Q8N4B4
PR
Gene name |
FBXO39 (FBX39) |
Protein name |
F-box only protein 39 |
Names |
|
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:162517 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8N4B4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8N4B4-F1 | Predicted | AlphaFoldDB |
389 variants for Q8N4B4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
CA8332341 rs61753286 |
2 | D>E | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs143419082 CA8332340 |
2 | D>N | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs368045455 CA8332343 |
3 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA397758491 rs1456666166 |
4 | E>G | No |
ClinGen TOPMed gnomAD |
|
|
CA287393382 rs146724926 |
6 | E>A | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA8332344 rs146724926 |
6 | E>G | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA8332345 rs61753143 |
8 | I>F | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA397758517 rs1198007311 |
8 | I>T | No |
ClinGen TOPMed gnomAD |
|
|
CA397758515 rs61753143 |
8 | I>V | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA397758529 rs4796555 |
10 | P>A | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
VAR_024444 rs4796555 CA8332346 |
10 | P>S | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA8332347 rs770428705 |
11 | Q>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8332348 rs778419218 |
12 | D>H | No |
ClinGen ExAC |
|
|
rs749711767 CA8332350 |
14 | S>I | No |
ClinGen ExAC gnomAD |
|
|
rs749711767 CA8332349 |
14 | S>N | No |
ClinGen ExAC gnomAD |
|
|
CA8332351 rs774739920 |
15 | C>F | No |
ClinGen ExAC gnomAD |
|
|
CA287393399 rs887378122 |
16 | W>* | No |
ClinGen TOPMed |
|
|
CA8332352 rs759700825 |
17 | A>T | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 20 | P>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs78983367 CA8332355 |
21 | D>N | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs78983367 CA8332356 |
21 | D>Y | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs146370414 CA8332357 |
25 | C>R | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA397758736 rs1275816440 |
26 | R>C | No |
ClinGen TOPMed gnomAD |
|
|
rs150934591 CA8332358 |
26 | R>H | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs150934591 CA397758739 |
26 | R>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1597774462 CA397758860 |
33 | D>N | No |
ClinGen Ensembl |
|
|
rs1367304910 CA397758876 |
34 | R>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs766116765 CA8332359 |
35 | D>N | No |
ClinGen ExAC gnomAD |
|
|
CA287393425 rs964089461 |
37 | S>F | No |
ClinGen TOPMed gnomAD |
|
|
CA397758921 rs1323632761 |
37 | S>P | No |
ClinGen gnomAD |
|
|
rs576606128 CA8332363 |
42 | V>G | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs780924976 CA8332362 |
42 | V>L | No |
ClinGen ExAC gnomAD |
|
|
CA397759034 rs1487372888 |
43 | C>F | No |
ClinGen gnomAD |
|
|
CA397759029 rs1487372888 |
43 | C>Y | No |
ClinGen gnomAD |
|
|
rs1228550171 CA397759097 |
46 | W>C | No |
ClinGen TOPMed gnomAD |
|
|
rs1189760384 CA397759123 |
47 | N>K | No |
ClinGen TOPMed gnomAD |
|
|
CA397759189 rs1319738131 |
50 | M>T | No |
ClinGen gnomAD |
|
|
rs542378940 CA287393438 |
51 | Y>H | No |
ClinGen 1000Genomes |
|
|
CA8332365 rs778465960 |
53 | A>T | No |
ClinGen ExAC |
|
|
rs749792809 CA8332366 |
53 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs973567392 CA287393446 |
56 | W>* | No |
ClinGen TOPMed |
|
|
CA8332367 rs200419578 |
57 | R>G | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA397759297 rs140674090 |
57 | R>P | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA8332370 rs140674090 |
57 | R>Q | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA8332369 rs200419578 |
57 | R>W | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs369991116 CA8332371 |
60 | T>I | No |
ClinGen ESP ExAC gnomAD |
|
|
CA287393454 rs376499600 |
61 | I>V | No |
ClinGen Ensembl |
|
|
rs762819097 CA8332375 |
65 | G>E | No |
ClinGen ExAC gnomAD |
|
|
CA8332374 rs776729788 |
65 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8332376 rs766279425 |
67 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs769937090 CA287393456 |
70 | V>L | No |
ClinGen Ensembl |
|
|
CA8332378 rs774019882 |
71 | H>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1363430426 CA397759524 |
71 | H>R | No |
ClinGen gnomAD |
|
|
CA8332379 rs759399371 |
74 | E>A | No |
ClinGen ExAC gnomAD |
|
|
rs1223419376 CA397759576 |
75 | V>A | No |
ClinGen TOPMed gnomAD |
|
|
CA8332380 rs199871206 |
75 | V>F | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA397759568 rs199871206 |
75 | V>I | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA397759585 rs1294244730 |
76 | E>G | No |
ClinGen gnomAD |
|
|
rs1193176007 CA397759623 |
79 | V>A | No |
ClinGen TOPMed gnomAD |
|
|
rs752366449 CA8332381 |
79 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1211818164 CA397759642 |
80 | W>C | No |
ClinGen TOPMed |
|
|
rs564185783 CA397759636 |
80 | W>L | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA8332382 rs564185783 |
80 | W>S | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA8332383 rs763720404 |
81 | Y>H | No |
ClinGen ExAC gnomAD |
|
|
CA8332384 rs1555552099 |
82 | V>I | No |
ClinGen Ensembl |
|
|
rs1187619371 CA397759727 |
86 | G>R | No |
ClinGen TOPMed gnomAD |
|
|
CA287393466 rs1055114273 |
86 | G>V | No |
ClinGen gnomAD |
|
|
CA8332386 rs753332309 |
87 | R>C | No |
ClinGen ExAC gnomAD |
|
|
CA8332387 rs150271375 COSM179541 |
87 | R>H | large_intestine [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD |
|
rs373018115 CA397759786 CA397759784 |
90 | E>D | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs556849207 CA287393478 |
90 | E>K | No |
ClinGen TOPMed |
|
|
rs780290851 CA8332391 |
92 | L>P | No |
ClinGen ExAC gnomAD |
|
|
rs758744565 CA8332390 |
92 | L>V | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 93 | E>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1346518948 CA397759815 |
93 | E>Q | No |
ClinGen gnomAD |
|
| TCGA novel | 93 | E>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA8332392 rs747260135 |
95 | K>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1360540386 CA397759871 |
97 | M>L | No |
ClinGen TOPMed |
|
|
CA287393484 rs991454223 |
98 | N>D | No |
ClinGen TOPMed gnomAD |
|
|
rs569543359 CA8332394 |
99 | P>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1352685189 CA624859726 |
100 | Y>* | No |
ClinGen gnomAD |
|
|
CA8332395 rs748190539 |
101 | N>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1184929110 CA397759957 |
102 | A>V | No |
ClinGen TOPMed |
|
|
rs770840323 CA8332396 |
105 | T>A | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 107 | K>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA397760028 rs1484321910 |
108 | F>I | No |
ClinGen TOPMed |
|
|
rs1237446447 CA397760047 |
109 | Q>* | No |
ClinGen gnomAD |
|
|
CA397760054 rs1482587217 |
109 | Q>H | No |
ClinGen gnomAD |
|
|
rs377353189 CA8332398 |
109 | Q>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA8332399 rs200968555 |
110 | V>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA397760093 COSM1206838 rs1439472363 |
112 | M>I | large_intestine [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
CA8332400 rs775377350 |
112 | M>T | No |
ClinGen ExAC gnomAD |
|
|
rs1317574379 CA397760083 |
112 | M>V | No |
ClinGen TOPMed |
|
|
CA8332402 rs763737793 |
113 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8332401 rs373411596 |
113 | R>W | Variant assessed as Somatic; 4.62e-05 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs1030033745 CA287393510 |
114 | G>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
CA8332403 rs753360062 |
115 | L>F | No |
ClinGen ExAC gnomAD |
|
|
CA8332404 rs756781541 |
116 | L>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8332406 rs138977169 |
117 | S>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA8332405 rs138977169 |
117 | S>Y | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA8332407 rs758859170 |
118 | C>R | No |
ClinGen ExAC gnomAD |
|
|
CA397760184 rs1452655136 |
121 | K>N | No |
ClinGen TOPMed |
|
|
CA8332410 rs747313581 |
122 | S>G | No |
ClinGen ExAC gnomAD |
|
|
rs755195237 CA8332411 |
124 | N>D | No |
ClinGen ExAC gnomAD |
|
|
CA8332412 rs781471298 |
124 | N>K | No |
ClinGen ExAC gnomAD |
|
|
CA287393526 rs889703951 |
125 | R>C | No |
ClinGen TOPMed |
|
|
CA397760224 rs889703951 |
125 | R>G | No |
ClinGen TOPMed |
|
|
rs200344565 CA8332413 |
125 | R>H | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs769894791 CA8332414 |
126 | L>V | No |
ClinGen ExAC gnomAD |
|
|
rs1206201359 CA397760271 |
129 | L>F | No |
ClinGen gnomAD |
|
|
rs1597774688 CA397760281 |
130 | S>P | No |
ClinGen Ensembl |
|
|
CA397760293 rs1244209960 |
131 | I>F | No |
ClinGen TOPMed gnomAD |
|
|
rs1244209960 CA397760292 |
131 | I>V | No |
ClinGen TOPMed gnomAD |
|
|
rs1457607890 CA397760307 |
132 | Q>E | No |
ClinGen gnomAD |
|
|
rs1457607890 CA397760305 |
132 | Q>K | No |
ClinGen gnomAD |
|
|
rs1166377762 CA397760338 |
134 | L>V | No |
ClinGen TOPMed |
|
|
rs1567670837 CA397760344 |
135 | E>K | No |
ClinGen Ensembl |
|
|
rs139725230 CA8332415 |
138 | R>C | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs536953500 CA8332416 |
138 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
rs536953500 CA397760392 |
138 | R>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA8332417 rs1555552120 |
140 | V>I | No |
ClinGen Ensembl |
|
|
rs1470667601 CA397760421 |
141 | W>* | No |
ClinGen gnomAD |
|
|
rs772078290 CA8332419 |
141 | W>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA397760442 rs1486326990 |
142 | R>S | No |
ClinGen TOPMed |
|
|
rs1177085220 CA397760453 |
143 | N>S | No |
ClinGen gnomAD |
|
|
rs1399396548 CA397760488 |
145 | I>M | No |
ClinGen gnomAD |
|
|
CA397760509 rs1444347296 |
147 | S>N | No |
ClinGen gnomAD |
|
|
CA8332420 rs775432290 |
151 | S>C | No |
ClinGen ExAC gnomAD |
|
|
CA287393537 rs1025359121 |
152 | S>I | No |
ClinGen Ensembl |
|
|
CA287393541 rs759206032 |
154 | S>R | No |
ClinGen TOPMed |
|
|
rs199763057 CA8332423 |
155 | F>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA397760618 rs199763057 |
155 | F>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA397760622 rs1321517465 |
156 | F>L | No |
ClinGen gnomAD |
|
|
CA397760642 rs928232682 |
158 | K>N | No |
ClinGen TOPMed |
|
|
rs1009302010 CA287393544 |
158 | K>R | No |
ClinGen TOPMed gnomAD |
|
|
rs375015434 CA8332424 |
159 | K>N | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA397760652 rs1317799694 |
160 | M>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1317799694 CA397760654 |
160 | M>V | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 162 | K>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA8332427 rs147096286 |
163 | R>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA8332428 rs138467906 |
163 | R>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA397760727 rs1393176123 |
165 | D>A | No |
ClinGen TOPMed |
|
|
CA397760721 rs1438073990 |
165 | D>Y | No |
ClinGen TOPMed |
|
|
VAR_049050 CA8332429 rs16956264 |
166 | Y>C | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA397760740 rs16956264 |
166 | Y>F | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA8332430 rs751985308 |
168 | N>T | No |
ClinGen ExAC gnomAD |
|
|
CA397760775 rs1183215986 |
169 | L>Q | No |
ClinGen gnomAD |
|
|
CA287393559 rs915258169 |
170 | K>R | No |
ClinGen TOPMed gnomAD |
|
|
CA397760805 rs1422245000 |
171 | G>A | No |
ClinGen gnomAD |
|
|
CA397760803 rs1422245000 |
171 | G>E | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
| TCGA novel | 172 | A>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs752994888 CA8332433 |
172 | A>T | No |
ClinGen ExAC gnomAD |
|
|
rs1169564645 CA397760828 |
173 | R>G | No |
ClinGen TOPMed gnomAD |
|
|
CA397760841 rs1468071224 |
173 | R>S | No |
ClinGen TOPMed |
|
|
CA8332435 rs148718442 |
176 | V>M | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1343824610 CA397761017 |
182 | I>N | No |
ClinGen gnomAD |
|
|
CA8332438 rs772204934 COSM1661823 |
184 | D>N | kidney [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
rs1226427560 CA397761110 |
187 | S>T | No |
ClinGen TOPMed |
|
|
CA397761121 rs1339910521 |
188 | Y>H | No |
ClinGen gnomAD |
|
|
rs1272426771 CA397761148 |
189 | M>L | No |
ClinGen TOPMed gnomAD |
|
|
rs780129786 CA8332439 |
189 | M>T | No |
ClinGen ExAC gnomAD |
|
|
rs1272426771 CA397761146 |
189 | M>V | No |
ClinGen TOPMed gnomAD |
|
|
rs768471007 CA8332441 |
192 | E>K | No |
ClinGen ExAC gnomAD |
|
|
CA397761287 rs1222740488 |
194 | V>M | No |
ClinGen gnomAD |
|
|
CA8332443 rs200840096 |
195 | I>F | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs761545468 CA8332444 |
195 | I>M | No |
ClinGen ExAC gnomAD |
|
|
CA397761370 rs1426211952 |
198 | L>V | No |
ClinGen gnomAD |
|
|
rs755675137 CA397761409 |
200 | I>N | No |
ClinGen gnomAD |
|
|
CA287393593 rs755675137 |
200 | I>T | No |
ClinGen gnomAD |
|
|
CA8332446 COSM244474 rs546513446 |
201 | E>K | prostate [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
rs762444514 CA8332448 |
202 | D>V | No |
ClinGen ExAC gnomAD |
|
|
CA8332449 rs766928241 |
203 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
CA397761474 rs1288183802 |
203 | Y>H | No |
ClinGen Ensembl |
|
|
CA397761512 rs1446841473 |
204 | F>S | No |
ClinGen gnomAD |
|
|
CA8332450 rs200058448 |
205 | S>T | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1567670943 CA397761555 |
206 | H>Y | No |
ClinGen Ensembl |
|
|
CA8332452 rs767947605 |
209 | A>S | No |
ClinGen ExAC gnomAD |
|
|
rs1388969710 CA397761608 |
210 | V>I | No |
ClinGen TOPMed |
|
|
CA397761627 rs1394968378 |
211 | Y>C | No |
ClinGen TOPMed |
|
|
CA397761648 rs1298170830 |
212 | N>I | No |
ClinGen TOPMed |
|
|
CA397761663 rs1244658497 |
213 | S>N | No |
ClinGen gnomAD |
|
|
CA8332454 rs752947385 |
213 | S>R | No |
ClinGen ExAC gnomAD |
|
|
CA397761701 CA397761700 rs1246341334 |
215 | Q>H | No |
ClinGen gnomAD |
|
|
CA397761694 rs1430787481 |
215 | Q>R | No |
ClinGen TOPMed |
|
|
CA8332456 rs778139105 |
216 | F>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8332457 rs754032139 |
220 | M>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs4143218 CA8332458 VAR_049051 |
221 | S>T | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA8332460 rs372175030 |
223 | F>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA8332461 rs372175030 |
223 | F>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1386926679 CA397761860 |
225 | N>S | No |
ClinGen gnomAD |
|
|
CA287393626 rs11655689 |
227 | V>E | No |
ClinGen Ensembl |
|
|
CA287393623 rs1006782914 |
227 | V>L | No |
ClinGen Ensembl |
|
|
CA397761905 rs1445015921 |
228 | S>F | No |
ClinGen gnomAD |
|
|
CA397761934 rs1220857034 |
230 | N>S | No |
ClinGen TOPMed gnomAD |
|
|
VAR_024445 CA8332463 rs1509123 |
231 | L>F | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA287393632 rs1509123 |
231 | L>I | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA8332464 rs769558510 |
231 | L>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8332465 rs769558510 |
231 | L>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs941531074 CA287393640 |
234 | N>T | No |
ClinGen TOPMed |
|
|
CA397762020 rs1327453247 |
236 | I>F | No |
ClinGen Ensembl |
|
|
CA397762045 rs1396018323 |
237 | S>F | No |
ClinGen gnomAD |
|
|
rs773802168 COSM1206836 CA8332468 |
238 | D>N | large_intestine [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
CA397762081 rs1333535550 |
239 | E>D | No |
ClinGen TOPMed |
|
|
rs767844011 CA8332470 |
239 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA397762083 rs1306885025 |
240 | L>M | No |
ClinGen TOPMed |
|
|
CA397762150 rs1314726818 |
244 | L>S | No |
ClinGen gnomAD |
|
|
COSM983445 rs369101262 CA287393649 |
245 | C>Y | Variant assessed as Somatic; impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP NCI-TCGA TOPMed |
|
CA397762177 rs1240711845 |
246 | E>K | No |
ClinGen gnomAD |
|
|
CA397762196 rs932927041 |
247 | N>H | No |
ClinGen TOPMed gnomAD |
|
|
rs932927041 CA287393651 |
247 | N>Y | No |
ClinGen TOPMed gnomAD |
|
|
CA397762230 rs1434279104 |
251 | L>H | No |
ClinGen TOPMed |
|
|
rs200692290 CA8332474 |
252 | R>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA8332473 rs764456683 |
252 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA8332475 rs201661413 |
255 | N>T | No |
ClinGen 1000Genomes ExAC gnomAD |
|
| TCGA novel | 256 | I>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs750415033 CA8332477 |
257 | K>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8332478 rs200096915 |
258 | C>R | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs780990747 CA8332479 |
259 | H>Y | No |
ClinGen ExAC gnomAD |
|
|
CA397762282 rs114913476 |
260 | V>F | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA8332481 COSM1385614 RCV000959341 rs114913476 |
260 | V>I | large_intestine [Cosmic] | No |
ClinGen cosmic curated ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
CA287393671 rs991077799 |
263 | P>H | No |
ClinGen TOPMed gnomAD |
|
|
CA397762305 rs1408872260 |
263 | P>S | No |
ClinGen gnomAD |
|
|
CA287393673 rs375399858 CA397762314 |
264 | H>Q | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA8332484 rs770512910 |
265 | G>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8332483 rs202030641 |
265 | G>R | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
rs773855285 CA8332485 |
266 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
rs745363712 CA8332486 |
266 | Q>H | No |
ClinGen ExAC gnomAD |
|
|
rs865974781 CA287393680 |
269 | W>* | No |
ClinGen Ensembl |
|
|
CA8332487 rs772690535 |
270 | G>D | No |
ClinGen ExAC gnomAD |
|
|
rs772690535 CA397762350 |
270 | G>V | No |
ClinGen ExAC gnomAD |
|
|
rs1197910422 CA397762360 |
272 | S>T | No |
ClinGen gnomAD |
|
|
rs1567671063 CA397762380 |
274 | A>V | No |
ClinGen Ensembl |
|
|
rs978110759 CA287393686 |
275 | K>* | No |
ClinGen gnomAD |
|
|
rs1330491304 CA397762388 |
276 | L>M | No |
ClinGen gnomAD |
|
|
rs1291748807 CA397762397 |
277 | A>G | No |
ClinGen TOPMed |
|
|
rs183581445 CA8332493 |
278 | R>M | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA8332494 rs144312029 |
279 | Q>E | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs750586807 CA8332495 |
282 | N>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA397762448 rs1431508802 |
285 | V>A | No |
ClinGen gnomAD |
|
|
CA397762449 rs1431508802 |
285 | V>G | No |
ClinGen gnomAD |
|
|
CA8332498 rs528227620 |
286 | N>K | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1336379858 CA397762453 |
286 | N>T | No |
ClinGen TOPMed |
|
|
rs752546854 CA8332499 |
287 | F>L | No |
ClinGen ExAC gnomAD |
|
|
CA287393698 rs561955531 |
288 | F>L | No |
ClinGen Ensembl |
|
|
rs372299377 CA8332500 |
288 | F>L | No |
ClinGen ESP ExAC gnomAD |
|
|
CA8332501 rs200774821 |
289 | F>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA397762472 rs1160034969 |
289 | F>V | No |
ClinGen TOPMed |
|
|
CA8332503 rs756968972 |
291 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
CA8332502 rs149057361 |
291 | R>W | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA397762500 rs1345578429 |
293 | M>R | No |
ClinGen gnomAD |
|
|
CA8332505 rs142087585 |
294 | K>M | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA8332504 rs142087585 |
294 | K>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs779573380 CA8332507 |
296 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs747537634 CA8332508 COSM983451 |
297 | R>C | endometrium [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
CA8332509 rs769232319 |
297 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8332511 rs200974896 |
299 | A>S | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA8332512 rs770201697 |
300 | R>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs770201697 CA8332513 |
300 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8332514 rs558767788 |
300 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs1186451312 CA397762560 |
303 | L>S | No |
ClinGen gnomAD |
|
|
rs766401032 CA8332515 |
304 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
rs1430686956 CA397762572 |
305 | E>K | No |
ClinGen gnomAD |
|
|
CA8332516 rs751609367 |
306 | I>F | No |
ClinGen ExAC gnomAD |
|
|
rs536666264 CA8332517 |
307 | P>A | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA397762587 rs1422424409 |
307 | P>L | No |
ClinGen gnomAD |
|
|
rs536666264 CA397762585 |
307 | P>T | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA397762591 rs1597775110 |
308 | I>F | No |
ClinGen Ensembl |
|
|
rs373266699 CA8332519 |
309 | R>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs757022078 CA8332520 |
311 | I>V | No |
ClinGen ExAC gnomAD |
|
|
CA397762677 rs778665808 |
314 | R>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8332521 rs778665808 |
314 | R>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8332522 rs750071463 |
314 | R>S | No |
ClinGen ExAC gnomAD |
|
|
rs758016899 CA8332523 |
315 | S>G | No |
ClinGen ExAC gnomAD |
|
|
CA8332524 rs779439278 |
315 | S>R | No |
ClinGen ExAC gnomAD |
|
|
CA397762691 rs1311807573 |
315 | S>T | No |
ClinGen TOPMed gnomAD |
|
|
rs1225459657 CA397762707 |
316 | C>S | No |
ClinGen TOPMed |
|
|
rs1225459657 CA397762710 |
316 | C>Y | No |
ClinGen TOPMed |
|
|
CA397762726 rs1244146159 |
317 | Y>C | No |
ClinGen gnomAD |
|
|
CA8332525 rs746456824 |
322 | D>A | No |
ClinGen ExAC gnomAD |
|
|
CA397762809 rs746456824 |
322 | D>G | No |
ClinGen ExAC gnomAD |
|
|
rs1215099781 CA397762875 |
325 | M>I | No |
ClinGen gnomAD |
|
|
rs376123264 CA8332526 |
325 | M>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1240897962 CA397762893 |
326 | R>I | No |
ClinGen TOPMed gnomAD |
|
|
rs1240897962 CA397762887 |
326 | R>K | No |
ClinGen TOPMed gnomAD |
|
|
rs1487160808 CA397762897 |
326 | R>S | No |
ClinGen gnomAD |
|
|
rs1240897962 CA397762890 |
326 | R>T | No |
ClinGen TOPMed gnomAD |
|
|
CA8332527 rs200108762 |
328 | T>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs200108762 CA397762935 |
328 | T>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA8332530 rs377424506 |
330 | I>L | No |
ClinGen ESP ExAC gnomAD |
|
|
rs1193811495 CA397763027 |
333 | L>M | No |
ClinGen gnomAD |
|
|
CA397763047 rs1346435926 |
334 | P>R | No |
ClinGen gnomAD |
|
|
rs1156360829 CA397763041 |
334 | P>S | No |
ClinGen TOPMed gnomAD |
|
|
rs774361072 CA8332534 |
337 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8332533 rs201119465 |
337 | R>W | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1221424175 CA397763134 |
338 | H>Q | No |
ClinGen TOPMed |
|
|
rs759597076 CA8332535 |
338 | H>R | No |
ClinGen ExAC gnomAD |
|
|
CA397763148 rs1452719497 |
339 | T>I | No |
ClinGen TOPMed |
|
|
CA8332536 rs764065256 |
340 | L>V | No |
ClinGen ExAC gnomAD |
|
|
CA397763185 rs1282316678 |
341 | Q>R | No |
ClinGen gnomAD |
|
| TCGA novel | 343 | L>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA8332557 rs765151090 |
344 | T>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs141897477 CA8332555 |
344 | T>P | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA8332556 rs141897477 |
344 | T>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA397735517 rs765151090 |
344 | T>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1396417549 CA397735519 |
345 | C>R | No |
ClinGen TOPMed |
|
|
CA8332559 rs762799823 |
345 | C>Y | No |
ClinGen ExAC gnomAD |
|
|
CA397735534 rs1342375688 |
347 | F>L | No |
ClinGen gnomAD |
|
|
CA397735542 rs1426551252 |
348 | N>D | No |
ClinGen gnomAD |
|
|
rs370487511 CA8332563 |
348 | N>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA8332562 rs370487511 |
348 | N>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA8332564 rs767159771 |
350 | N>H | No |
ClinGen ExAC gnomAD |
|
|
CA397735559 rs1430973646 |
350 | N>I | No |
ClinGen TOPMed |
|
|
rs1395513019 CA397735572 |
352 | E>* | No |
ClinGen TOPMed gnomAD |
|
|
rs1395513019 CA397735570 |
352 | E>K | No |
ClinGen TOPMed gnomAD |
|
|
rs752196704 CA8332565 |
353 | S>A | No |
ClinGen ExAC gnomAD |
|
|
rs756584502 CA8332566 |
353 | S>L | No |
ClinGen ExAC gnomAD |
|
|
rs1567672363 CA397735584 |
354 | L>V | No |
ClinGen Ensembl |
|
|
rs555381081 CA8332571 COSM1963585 |
355 | D>E | haematopoietic_and_lymphoid_tissue [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC TOPMed gnomAD |
|
rs1597777858 CA397735591 |
355 | D>G | No |
ClinGen Ensembl |
|
|
CA8332569 rs757609993 |
355 | D>N | No |
ClinGen ExAC gnomAD |
|
|
CA397735594 COSM1750265 rs772219882 |
356 | E>* | urinary_tract [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
CA8332572 rs772219882 |
356 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8332573 rs772219882 |
356 | E>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA397735601 rs1225965291 |
357 | E>Q | No |
ClinGen gnomAD |
|
|
rs568654244 CA8332575 |
359 | H>L | No |
ClinGen 1000Genomes ExAC |
|
|
CA397735638 rs17853331 |
362 | I>M | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs762700116 CA8332578 |
363 | I>L | No |
ClinGen ExAC gnomAD |
|
|
rs7213731 CA8332579 VAR_024446 |
363 | I>M | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA8332577 rs762700116 |
363 | I>V | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 365 | C>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA8332581 rs767212969 |
367 | K>R | No |
ClinGen ExAC gnomAD |
|
|
CA8332582 rs752313021 |
369 | F>L | No |
ClinGen ExAC gnomAD |
|
|
CA8332583 rs577479036 COSM4151724 |
371 | F>L | kidney [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC gnomAD |
|
CA397735694 rs1200076502 COSM4151724 |
371 | F>L | kidney [Cosmic] | No |
ClinGen cosmic curated TOPMed gnomAD |
|
CA8332584 rs764547416 |
373 | I>L | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 373 | I>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA397735725 rs1169464830 |
375 | A>S | No |
ClinGen TOPMed gnomAD |
|
|
rs1419935393 CA397735726 |
375 | A>V | No |
ClinGen gnomAD |
|
|
CA8332585 rs189049648 |
376 | F>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1597777925 CA397735754 |
379 | V>G | No |
ClinGen Ensembl |
|
|
CA397735760 rs1299556412 |
380 | S>T | No |
ClinGen TOPMed |
|
|
rs750714939 CA8332589 |
384 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs996532924 CA287360373 |
384 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs1029525785 CA287360394 |
388 | S>N | No |
ClinGen TOPMed gnomAD |
|
|
rs1289063658 CA397735835 |
391 | E>A | No |
ClinGen gnomAD |
|
|
rs142490988 CA8332592 |
392 | R>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA397735841 rs1490703546 |
392 | R>W | No |
ClinGen TOPMed gnomAD |
|
|
rs780245730 CA8332593 |
393 | Q>E | No |
ClinGen ExAC gnomAD |
|
|
rs1252882390 CA397735853 |
394 | C>G | No |
ClinGen TOPMed |
|
|
CA8332594 rs138846870 |
397 | R>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs768752968 CA8332595 |
397 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA397735876 rs1213197128 |
398 | V>L | No |
ClinGen TOPMed |
|
|
COSM179547 CA8332642 rs761295686 |
401 | A>V | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs765786163 CA8332643 |
403 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs1201666723 CA397735935 |
405 | T>A | No |
ClinGen gnomAD |
|
|
rs775749801 CA8332645 |
407 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs766792237 CA397735950 |
407 | R>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs766792237 CA8332646 |
407 | R>K | No |
ClinGen ExAC gnomAD |
|
|
CA287360969 rs946596450 |
408 | Y>* | No |
ClinGen Ensembl |
|
|
CA397735967 rs1201253982 |
409 | E>D | No |
ClinGen gnomAD |
|
|
rs571164016 CA397735971 |
410 | T>K | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs571164016 CA8332647 |
410 | T>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
CA8332649 rs767629010 |
413 | E>K | No |
ClinGen ExAC TOPMed |
|
| TCGA novel | 416 | T>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 418 | Q>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA287360977 rs991629302 |
418 | Q>K | No |
ClinGen TOPMed |
|
|
CA8332650 rs752883493 |
419 | E>* | No |
ClinGen ExAC gnomAD |
|
|
rs1415156164 CA397736038 |
420 | I>V | No |
ClinGen TOPMed |
|
|
CA397736048 rs1567672592 |
421 | Y>C | No |
ClinGen Ensembl |
|
|
CA397736060 rs1297275880 |
423 | K>E | No |
ClinGen TOPMed gnomAD |
|
|
CA8332653 rs368835979 |
425 | R>K | No |
ClinGen ESP ExAC gnomAD |
|
|
rs777960207 CA397736101 |
428 | I>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs775055409 CA8332655 |
429 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA397736102 rs775055409 |
429 | E>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA397736113 rs1221685157 |
430 | S>* | No |
ClinGen gnomAD |
|
|
rs1312578252 CA397736119 |
431 | E>G | No |
ClinGen gnomAD |
|
|
rs1226366407 CA397736125 |
432 | L>F | No |
ClinGen gnomAD |
|
|
rs758349334 CA8332656 |
434 | Y>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA397736144 rs1597778356 |
435 | F>I | No |
ClinGen Ensembl |
|
|
CA8332657 rs779900966 |
435 | F>S | No |
ClinGen ExAC gnomAD |
|
|
rs138472328 CA287361077 COSM109570 |
436 | V>D | skin [Cosmic] | No |
ClinGen cosmic curated Ensembl |
|
CA8332658 rs746771101 |
437 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs776128884 CA8332661 |
438 | V>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8332660 rs776128884 |
438 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA397736162 rs776128884 |
438 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs933927170 CA287361085 |
440 | S>Y | No |
ClinGen gnomAD |
|
|
CA397736183 rs1170243351 |
441 | V>A | No |
ClinGen gnomAD |
|
|
CA397736179 rs1467443356 |
441 | V>M | No |
ClinGen TOPMed |
|
|
rs1371680927 CA397736195 |
443 | M>Q | No |
ClinGen gnomAD |
No associated diseases with Q8N4B4
9 regional properties for Q8N4B4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | F-box domain | 5 - 46 | IPR001810 |
| repeat | Leucine-rich repeat, cysteine-containing subtype | 100 - 124 | IPR006553-1 |
| repeat | Leucine-rich repeat, cysteine-containing subtype | 125 - 150 | IPR006553-2 |
| repeat | Leucine-rich repeat, cysteine-containing subtype | 309 - 332 | IPR006553-3 |
| repeat | Leucine-rich repeat, cysteine-containing subtype | 367 - 391 | IPR006553-4 |
| repeat | Leucine-rich repeat, cysteine-containing subtype | 427 - 450 | IPR006553-5 |
| repeat | Leucine-rich repeat, cysteine-containing subtype | 476 - 500 | IPR006553-6 |
| domain | Transport inhibitor response 1 domain | 62 - 108 | IPR041101 |
| domain | COI1, F-box | 5 - 43 | IPR041567 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| SCF ubiquitin ligase complex | A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1). |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome. |
7 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9UKT7 | FBXL3 | F-box/LRR-repeat protein 3 | Homo sapiens (Human) | PR |
| Q8N461 | FBXL16 | F-box/LRR-repeat protein 16 | Homo sapiens (Human) | PR |
| Q5XUX0 | FBXO31 | F-box only protein 31 | Homo sapiens (Human) | PR |
| Q8C4V4 | Fbxl3 | F-box/LRR-repeat protein 3 | Mus musculus (Mouse) | PR |
| Q8BH70 | Fbxl4 | F-box/LRR-repeat protein 4 | Mus musculus (Mouse) | PR |
| Q9ZR12 | GRH1 | GRR1-like protein 1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LTX2 | At5g49980 | Transport inhibitor response 1-like protein | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDEESELIQP | QDQSCWAFLP | DLCLCRVFWW | LGDRDRSRAA | LVCRKWNQMM | YSAELWRYRT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ITFSGRPSRV | HASEVESAVW | YVKKFGRYLE | HLEVKFMNPY | NAVLTKKFQV | TMRGLLSCLS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KSNNRLKSLS | IQYLELDRLV | WRNSIRSSFI | SSLSFFLKKM | GKRLDYLNLK | GARLTVEQGC |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QILDSLSYMR | NENVISELNI | EDYFSHHLAV | YNSPQFKKTM | STFHNLVSLN | LNYNCISDEL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LENLCENAST | LRTINIKCHV | HDPHGQVIWG | MSWAKLARQA | TNLKVNFFFE | RIMKYERLAR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ILLQEIPIRS | ISLRSCYFSD | PDCSMRPTLI | DLLPTFRHTL | QKLTCEFNNN | HESLDEELHL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LIISCRKLFY | FKIWAFLDVS | FVERILKSQK | ERQCALRVFK | ARIYTNRYET | NEEDKTLQEI |
| 430 | 440 | ||||
| YRKYRKLIES | ELSYFVIVYS | VM |