Q7K0Y1
Gene name |
CG5033 |
Protein name |
Ribosome biogenesis protein BOP1 homolog |
Names |
|
Species |
Drosophila melanogaster (Fruit fly) |
KEGG Pathway |
dme:Dmel_CG5033 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q7K0Y1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q7K0Y1-F1 | Predicted | AlphaFoldDB |
No variants for Q7K0Y1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q7K0Y1 | |||||
No associated diseases with Q7K0Y1
No regional properties for Q7K0Y1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q7K0Y1 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
| PeBoW complex | A protein complex that is involved in coordinating ribosome biogenesis with cell cycle progression. In human, it is composed of Pes1, Bop1, and WDR12; in Saccharomyces the proteins are known as Nop7p, Erb1 and Ytm1 respectively. |
| preribosome, large subunit precursor | A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| ribonucleoprotein complex binding | Binding to a complex of RNA and protein. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | Any process involved in the maturation of an rRNA molecule originally produced as part of a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. |
| maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript. |
| regulation of hemocyte proliferation | Any process that modulates the frequency, rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster. |
6 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q04660 | ERB1 | Ribosome biogenesis protein ERB1 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q14137 | BOP1 | Ribosome biogenesis protein BOP1 | Homo sapiens (Human) | PR |
| P97452 | Bop1 | Ribosome biogenesis protein BOP1 | Mus musculus (Mouse) | PR |
| Q562C2 | Bop1 | Ribosome biogenesis protein BOP1 | Rattus norvegicus (Rat) | PR |
| Q9U2A9 | Y48B6A.1 | Ribosome biogenesis protein BOP1 homolog | Caenorhabditis elegans | PR |
| A0JMQ0 | bop1 | Ribosome biogenesis protein bop1 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTKKLALKRR | GKDSEPTNEV | VASSEASENE | EEEEDLLQAV | KDPGEDSTDD | EGIDQEYHSD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SSEELQFESD | EEGNYLGRKQ | SSSAEEDEES | SDEEDNEEEE | STDGEEVEDE | EKDSKSKQTD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DKPSGSGAAS | KKALTAELPK | RDSSKPEYQD | SDTSDEEDIR | NTVGNIPMHW | YDEYKHIGYD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| WDAKKIIKPP | QGDQIDEFLR | KIEDPDFWRT | VKDPLTGQDV | RLTDEDIALI | KRIVSGRIPN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KDHEEYEPWI | EWFTSEVEKM | PIKNVPDHKR | SFLPSVSEKK | RVSRMVHALK | MGWMKTTEEV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EREKQAKRGP | KFYMLWETDT | SREHMRRIHD | PVSAPKRDLP | GHAESYNPPP | EYLFDAKETK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| EWLKLKDEPH | KRKLHFMPQK | FKSLREVPAY | SRYLRERFLR | CLDLYLCPRA | KRVKLNIDAE |
| 430 | 440 | 450 | 460 | 470 | 480 |
| YLIPKLPSPR | DLQPFPTVES | MVYRGHTDLV | RSVSVEPKGE | YLVSGSDDKT | VKIWEIATGR |
| 490 | 500 | 510 | 520 | 530 | 540 |
| CIRTIETDEV | VRCVAWCPNP | KLSIIAVATG | NRLLLVNPKV | GDKVLVKKTD | DLLAEAPSQD |
| 550 | 560 | 570 | 580 | 590 | 600 |
| VIESERIKTA | VQWSNAEADE | QEKGVRVVIT | HFKPIRQVTW | HGRGDYLATV | MPEGANRSAL |
| 610 | 620 | 630 | 640 | 650 | 660 |
| IHQLSKRRSQ | IPFSKSKGLI | QFVLFHPVKP | CFFVATQHNI | RIYDLVKQEL | VKKLLTNSKW |
| 670 | 680 | 690 | 700 | 710 | 720 |
| ISGMSIHPKG | DNLLVSTYDK | KMLWFDLDLS | TKPYQTMRLH | RNAVRSVAFH | LRYPLFASGS |
| 730 | 740 | 750 | 760 | 770 | 780 |
| DDQAVIVSHG | MVYNDLLQNP | LIVPLKKLQT | HEKRDEFGVL | DVNWHPVQPW | VFSTGADSTI |
| RLYT |