1352078594 CA340005182	728	Y>S		No	ClinGen gnomAD
rs769029754 CA812377	731	L>V		No	ClinGen ExAC gnomAD
CA812379 rs564141034	733	V>I		No	ClinGen 1000Genomes ExAC gnomAD
rs1384334912 CA340005288	735	S>N		No	ClinGen gnomAD
CA340005370 rs1404378647	740	Q>R		No	ClinGen TOPMed
TCGA novel	742	R>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA340005411 rs1202842302	743	G>R		No	ClinGen gnomAD
rs762860244 CA340005456	745	Q>H		No	ClinGen ExAC gnomAD
CA340005452 rs1216822839	745	Q>L		No	ClinGen gnomAD
CA340005470 rs1570497377	746	V>G		No	ClinGen Ensembl
rs770705836 CA812383	746	V>I		No	ClinGen ExAC gnomAD
rs774023984 CA812384	747	T>I		No	ClinGen ExAC gnomAD
CA812387 rs201048136 CA812388	749	V>L		No	ClinGen ExAC TOPMed gnomAD
rs201048136 CA812386	749	V>M		No	ClinGen ExAC TOPMed gnomAD
rs752038331 CA812389	750	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs149070360 CA812390	752	E>K		No	ClinGen ESP ExAC gnomAD
rs201114915 CA812392	755	E>K		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs751890381 CA812393	756	P>L		No	ClinGen ExAC TOPMed gnomAD
CA812394 rs755439618	757	R>C		No	ClinGen ExAC TOPMed gnomAD
CA340005618 rs1252295013	757	R>H		No	ClinGen TOPMed
CA340005643 rs1193658685	759	L>F		No	ClinGen TOPMed
CA812396 rs781530130	760	P>A		No	ClinGen ExAC gnomAD
CA812397 rs370187541	760	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA812395 rs781530130	760	P>S		No	ClinGen ExAC gnomAD
rs749186153 CA812399	761	I>M		No	ClinGen ExAC gnomAD
CA812398 rs373814583	761	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA812400 rs770807749	762	I>L		No	ClinGen ExAC TOPMed gnomAD
CA812401 rs770807749	762	I>V		No	ClinGen ExAC TOPMed gnomAD
CA340005748 rs1326333643	764	D>G		No	ClinGen TOPMed
rs377483278 CA812403	765	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs775119587 CA812405	766	M>L		No	ClinGen ExAC gnomAD
rs775119587 CA812404	766	M>V		No	ClinGen ExAC gnomAD
CA340005812 rs1319886203	767	L>V		No	ClinGen gnomAD
CA812406 rs763592362	768	A>G		No	ClinGen ExAC gnomAD
rs763465884 CA812408	769	E>K		No	ClinGen ExAC TOPMed gnomAD
CA340005894 rs752144648	770	A>G		No	ClinGen ExAC TOPMed gnomAD
rs766771427 CA812409	770	A>P		No	ClinGen ExAC TOPMed gnomAD
CA340005887 rs766771427	770	A>S		No	ClinGen ExAC TOPMed gnomAD
CA812410 rs752144648	770	A>V		No	ClinGen ExAC TOPMed gnomAD
CA812431 rs760137603	773	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA812430 rs774981977	773	R>W		No	ClinGen ExAC TOPMed gnomAD
CA340008554 rs1331891918	775	E>Q		No	ClinGen gnomAD
TCGA novel	776	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
COSM1687590 CA812432 rs767930658	777	S>F	skin [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
CA340008593 rs1312803474	778	E>K		No	ClinGen TOPMed gnomAD
CA340008594 rs1312803474	778	E>Q		No	ClinGen TOPMed gnomAD
CA340008619 rs1255710727	779	D>V		No	ClinGen TOPMed
CA340008630 rs1276421514	780	Y>H		No	ClinGen gnomAD
rs750523020 CA812457	781	E>K		No	ClinGen ExAC gnomAD
rs370538618 CA812458	782	T>A		No	ClinGen ESP ExAC TOPMed gnomAD
CA812459 rs779932793	782	T>I		No	ClinGen ExAC gnomAD
CA812460 rs751561553	783	T>I		No	ClinGen ExAC gnomAD
CA21656290 rs201466491	784	I>V		No	ClinGen 1000Genomes TOPMed
rs754712346 CA812461	785	S>G		No	ClinGen ExAC gnomAD
rs777222498 CA812462	785	S>R		No	ClinGen ExAC TOPMed gnomAD
rs747692299 CA812464	786	G>C		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	786	G>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA812463 rs747692299	786	G>S		No	ClinGen ExAC TOPMed gnomAD
rs1400192914 CA340008842	788	T>A		No	ClinGen gnomAD
CA812465 rs777372045	788	T>I		No	ClinGen ExAC TOPMed gnomAD
rs1400192914 CA340008844	788	T>P		No	ClinGen gnomAD
CA21656334 rs1043165223	789	P>A		No	ClinGen TOPMed gnomAD
rs1187179916 CA340008856	789	P>Q		No	ClinGen TOPMed gnomAD
rs1043165223 CA340008854	789	P>S		No	ClinGen TOPMed gnomAD
CA812467 rs746393821	790	E>D		No	ClinGen ExAC TOPMed gnomAD
CA340008909 rs1570552385	793	Y>S		No	ClinGen Ensembl
CA340008928 COSM1667506 rs1396097094	794	S>F	Variant assessed as Somatic; impact. skin [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed
rs572629636 CA812470	795	V>F		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
COSM1581560 rs572629636 CA812471	795	V>I	Variant assessed as Somatic; 0.0 impact. haematopoietic_and_lymphoid_tissue [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
rs1557827258 CA340008983	801	T>A		No	ClinGen Ensembl
rs200312726 CA812472	802	T>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
TCGA novel	805	D>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1216144298 CA340009023	807	A>S		No	ClinGen gnomAD
rs1425563157 CA340009029	808	R>C		No	ClinGen gnomAD
rs773461058 CA812474	808	R>H		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	809	S>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs763012613 CA812475 COSM4143990	810	K>R	thyroid [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
rs766501071 CA812476	811	P>H		No	ClinGen ExAC gnomAD
CA340009072 rs766501071	811	P>L		No	ClinGen ExAC gnomAD
CA812478 rs754943489	813	I>M		No	ClinGen ExAC TOPMed gnomAD
CA812477 rs751390769	813	I>T		No	ClinGen ExAC gnomAD
rs1455058213 CA340009104	814	V>I		No	ClinGen TOPMed
CA340009158 rs1420141737	818	G>D		No	ClinGen gnomAD
TCGA novel	820	V>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA812503 rs756975863	823	R>G		No	ClinGen ExAC gnomAD
rs565543436 CA812505	823	R>P		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs565543436 CA812504 COSM3805337	823	R>Q	Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
CA21656522 rs756975863	823	R>W		No	ClinGen ExAC gnomAD
rs1378330342 CA340009287	824	P>S		No	ClinGen gnomAD
CA812506 rs757885367	825	T>A		No	ClinGen ExAC gnomAD
rs912770030 CA21656525	826	M>V		No	ClinGen TOPMed
rs781719563 CA812507	830	T>A		No	ClinGen ExAC gnomAD
rs781719563 CA340009422	830	T>P		No	ClinGen ExAC gnomAD
rs367652888 CA812509	831	T>M		No	ClinGen ESP ExAC gnomAD
rs928654396 CA21656540	832	A>T		No	ClinGen TOPMed
CA812514 rs759632662	833	M>I		No	ClinGen ExAC gnomAD
CA812511 rs749468850	833	M>L		No	ClinGen ExAC gnomAD
CA812513 rs774490865	833	M>T		No	ClinGen ExAC TOPMed gnomAD
CA812512 rs749468850	833	M>V		No	ClinGen ExAC gnomAD
CA812515 rs772113752	835	T>S		No	ClinGen ExAC gnomAD
CA340009570 rs775486548	836	A>E		No	ClinGen ExAC TOPMed gnomAD
rs775486548 CA812516	836	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs763916687 CA812518	838	L>V		No	ClinGen ExAC gnomAD
rs1400453918 CA340009637	839	Q>R		No	ClinGen gnomAD
CA340009706 rs1465532015	842	P>S		No	ClinGen gnomAD
rs761748789 CA812520	844	K>R		No	ClinGen ExAC gnomAD
rs757908835 CA812523	849	E>G		No	ClinGen ExAC gnomAD
CA340009825 rs1343911174	849	E>K		No	ClinGen TOPMed gnomAD
CA340009854 rs1258769633	850	L>P		No	ClinGen gnomAD
CA812524 rs140594531	854	R>Q		No	ClinGen ESP ExAC TOPMed gnomAD
rs1317417745 CA340009908	854	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1308478616 CA340009920	856	Q>R		No	ClinGen TOPMed
CA340009936 rs1570555758	857	Y>D		No	ClinGen Ensembl
CA812526 rs756642128	858	C>S		No	ClinGen ExAC TOPMed gnomAD
CA812529 rs567638313	859	R>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
CA812528 rs567638313	859	R>P		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA21656675 rs567638313	859	R>Q		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA21656661 rs903248544	859	R>W		No	ClinGen TOPMed gnomAD
CA812531 rs779194364	860	A>P		No	ClinGen ExAC gnomAD
CA812530 rs779194364	860	A>T		No	ClinGen ExAC gnomAD
CA340010012 rs1168878964	861	D>E		No	ClinGen gnomAD
rs775437828 CA812533	861	D>N		No	ClinGen ExAC gnomAD
rs536681179 COSM909871 CA812534	862	E>K	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
rs144536559 CA812535	863	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs764998994 CA812538	864	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA812537 rs761693767	864	R>W		No	ClinGen ExAC TOPMed gnomAD
rs750031933 CA812539	866	N>D		No	ClinGen ExAC TOPMed gnomAD
rs1339921157 CA340010103	867	T>A		No	ClinGen gnomAD
CA812540 rs556307288	867	T>S		No	ClinGen 1000Genomes ExAC gnomAD
rs141782417 CA812541	868	I>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs199942675 CA21656766	869	D>E		No	ClinGen 1000Genomes
CA340010138 rs1253788010	869	D>G		No	ClinGen TOPMed
rs751089120 CA812542	869	D>N		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	869	D>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs778225680 CA812544	871	G>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs569510577 CA21656797	872	K>R		No	ClinGen Ensembl
CA812547 rs374488420	873	D>A		No	ClinGen ESP ExAC TOPMed gnomAD
rs374488420 CA812548	873	D>G		No	ClinGen ESP ExAC TOPMed gnomAD
CA812546 rs757630823	873	D>N		No	ClinGen ExAC TOPMed gnomAD
rs758580532 CA812549	874	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs780471380 CA812550	874	D>V		No	ClinGen ExAC TOPMed gnomAD
CA812552 rs768921761	875	Q>*		No	ClinGen ExAC gnomAD
rs776694646 CA812553	879	V>A		No	ClinGen ExAC gnomAD
rs748106240 CA812554	880	T>S		No	ClinGen ExAC gnomAD
rs143833153 CA812556	881	G>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA340010396 rs1380026703	883	H>Q		No	ClinGen gnomAD
rs762614069 CA812557	883	H>R		No	ClinGen ExAC TOPMed gnomAD
CA340010417 rs1396031076	884	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs1386301338 CA340010425	885	G>W		No	ClinGen TOPMed
rs1228814877 CA340010435	886	T>A		No	ClinGen TOPMed gnomAD
rs765928388 CA812558	887	T>I		No	ClinGen ExAC gnomAD
rs1570557821 CA340010449	888	Y>C		No	ClinGen Ensembl
CA340010466 rs1275615193	889	I>T		No	ClinGen Ensembl
rs759047074 CA812560	889	I>V		No	ClinGen ExAC gnomAD
CA340010492 rs767075536	891	R>G		No	ClinGen ExAC TOPMed gnomAD
rs199570599 CA812563	891	R>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA812562 rs199570599	891	R>Q		No	ClinGen ESP ExAC TOPMed gnomAD
CA812561 rs767075536 COSM426315	891	R>W	Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs975633818 CA21656871	894	A>D		No	ClinGen Ensembl
CA812564 rs765598646	894	A>T		No	ClinGen ExAC gnomAD
rs1186558185 CA340010590 COSM76120	896	N>K	ovary Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated NCI-TCGA TOPMed
CA21656881 rs374013593	897	R>G		No	ClinGen ESP ExAC TOPMed gnomAD
CA812566 rs149018733 COSM1639895	897	R>Q	stomach [Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD
CA812565 rs374013593	897	R>W		No	ClinGen ESP ExAC TOPMed gnomAD
CA340010603 rs1183508834	898	A>T		No	ClinGen gnomAD
rs780417996 CA812567	899	G>S		No	ClinGen ExAC gnomAD
CA340010639 rs747292574	900	L>M		No	ClinGen ExAC gnomAD
rs1215219655 CA340010648	900	L>W		No	ClinGen TOPMed
CA21656919 rs921513300	901	G>S		No	ClinGen gnomAD
rs1399141346 CA340010675	902	E>Q		No	ClinGen gnomAD
CA21656927 CA812571 rs146318210	904	F>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs143093912 CA812572	905	E>K		No	ClinGen ESP ExAC gnomAD
CA340010737 rs143093912	905	E>Q		No	ClinGen ESP ExAC gnomAD
rs1452022275 CA340010759	906	K>T		No	ClinGen gnomAD
CA812573 rs773247312	907	E>K		No	ClinGen ExAC gnomAD
TCGA novel	907	E>missing	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	910	T>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs770780891 CA812575	912	E>A		No	ClinGen ExAC gnomAD
CA21656973 rs138034295	912	E>K		No	ClinGen ESP
CA340010862 rs1570559024	913	D>A		No	ClinGen Ensembl
CA340010874 rs1327537333	914	L>M		No	ClinGen TOPMed
rs934709458 CA21656984	914	L>P		No	ClinGen Ensembl
CA340010935 rs1372400634	917	G>S		No	ClinGen gnomAD
CA340010948 rs1570559229	918	F>L		No	ClinGen Ensembl
rs1221716037 CA340010954	918	F>Y		No	ClinGen gnomAD
rs759204249 CA340010990	920	Q>P		No	ClinGen ExAC TOPMed gnomAD
rs759204249 CA812577	920	Q>R		No	ClinGen ExAC TOPMed gnomAD
rs201215550 CA21656994	923	H>R		No	ClinGen 1000Genomes gnomAD
CA340011075 rs1202491441	925	T>S		No	ClinGen gnomAD
CA812579 rs371676929	929	T>M		No	ClinGen ESP ExAC TOPMed gnomAD
CA340011221 rs1162437393	934	L>P		No	ClinGen TOPMed
rs765630159 CA812581	935	A>V		No	ClinGen ExAC gnomAD
rs758676706 CA812583	937	D>G		No	ClinGen ExAC gnomAD
rs200617199 CA812584	938	P>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1374746151 CA340011290	938	P>T		No	ClinGen TOPMed
rs200457473 CA21657016	941	L>V		No	ClinGen ExAC TOPMed gnomAD
RCV000953642 CA812587 rs144156070	942	A>V		No	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs368237069 CA340012470	945	N>K		No	ClinGen ESP ExAC TOPMed gnomAD
CA340012477 rs1439775308	946	G>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs372831256 CA812590	947	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
COSM267285 rs749309238 CA812591	947	R>H	large_intestine Variant assessed as Somatic; 4.621e-05 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed
rs749309238 CA812593	947	R>L		No	ClinGen ExAC TOPMed
rs770658279 CA812594	949	I>V		No	ClinGen ExAC TOPMed gnomAD
rs1319465451 CA340012549	950	S>G		No	ClinGen gnomAD
rs1319465451 CA340012554 COSM3735353	950	S>R	skin [Cosmic]	No	ClinGen cosmic curated gnomAD
rs377187728 CA812595	950	S>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA812597 rs531936522 COSM1687591	952	T>I	skin [Cosmic]	No	ClinGen cosmic curated 1000Genomes ExAC gnomAD
CA340012584 rs1570560625	952	T>P		No	ClinGen Ensembl
rs763045167 CA812599 COSM909873	953	V>M	endometrium Variant assessed as Somatic; 4.62e-05 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
CA340012632 rs1570560846	954	V>G		No	ClinGen Ensembl
CA812601 rs773533532	954	V>M		No	ClinGen ExAC gnomAD
CA21657135 rs975560273	955	F>L		No	ClinGen Ensembl
CA340012665 rs141556963	956	R>L		No	ClinGen ESP TOPMed
CA21657140 rs141556963	956	R>Q		No	ClinGen ESP TOPMed
rs967562018 CA21657145	957	D>H		No	ClinGen TOPMed gnomAD
CA812602 rs763519084	958	I>L		No	ClinGen ExAC TOPMed gnomAD
CA340012722 rs1168370988	959	N>I		No	ClinGen TOPMed gnomAD
CA340012720 rs1168370988	959	N>S		No	ClinGen TOPMed gnomAD
rs766805311 CA812603	962	Q>*		No	ClinGen ExAC gnomAD
rs1407965948 CA340012774	962	Q>R		No	ClinGen gnomAD
rs760025156 CA812605	963	E>A		No	ClinGen ExAC TOPMed gnomAD
CA812604 rs751990346	963	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	963	E>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1557830376 CA340012817	965	Q>K		No	ClinGen Ensembl
rs767813886 CA812606	968	T>M		No	ClinGen ExAC gnomAD
CA812608 rs559214265	969	T>A		No	ClinGen 1000Genomes ExAC gnomAD
rs1230582995 CA340012932	970	D>E		No	ClinGen gnomAD
rs150944733 CA812609	972	R>C		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs753655848 CA812610	972	R>H		No	ClinGen ExAC TOPMed gnomAD
rs753655848 CA340012954	972	R>L		No	ClinGen ExAC TOPMed gnomAD
CA812611 rs369570389	977	G>D		No	ClinGen ESP ExAC TOPMed gnomAD
rs778630314 CA812612	981	D>G		No	ClinGen ExAC gnomAD
TCGA novel	981	D>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs942033991 CA21657183	982	T>A		No	ClinGen TOPMed gnomAD
TCGA novel	982	T>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs771919313 CA812614	983	T>A		No	ClinGen ExAC TOPMed gnomAD
rs771919313 CA340013107	983	T>S		No	ClinGen ExAC TOPMed gnomAD
CA812616 rs150026558	985	D>H		No	ClinGen ESP ExAC TOPMed gnomAD
CA812617 rs150026558	985	D>N		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	985	D>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA812618 rs776232578	986	I>T		No	ClinGen ExAC gnomAD
rs763500218 CA812619	987	K>R		No	ClinGen ExAC gnomAD
CA340013186 COSM212227 rs1382248110	989	R>C	breast [Cosmic]	No	ClinGen cosmic curated gnomAD
CA812620 rs548061948	989	R>H	Variant assessed as Somatic; 4.62e-05 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
CA340013181 rs1382248110	989	R>S		No	ClinGen gnomAD
CA340013200 rs759978013	990	A>S		No	ClinGen ExAC TOPMed gnomAD
CA812622 rs759978013	990	A>T		No	ClinGen ExAC TOPMed gnomAD
rs1316424363 CA340013253	993	S>R		No	ClinGen gnomAD
rs767986292 CA812623	995	G>V		No	ClinGen ExAC gnomAD
CA340013313 rs142730107	996	S>F		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA812624 rs142730107	996	S>Y		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA21657266 rs926458641	997	G>V		No	ClinGen Ensembl
CA340013328 rs1336043622	998	P>A		No	ClinGen TOPMed
CA812625 rs760959754	1001	P>S		No	ClinGen ExAC gnomAD
rs1204814396 CA340013376	1002	S>G		No	ClinGen gnomAD
rs372819126 CA812627	1006	R>Q		No	ClinGen 1000Genomes ESP ExAC gnomAD
CA812626 rs764041935	1006	R>W		No	ClinGen ExAC TOPMed gnomAD
CA812629 rs765129553	1009	P>L		No	ClinGen ExAC gnomAD
CA21657301 rs890253672 COSM3400814	1009	P>S	central_nervous_system [Cosmic]	No	ClinGen cosmic curated TOPMed gnomAD
CA340013475 rs890253672	1009	P>T		No	ClinGen TOPMed gnomAD
rs758129822 CA340013484	1010	V>L		No	ClinGen ExAC TOPMed gnomAD
CA812631 rs758129822	1010	V>M		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	1015	A>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA340013626 rs1557832814	1015	A>T		No	ClinGen Ensembl
CA812663 rs776774997	1016	K>E		No	ClinGen ExAC gnomAD
CA812664 rs373189867	1016	K>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs1479176471 CA340013683	1019	R>G		No	ClinGen TOPMed gnomAD
CA812665 COSM1639896 rs376126555	1019	R>Q	stomach [Cosmic]	No	ClinGen cosmic curated ESP ExAC TOPMed gnomAD
CA340013685 rs1479176471	1019	R>W		No	ClinGen TOPMed gnomAD
CA812669 rs147874335	1021	A>E		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA340013711 rs1296789107	1021	A>T		No	ClinGen TOPMed gnomAD
COSM1321047 rs147874335 CA812668	1021	A>V	ovary [Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	1024	M>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs767435818 CA812671	1024	M>T		No	ClinGen ExAC TOPMed gnomAD
rs1236358043 CA340013777	1025	K>N		No	ClinGen gnomAD
rs752333602 CA812672	1026	T>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA21657931 rs752333602	1026	T>R		No	ClinGen ExAC TOPMed gnomAD
CA340013874 rs753377322	1033	E>K		No	ClinGen ExAC TOPMed gnomAD
rs753377322 CA812675	1033	E>Q		No	ClinGen ExAC TOPMed gnomAD
CA340013898 rs1203710565	1034	V>A		No	ClinGen TOPMed
rs1226668425 CA340013893	1034	V>F		No	ClinGen gnomAD
CA812677 rs780607373	1036	D>N		No	ClinGen ExAC gnomAD
rs932626438 CA21657975	1037	S>P		No	ClinGen Ensembl
CA812679 rs768996333	1038	Y>C		No	ClinGen ExAC TOPMed gnomAD
rs1489613514 CA340013929	1038	Y>N		No	ClinGen gnomAD
CA340013956 rs1428406780	1041	A>S		No	ClinGen gnomAD
CA340013961 rs1169040424	1041	A>V		No	ClinGen gnomAD
rs1387459525 CA340013976	1043	P>S		No	ClinGen gnomAD
rs996563431 CA21658286	1047	L>V		No	ClinGen TOPMed
CA812705 rs749482455	1049	N>H		No	ClinGen ExAC gnomAD
CA340014190 rs1336067113	1050	G>E	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA340014183 rs1470249056	1050	G>R		No	ClinGen gnomAD
rs774328700 CA812707	1051	Q>H		No	ClinGen ExAC TOPMed gnomAD
rs1226243678 CA340014250 COSM909875	1053	V>M	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed gnomAD
rs1570576124 CA340014291	1055	V>G		No	ClinGen Ensembl
CA812709 rs372260512	1055	V>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA340014280 rs372260512	1055	V>M		No	ClinGen ESP ExAC TOPMed gnomAD
rs775609904 CA812710	1056	D>V		No	ClinGen ExAC gnomAD
CA812713 rs776291761	1057	G>E		No	ClinGen ExAC TOPMed gnomAD
rs764039671 CA812712	1057	G>R		No	ClinGen ExAC gnomAD
CA812714 rs761400999	1059	S>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1570576425 CA340014375	1060	M>I		No	ClinGen Ensembl
CA340014357 rs1479762337	1060	M>V		No	ClinGen gnomAD
CA812718 rs562011415	1061	R>Q		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
COSM1602443 rs571838340 CA812716	1061	R>W	liver [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
CA812719 rs185189309	1062	K>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA21658317 rs937549257	1064	I>V		No	ClinGen TOPMed gnomAD
CA812722 rs749489783	1065	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA812724 rs138775864	1068	Q>R		No	ClinGen ESP ExAC gnomAD
rs1345537230 CA340014534	1071	T>A		No	ClinGen gnomAD
CA340014537 rs1222402946	1071	T>R		No	ClinGen gnomAD
rs201157421 CA340014540	1072	E>K		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA812725 rs201157421	1072	E>Q		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA340014543 rs1309209393	1072	E>V		No	ClinGen TOPMed
CA812726 rs772345902	1074	S>L		No	ClinGen ExAC gnomAD
CA812728 rs746959174	1076	V>E		No	ClinGen ExAC gnomAD
CA340014578 rs1269874113	1078	M>V		No	ClinGen gnomAD
CA812730 rs776311252	1080	R>C		No	ClinGen ExAC TOPMed gnomAD
CA340014596 COSM1263473 rs1169752499	1080	R>H	oesophagus [Cosmic]	No	ClinGen cosmic curated TOPMed
CA21658375 rs1004871676	1081	G>D		No	ClinGen Ensembl
CA812731 rs761716835	1082	S>R		No	ClinGen ExAC TOPMed gnomAD
CA812732 rs764765679	1083	S>G		No	ClinGen ExAC TOPMed gnomAD
rs1446354822 CA340014634	1086	G>A		No	ClinGen TOPMed gnomAD
CA812735 rs374873502	1094	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs1427598531 CA340014683	1094	R>H		No	ClinGen gnomAD
rs1427598531 CA340014685	1094	R>L		No	ClinGen gnomAD
rs374873502 CA340014681	1094	R>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs1365828057 CA340014697	1096	A>V		No	ClinGen gnomAD
CA21658428 rs1052391678	1098	D>A		No	ClinGen gnomAD
CA812736 rs369561113	1098	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	1098	D>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1270142418 CA340014726	1101	P>L		No	ClinGen gnomAD
rs1292713576 CA340014732	1102	H>Q		No	ClinGen gnomAD
CA21658450 rs908069420	1102	H>R		No	ClinGen TOPMed gnomAD
CA340014729 rs1340394688 COSM1296474	1102	H>Y	Variant assessed as Somatic; 0.0 impact. urinary_tract [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA gnomAD
rs756648293 CA812738	1104	P>L		No	ClinGen ExAC TOPMed gnomAD
CA21658493 rs556597635	1106	P>A		No	ClinGen TOPMed gnomAD
rs1040485073 CA21658495	1106	P>H		No	ClinGen TOPMed
CA340014767 rs1193744322	1108	S>F		No	ClinGen gnomAD
rs1241454644 CA340014768	1109	A>T		No	ClinGen TOPMed gnomAD
rs922030109 CA21658497	1110	Y>C		No	ClinGen TOPMed
CA812741 rs754133916	1111	I>V		No	ClinGen ExAC TOPMed gnomAD
rs1466581866 CA340014799	1113	D>G		No	ClinGen TOPMed
rs1470313594 CA340014807	1114	G>D		No	ClinGen gnomAD
CA812744 rs746151545	1114	G>S		No	ClinGen ExAC TOPMed gnomAD
rs758496561 CA812745	1115	R>C		No	ClinGen ExAC TOPMed gnomAD
rs780287442 CA812746	1115	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs372991117 COSM909877 CA812748	1117	D>N	endometrium Variant assessed as Somatic; 4.629e-05 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD
CA340014821 rs372991117	1117	D>Y		No	ClinGen ESP ExAC TOPMed gnomAD
rs147294972 CA812750	1120	M>L		No	ClinGen ESP ExAC gnomAD
rs147294972 CA812751	1120	M>V		No	ClinGen ESP ExAC gnomAD
CA340014847 rs1249672058	1121	P>S		No	ClinGen TOPMed
CA340014854 rs1316134423	1122	H>Y		No	ClinGen gnomAD
rs1052346675 CA340014860	1123	V>L		No	ClinGen TOPMed gnomAD
rs1052346675 CA21658549	1123	V>M		No	ClinGen TOPMed gnomAD
rs762596997 CA340014871	1124	Q>H		No	ClinGen ExAC gnomAD
rs144922906 CA812756	1127	S>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs754439849 CA812758	1128	L>F		No	ClinGen ExAC gnomAD
rs762075103 CA812759	1128	L>P		No	ClinGen ExAC TOPMed gnomAD
rs1433877718 CA340014908	1129	V>I		No	ClinGen gnomAD
CA340014972 rs1177703423	1131	W>R		No	ClinGen gnomAD
CA812785 rs754954516	1132	F>L		No	ClinGen ExAC gnomAD
CA21658897 rs751794621	1135	V>A		No	ClinGen TOPMed
rs1449609779 CA340015047	1137	V>A		No	ClinGen gnomAD
rs1300227430 CA340015041	1137	V>L		No	ClinGen gnomAD
CA340015040 rs1300227430	1137	V>M		No	ClinGen gnomAD
CA812790 rs749053302	1139	I>F		No	ClinGen ExAC gnomAD
CA812791 rs749053302	1139	I>V		No	ClinGen ExAC gnomAD
CA812792 CA340015082 rs778528006	1140	D>E		No	ClinGen ExAC gnomAD
rs367745532 CA812793	1141	R>C		No	ClinGen ESP ExAC TOPMed gnomAD
rs568722457 CA812794	1141	R>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs568722457 CA21658968	1141	R>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA812798 rs781399271	1144	G>E		No	ClinGen ExAC gnomAD
COSM3718377 CA812797 rs182011131	1144	G>R	upper_aerodigestive_tract [Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD
rs1293888921 CA340015125	1145	S>G		No	ClinGen TOPMed
rs368161767 CA812800	1146	M>V		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	1147	L>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA812801 rs774648724	1148	T>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1199546067 CA340015163	1148	T>S		No	ClinGen gnomAD
CA812803 rs767444947	1149	P>L		No	ClinGen ExAC gnomAD
rs935298487 CA21659050	1150	R>K		No	ClinGen TOPMed gnomAD
CA340015186 rs1373936203	1150	R>S		No	ClinGen gnomAD
CA340015188 rs1429515335	1151	W>R		No	ClinGen gnomAD
CA812804 rs752802502	1152	S>G		No	ClinGen ExAC gnomAD
CA812805 rs756190030	1153	T>I		No	ClinGen ExAC gnomAD
CA340015221 rs1405832871	1154	P>A		No	ClinGen gnomAD
rs764015900 CA812806	1154	P>L		No	ClinGen ExAC gnomAD
CA812810 rs745474278	1155	E>G		No	ClinGen ExAC gnomAD
rs199816949 CA812809	1155	E>K		No	ClinGen ESP ExAC TOPMed gnomAD
CA340015246 rs1427552012	1156	E>G		No	ClinGen TOPMed
rs1570582210 CA340015253	1157	L>M		No	ClinGen Ensembl
TCGA novel	1159	L>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA340015280 rs779610758	1159	L>P		No	ClinGen ExAC TOPMed gnomAD
rs779610758 CA812812	1159	L>Q		No	ClinGen ExAC TOPMed gnomAD
rs780748743 CA21659172	1160	D>N		No	ClinGen gnomAD
rs550783962 CA812814	1161	E>K		No	ClinGen 1000Genomes ExAC gnomAD
CA340016406 rs1183169145	1165	A>T		No	ClinGen gnomAD
CA812840 rs768685317	1166	I>M		No	ClinGen ExAC TOPMed gnomAD
CA812842 rs761933077	1167	E>D		No	ClinGen ExAC TOPMed gnomAD
CA812841 rs373597673	1167	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs373597673 CA340016428	1167	E>Q		No	ClinGen ESP ExAC TOPMed gnomAD
CA340016432 rs1209891475	1167	E>V		No	ClinGen gnomAD
rs765214291 CA340016463	1168	Q>H		No	ClinGen ExAC TOPMed gnomAD
CA812844 rs750382273	1169	G>D		No	ClinGen ExAC TOPMed gnomAD
CA812846 rs766088168	1170	G>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs540407495 CA812847	1171	E>K		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1469140370 CA340016521	1172	E>G		No	ClinGen TOPMed
CA340016534 rs754700311	1173	Q>*		No	ClinGen ExAC gnomAD
CA812850 rs754700311	1173	Q>E		No	ClinGen ExAC gnomAD
CA812853 rs1041522982	1173	Q>R		No	ClinGen TOPMed
COSM3671770 rs377569778 CA812857	1174	R>Q	prostate [Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD
CA812856 rs549143666	1174	R>W		No	ClinGen ExAC TOPMed gnomAD
rs200483026 CA812859	1175	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA812858 rs755754272	1175	R>W		No	ClinGen ExAC TOPMed gnomAD
rs772418794 CA812861	1176	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs368885602 CA812860	1176	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
rs202117609 CA812863	1177	R>Q		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA812862 rs369419270	1177	R>W		No	ClinGen ESP ExAC TOPMed gnomAD
rs140315523 CA812865	1178	R>Q		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA812864 rs768846692	1178	R>W		No	ClinGen ExAC TOPMed gnomAD
rs1309641384 CA340016626	1179	Q>R		No	ClinGen gnomAD
rs1315505195 CA340016656	1181	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1037410695 CA21660971	1182	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA812868 COSM27006 rs138093418	1182	R>H	kidney [Cosmic]	No	ClinGen cosmic curated ESP ExAC TOPMed gnomAD
CA812869 rs530770514	1183	L>V		No	ClinGen 1000Genomes ExAC gnomAD
CA812870 rs775642672	1184	K>R		No	ClinGen ExAC TOPMed gnomAD
CA812872 rs766148161	1185	P>L		No	ClinGen ExAC TOPMed gnomAD
CA812871 rs766148161	1185	P>Q		No	ClinGen ExAC TOPMed gnomAD
rs759442309 CA812873	1188	A>S		No	ClinGen ExAC TOPMed gnomAD
rs759442309 CA340016782	1188	A>T		No	ClinGen ExAC TOPMed gnomAD
CA812875 rs752458078	1191	L>M		No	ClinGen ExAC gnomAD
CA812876 rs755593552	1192	D>N		No	ClinGen ExAC TOPMed gnomAD
CA812877 rs763517386	1193	V>M		No	ClinGen ExAC TOPMed gnomAD
rs150503655 CA21661025	1194	L>P		No	ClinGen ESP TOPMed
CA812880 rs748552530	1195	P>L		No	ClinGen ExAC TOPMed gnomAD
CA812884 rs748370657	1199	T>I		No	ClinGen ExAC gnomAD
rs1292584776 CA340016964	1200	L>V		No	ClinGen gnomAD
rs1451115204 CA340016990	1202	D>N		No	ClinGen gnomAD
CA812886 rs200885607	1205	N>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA812888 rs770740453	1207	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA812887 rs368723795	1207	R>W		No	ClinGen ESP ExAC TOPMed gnomAD
CA812889 rs774497940	1208	G>D		No	ClinGen ExAC gnomAD
CA21661092 rs989434962	1208	G>S		No	ClinGen Ensembl
CA340017152 rs1460405185	1210	Y>H		No	ClinGen gnomAD
CA812893 rs376364770	1212	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA812891 rs201150809	1212	R>W		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1557839643 CA340017233	1214	L>M		No	ClinGen Ensembl
rs753268231 CA812895	1215	S>F		No	ClinGen ExAC gnomAD
rs566920391 CA812896	1216	P>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA340017288 rs1553209425	1217	D>G		No	ClinGen Ensembl
CA812898 rs200603784	1217	D>H		No	ClinGen 1000Genomes ExAC gnomAD
rs755264682 CA812899	1220	Y>H		No	ClinGen ExAC TOPMed gnomAD
CA812901 rs748351910	1224	V>M		No	ClinGen ExAC gnomAD
rs928460748 CA21661141	1225	L>F		No	ClinGen Ensembl
CA340017474 rs1286475973	1226	A>T		No	ClinGen gnomAD
CA340017493 rs1466179412	1227	S>P		No	ClinGen gnomAD
rs1209338659 CA340017582	1231	P>A		No	ClinGen gnomAD
CA21661143 rs984033281	1231	P>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs1209338659 CA340017584	1231	P>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs778093838 CA812903	1232	M>L		No	ClinGen ExAC gnomAD
CA812904 rs199504853	1232	M>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA812906 rs774375134	1233	D>E		No	ClinGen ExAC gnomAD
CA812905 rs771102511	1233	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
TCGA novel	1234	Q>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA21661473 rs928942520	1236	R>C		No	ClinGen TOPMed gnomAD
CA812933 rs772686657	1236	R>H		No	ClinGen ExAC TOPMed gnomAD
CA340017837 rs772686657	1236	R>L		No	ClinGen ExAC TOPMed gnomAD
CA340017824 rs928942520	1236	R>S		No	ClinGen TOPMed gnomAD
rs1307184836 CA340017844	1237	Y>H		No	ClinGen TOPMed gnomAD
CA812934 rs199960147	1238	A>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA812935 rs768005889	1239	S>P		No	ClinGen ExAC gnomAD
CA812936 rs753303584	1242	Y>*		No	ClinGen ExAC gnomAD
rs760891458 CA340017980	1243	S>L		No	ClinGen ExAC TOPMed gnomAD
rs760891458 CA812937	1243	S>W		No	ClinGen ExAC TOPMed gnomAD
rs1306249673 CA340018017	1244	D>E		No	ClinGen gnomAD
CA812941 rs371253686	1247	V>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs371253686 CA812940	1247	V>M		No	ClinGen ESP ExAC TOPMed gnomAD
CA812942 rs375842660	1248	V>F		No	ClinGen ESP ExAC gnomAD
CA812943 rs375842660	1248	V>I		No	ClinGen ESP ExAC gnomAD
rs779846237 CA812944	1249	Q>R		No	ClinGen ExAC gnomAD
CA812946 rs768291568	1252	P>L		No	ClinGen ExAC
CA812945 rs746966652	1252	P>S		No	ClinGen ExAC gnomAD
rs781060877 CA812947	1253	A>V		No	ClinGen ExAC gnomAD
CA812949 rs747982551	1254	Q>H		No	ClinGen ExAC gnomAD
rs769404453 CA812950	1255	Q>E		No	ClinGen ExAC TOPMed gnomAD
rs1165482795 CA340018267	1256	Q>H		No	ClinGen TOPMed
CA812951 rs146804143	1257	E>K		No	ClinGen ESP ExAC TOPMed gnomAD
CA812953 rs145421480	1259	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA812956 rs764318613	1261	M>I		No	ClinGen ExAC gnomAD
rs777034925 CA812957 COSM909878	1265	T>M	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA340018484 rs1351632915	1266	G>D		No	ClinGen gnomAD
CA812961 COSM909879 rs201841127	1268	V>M	Variant assessed as Somatic; 0.0001387 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
CA340018549 rs1570598703	1271	V>A		No	ClinGen Ensembl
rs1282776699 CA340018608	1275	I>V		No	ClinGen Ensembl
CA812966 rs754919062	1276	L>F		No	ClinGen ExAC TOPMed gnomAD
CA812965 rs754919062	1276	L>I		No	ClinGen ExAC TOPMed gnomAD
rs747931170 CA812967	1277	I>V		No	ClinGen ExAC TOPMed gnomAD
CA812969 rs146960105	1280	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA812972 rs773936534	1282	L>I		No	ClinGen ExAC TOPMed gnomAD
rs753964488 CA21661669	1282	L>P		No	ClinGen Ensembl
CA813000 rs773686451	1289	T>N		No	ClinGen ExAC gnomAD
rs763264668 CA813001	1290	H>R		No	ClinGen ExAC gnomAD
rs1448221458 CA340019116	1291	S>C		No	ClinGen TOPMed gnomAD
rs1448221458 CA340019117	1291	S>F		No	ClinGen TOPMed gnomAD
CA21663815 rs763328337	1292	P>L		No	ClinGen TOPMed
CA340019128 rs1253960522	1293	S>F		No	ClinGen TOPMed
CA340019136 rs1570624727	1295	K>E		No	ClinGen Ensembl
CA813006 rs752592428	1301	G>R		No	ClinGen ExAC gnomAD
rs760628972 CA813007	1301	G>V		No	ClinGen ExAC gnomAD
CA21663850 rs993036102	1306	L>F		No	ClinGen TOPMed
rs1049953768 CA21663852	1308	A>V		No	ClinGen TOPMed gnomAD
rs764069317 CA813008	1312	D>H		No	ClinGen ExAC TOPMed gnomAD
rs753601305 CA813009	1313	P>A		No	ClinGen ExAC gnomAD
CA340019282 rs113465093	1317	R>G		No	ClinGen TOPMed
CA813010 rs777629923	1317	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs113465093 CA21663876	1317	R>W		No	ClinGen TOPMed
CA340019287 rs1484052835	1318	R>K		No	ClinGen gnomAD
CA21663904 rs1044521354	1321	Y>C		No	ClinGen TOPMed gnomAD
CA21663920 rs551264881	1322	Q>E		No	ClinGen TOPMed gnomAD
CA340019323 rs1411223375	1323	T>N		No	ClinGen TOPMed
TCGA novel	1324	P>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1237499608 CA340020236	1326	M>I		No	ClinGen gnomAD
rs1189198619 CA340020232	1326	M>T		No	ClinGen TOPMed gnomAD
CA813054 rs765265238	1327	R>G		No	ClinGen ExAC gnomAD
rs1163354852 CA340020240	1327	R>Q		No	ClinGen TOPMed gnomAD
CA340020249 rs1414794847	1329	H>N		No	ClinGen TOPMed gnomAD
CA340020269 rs1458274555	1330	P>L		No	ClinGen gnomAD
TCGA novel	1330	P>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA813055 rs772848582	1332	I>V		No	ClinGen ExAC gnomAD
rs762905507 CA813056	1333	P>S		No	ClinGen ExAC gnomAD
rs145593130 CA21667782 COSM108155	1335	T>I	skin [Cosmic]	No	ClinGen cosmic curated Ensembl
rs771277235 CA21667793	1336	D>N		No	ClinGen gnomAD
CA340020338 rs771277235	1336	D>Y		No	ClinGen gnomAD
rs751268560 CA340020352	1337	L>V		No	ClinGen ExAC TOPMed gnomAD
rs371752134 CA813059	1338	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA21667817 rs773927069	1340	N>D		No	ClinGen Ensembl
CA813062 rs754321401	1340	N>S		No	ClinGen ExAC TOPMed gnomAD
rs754321401 CA813061	1340	N>T		No	ClinGen ExAC TOPMed gnomAD
rs1348295565 CA340020401	1341	I>V		No	ClinGen gnomAD
rs746215058 CA813064	1342	E>G		No	ClinGen ExAC gnomAD
CA813063 rs779515985	1342	E>K		No	ClinGen ExAC TOPMed gnomAD
rs369549174 CA813065	1343	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs761487819 CA813066	1343	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA21667867 rs761487819	1343	R>L		No	ClinGen ExAC TOPMed gnomAD
CA813068 rs202114940	1345	K>R		No	ClinGen 1000Genomes ExAC gnomAD
rs528728508 CA21667902	1347	N>S		No	ClinGen TOPMed gnomAD
CA813070 rs748296641	1348	D>H		No	ClinGen ExAC TOPMed gnomAD
rs748296641 CA21667932	1348	D>N		No	ClinGen ExAC TOPMed gnomAD
rs1401725517 CA340020522	1350	L>R		No	ClinGen gnomAD
rs769612296 CA813071	1351	K>E		No	ClinGen ExAC gnomAD
rs1220050094 CA340020529	1351	K>T		No	ClinGen TOPMed
TCGA novel	1354	Q>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs944539538 CA21667938	1355	E>A		No	ClinGen TOPMed
CA813072 rs773257469	1355	E>D		No	ClinGen ExAC gnomAD
rs762776569 CA813073	1356	Y>S		No	ClinGen ExAC gnomAD
CA340020606 rs1420797332	1357	E>K		No	ClinGen gnomAD
rs763667914 CA813097	1359	I>V		No	ClinGen ExAC gnomAD
rs763477204 CA813099	1360	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1206641795 CA340020906	1363	Q>P		No	ClinGen TOPMed
CA340020926 rs1339395530	1364	Q>L		No	ClinGen TOPMed
rs751913526 CA813101	1366	T>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA340020953 rs751913526	1366	T>R		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	1368	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1370341354 CA340020999	1369	N>S		No	ClinGen gnomAD
CA813102 rs755425568	1370	S>P		No	ClinGen ExAC
TCGA novel	1373	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA340021059 rs1203282758	1374	V>L		No	ClinGen TOPMed gnomAD
CA340021056 rs1203282758	1374	V>M		No	ClinGen TOPMed gnomAD
rs1165576828 CA340021130	1380	R>H		No	ClinGen TOPMed gnomAD
CA813103 rs781210446	1381	Y>C		No	ClinGen ExAC gnomAD
CA21674070 rs886198606	1381	Y>D		No	ClinGen gnomAD
rs752966262 CA21674073	1382	A>G		No	ClinGen ExAC TOPMed gnomAD
rs752966262 COSM909882 CA813104	1382	A>V	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA813108 rs148741898	1386	A>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs148741898 CA813109	1386	A>T		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	1388	D>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs760409112 CA813113	1389	H>D		No	ClinGen ExAC gnomAD
rs1210951527 CA340021257	1391	R>*		No	ClinGen gnomAD
rs1210951527 CA340021255	1391	R>G		No	ClinGen gnomAD
CA813114 rs768005633	1392	V>I		No	ClinGen ExAC gnomAD
rs776101253 CA813115	1393	I>T		No	ClinGen ExAC TOPMed gnomAD
CA813116 rs761375386	1395	T>I		No	ClinGen ExAC TOPMed gnomAD
rs1417036459 CA340021345	1398	D>N		No	ClinGen gnomAD
rs895328726	1399	G>=	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs761012325 CA813141	1399	G>D		No	ClinGen ExAC gnomAD
CA340021362 rs1459855311	1399	G>S		No	ClinGen TOPMed gnomAD
rs764399239 CA813142	1400	V>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs202116615 CA813145	1402	G>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA813148 rs758321458	1404	D>A		No	ClinGen ExAC gnomAD
rs758321458 CA813147	1404	D>G		No	ClinGen ExAC gnomAD
CA340021507 rs1249085092	1407	N>S		No	ClinGen TOPMed
CA21674491 rs930278268	1409	N>D		No	ClinGen Ensembl
rs1427091924 CA340021579	1412	D>N		No	ClinGen gnomAD
rs754775343 CA813150	1414	Y>C		No	ClinGen ExAC gnomAD
rs780769007 CA813151	1415	R>C		No	ClinGen ExAC gnomAD
rs370637531 CA813152 COSM909883	1415	R>H	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD
rs1431134339 CA340021628	1416	K>E		No	ClinGen gnomAD
rs1431134339 CA340021631	1416	K>Q		No	ClinGen gnomAD
rs1337100027 CA340021678	1419	A>T		No	ClinGen gnomAD
rs1328990399 CA340021722	1421	I>V		No	ClinGen gnomAD
CA340021738 rs1310657329	1422	A>T		No	ClinGen TOPMed
CA813155 rs748798640	1423	T>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1322347994 CA340021787	1424	Q>P		No	ClinGen TOPMed
CA340021850 rs1557869652	1428	P>S		No	ClinGen Ensembl
CA340021918 rs1383913294	1431	M>V		No	ClinGen TOPMed
rs776942329 CA813160	1433	D>N		No	ClinGen ExAC TOPMed gnomAD
CA21674576 rs641351	1436	R>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA340022167 rs1202367134	1442	R>C		No	ClinGen gnomAD
CA813163 rs367870850	1442	R>H		No	ClinGen ExAC gnomAD
CA340022188 rs1192576595	1443	T>M		No	ClinGen gnomAD
rs1167972950 CA340022207	1444	A>D		No	ClinGen gnomAD
rs751468520 CA813166	1444	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA340022218 rs1408645384	1445	T>S		No	ClinGen TOPMed gnomAD
rs1167542100 CA340022256	1446	V>G		No	ClinGen gnomAD
CA340022271 rs1395607317	1447	V>A		No	ClinGen TOPMed gnomAD
CA813168 rs535518899	1448	M>T		No	ClinGen 1000Genomes ExAC gnomAD
rs549116245 CA813170	1451	R>Q		No	ClinGen 1000Genomes ExAC gnomAD
COSM1222636 CA813169 rs367752429	1451	R>W	large_intestine [Cosmic]	No	ClinGen cosmic curated ESP ExAC TOPMed gnomAD
CA340022356 rs1570719071	1453	E>G		No	ClinGen Ensembl
TCGA novel	1454	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1570719121 CA340022374	1454	E>G		No	ClinGen Ensembl
rs1570719151 CA340022381	1455	K>E		No	ClinGen Ensembl
CA340022398 rs1570719182	1456	S>A		No	ClinGen Ensembl
rs1212688237	1457	R>=	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
CA340022409 rs1570719227	1457	R>W		No	ClinGen Ensembl
rs1257687543 CA340023750	1458	V>A		No	ClinGen gnomAD
rs1212390431 CA340023742	1458	V>I		No	ClinGen gnomAD
TCGA novel	1460	C>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA21675236 rs903062795	1462	Q>E		No	ClinGen TOPMed gnomAD
rs778315843 CA813193	1467	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs745409381 CA813194	1467	R>H		No	ClinGen ExAC TOPMed gnomAD
rs1470736677 CA340023844	1468	G>C		No	ClinGen gnomAD
CA813195 rs769260975	1469	T>A		No	ClinGen ExAC gnomAD
rs781778248 CA813196	1469	T>I		No	ClinGen ExAC
rs1416435157 CA340023854	1470	E>K		No	ClinGen TOPMed gnomAD
rs1313551565 CA340023866	1471	T>S		No	ClinGen TOPMed gnomAD
CA340023879 rs1374926406	1473	G>D		No	ClinGen gnomAD
CA340023901 rs1570727242	1476	Q>H		No	ClinGen Ensembl
CA21675295 rs1012660995	1477	V>M		No	ClinGen TOPMed gnomAD
rs763118237 CA813200	1478	T>I		No	ClinGen ExAC TOPMed gnomAD
rs1022695131 CA21675314	1480	L>S		No	ClinGen TOPMed
CA813203 rs146964251	1481	D>H		No	ClinGen ESP ExAC
CA340023934 rs1459599287	1482	T>K		No	ClinGen Ensembl
CA21675319 rs775410354	1483	V>A		No	ClinGen ExAC gnomAD
CA813205 rs775410354	1483	V>G		No	ClinGen ExAC gnomAD
TCGA novel	1483	V>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1389018689 CA340023943	1484	E>Q		No	ClinGen TOPMed
rs1280346162 CA340023953	1485	L>R		No	ClinGen gnomAD
CA813206 rs760404112	1486	A>S		No	ClinGen ExAC gnomAD
CA813208 rs371587895	1488	Y>H		No	ClinGen ESP ExAC TOPMed gnomAD
CA813209 rs756825445	1489	T>A		No	ClinGen ExAC gnomAD
CA813210 rs764987244	1489	T>S		No	ClinGen ExAC gnomAD
rs749935647 COSM909885 CA813211	1491	R>C	Variant assessed as Somatic; 0.0 impact. large_intestine endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
rs375234489 COSM3400816 CA813212	1491	R>H	Variant assessed as Somatic; 0.0 impact. central_nervous_system [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD
rs202030226 CA813215	1494	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
CA340024006 rs1398514141	1495	L>F		No	ClinGen gnomAD
CA340024007 rs1398514141	1495	L>V		No	ClinGen gnomAD
rs1391964552 CA340024013	1496	H>Y		No	ClinGen gnomAD
rs1165369421 CA340024035	1498	S>R		No	ClinGen gnomAD
CA813240 rs142031392	1498	S>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA340024046 rs1290285355	1499	G>A		No	ClinGen TOPMed gnomAD
rs776693106 CA813243	1501	S>R		No	ClinGen ExAC
rs1381131887 CA340024057	1501	S>T		No	ClinGen gnomAD
rs761445525 CA813244	1504	R>C		No	ClinGen ExAC TOPMed gnomAD
CA813245 rs769736949	1504	R>H		No	ClinGen ExAC TOPMed gnomAD
rs190997680 CA813247	1505	E>K		No	ClinGen 1000Genomes ExAC gnomAD
RCV000912168 CA813248 rs17849118	1506	L>V		No	ClinGen ClinVar 1000Genomes ExAC TOPMed dbSNP gnomAD
rs1218164234 CA340024094	1507	R>C		No	ClinGen TOPMed gnomAD
CA21675730 rs1028882041 COSM909886	1507	R>H	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed gnomAD
rs1176281524 CA340024124	1511	F>C		No	ClinGen TOPMed
CA813250 rs759154108	1511	F>L		No	ClinGen ExAC TOPMed gnomAD
rs1476106910 CA340024162	1516	D>G		No	ClinGen gnomAD
rs1032025108 CA21675750	1517	H>R		No	ClinGen TOPMed
rs113456929 CA813253	1518	G>E		No	ClinGen ExAC TOPMed gnomAD
CA21675760 rs917133176	1520	P>A		No	ClinGen TOPMed
TCGA novel	1520	P>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA21675762 rs956429904	1525	P>A		No	ClinGen Ensembl
rs750825052 CA813255	1525	P>L		No	ClinGen ExAC gnomAD
CA813257 rs758595390	1528	A>D		No	ClinGen ExAC gnomAD
CA813256 rs758595390	1528	A>V		No	ClinGen ExAC gnomAD
rs70937045 CA813259	1531	R>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs70937045 CA813258	1531	R>Q		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA813262 rs755881493	1532	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA813261 rs748151594	1532	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs773121796 CA813263	1534	K>E		No	ClinGen ExAC gnomAD
rs762901411 CA340024269	1535	A>P		No	ClinGen ExAC gnomAD
CA813264 rs762901411	1535	A>T		No	ClinGen ExAC gnomAD
rs1237155038 CA340024277	1536	C>Y		No	ClinGen gnomAD
CA340024287 rs774058164 CA813266	1537	N>K		No	ClinGen ExAC TOPMed gnomAD
CA813265 rs770704706	1537	N>S		No	ClinGen ExAC TOPMed gnomAD
CA340024285 rs770704706	1537	N>T		No	ClinGen ExAC TOPMed gnomAD
rs758914545 CA813267	1539	L>V		No	ClinGen ExAC gnomAD
rs754258723 CA813269 COSM1667508	1541	A>T	large_intestine [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
CA340024311 rs1418092772	1542	G>R		No	ClinGen gnomAD
rs1454942387 CA340024325	1544	M>L		No	ClinGen TOPMed
rs563305665 CA813270	1544	M>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA340024331 rs1434767385	1545	V>M		No	ClinGen gnomAD
rs1172532472 CA340024338	1546	V>L		No	ClinGen gnomAD
rs868712206 CA21675857	1548	C>*		No	ClinGen gnomAD
rs767692370	1549	S>=	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
rs767692370 CA340024376	1549	S>R		No	ClinGen ExAC TOPMed gnomAD
rs756268896 CA340024380	1550	A>E		No	ClinGen ExAC TOPMed gnomAD
CA813297 rs752821972	1550	A>T		No	ClinGen ExAC TOPMed gnomAD
rs756268896 CA813298	1550	A>V		No	ClinGen ExAC TOPMed gnomAD
rs917715521 CA21676115	1552	V>A		No	ClinGen TOPMed
rs370996086 CA340024389	1552	V>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs370996086 CA813300	1552	V>M		No	ClinGen ESP ExAC TOPMed gnomAD
rs756962072 CA813301	1554	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs778737593 CA813302	1554	R>H		No	ClinGen ExAC TOPMed gnomAD
CA21676129 rs796130608	1555	T>A		No	ClinGen Ensembl
CA813303 rs745698006	1556	G>S		No	ClinGen ExAC TOPMed gnomAD
CA340024432 rs1216731645	1559	I>S		No	ClinGen gnomAD
CA813304 rs548137409	1559	I>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
COSM1667509 CA813305 rs545781120	1560	V>M	large_intestine [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
rs766848150 CA813310	1564	M>T		No	ClinGen ExAC gnomAD
rs763422012 CA813309	1564	M>V		No	ClinGen ExAC TOPMed gnomAD
CA813311 rs139472475	1567	R>Q		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA340024483 rs1273214223	1567	R>W		No	ClinGen TOPMed
CA813312 rs759888484	1568	M>V		No	ClinGen ExAC gnomAD
CA813313 rs767714096	1569	K>N		No	ClinGen ExAC TOPMed gnomAD
rs908518826 CA21676177	1571	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
rs1430627272 CA340024517	1572	K>E		No	ClinGen TOPMed
CA813314 rs752983554	1573	T>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA340024541 rs1317650582	1575	D>E		No	ClinGen TOPMed gnomAD
CA813316 rs374607021	1575	D>N		No	ClinGen ESP ExAC gnomAD
CA21676200 rs901266646	1576	I>M		No	ClinGen Ensembl
rs754009897 CA813317	1577	Y>C		No	ClinGen ExAC gnomAD
TCGA novel	1578	G>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA340024555 rs1398022225	1578	G>S		No	ClinGen gnomAD
CA813319 rs778771796	1580	V>A		No	ClinGen ExAC gnomAD
CA340024569 rs1557875012	1580	V>M		No	ClinGen Ensembl
rs779621604 CA813322	1583	M>I		No	ClinGen ExAC gnomAD
CA813321 rs758129076	1583	M>T		No	ClinGen ExAC gnomAD
CA813320 rs745670160	1583	M>V		No	ClinGen ExAC gnomAD
CA340024595 rs746682490	1584	R>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
COSM426317 rs1302070237 CA340024598	1584	R>Q	large_intestine Variant assessed as Somatic; impact. breast [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated NCI-TCGA gnomAD
rs768112017 CA813324	1585	S>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1185864439 CA340024649	1590	M>I		No	ClinGen gnomAD
CA813326 rs747718453	1590	M>V		No	ClinGen ExAC gnomAD
CA813327 rs377575574	1593	T>M		No	ClinGen ESP ExAC TOPMed gnomAD
rs1158238606 CA340024723	1595	D>N		No	ClinGen gnomAD
rs772345080 CA813330	1598	V>M		No	ClinGen ExAC TOPMed gnomAD
CA340024824 rs1395449668	1600	I>L		No	ClinGen gnomAD
CA340024833 rs1239648530	1600	I>T		No	ClinGen gnomAD
CA813331 rs371076941	1601	H>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA813332 rs760947139	1602	E>A		No	ClinGen ExAC gnomAD
CA813334 rs558223872	1603	A>S		No	ClinGen 1000Genomes ExAC gnomAD
rs373838949 CA813335	1603	A>V		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	1606	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA340024958 rs1344845933	1609	T>A		No	ClinGen gnomAD
CA813339 rs145211050	1609	T>M		No	ClinGen 1000Genomes ExAC gnomAD
rs780893841 CA813342	1610	C>Y		No	ClinGen ExAC
rs779426523 CA813346	1611	G>D		No	ClinGen ExAC gnomAD
rs200975835 CA813345	1611	G>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs779426523 TCGA novel CA340025005 RCV000791076	1611	G>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen ClinVar NCI-TCGA ExAC dbSNP gnomAD
CA813348 rs772747132	1614	E>Q		No	ClinGen ExAC TOPMed gnomAD
CA340025053 rs1570737818	1615	V>G		No	ClinGen Ensembl
rs775973893 CA813349	1617	A>V		No	ClinGen ExAC gnomAD
rs557123403 CA21676365	1618	R>C		No	ClinGen 1000Genomes TOPMed gnomAD
rs761178241 CA813350	1618	R>H		No	ClinGen ExAC TOPMed gnomAD
rs1330495069 CA340025096	1619	N>S		No	ClinGen TOPMed gnomAD
CA813352 rs202169828	1619	N>Y		No	ClinGen ESP ExAC TOPMed gnomAD
rs1163327417 CA340025130	1621	Y>C		No	ClinGen TOPMed gnomAD
CA813354 rs142117073	1621	Y>H		No	ClinGen ESP ExAC TOPMed gnomAD
rs1163327417 CA340025126	1621	Y>S		No	ClinGen TOPMed gnomAD
rs1303429374 CA340025140	1622	A>T		No	ClinGen gnomAD
CA813355 rs750332454	1623	H>Y		No	ClinGen ExAC gnomAD
CA813356 rs762765550	1625	Q>R		No	ClinGen ExAC gnomAD
CA813358 rs150085995	1628	G>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs1256630824 CA340025262	1629	Q>H		No	ClinGen gnomAD
rs1214567224 CA340025269	1630	V>A		No	ClinGen gnomAD
rs754777001 CA813359	1630	V>M		No	ClinGen ExAC gnomAD
rs752315680 CA813361	1631	P>S		No	ClinGen ExAC TOPMed gnomAD
CA813363 rs777117732	1633	G>E		No	ClinGen ExAC gnomAD
rs748877164 CA813364	1634	E>K		No	ClinGen ExAC gnomAD
CA340025336 rs1557876101	1635	S>R		No	ClinGen Ensembl
CA813365 rs758958686	1635	S>R		No	ClinGen ExAC gnomAD
CA813366 rs565355095	1636	V>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
COSM1581562 CA340025354 rs1397867455	1636	V>M	haematopoietic_and_lymphoid_tissue [Cosmic]	No	ClinGen cosmic curated TOPMed gnomAD
CA340025383 rs1389621772	1637	T>S		No	ClinGen gnomAD
CA813369 rs541451200	1638	A>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs541451200 CA813370	1638	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
rs1327523720 CA340025394	1638	A>V		No	ClinGen gnomAD
TCGA novel	1642	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1570739191 CA340025495	1644	K>M		No	ClinGen Ensembl
rs759439345 CA813394	1648	S>N		No	ClinGen ExAC gnomAD
rs767540594 CA813395	1650	K>R		No	ClinGen ExAC TOPMed gnomAD
CA813396 rs775132901	1651	A>S		No	ClinGen ExAC gnomAD
CA813397 rs775132901	1651	A>T		No	ClinGen ExAC gnomAD
CA21676718 rs532554718	1651	A>V		No	ClinGen 1000Genomes
rs1377458062 CA340025673	1652	H>Q		No	ClinGen TOPMed gnomAD
CA813398 rs763586039	1653	T>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs763586039 CA813399	1653	T>R		No	ClinGen ExAC TOPMed gnomAD
CA813402 rs749990734	1655	R>C		No	ClinGen ExAC TOPMed gnomAD
CA340025706 rs749990734	1655	R>G		No	ClinGen ExAC TOPMed gnomAD
rs755516127 CA813403	1655	R>H		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	1656	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1349886664 CA340025769	1658	S>T		No	ClinGen gnomAD
rs1016222559 COSM215589 CA21676793	1659	A>T	central_nervous_system [Cosmic]	No	ClinGen cosmic curated gnomAD
CA340025814 rs777812290	1660	N>I		No	ClinGen ExAC gnomAD
CA813407 rs777812290	1660	N>S		No	ClinGen ExAC gnomAD
rs565463212 CA340025829	1662	P>A		No	ClinGen 1000Genomes ExAC gnomAD
CA813408 rs565463212	1662	P>S		No	ClinGen 1000Genomes ExAC gnomAD
CA813409 rs771183252	1663	C>Y		No	ClinGen ExAC TOPMed gnomAD
rs1438768947 CA340025874	1665	K>T		No	ClinGen gnomAD
CA340025894 rs1570741869	1666	F>S		No	ClinGen Ensembl
CA813410 rs534381986	1668	N>S		No	ClinGen 1000Genomes ExAC gnomAD
CA813411 COSM909888 rs746007326	1669	R>Q	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
CA340025968 rs771897426	1671	V>E		No	ClinGen ExAC TOPMed gnomAD
rs771897426 CA813412	1671	V>G		No	ClinGen ExAC TOPMed gnomAD
CA813413 rs775500719	1672	N>D		No	ClinGen ExAC gnomAD
CA340026068 rs1463828635	1677	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1570742184 CA340026100	1679	T>P		No	ClinGen Ensembl
rs1444849774 CA340026122	1680	R>H		No	ClinGen TOPMed gnomAD
rs776380044 CA813416	1687	R>C		No	ClinGen ExAC gnomAD
rs1387514159 CA340026221	1687	R>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA340026243 rs1219699868	1689	V>M		No	ClinGen gnomAD
rs1188744998 CA340026292	1692	S>T		No	ClinGen TOPMed
CA340026336 rs1258470133	1694	Y>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1570742730 CA340026371	1696	N>S		No	ClinGen Ensembl
TCGA novel	1698	S>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA340026467 rs771181177	1702	G>A		No	ClinGen gnomAD
CA21676918 rs771181177	1702	G>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs139706869 CA813419	1702	G>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs1287074551 CA340026563	1706	Q>R		No	ClinGen gnomAD
rs1205474230 CA340026580	1708	A>V		No	ClinGen TOPMed
rs751071796 CA813444	1709	Y>C		No	ClinGen ExAC gnomAD
CA813446 rs764644238	1710	I>L		No	ClinGen ExAC gnomAD
rs1410487785 CA340026631	1717	A>T		No	ClinGen gnomAD
CA340026657 rs1557878360	1720	T>I		No	ClinGen Ensembl
CA813452 rs780147204 COSM909889	1721	E>K	oesophagus large_intestine endometrium Variant assessed as Somatic; 4.619e-05 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs1376549439 CA340026670	1722	D>G		No	ClinGen TOPMed
TCGA novel	1723	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1338025567 CA340026683	1724	W>R		No	ClinGen TOPMed
CA813453 rs747103988	1725	R>C		No	ClinGen ExAC gnomAD
CA813454 rs754926878	1725	R>H		No	ClinGen ExAC gnomAD
CA813455 rs781342226	1726	M>I		No	ClinGen ExAC gnomAD
rs769736790 CA813457	1728	W>R		No	ClinGen ExAC gnomAD
rs1471237893 CA340026717	1729	E>Q		No	ClinGen TOPMed
rs772962387 CA813458	1730	H>R		No	ClinGen ExAC TOPMed gnomAD
CA813460 rs142050471	1731	N>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA340026759 rs1240227296	1735	I>T		No	ClinGen gnomAD
rs773899805 CA813461	1735	I>V		No	ClinGen ExAC gnomAD
CA813462 rs759036059	1736	V>I		No	ClinGen ExAC gnomAD
TCGA novel	1737	M>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA813463 rs764519639	1739	T>A		No	ClinGen ExAC TOPMed gnomAD
CA340026788 rs1442172384	1740	K>E		No	ClinGen gnomAD
rs1185928664 CA340026790	1740	K>R		No	ClinGen gnomAD
CA813467 rs750789308	1742	R>Q		No	ClinGen ExAC gnomAD
CA813466 rs765620781	1742	R>W		No	ClinGen ExAC TOPMed
CA340026817 rs1178019713	1744	M>I		No	ClinGen gnomAD
rs1440607876 CA340026824	1745	G>A		No	ClinGen TOPMed
TCGA novel	1746	R>=	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA340027760 rs1450905649	1750	H>Q		No	ClinGen TOPMed gnomAD
CA340027823 rs1570750658	1754	P>R		No	ClinGen Ensembl
CA340027832 rs1478012102	1755	A>E		No	ClinGen gnomAD
CA340027827 rs1265297751	1755	A>T		No	ClinGen gnomAD
rs757017636 CA340027858	1757	R>C		No	ClinGen ExAC gnomAD
rs757017636 CA813495	1757	R>G		No	ClinGen ExAC gnomAD
COSM284381 rs372799990 CA813496	1757	R>H	Variant assessed as Somatic; 0.0 impact. large_intestine endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD
CA813497 rs745550474	1758	S>P		No	ClinGen ExAC gnomAD
CA813498 rs771751666	1759	A>V		No	ClinGen ExAC gnomAD
rs1385558867 CA340027897	1760	R>C		No	ClinGen gnomAD
CA813499 rs779513130	1760	R>H		No	ClinGen ExAC TOPMed gnomAD
CA340027906 rs779513130	1760	R>L		No	ClinGen ExAC TOPMed gnomAD
rs1223441079 CA340027983	1763	Y>F		No	ClinGen TOPMed gnomAD
CA340028029 rs1276775648	1765	V>I		No	ClinGen gnomAD
rs1323663408 CA340028052	1766	V>A		No	ClinGen gnomAD
rs770277923 CA813501	1767	D>A		No	ClinGen ExAC gnomAD
rs773594682 CA813502	1768	P>L		No	ClinGen ExAC TOPMed gnomAD
CA813503 rs763330721	1770	A>T		No	ClinGen ExAC gnomAD
rs1430783133 CA340028128	1770	A>V		No	ClinGen TOPMed
CA813506 rs759814948	1772	Y>F		No	ClinGen ExAC gnomAD
CA813507 rs767910194	1773	N>S		No	ClinGen ExAC gnomAD
CA21677447 rs201747944	1774	M>V		No	ClinGen TOPMed gnomAD
CA21677451 rs913340844	1775	P>L		No	ClinGen gnomAD
rs752820297 CA813508	1775	P>S		No	ClinGen ExAC TOPMed gnomAD
rs752820297 CA340028274	1775	P>T		No	ClinGen ExAC TOPMed gnomAD
rs1422196179 CA340028330	1776	Q>H		No	ClinGen gnomAD
CA813509 rs151136180	1780	R>H		No	ClinGen ESP ExAC TOPMed gnomAD
CA813511 rs151136180	1780	R>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs200155899 CA21677483	1781	E>G		No	ClinGen 1000Genomes
rs201633718 CA21677487	1783	K>R		No	ClinGen 1000Genomes
CA21677488 rs201039893	1785	T>A		No	ClinGen 1000Genomes gnomAD
CA340028517 rs1419632455	1785	T>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA340028547 rs1557880340	1786	D>V		No	ClinGen Ensembl
CA813513 rs746786262	1788	R>W		No	ClinGen ExAC TOPMed gnomAD
CA21677789 COSM3805343 COSM3805341 rs953278964	1790	G>R	Variant assessed as Somatic; impact. breast [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed
rs1427661601 CA340028750	1791	Q>H		No	ClinGen gnomAD
CA813549 rs768967831	1796	R>L		No	ClinGen ExAC gnomAD
CA340028827 rs768967831	1796	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs747165352 CA813548	1796	R>W		No	ClinGen ExAC gnomAD
CA340029051 rs1369562264	1807	G>V		No	ClinGen gnomAD
CA340029067 rs1570755803	1808	V>G		No	ClinGen Ensembl
rs762685023 CA813554	1808	V>M		No	ClinGen ExAC gnomAD
rs1220283248 CA340029074	1809	P>L		No	ClinGen TOPMed gnomAD
rs1370427192 CA340029098	1811	T>I		No	ClinGen TOPMed gnomAD
CA340029112 rs1201742137	1812	G>D		No	ClinGen gnomAD
CA340029142 rs1220801019	1813	E>D		No	ClinGen TOPMed
CA340029150 rs1309029917	1814	G>E		No	ClinGen gnomAD
rs1308023685 CA340029194	1816	I>V		No	ClinGen TOPMed
rs1191150782 CA340029255	1819	I>T		No	ClinGen gnomAD
rs752086534 CA813559	1820	G>W		No	ClinGen ExAC gnomAD
CA340029288 rs1171906145	1821	Q>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1570756284 CA340029300	1822	V>G		No	ClinGen Ensembl
rs1216259641 CA340029324	1824	K>E		No	ClinGen TOPMed
rs972813693 CA21677852	1824	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
rs1408438550 CA340029456	1831	Q>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA340029473 rs1339202074	1833	G>E		No	ClinGen TOPMed
TCGA novel	1833	G>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA813560 rs755667245	1834	P>S		No	ClinGen ExAC TOPMed gnomAD
rs746411435 CA340029512	1836	T>K		No	ClinGen ExAC gnomAD
rs746411435 CA813562	1836	T>M		No	ClinGen ExAC gnomAD
CA340029507 rs1292169218	1836	T>S		No	ClinGen TOPMed
rs1212745213 CA340029699	1843	V>M		No	ClinGen gnomAD
rs1234724539 CA340029737	1845	R>C		No	ClinGen TOPMed
rs755382808 CA813585	1847	G>R		No	ClinGen ExAC TOPMed gnomAD
CA21677999 rs202216723	1848	V>A		No	ClinGen 1000Genomes TOPMed
CA340029800 rs1386581708	1848	V>L		No	ClinGen TOPMed
CA21678000 rs1010214181	1850	I>L		No	ClinGen TOPMed
CA813587 rs748431718	1850	I>T		No	ClinGen ExAC gnomAD
rs1010214181 CA340029853	1850	I>V		No	ClinGen TOPMed
rs1441420459 CA340029883	1851	T>S		No	ClinGen TOPMed gnomAD
CA340029959 rs1384223816	1854	I>T		No	ClinGen gnomAD
CA813588 rs770052959	1854	I>V		No	ClinGen ExAC gnomAD
rs150260807 CA813590	1855	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA813592 rs774364089	1858	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA340030027 rs1175556576	1858	R>H		No	ClinGen TOPMed
rs1378513685 CA340030032	1859	M>V		No	ClinGen gnomAD
CA340030049 rs1570758725	1860	R>C		No	ClinGen Ensembl
CA813593 rs373895014	1860	R>H		No	ClinGen ESP ExAC TOPMed gnomAD
rs1143702 CA21678026	1861	Y>*		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1349236746 CA340030066	1861	Y>C		No	ClinGen TOPMed gnomAD
rs771936458 CA340030061	1861	Y>D		No	ClinGen ExAC TOPMed gnomAD
rs1349236746 CA340030068	1861	Y>F		No	ClinGen TOPMed gnomAD
CA813594 rs771936458	1861	Y>H		No	ClinGen ExAC TOPMed gnomAD
CA813597 rs763894460	1864	V>M		No	ClinGen ExAC gnomAD
rs866290185 CA21678039	1866	D>G		No	ClinGen Ensembl
CA813599 rs761408146	1866	D>N		No	ClinGen ExAC TOPMed gnomAD
rs766934711 CA340030173 CA813600	1867	M>I		No	ClinGen ExAC TOPMed gnomAD
CA340030161 rs1351651395	1867	M>L		No	ClinGen TOPMed gnomAD
CA340030159 rs1351651395	1867	M>V		No	ClinGen TOPMed gnomAD
rs752128149 CA813601	1869	Q>P		No	ClinGen ExAC gnomAD
CA813603 rs781600148 COSM1263472	1871	V>M	oesophagus [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
CA340030246 rs1570759316	1873	T>P		No	ClinGen Ensembl
CA340030248 rs1570759316	1873	T>S		No	ClinGen Ensembl
rs753061964 CA813604	1874	L>R		No	ClinGen ExAC gnomAD
CA21678107 rs990623648	1874	L>V		No	ClinGen gnomAD
rs756325478 CA813605	1875	R>H		No	ClinGen ExAC gnomAD
rs368302488 CA813607	1876	T>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA340030271 rs1446869120	1877	Q>H		No	ClinGen gnomAD
rs1376848279 CA340030297	1881	M>I		No	ClinGen TOPMed
CA21678120 rs962970239	1884	T>A		No	ClinGen TOPMed gnomAD
CA340030314 rs962970239	1884	T>S		No	ClinGen TOPMed gnomAD
TCGA novel	1885	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1342550191 CA340030342	1886	D>A		No	ClinGen gnomAD
CA340030343 rs1342550191	1886	D>G		No	ClinGen gnomAD
CA813636 RCV000980615 rs200249684	1889	Q>R		No	ClinGen ClinVar 1000Genomes ExAC dbSNP gnomAD
rs986176825 CA21678719	1893	R>C		No	ClinGen TOPMed gnomAD
CA340030392 rs986176825	1893	R>G		No	ClinGen TOPMed gnomAD
RCV000908232 rs141490430 CA813639	1893	R>H		No	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs764413298 CA813640	1894	A>V		No	ClinGen ExAC TOPMed gnomAD
rs757485025 CA813642	1899	L>F		No	ClinGen ExAC gnomAD
CA813644 rs750446848	1900	G>S		No	ClinGen ExAC TOPMed gnomAD
CA340030442 rs1384098301	1901	S>I		No	ClinGen gnomAD
rs1458174624 CA340030445	1902	F>I		No	ClinGen TOPMed
CA21678776 rs145316280	1905	Y>C		No	ClinGen ESP gnomAD
TCGA novel	1905	Y>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1287556112 CA340030487	1907	T>M		No	ClinGen TOPMed gnomAD

1 associated diseases with P10586

[MIM: 616001]: Aplasia or hypoplasia of the breasts and/or nipples 2 (BNAH2)

A group of congenital deformities encompassing total absence of breasts and nipple (amastia), absence of the nipple (athelia), and absence of the mammary gland (amazia). {ECO:0000269|PubMed:24781087}. Note=The disease is caused by variants affecting the gene represented in this entry.

Without disease ID

A group of congenital deformities encompassing total absence of breasts and nipple (amastia), absence of the nipple (athelia), and absence of the mammary gland (amazia). {ECO:0000269|PubMed:24781087}. Note=The disease is caused by variants affecting the gene represented in this entry.

28 regional properties for P10586

Type	Name	Position	InterPro Accession
domain	Tyrosine-specific protein phosphatase, PTPase domain	1351 - 1609	IPR000242-1
domain	Tyrosine-specific protein phosphatase, PTPase domain	1638 - 1900	IPR000242-2
domain	Tyrosine-specific protein phosphatases domain	1527 - 1598	IPR000387-1
domain	Tyrosine-specific protein phosphatases domain	1816 - 1889	IPR000387-2
domain	Protein-tyrosine phosphatase, catalytic	1505 - 1606	IPR003595-1
domain	Protein-tyrosine phosphatase, catalytic	1794 - 1897	IPR003595-2
domain	Immunoglobulin subtype 2	45 - 114	IPR003598-1
domain	Immunoglobulin subtype 2	147 - 214	IPR003598-2
domain	Immunoglobulin subtype 2	244 - 305	IPR003598-3
domain	Immunoglobulin subtype	39 - 125	IPR003599-1
domain	Immunoglobulin subtype	141 - 226	IPR003599-2
domain	Immunoglobulin subtype	238 - 316	IPR003599-3
domain	Fibronectin type III	319 - 411	IPR003961-1
domain	Fibronectin type III	414 - 510	IPR003961-2
domain	Fibronectin type III	512 - 604	IPR003961-3
domain	Fibronectin type III	606 - 706	IPR003961-4
domain	Fibronectin type III	709 - 819	IPR003961-5
domain	Fibronectin type III	820 - 914	IPR003961-6
domain	Fibronectin type III	916 - 1010	IPR003961-7
domain	Fibronectin type III	1012 - 1088	IPR003961-8
domain	Immunoglobulin-like domain	33 - 123	IPR007110-1
domain	Immunoglobulin-like domain	135 - 224	IPR007110-2
domain	Immunoglobulin-like domain	232 - 314	IPR007110-3
domain	Immunoglobulin I-set	33 - 124	IPR013098-1
domain	Immunoglobulin I-set	135 - 216	IPR013098-2
domain	Immunoglobulin I-set	232 - 315	IPR013098-3
active_site	Protein-tyrosine phosphatase, active site	1546 - 1556	IPR016130-1
active_site	Protein-tyrosine phosphatase, active site	1837 - 1847	IPR016130-2

Functions

		Description
EC Number	3.1.3.48	Phosphoric monoester hydrolases
Subcellular Localization	Membrane; Single-pass type I membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

5 GO annotations of cellular component

Name	Definition
extracellular exosome	A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
integral component of plasma membrane	The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
neuron projection	A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
neuronal cell body	The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
plasma membrane	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

6 GO annotations of molecular function

Name	Definition
cell adhesion molecule binding	Binding to a cell adhesion molecule.
chondroitin sulfate proteoglycan binding	Binding to a chondroitin sulfate proteoglycan, any proteoglycan containing chondroitin sulfate as the glycosaminoglycan carbohydrate unit.
heparin binding	Binding to heparin, a member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
protein tyrosine phosphatase activity	Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
protein-containing complex binding	Binding to a macromolecular complex.
transmembrane receptor protein tyrosine phosphatase activity	Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

9 GO annotations of biological process

Name	Definition
cell adhesion	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
cell migration	The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
negative regulation of receptor binding	Any process that stops, prevents or reduces the frequency, rate or extent of a protein or other molecule binding to a receptor.
neuron projection regeneration	The regrowth of neuronal processes such as axons or dendrites in response to their loss or damage.
peptidyl-tyrosine dephosphorylation	The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine.
protein dephosphorylation	The process of removing one or more phosphoric residues from a protein.
regulation of axon regeneration	Any process that modulates the frequency, rate or extent of axon regeneration.
synaptic membrane adhesion	The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane.
transmembrane receptor protein tyrosine phosphatase signaling pathway	The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses protein tyrosine phosphatase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.

9 homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
P08575	PTPRC	Receptor-type tyrosine-protein phosphatase C	Homo sapiens (Human)	PR
P28827	PTPRM	Receptor-type tyrosine-protein phosphatase mu	Homo sapiens (Human)	PR
Q15262	PTPRK	Receptor-type tyrosine-protein phosphatase kappa	Homo sapiens (Human)	PR
P23468	PTPRD	Receptor-type tyrosine-protein phosphatase delta	Homo sapiens (Human)	PR
Q13332	PTPRS	Receptor-type tyrosine-protein phosphatase S	Homo sapiens (Human)	PR
P43378	PTPN9	Tyrosine-protein phosphatase non-receptor type 9	Homo sapiens (Human)	PR
P49446	Ptpre	Receptor-type tyrosine-protein phosphatase epsilon	Mus musculus (Mouse)	PR
Q64487	Ptprd	Receptor-type tyrosine-protein phosphatase delta	Mus musculus (Mouse)	PR
P35822	Ptprk	Receptor-type tyrosine-protein phosphatase kappa	Mus musculus (Mouse)	PR

10	20	30	40	50	60
MAPEPAPGRT	MVPLVPALVM	LGLVAGAHGD	SKPVFIKVPE	DQTGLSGGVA	SFVCQATGEP
70	80	90	100	110	120
KPRITWMKKG	KKVSSQRFEV	IEFDDGAGSV	LRIQPLRVQR	DEAIYECTAT	NSLGEINTSA
130	140	150	160	170	180
KLSVLEEEQL	PPGFPSIDMG	PQLKVVEKAR	TATMLCAAGG	NPDPEISWFK	DFLPVDPATS
190	200	210	220	230	240
NGRIKQLRSG	ALQIESSEES	DQGKYECVAT	NSAGTRYSAP	ANLYVRVRRV	APRFSIPPSS
250	260	270	280	290	300
QEVMPGGSVN	LTCVAVGAPM	PYVKWMMGAE	ELTKEDEMPV	GRNVLELSNV	VRSANYTCVA
310	320	330	340	350	360
ISSLGMIEAT	AQVTVKALPK	PPIDLVVTET	TATSVTLTWD	SGNSEPVTYY	GIQYRAAGTE
370	380	390	400	410	420
GPFQEVDGVA	TTRYSIGGLS	PFSEYAFRVL	AVNSIGRGPP	SEAVRARTGE	QAPSSPPRRV
430	440	450	460	470	480
QARMLSASTM	LVQWEPPEEP	NGLVRGYRVY	YTPDSRRPPN	AWHKHNTDAG	LLTTVGSLLP
490	500	510	520	530	540
GITYSLRVLA	FTAVGDGPPS	PTIQVKTQQG	VPAQPADFQA	EVESDTRIQL	SWLLPPQERI
550	560	570	580	590	600
IMYELVYWAA	EDEDQQHKVT	FDPTSSYTLE	DLKPDTLYRF	QLAARSDMGV	GVFTPTIEAR
610	620	630	640	650	660
TAQSTPSAPP	QKVMCVSMGS	TTVRVSWVPP	PADSRNGVIT	QYSVAYEAVD	GEDRGRHVVD
670	680	690	700	710	720
GISREHSSWD	LVGLEKWTEY	RVWVRAHTDV	GPGPESSPVL	VRTDEDVPSG	PPRKVEVEPL
730	740	750	760	770	780
NSTAVHVYWK	LPVPSKQHGQ	IRGYQVTYVR	LENGEPRGLP	IIQDVMLAEA	QWRPEESEDY
790	800	810	820	830	840
ETTISGLTPE	TTYSVTVAAY	TTKGDGARSK	PKIVTTTGAV	PGRPTMMIST	TAMNTALLQW
850	860	870	880	890	900
HPPKELPGEL	LGYRLQYCRA	DEARPNTIDF	GKDDQHFTVT	GLHKGTTYIF	RLAAKNRAGL
910	920	930	940	950	960
GEEFEKEIRT	PEDLPSGFPQ	NLHVTGLTTS	TTELAWDPPV	LAERNGRIIS	YTVVFRDINS
970	980	990	1000	1010	1020
QQELQNITTD	TRFTLTGLKP	DTTYDIKVRA	WTSKGSGPLS	PSIQSRTMPV	EQVFAKNFRV
1030	1040	1050	1060	1070	1080
AAAMKTSVLL	SWEVPDSYKS	AVPFKILYNG	QSVEVDGHSM	RKLIADLQPN	TEYSFVLMNR
1090	1100	1110	1120	1130	1140
GSSAGGLQHL	VSIRTAPDLL	PHKPLPASAY	IEDGRFDLSM	PHVQDPSLVR	WFYIVVVPID
1150	1160	1170	1180	1190	1200
RVGGSMLTPR	WSTPEELELD	ELLEAIEQGG	EEQRRRRRQA	ERLKPYVAAQ	LDVLPETFTL
1210	1220	1230	1240	1250	1260
GDKKNYRGFY	NRPLSPDLSY	QCFVLASLKE	PMDQKRYASS	PYSDEIVVQV	TPAQQQEEPE
1270	1280	1290	1300	1310	1320
MLWVTGPVLA	VILIILIVIA	ILLFKRKRTH	SPSSKDEQSI	GLKDSLLAHS	SDPVEMRRLN
1330	1340	1350	1360	1370	1380
YQTPGMRDHP	PIPITDLADN	IERLKANDGL	KFSQEYESID	PGQQFTWENS	NLEVNKPKNR
1390	1400	1410	1420	1430	1440
YANVIAYDHS	RVILTSIDGV	PGSDYINANY	IDGYRKQNAY	IATQGPLPET	MGDFWRMVWE
1450	1460	1470	1480	1490	1500
QRTATVVMMT	RLEEKSRVKC	DQYWPARGTE	TCGLIQVTLL	DTVELATYTV	RTFALHKSGS
1510	1520	1530	1540	1550	1560
SEKRELRQFQ	FMAWPDHGVP	EYPTPILAFL	RRVKACNPLD	AGPMVVHCSA	GVGRTGCFIV
1570	1580	1590	1600	1610	1620
IDAMLERMKH	EKTVDIYGHV	TCMRSQRNYM	VQTEDQYVFI	HEALLEAATC	GHTEVPARNL
1630	1640	1650	1660	1670	1680
YAHIQKLGQV	PPGESVTAME	LEFKLLASSK	AHTSRFISAN	LPCNKFKNRL	VNIMPYELTR
1690	1700	1710	1720	1730	1740
VCLQPIRGVE	GSDYINASFL	DGYRQQKAYI	ATQGPLAEST	EDFWRMLWEH	NSTIIVMLTK
1750	1760	1770	1780	1790	1800
LREMGREKCH	QYWPAERSAR	YQYFVVDPMA	EYNMPQYILR	EFKVTDARDG	QSRTIRQFQF
1810	1820	1830	1840	1850	1860
TDWPEQGVPK	TGEGFIDFIG	QVHKTKEQFG	QDGPITVHCS	AGVGRTGVFI	TLSIVLERMR
1870	1880	1890	1900
YEGVVDMFQT	VKTLRTQRPA	MVQTEDQYQL	CYRAALEYLG	SFDHYAT