Q8S3C9
PR
Gene name |
DRP1D |
Protein name |
Phragmoplastin DRP1D |
Names |
Dynamin-like protein 1D, Dynamin-like protein DLP3, Dynamin-related protein 1D, AtDRP1D |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G44590 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8S3C9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8S3C9-F1 | Predicted | AlphaFoldDB |
85 variants for Q8S3C9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH01988247 | 24 | D>H | No | 1000Genomes | |
| ENSVATH00274931 | 25 | S>N | No | 1000Genomes | |
| tmp_2_18406850_C_A | 38 | V>F | No | 1000Genomes | |
| ENSVATH05716875 | 54 | S>C | No | 1000Genomes | |
| ENSVATH05716874 | 57 | G>R | No | 1000Genomes | |
| ENSVATH00274930 | 67 | I>F | No | 1000Genomes | |
| ENSVATH01988241 | 67 | I>M | No | 1000Genomes | |
| ENSVATH05716870 | 68 | V>I | No | 1000Genomes | |
| tmp_2_18406569_C_T | 71 | R>Q | No | 1000Genomes | |
| tmp_2_18406567_G_A | 72 | P>S | No | 1000Genomes | |
| tmp_2_18406552_G_A | 77 | L>F | No | 1000Genomes | |
| tmp_2_18406544_C_G | 79 | K>N | No | 1000Genomes | |
| ENSVATH00274929 | 87 | N>Y | No | 1000Genomes | |
| ENSVATH13638547 | 103 | L>F | No | 1000Genomes | |
| tmp_2_18406372_T_C | 110 | D>G | No | 1000Genomes | |
| ENSVATH05716866 | 114 | R>* | No | 1000Genomes | |
| ENSVATH13638546 | 123 | S>F | No | 1000Genomes | |
| ENSVATH05716865 | 126 | P>S | No | 1000Genomes | |
| ENSVATH14615113 | 135 | N>K | No | 1000Genomes | |
| tmp_2_18406168_C_G | 150 | V>L | No | 1000Genomes | |
| ENSVATH01988228 | 152 | V>I | No | 1000Genomes | |
| tmp_2_18406159_C_T | 153 | E>K | No | 1000Genomes | |
| tmp_2_18406036_C_A | 168 | R>L | No | 1000Genomes | |
| tmp_2_18405830_C_T | 197 | A>T | No | 1000Genomes | |
| tmp_2_18405829_G_A | 197 | A>V | No | 1000Genomes | |
| tmp_2_18405820_A_G | 200 | V>A | No | 1000Genomes | |
| tmp_2_18405814_G_C | 202 | P>R | No | 1000Genomes | |
| ENSVATH01988214 | 203 | I>M | No | 1000Genomes | |
| tmp_2_18405692_C_G | 209 | G>A | No | 1000Genomes | |
| ENSVATH05716858 | 210 | V>G | No | 1000Genomes | |
| tmp_2_18405530_C_G | 226 | V>L | No | 1000Genomes | |
| ENSVATH05716850 | 238 | W>R | No | 1000Genomes | |
| tmp_2_18405488_C_G | 240 | G>R | No | 1000Genomes | |
| tmp_2_18405472_G_T | 245 | S>* | No | 1000Genomes | |
| ENSVATH05716849 | 247 | A>V | No | 1000Genomes | |
| ENSVATH01988207 | 256 | M>L | No | 1000Genomes | |
| ENSVATH01988207 | 256 | M>V | No | 1000Genomes | |
| tmp_2_18405403_G_T | 268 | T>N | No | 1000Genomes | |
| ENSVATH05716847 | 271 | D>N | No | 1000Genomes | |
| ENSVATH14615109 | 284 | L>F | No | 1000Genomes | |
| tmp_2_18405236_C_T | 295 | V>I | No | 1000Genomes | |
| tmp_2_18405187_A_G | 311 | I>T | No | 1000Genomes | |
| tmp_2_18405185_C_T | 312 | E>K | No | 1000Genomes | |
| tmp_2_18405172_C_T | 316 | R>K | No | 1000Genomes | |
| tmp_2_18405164_C_G | 319 | D>H | No | 1000Genomes | |
| ENSVATH13638493 | 323 | R>K | No | 1000Genomes | |
| tmp_2_18405035_G_T,A | 334 | Y>* | No | 1000Genomes | |
| tmp_2_18404995_T_C | 348 | K>E | No | 1000Genomes | |
| ENSVATH00274924 | 362 | Y>C | No | 1000Genomes | |
| ENSVATH05716841 | 363 | G>R | No | 1000Genomes | |
| ENSVATH05716840 | 375 | K>N | No | 1000Genomes | |
| tmp_2_18404809_A_G | 378 | F>S | No | 1000Genomes | |
| ENSVATH13638491 | 381 | H>Y | No | 1000Genomes | |
| ENSVATH00274923 | 384 | L>M | No | 1000Genomes | |
| ENSVATH00274922 | 385 | Q>H | No | 1000Genomes | |
| tmp_2_18404785_C_T | 386 | S>N | No | 1000Genomes | |
| tmp_2_18404699_A_T | 415 | S>T | No | 1000Genomes | |
| ENSVATH01988195 | 423 | A>S | No | 1000Genomes | |
| ENSVATH01988191 | 432 | L>F | No | 1000Genomes | |
| ENSVATH05716838 | 437 | L>F | No | 1000Genomes | |
| ENSVATH05716837 | 439 | R>G | No | 1000Genomes | |
| tmp_2_18404539_G_A | 443 | A>V | No | 1000Genomes | |
| ENSVATH05716834 | 449 | K>N | No | 1000Genomes | |
| tmp_2_18404414_C_T | 460 | A>T | No | 1000Genomes | |
| ENSVATH01988188 | 467 | D>E | No | 1000Genomes | |
| tmp_2_18404365_G_A | 476 | S>L | No | 1000Genomes | |
| ENSVATH05716833 | 497 | H>Q | No | 1000Genomes | |
| ENSVATH05716831 | 501 | Q>E | No | 1000Genomes | |
| ENSVATH14615108 | 508 | P>A | No | 1000Genomes | |
| ENSVATH01988186 | 510 | S>A | No | 1000Genomes | |
| ENSVATH01988184 | 511 | A>T | No | 1000Genomes | |
| ENSVATH13638485 | 536 | E>G | No | 1000Genomes | |
| tmp_2_18404170_G_T | 541 | T>N | No | 1000Genomes | |
| ENSVATH00274917 | 544 | K>M | No | 1000Genomes | |
| ENSVATH01988181 | 547 | V>I | No | 1000Genomes | |
| tmp_2_18404126_G_C | 556 | L>V | No | 1000Genomes | |
| ENSVATH01988178 | 564 | A>T | No | 1000Genomes | |
| ENSVATH13638474 | 569 | S>C | No | 1000Genomes | |
| ENSVATH14615107 | 570 | Q>P | No | 1000Genomes | |
| ENSVATH01988177 | 573 | R>Q | No | 1000Genomes | |
| ENSVATH13638472 | 580 | E>D | No | 1000Genomes | |
| tmp_2_18403950_G_A | 582 | P>L | No | 1000Genomes | |
| tmp_2_18403930_T_A | 589 | M>L | No | 1000Genomes | |
| ENSVATH00274915 | 594 | R>S | No | 1000Genomes | |
| tmp_2_18403900_T_A | 599 | K>* | No | 1000Genomes |
No associated diseases with Q8S3C9
7 regional properties for Q8S3C9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Dynamin stalk domain | 222 - 490 | IPR000375 |
| domain | Dynamin, GTPase domain | 1 - 301 | IPR001401 |
| domain | Dynamin GTPase effector | 515 - 608 | IPR003130 |
| conserved_site | Dynamin, GTPase region, conserved site | 61 - 70 | IPR019762 |
| domain | GTPase effector domain | 520 - 612 | IPR020850 |
| domain | Dynamin-type guanine nucleotide-binding (G) domain | 32 - 301 | IPR030381 |
| domain | Dynamin, N-terminal | 38 - 213 | IPR045063 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
| microtubule | Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
| microtubule binding | Binding to a microtubule, a filament composed of tubulin monomers. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
10 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| O00429 | DNM1L | Dynamin-1-like protein | Homo sapiens (Human) | PR |
| Q05193 | DNM1 | Dynamin-1 | Homo sapiens (Human) | PR |
| Q9UQ16 | DNM3 | Dynamin-3 | Homo sapiens (Human) | PR |
| P39053 | Dnm1 | Dynamin-1 | Mus musculus (Mouse) | PR |
| Q8BZ98 | Dnm3 | Dynamin-3 | Mus musculus (Mouse) | PR |
| Q8K1M6 | Dnm1l | Dynamin-1-like protein | Mus musculus (Mouse) | PR |
| O35303 | Dnm1l | Dynamin-1-like protein | Rattus norvegicus (Rat) | PR |
| P21575 | Dnm1 | Dynamin-1 | Rattus norvegicus (Rat) | PR |
| Q08877 | Dnm3 | Dynamin-3 | Rattus norvegicus (Rat) | PR |
| Q8LF21 | DRP1C | Phragmoplastin DRP1C | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MESLIVLINT | IQRACTVVGD | HGGDSNALSS | LWEALPSVAV | VGGQSSGKSS | VLESIVGRDF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LPRGSGIVTR | RPLVLQLHKT | ENGTEDNAEF | LHLTNKKFTN | FSLVRKEIED | ETDRITGKNK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QISSIPIHLS | IFSPNVVNLT | LIDLPGLTKV | AVEGQPETIV | EDIESMVRSY | VEKPNCLILA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ISPANQDIAT | SDAMKLAKEV | DPIGDRTFGV | LTKLDLMDKG | TNALDVINGR | SYKLKYPWVG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| IVNRSQADIN | KNVDMMVARR | KEREYFETSP | DYGHLATRMG | SEYLAKLLSK | LLESVIRSRI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PSILSLINNN | IEELERELDQ | LGRPIAIDAG | AQLYTILGMC | RAFEKIFKEH | LDGGRPGGAR |
| 370 | 380 | 390 | 400 | 410 | 420 |
| IYGIFDYNLP | TAIKKLPFDR | HLSLQSVKRI | VSESDGYQPH | LIAPELGYRR | LIEGSLNHFR |
| 430 | 440 | 450 | 460 | 470 | 480 |
| GPAEASVNAI | HLILKELVRK | AIAETEELKR | FPSLQIELVA | AANSSLDKFR | EESMKSVLRL |
| 490 | 500 | 510 | 520 | 530 | 540 |
| VDMESSYLTV | DFFRKLHVES | QNMSLSSPTS | AIDQYGDGHF | RKIASNVAAY | IKMVAETLVN |
| 550 | 560 | 570 | 580 | 590 | 600 |
| TIPKAVVHCQ | VRQAKLSLLN | YFYAQISQSQ | GKRLGQLLDE | NPALMERRMQ | CAKRLELYKK |
| 610 | |||||
| ARDEIDAAVW | VR |