Q8R2M0

PR
Gene name
Tceanc2 (Tdeanc2)
Protein name
Transcription elongation factor A N-terminal and central domain-containing protein 2
Names
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:66526
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

84-159 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8R2M0

Entry ID Method Resolution Chain Position Source
AF-Q8R2M0-F1 Predicted AlphaFoldDB

7 variants for Q8R2M0

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3388691591 8 T>M No EVA
rs3388699895 16 K>N No EVA
rs3388704038 32 L>F No EVA
rs28308024 47 M>T No EVA
rs3388698664 131 R>G No EVA
rs3388704001 190 Q>H No EVA
rs3388678190 202 V>G No EVA

No associated diseases with Q8R2M0

2 regional properties for Q8R2M0

Type Name Position InterPro Accession
domain RAD50, zinc hook 630 - 726 IPR013134
domain Rad50/SbcC-type AAA domain 6 - 246 IPR038729

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.

7 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
A5PKE4 TCEANC2 Transcription elongation factor A N-terminal and central domain-containing protein 2 Bos taurus (Bovine) PR
P23193 TCEA1 Transcription elongation factor A protein 1 Homo sapiens (Human) PR
Q96MN5 TCEANC2 Transcription elongation factor A N-terminal and central domain-containing protein 2 Homo sapiens (Human) PR
P23881 Tcea3 Transcription elongation factor A protein 3 Mus musculus (Mouse) PR
P10711 Tcea1 Transcription elongation factor A protein 1 Mus musculus (Mouse) PR
Q5XIC7 Tceanc2 Transcription elongation factor A N-terminal and central domain-containing protein 2 Rattus norvegicus (Rat) PR
P52652 T24H10.1 Putative transcription elongation factor S-II Caenorhabditis elegans PR
10 20 30 40 50 60
MDKFVIRTPR IQNSPKKKLG EKVYKQATIE SLKRVVVIED IKRWKTMLEL PDQTKENLVA
70 80 90 100 110 120
ALQELKKKMP SREVLRSTRI GHAVNKMRRH SDPEVAGLAK EVYTEWKTFI EKHLDRPSIE
130 140 150 160 170 180
VRSDPKTESF RKNAQKLLSE ALELKMDHLL VENIERETFH LCSRLINGPY RRTVRALVFT
190 200
LKHRAEIREQ VKSGALPVGT FVQTHKK