O17883

PR
Gene name
strl-1 (F52F12.7)
Protein name
Steroidogenic acute regulatory-like protein 1
Names
Species
Caenorhabditis elegans
KEGG Pathway
cel:CELE_F52F12.7
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-64 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O17883

Entry ID Method Resolution Chain Position Source
AF-O17883-F1 Predicted AlphaFoldDB

No variants for O17883

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O17883

No associated diseases with O17883

1 regional properties for O17883

Type Name Position InterPro Accession
domain START domain 52 - 255 IPR002913

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
endoplasmic reticulum-endosome membrane contact site A contact site between the endoplasmic reticulum membrane and the endosome membrane.
late endosome membrane The lipid bilayer surrounding a late endosome.

1 GO annotations of molecular function

Name Definition
lipid binding Binding to a lipid.

1 GO annotations of biological process

Name Definition
vesicle tethering to endoplasmic reticulum The initial, indirect interaction between a transport vesicle membrane and the membrane of the endoplasmic reticulum. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior fusion.

6 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q14849 STARD3 StAR-related lipid transfer protein 3 Homo sapiens (Human) PR
O95772 STARD3NL STARD3 N-terminal-like protein Homo sapiens (Human) PR
Q9Y365 STARD10 START domain-containing protein 10 Homo sapiens (Human) PR
Q61542 Stard3 StAR-related lipid transfer protein 3 Mus musculus (Mouse) PR
Q9DCI3 Stard3nl STARD3 N-terminal-like protein Mus musculus (Mouse) PR
Q9JMD3 Stard10 START domain-containing protein 10 Mus musculus (Mouse) PR
10 20 30 40 50 60
MTLLPFTCLI LLYSLGSVMS EKTNPNLTLH DVTDKLEGDD EKYATALKTC GEVFAEVEAI
70 80 90 100 110 120
FNDENYLSHA GWFKDESNNE GDVVYAKDTP HGRMVTISTE LPMPVEDVMK ETWNGMEALP
130 140 150 160 170 180
EWNQNINFAA RIAAPTSNFD IVTYGNNDVL VVSGREFVSA RIWRKVGDGF ILASRSVTVP
190 200 210 220 230 240
SFKSKHKGKV RAHLHLAGAR FRPNPENPET TLTDVVMLAD LKGYLPKMIV NQVIGRIMIM
250
DTVTNRRHFQ NLKAKRTNN