F4JJJ3
PR
Gene name |
NDB3 (At4g21490, F18E5.110) |
Protein name |
External alternative NAD(P)H-ubiquinone oxidoreductase B3, mitochondrial |
Names |
External alternative NADH dehydrogenase NDB3, NADH:ubiquinone reductase (non-electrogenic) NDB3 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT4G21490 |
EC number |
1.6.5.9: With a quinone or similar compound as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for F4JJJ3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-F4JJJ3-F1 | Predicted | AlphaFoldDB |
72 variants for F4JJJ3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH02901342 | 5 | A>T | No | 1000Genomes | |
| ENSVATH00528732 | 6 | Y>F | No | 1000Genomes | |
| ENSVATH12115038 | 8 | E>K | No | 1000Genomes | |
| ENSVATH02901339 | 12 | Q>K | No | 1000Genomes | |
| ENSVATH06744373 | 28 | T>P | No | 1000Genomes | |
| ENSVATH12114962 | 40 | A>T | No | 1000Genomes | |
| tmp_4_11438864_A_G | 44 | Y>H | No | 1000Genomes | |
| ENSVATH00528727 | 56 | R>K | No | 1000Genomes | |
| tmp_4_11438816_G_C | 60 | L>V | No | 1000Genomes | |
| tmp_4_11438810_C_T | 62 | G>R | No | 1000Genomes | |
| ENSVATH06744365 | 102 | G>R | No | 1000Genomes | |
| tmp_4_11438661_T_G | 111 | E>D | No | 1000Genomes | |
| tmp_4_11438663_C_T | 111 | E>K | No | 1000Genomes | |
| ENSVATH12114959 | 124 | M>I | No | 1000Genomes | |
| ENSVATH02901312 | 137 | G>R | No | 1000Genomes | |
| tmp_4_11438467_A_T | 149 | V>E | No | 1000Genomes | |
| ENSVATH06744361 | 152 | K>N | No | 1000Genomes | |
| ENSVATH06744360 | 153 | G>R | No | 1000Genomes | |
| ENSVATH06744359 | 165 | V>I | No | 1000Genomes | |
| ENSVATH06744356 | 177 | I>V | No | 1000Genomes | |
| tmp_4_11438363_A_C | 184 | C>G | No | 1000Genomes | |
| ENSVATH06744354 | 185 | H>N | No | 1000Genomes | |
| ENSVATH14272776 | 207 | A>T | No | 1000Genomes | |
| tmp_4_11438214_T_C | 208 | S>G | No | 1000Genomes | |
| ENSVATH00528722 | 211 | G>R | No | 1000Genomes | |
| tmp_4_11438190_C_T | 216 | E>K | No | 1000Genomes | |
| tmp_4_11438186_C_A | 217 | R>I | No | 1000Genomes | |
| ENSVATH14272775 | 256 | N>I | No | 1000Genomes | |
| tmp_4_11437842_T_A | 309 | K>I | No | 1000Genomes | |
| ENSVATH02901304 | 311 | K>R | No | 1000Genomes | |
| ENSVATH02901303 | 312 | A>G | No | 1000Genomes | |
| tmp_4_11437831_C_A | 313 | G>* | No | 1000Genomes | |
| ENSVATH06744347 | 317 | T>I | No | 1000Genomes | |
| ENSVATH06744346 | 319 | P>T | No | 1000Genomes | |
| tmp_4_11437802_C_G | 322 | M>I | No | 1000Genomes | |
| ENSVATH00528718 | 335 | I>V | No | 1000Genomes | |
| tmp_4_11437582_T_G | 364 | I>L | No | 1000Genomes | |
| tmp_4_11437578_T_G | 365 | Y>S | No | 1000Genomes | |
| ENSVATH12114932 | 366 | A>T | No | 1000Genomes | |
| ENSVATH12114926 | 383 | A>G | No | 1000Genomes | |
| ENSVATH12114925 | 385 | I>T | No | 1000Genomes | |
| ENSVATH06744344 | 385 | I>V | No | 1000Genomes | |
| ENSVATH06744343 | 386 | F>Y | No | 1000Genomes | |
| ENSVATH12114884 | 389 | A>V | No | 1000Genomes | |
| ENSVATH02901294 | 392 | E>K | No | 1000Genomes | |
| ENSVATH06744342 | 395 | G>R | No | 1000Genomes | |
| tmp_4_11437382_A_T | 399 | M>K | No | 1000Genomes | |
| ENSVATH12114883 | 404 | E>D | No | 1000Genomes | |
| tmp_4_11437355_T_A | 408 | D>V | No | 1000Genomes | |
| ENSVATH02901293 | 416 | V>M | No | 1000Genomes | |
| tmp_4_11437299_C_A | 427 | G>C | No | 1000Genomes | |
| tmp_4_11437280_T_G | 433 | K>T | No | 1000Genomes | |
| tmp_4_11437274_G_A | 435 | A>V | No | 1000Genomes | |
| tmp_4_11437266_C_T | 438 | E>K | No | 1000Genomes | |
| tmp_4_11437253_T_A | 442 | N>I | No | 1000Genomes | |
| tmp_4_11437225_T_G | 451 | E>D | No | 1000Genomes | |
| ENSVATH12114882 | 452 | L>V | No | 1000Genomes | |
| tmp_4_11437208_C_G | 457 | C>S | No | 1000Genomes | |
| ENSVATH00528714 | 466 | L>R | No | 1000Genomes | |
| tmp_4_11437041_G_A | 476 | Q>* | No | 1000Genomes | |
| ENSVATH00528711 | 477 | G>E | No | 1000Genomes | |
| ENSVATH00528709 | 488 | E>* | No | 1000Genomes | |
| tmp_4_11436964_T_A | 501 | R>S | No | 1000Genomes | |
| ENSVATH06744338 | 502 | G>R | No | 1000Genomes | |
| ENSVATH12114878 | 510 | P>L | No | 1000Genomes | |
| ENSVATH06744337 | 512 | R>S | No | 1000Genomes | |
| tmp_4_11436778_C_G | 520 | A>P | No | 1000Genomes | |
| tmp_4_11436742_G_A | 532 | P>S | No | 1000Genomes | |
| tmp_4_11436738_C_T | 533 | G>E | No | 1000Genomes | |
| tmp_4_11436685_C_G | 551 | A>P | No | 1000Genomes | |
| tmp_4_11436579_C_G | 553 | K>N | No | 1000Genomes | |
| ENSVATH12114836 | 581 | I>R | No | 1000Genomes |
No associated diseases with F4JJJ3
Functions
| Description | ||
|---|---|---|
| EC Number | 1.6.5.9 | With a quinone or similar compound as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrial inner membrane | The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. |
| mitochondrial intermembrane space | The region between the inner and outer lipid bilayers of the mitochondrial envelope. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
| peroxisome | A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| calcium ion binding | Binding to a calcium ion (Ca2+). |
| NADH dehydrogenase (quinone) activity | Catalysis of the reaction: NADH + H+ + a quinone = NAD+ + a quinol. |
| oxidoreductase activity | Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| NADH oxidation | A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADH, to the oxidized form, NAD. |
7 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P32340 | NDI1 | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q07500 | NDE2 | External NADH-ubiquinone oxidoreductase 2, mitochondrial | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| P40215 | NDE1 | External NADH-ubiquinone oxidoreductase 1, mitochondrial | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| M1BYJ7 | NDB1 | External alternative NAD(P)H-ubiquinone oxidoreductase B1, mitochondrial | Solanum tuberosum (Potato) | PR |
| Q1JPL4 | NDB1 | External alternative NAD(P)H-ubiquinone oxidoreductase B1, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GWA1 | NDA1 | Internal alternative NAD(P)H-ubiquinone oxidoreductase A1, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94BV7 | NDB2 | External alternative NAD(P)H-ubiquinone oxidoreductase B2, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRPFAYFERL | SQAFHDYPSL | SKILVVSTIS | GGGLIVYSEA | NPSYSNNGVE | TKTRKRKVVL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LGTGWAGASF | LKTLNNSSYE | VQVISPRNYF | AFTPLLPSVT | CGTVEARSVV | EPIRNIARKQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NVEMSFLEAE | CFKIDPGSKK | VYCRSKQGVN | SKGKKEFDVD | YDYLVIATGA | QSNTFNIPGV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EENCHFLKEV | EDAQRIRSTV | IDSFEKASLP | GLNEQERKRM | LHFVVVGGGP | TGVEFASELH |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DFVNEDLVKL | YPKAKNLVQI | TLLEAADHIL | TMFDKRITEF | AEEKFTRDGI | DVKLGSMVVK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VNDKEISAKT | KAGEVSTIPY | GMIVWSTGIG | TRPVIKDFMK | QIGQGNRRAL | ATDEWLRVEG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| CDNIYALGDC | ATINQRKVME | DIAAIFKKAD | KENSGTLTMK | EFHEVMSDIC | DRYPQVELYL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KSKGMHGITD | LLKQAQAENG | SNKSVELDIE | ELKSALCQVD | SQVKLLPATG | QVAAQQGTYL |
| 490 | 500 | 510 | 520 | 530 | 540 |
| AKCFDRMEVC | EKNPEGPIRI | RGEGRHRFRP | FRYRHLGQFA | PLGGEQTAAQ | LPGDWVSIGH |
| 550 | 560 | 570 | |||
| SSQWLWYSVY | ASKQVSWRTR | VLVVSDWMRR | FIFGRDSSRI |