Q9U2A9
Gene name |
Y48B6A.1 |
Protein name |
Ribosome biogenesis protein BOP1 homolog |
Names |
|
Species |
Caenorhabditis elegans |
KEGG Pathway |
cel:CELE_Y48B6A.1 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9U2A9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9U2A9-F1 | Predicted | AlphaFoldDB |
No variants for Q9U2A9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9U2A9 | |||||
No associated diseases with Q9U2A9
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
| PeBoW complex | A protein complex that is involved in coordinating ribosome biogenesis with cell cycle progression. In human, it is composed of Pes1, Bop1, and WDR12; in Saccharomyces the proteins are known as Nop7p, Erb1 and Ytm1 respectively. |
| preribosome, large subunit precursor | A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| ribonucleoprotein complex binding | Binding to a complex of RNA and protein. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | Any process involved in the maturation of an rRNA molecule originally produced as part of a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. |
| maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript. |
6 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q04660 | ERB1 | Ribosome biogenesis protein ERB1 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q7K0Y1 | CG5033 | Ribosome biogenesis protein BOP1 homolog | Drosophila melanogaster (Fruit fly) | PR |
| Q14137 | BOP1 | Ribosome biogenesis protein BOP1 | Homo sapiens (Human) | PR |
| P97452 | Bop1 | Ribosome biogenesis protein BOP1 | Mus musculus (Mouse) | PR |
| Q562C2 | Bop1 | Ribosome biogenesis protein BOP1 | Rattus norvegicus (Rat) | PR |
| A0JMQ0 | bop1 | Ribosome biogenesis protein bop1 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MASTSAATPL | KNKRKFENGK | KKPKTLKDEF | GEKLDIKPVI | VPPKPADEYD | YDSSDEEDLR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NTIGNIPIKW | YDDEDHIGYD | KFGEKIAKPA | KKGEIETFLE | KMEDPDYWRK | VFDKQTGTDV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KLTDEQIEKI | HNIATGKYPT | IGYNPYEPFL | DIFSSQKEIH | PIDNRPEPKS | RFIPSKDEMR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| MVSRMVHAIK | MGWAKGPRAK | KEEHKSYDLW | ASEDALDNVT | KSQLSRMRVH | MPAPKVALPT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| HAESYNPPEE | YIFDDEERKK | WEEAEKEDRV | LNFMPSKYDA | LRKVPQYDKF | ITERFERCLD |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LYLAPRQRKM | RIHADPTDLL | PDLPNPNDLR | PFPTTLAFYM | RGHTGQVRAI | TVEPERGELL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ASGGEDGTVR | IWMIATGRCI | KTFQMDGEVT | SVSFSPVADR | TLLAVAYEGK | YVAILNTGCG |
| 430 | 440 | 450 | 460 | 470 | 480 |
| DRLHVQQTEA | LLAETPTDAQ | EDGAVVTWRK | SKEKLMLKMP | NEVRQVTWHS | KGDYFASVAI |
| 490 | 500 | 510 | 520 | 530 | 540 |
| DDIAKSVYVH | QLSKAKSQCP | FQKRKGHVQA | VTFHPTQARL | FVATKIHVRE | YDLARCVLVK |
| 550 | 560 | 570 | 580 | 590 | 600 |
| KLITGCKHIS | TMATDANGEN | LFLGGLDRRF | CWMDLQMGNK | PWKKLKHHTA | AVRSVAYHKK |
| 610 | 620 | 630 | 640 | 650 | 660 |
| YPLLATVSDD | GTAMVYYARI | YTDFVKDNEL | YPVKRLRAHE | KTPNDLCMLH | TTWHPTQPWL |
| 670 | |||||
| ITAGADGTIA | LFTY |