Q9JMD3
Gene name |
Stard10 (Pctpl, Sdccag28, Sdccagg28) |
Protein name |
START domain-containing protein 10 |
Names |
StARD10, PCTP-like protein, PCTP-L, Serologically defined colon cancer antigen 28 homolog, StAR-related lipid transfer protein 10 |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:56018 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9JMD3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9JMD3-F1 | Predicted | AlphaFoldDB |
5 variants for Q9JMD3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3388929264 | 120 | R>K | No | EVA | |
| rs3388928860 | 136 | W>* | No | EVA | |
| rs3388935125 | 147 | N>Y | No | EVA | |
| rs3388917187 | 166 | S>C | No | EVA | |
| rs3388912045 | 246 | S>I | No | EVA |
No associated diseases with Q9JMD3
Functions
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| intercellular canaliculus | An extremely narrow tubular channel located between adjacent cells. An instance of this is the secretory canaliculi occurring between adjacent parietal cells in the gastric mucosa of vertebrates. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
| microvillus | Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells. |
| motile cilium | A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| lipid binding | Binding to a lipid. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| bile acid secretion | The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue. |
| lipid transport | The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. |
| positive regulation of peroxisome proliferator activated receptor signaling pathway | Any process that activates or increases the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway. |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9NQZ5 | STARD7 | StAR-related lipid transfer protein 7, mitochondrial | Homo sapiens (Human) | PR |
| Q9Y365 | STARD10 | START domain-containing protein 10 | Homo sapiens (Human) | PR |
| Q8R1R3 | Stard7 | StAR-related lipid transfer protein 7, mitochondrial | Mus musculus (Mouse) | PR |
| Q9EQG9 | Cert1 | Ceramide transfer protein | Mus musculus (Mouse) | PR |
| O17883 | strl-1 | Steroidogenic acute regulatory-like protein 1 | Caenorhabditis elegans | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEKPAASTEP | QGSRPALGRE | SVQVPDDQDF | RSFRSECEAE | VGWNLTYSKA | GVSVWVQAVE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| MDRTLHKIKC | RMECCDVPAE | TLYDVLHDIE | YRKKWDSNVI | ETFDIARLTV | NADVGYYSWR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| CPKPLKNRDV | ITLRSWLPMG | ADYIIMNYSV | KHPKYPPRKD | LVRAVSIQTG | YLIQSTGPKS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| CVITYLAQVD | PKGSLPKWVV | NKSSQFLAPK | AMKKMYKACI | KYPEWKQKHQ | PHFKPWLHPE |
| 250 | 260 | 270 | 280 | 290 | |
| QSPLPSLALS | ELSVQHADSL | ENIDESAVTE | SREERAGGAG | GEGSDDDTSL | T |