F4HXY7
Gene name |
PSS1 (At1g15110, F9L1.4) |
Protein name |
CDP-diacylglycerol--serine O-phosphatidyltransferase 1 |
Names |
Phosphatidylserine synthase 1 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G15110 |
EC number |
2.7.8.8: Transferases for other substituted phosphate groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for F4HXY7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-F4HXY7-F1 | Predicted | AlphaFoldDB |
11 variants for F4HXY7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_1_5199597_G_A | 2 | E>K | No | 1000Genomes | |
| ENSVATH00024343 | 63 | D>E | No | 1000Genomes | |
| ENSVATH11252355 | 68 | D>N | No | 1000Genomes | |
| ENSVATH04579856 | 164 | T>A | No | 1000Genomes | |
| ENSVATH00024350 | 211 | V>L | No | 1000Genomes | |
| tmp_1_5201171_A_G | 269 | K>R | No | 1000Genomes | |
| ENSVATH13900219 | 288 | H>Y | No | 1000Genomes | |
| ENSVATH04579864 | 305 | I>T | No | 1000Genomes | |
| tmp_1_5201825_G_A | 399 | G>R | No | 1000Genomes | |
| ENSVATH00024353 | 422 | Q>H | No | 1000Genomes | |
| ENSVATH01053996 | 425 | R>C | No | 1000Genomes |
No associated diseases with F4HXY7
No regional properties for F4HXY7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for F4HXY7 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.8.8 | Transferases for other substituted phosphate groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| nuclear membrane | Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| CDP-diacylglycerol-serine O-phosphatidyltransferase activity | Catalysis of the reaction: CDP-diacylglycerol + L-serine = CMP + O-sn-phosphatidyl-L-serine. |
| L-serine-phosphatidylethanolamine phosphatidyltransferase activity | Catalysis of the reaction: L-1-phosphatidylethanolamine + L-serine <=> L-1-phosphatidylserine + ethanolamine. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| microsporogenesis | The process in which the microsporocyte undergoes meiosis, giving rise to four haploid microspores. |
| phosphatidylethanolamine biosynthetic process | The chemical reactions and pathways resulting in the formation of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine. |
| phosphatidylserine biosynthetic process | The chemical reactions and pathways resulting in the formation of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine. |
11 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q2KHY9 | PTDSS1 | Phosphatidylserine synthase 1 | Bos taurus (Bovine) | PR |
| E1BYA3 | PTDSS1 | Phosphatidylserine synthase 2 | Gallus gallus (Chicken) | PR |
| Q5ZM65 | PTDSS1 | Phosphatidylserine synthase 1 | Gallus gallus (Chicken) | PR |
| P48651 | PTDSS1 | Phosphatidylserine synthase 1 | Homo sapiens (Human) | PR |
| Q99LH2 | Ptdss1 | Phosphatidylserine synthase 1 | Mus musculus (Mouse) | PR |
| Q9Z1X2 | Ptdss2 | Phosphatidylserine synthase 2 | Mus musculus (Mouse) | PR |
| Q5PQL5 | Ptdss1 | Phosphatidylserine synthase 1 | Rattus norvegicus (Rat) | PR |
| Q6I628 | PSS2 | CDP-diacylglycerol--serine O-phosphatidyltransferase 2 | Oryza sativa subsp japonica (Rice) | PR |
| Q5N8Q3 | PSS3 | CDP-diacylglycerol--serine O-phosphatidyltransferase 3 | Oryza sativa subsp japonica (Rice) | PR |
| Q08D11 | ptdss2 | Phosphatidylserine synthase 2 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| E7EY42 | ptdss2 | Phosphatidylserine synthase 2 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEPNGYRKER | RKEQHLGRMN | GGGGDVETDL | DPWTAWAYKP | RTISLLLIGA | CFLIWASGAL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DPDSTTSDDL | VTSVKRGVWA | MIAVFLAYSL | LQAPSTVLIR | PHPAIWRLVH | GMAVIYLVAL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TFLLFQRRDD | ARQFMKFLHP | DLGIELPEKS | YGADCRIYVP | DHPTNRFKNL | YDTVFDEFFL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AHIFGWWGKA | ILIRNQPLLW | VLSIGFELLE | VTFRHMLPNF | NECWWDSIVL | DILICNWFGI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| WAGMYTVRYF | DGKTYEWVGI | SRQPNIIGKV | KRTLGQFTPA | HWDKDEWHPL | QGPWRFIQVL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| TLCIIFLTVE | LNTFFLKFSL | WIPPRNPVIL | YRLILWWLIA | IPTTREYNSY | LQDRKPVKKV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GAFCWLSLGI | CIVELLICIK | FGSGLYPTEM | PLWVVTLWGS | VGLGLVAFLL | SWTWKIQKIL |
| AQKRR |