Q9SR25

PR
Gene name
AEL2
Protein name
Protein AE7-like 2
Names
MIP18 family protein At3g09380
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT3G09380
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-149 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9SR25

Entry ID Method Resolution Chain Position Source
AF-Q9SR25-F1 Predicted AlphaFoldDB

19 variants for Q9SR25

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_3_2886085_A_T 4 V>E No 1000Genomes
ENSVATH05797670 14 P>L No 1000Genomes
ENSVATH00313385 20 Y>S No 1000Genomes
ENSVATH10565296 26 S>N No 1000Genomes
tmp_3_2885869_G_A 32 S>F No 1000Genomes
tmp_3_2885840_G_A 42 P>S No 1000Genomes
tmp_3_2885837_C_A 43 E>* No 1000Genomes
ENSVATH05797663 46 E>K No 1000Genomes
ENSVATH02125397 50 E>K No 1000Genomes
tmp_3_2885774_C_A 64 D>Y No 1000Genomes
ENSVATH00313383 70 R>I No 1000Genomes
ENSVATH13888347 78 P>L No 1000Genomes
ENSVATH13888347 78 P>R No 1000Genomes
tmp_3_2885617_G_T 89 C>* No 1000Genomes
ENSVATH10565270 101 R>* No 1000Genomes
tmp_3_2885476_T_A 107 R>S No 1000Genomes
ENSVATH02125390 112 S>T No 1000Genomes
ENSVATH02125389 115 K>N No 1000Genomes
ENSVATH10565228 143 N>S No 1000Genomes

No associated diseases with Q9SR25

2 regional properties for Q9SR25

Type Name Position InterPro Accession
conserved_site Aminoacyl-tRNA synthetase, class I, conserved site 42 - 52 IPR001412
domain RNA-binding S4 domain 336 - 374 IPR002942

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
chromosome segregation The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
iron-sulfur cluster assembly The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
protein maturation by [4Fe-4S] cluster transfer The transfer of an assembled 4Fe-4S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q3T0U7 CIAO2A Cytosolic iron-sulfur assembly component 2A Bos taurus (Bovine) PR
Q9H5X1 CIAO2A Cytosolic iron-sulfur assembly component 2A Homo sapiens (Human) PR
Q9DCL2 Ciao2a Cytosolic iron-sulfur assembly component 2A Mus musculus (Mouse) PR
Q9D187 Ciao2b Cytosolic iron-sulfur assembly component 2B Mus musculus (Mouse) PR
10 20 30 40 50 60
MDSVLTNKNP IIYPKRTRRY RTDQSSTDEF SSTNRIRDIK DPEHPELSLE DLNVLTEESV
70 80 90 100 110 120
EVDDHKSYVR ITFTPTLPHC HLPTHIGLCI LVKLVQSLPA RFKVDVRVAP GSHDKETTVN
130 140
KQLGDKERVT AALENPELVA LLNKMMQVC