Q9CQ21

PR
Gene name
Mcts2
Protein name
Malignant T-cell-amplified sequence 2
Names
MCT-2, Multiple copies T-cell malignancies 2
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:66405
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-55 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9CQ21

Entry ID Method Resolution Chain Position Source
AF-Q9CQ21-F1 Predicted AlphaFoldDB

12 variants for Q9CQ21

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3388598730 21 V>F No EVA
rs3388592036 22 I>V No EVA
rs3388586528 42 Q>R No EVA
rs3388597742 50 V>I No EVA
rs1134465947 52 I>T No EVA
rs3388600353 53 V>M No EVA
rs587172316 119 P>L No EVA
rs3392392696 120 G>R No EVA
rs3388600338 125 T>N No EVA
rs3388602697 140 E>* No EVA
rs1133967394 173 G>E No EVA
rs1133379360 173 G>R No EVA

No associated diseases with Q9CQ21

3 regional properties for Q9CQ21

Type Name Position InterPro Accession
domain PUA domain 93 - 171 IPR002478
domain Uncharacterised domain CHP00451 63 - 172 IPR004521
domain Pre-PUA domain 5 - 89 IPR041366

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.

1 GO annotations of biological process

Name Definition
formation of translation preinitiation complex The joining of the small ribosomal subunit, ternary complex, and mRNA.

9 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P89886 ORF3 Translation machinery-associated protein 20 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
Q2KIE4 MCTS1 Malignant T-cell-amplified sequence 1 Bos taurus (Bovine) PR
Q5ZI42 MCTS1 Malignant T-cell-amplified sequence 1 Gallus gallus (Chicken) PR
Q9W445 MCTS1 Malignant T-cell-amplified sequence 1 homolog Drosophila melanogaster (Fruit fly) PR
Q9ULC4 MCTS1 Malignant T-cell-amplified sequence 1 Homo sapiens (Human) PR
Q9DB27 Mcts1 Malignant T-cell-amplified sequence 1 Mus musculus (Mouse) PR
Q4G009 Mcts1 Malignant T-cell-amplified sequence 1 Rattus norvegicus (Rat) PR
Q6DER1 mcts1 Malignant T-cell-amplified sequence 1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
Q7ZV34 mcts1 Malignant T-cell-amplified sequence 1 Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MFKKFDEKES VSNCIQLKTS VIKGIKSQLT EQFPGIEPWL NQIMPKKDPV KIVRCHEHME
70 80 90 100 110 120
ILTVNGELLF FRQRKGPFYP TLRLLHKYPF ILPHQQVDKG AIKFVLSGAN IMCPGLTSPG
130 140 150 160 170 180
AKLYTAAVDT IVAVMAEGKE HALCVGVMKM AAADIEKINK GIGIENIHYL NDGLWHMKTY
K