Q8C525

PR
Gene name
Mb21d2
Protein name
Nucleotidyltransferase MB21D2
Names
Mab-21 domain-containing protein 2
Species
Mus musculus (Mouse)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

339-412 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8C525

Entry ID Method Resolution Chain Position Source
AF-Q8C525-F1 Predicted AlphaFoldDB

No variants for Q8C525

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8C525

No associated diseases with Q8C525

2 regional properties for Q8C525

Type Name Position InterPro Accession
domain Mab-21-like, nucleotidyltransferase domain 90 - 235 IPR046903
domain Mab-21-like, HhH/H2TH-like domain 261 - 337 IPR046906

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
nucleotidyltransferase activity Catalysis of the transfer of a nucleotidyl group to a reactant.
protein-containing complex binding Binding to a macromolecular complex.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
E1BGN7 CGAS Cyclic GMP-AMP synthase Bos taurus (Bovine) PR
Q8N884 CGAS Cyclic GMP-AMP synthase Homo sapiens (Human) PR
Q8C6L5 Cgas Cyclic GMP-AMP synthase Mus musculus (Mouse) PR
I3LM39 CGAS Cyclic GMP-AMP synthase Sus scrofa (Pig) PR
10 20 30 40 50 60
MLQTPMTGMV QKLDQKLPVA NEYLLLSGGV REGVVDLDLD ELNVYARGTD YDMDFTLLVP
70 80 90 100 110 120
ALKLHDRNQP VTLDMRHSAL CHSWLSLRLF DEGTISKWKG CCTIADHING ATNYFFSPTK
130 140 150 160 170 180
VADWFYDSIS IVLSEIQKKP QRGMPKVEKV EKNGTIISII LGVGSSRMLY DIVPVVSFKG
190 200 210 220 230 240
WPAVAQSWLM ENHFWDGKIT EEEVISGFYL VPACSYKGKK DNEWRLSFAR SEVQLKKCIS
250 260 270 280 290 300
GSLMQAYQAC KAIIIKLLSR PKAISPYHLR SMMLWACDRL PASYLAQEDY AAHFLLGLID
310 320 330 340 350 360
DLQHCLVNKM CPNYFIPQCN MLEHLSEETV MLHARKLSSV RSDPAEHLRT AIEHVKAANR
370 380 390 400 410 420
LTLKLQRRGS TTSIPSPQSD GGDPNQPDDR LAKKLQQLVT ENPGKSISVF INPDDVTRPH
FRIDDKFF