A5PKE4

PR
Gene name
TCEANC2
Protein name
Transcription elongation factor A N-terminal and central domain-containing protein 2
Names
Species
Bos taurus (Bovine)
KEGG Pathway
bta:539385
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

83-164 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A5PKE4

Entry ID Method Resolution Chain Position Source
AF-A5PKE4-F1 Predicted AlphaFoldDB

No variants for A5PKE4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A5PKE4

No associated diseases with A5PKE4

3 regional properties for A5PKE4

Type Name Position InterPro Accession
domain Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type 38 - 113 IPR003617
domain Transcription elongation factor S-II, central domain 131 - 208 IPR003618
domain Transcription factor IIS, N-terminal 40 - 114 IPR017923

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.

7 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P23193 TCEA1 Transcription elongation factor A protein 1 Homo sapiens (Human) PR
Q96MN5 TCEANC2 Transcription elongation factor A N-terminal and central domain-containing protein 2 Homo sapiens (Human) PR
P23881 Tcea3 Transcription elongation factor A protein 3 Mus musculus (Mouse) PR
P10711 Tcea1 Transcription elongation factor A protein 1 Mus musculus (Mouse) PR
Q8R2M0 Tceanc2 Transcription elongation factor A N-terminal and central domain-containing protein 2 Mus musculus (Mouse) PR
Q5XIC7 Tceanc2 Transcription elongation factor A N-terminal and central domain-containing protein 2 Rattus norvegicus (Rat) PR
P52652 T24H10.1 Putative transcription elongation factor S-II Caenorhabditis elegans PR
10 20 30 40 50 60
MDKFVIRTPR IQSSPQKKDP GGKIYKQATI ESLKRVVVIE DIKRWKTMLE LPDQSKENLV
70 80 90 100 110 120
EALRELKKKI PSREVLKSTK IGHTVNKMRQ HSDSEVACLA REVYTEWRTF IEKHVNRPSI
130 140 150 160 170 180
EVRSDAKTET FRKNAQKLLS EALELEMDHL LVENIERETF HLCSRLINGP YRRTVRALVF
190 200
TLKHRAEIRE QVKSGMLPVG TFVQTHKK