Q84P17
PR
Gene name |
AAE18 (At1g55320, F7A10.14) |
Protein name |
Probable acyl-activating enzyme 18, peroxisomal |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G55320 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q84P17
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q84P17-F1 | Predicted | AlphaFoldDB |
61 variants for Q84P17
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH04967959 | 7 | E>Q | No | 1000Genomes | |
| ENSVATH13579389 | 18 | L>M | No | 1000Genomes | |
| ENSVATH00098509 | 62 | P>H | No | 1000Genomes | |
| ENSVATH04967961 | 70 | S>T | No | 1000Genomes | |
| ENSVATH04967962 | 78 | S>F | No | 1000Genomes | |
| tmp_1_20633623_T_A | 85 | Y>N | No | 1000Genomes | |
| tmp_1_20633757_A_G | 100 | K>E | No | 1000Genomes | |
| tmp_1_20633821_T_C | 121 | F>S | No | 1000Genomes | |
| ENSVATH04967965 | 142 | E>D | No | 1000Genomes | |
| ENSVATH04967966 | 163 | T>N | No | 1000Genomes | |
| ENSVATH04967967 | 176 | C>S | No | 1000Genomes | |
| ENSVATH01372899 | 178 | M>L | No | 1000Genomes | |
| tmp_1_20634288_T_A | 219 | V>E | No | 1000Genomes | |
| tmp_1_20634388_A_T | 252 | L>F | No | 1000Genomes | |
| ENSVATH13579405 | 292 | R>L | No | 1000Genomes | |
| ENSVATH14321726 | 293 | R>G | No | 1000Genomes | |
| ENSVATH04967970 | 309 | I>F | No | 1000Genomes | |
| tmp_1_20634751_G_T | 315 | G>C | No | 1000Genomes | |
| ENSVATH01372917 | 319 | H>R | No | 1000Genomes | |
| tmp_1_20634770_A_T | 321 | Q>L | No | 1000Genomes | |
| ENSVATH13579407 | 325 | Q>* | No | 1000Genomes | |
| ENSVATH01372920 | 327 | V>I | No | 1000Genomes | |
| ENSVATH01372920 | 327 | V>L | No | 1000Genomes | |
| ENSVATH01372921 | 330 | M>I | No | 1000Genomes | |
| ENSVATH01372922 | 335 | N>S | No | 1000Genomes | |
| ENSVATH01372924 | 336 | A>V | No | 1000Genomes | |
| tmp_1_20634819_A_C | 337 | K>N | No | 1000Genomes | |
| ENSVATH01372925 | 338 | P>T | No | 1000Genomes | |
| ENSVATH01372927 | 340 | S>F | No | 1000Genomes | |
| ENSVATH01372926 | 340 | S>P | No | 1000Genomes | |
| tmp_1_20634829_A_T | 341 | S>C | No | 1000Genomes | |
| ENSVATH14321728 | 388 | A>V | No | 1000Genomes | |
| ENSVATH14321729 | 393 | Q>E | No | 1000Genomes | |
| ENSVATH00098518 | 396 | H>N | No | 1000Genomes | |
| tmp_1_20635150_C_T | 397 | T>I | No | 1000Genomes | |
| ENSVATH01372935 | 413 | M>I | No | 1000Genomes | |
| ENSVATH00098519 | 427 | S>N | No | 1000Genomes | |
| ENSVATH13579410 | 442 | A>T | No | 1000Genomes | |
| ENSVATH00098520 | 464 | E>K | No | 1000Genomes | |
| ENSVATH00098520 | 464 | E>Q | No | 1000Genomes | |
| ENSVATH04967976 | 482 | N>S | No | 1000Genomes | |
| ENSVATH01372938 | 494 | D>Y | No | 1000Genomes | |
| ENSVATH04967977 | 495 | Y>F | No | 1000Genomes | |
| ENSVATH01372939 | 499 | I>M | No | 1000Genomes | |
| tmp_1_20635677_C_T | 519 | P>L | No | 1000Genomes | |
| ENSVATH00098522 | 545 | P>A | No | 1000Genomes | |
| tmp_1_20635906_C_A | 570 | A>E | No | 1000Genomes | |
| ENSVATH13579425 | 590 | R>K | No | 1000Genomes | |
| tmp_1_20636063_G_T | 592 | G>C | No | 1000Genomes | |
| ENSVATH00098527 | 604 | N>H | No | 1000Genomes | |
| tmp_1_20636114_G_T | 609 | A>S | No | 1000Genomes | |
| ENSVATH00098530 | 620 | T>M | No | 1000Genomes | |
| ENSVATH01372949 | 648 | N>S | No | 1000Genomes | |
| tmp_1_20636327_G_C | 649 | G>R | No | 1000Genomes | |
| ENSVATH14321732 | 656 | I>M | No | 1000Genomes | |
| tmp_1_20636361_T_G | 660 | L>W | No | 1000Genomes | |
| ENSVATH01372950 | 665 | K>T | No | 1000Genomes | |
| ENSVATH00098531 | 669 | G>E | No | 1000Genomes | |
| ENSVATH13579433 | 673 | K>Q | No | 1000Genomes | |
| ENSVATH04967990 | 697 | P>L | No | 1000Genomes | |
| tmp_1_20636649_G_A | 725 | S>N | No | 1000Genomes |
No associated diseases with Q84P17
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| peroxisome | A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| ligase activity | Catalysis of the joining of two molecules, or two groups within a single molecule, using the energy from the hydrolysis of ATP, a similar triphosphate, or a pH gradient. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| auxin metabolic process | The chemical reactions and pathways involving auxins, a group of plant hormones that regulate aspects of plant growth. |
| fatty acid metabolic process | The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis. |
8 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9NR19 | ACSS2 | Acetyl-coenzyme A synthetase, cytoplasmic | Homo sapiens (Human) | PR |
| Q68CK6 | ACSM2B | Acyl-coenzyme A synthetase ACSM2B, mitochondrial | Homo sapiens (Human) | PR |
| Q08AH3 | ACSM2A | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | Homo sapiens (Human) | PR |
| Q9QXG4 | Acss2 | Acetyl-coenzyme A synthetase, cytoplasmic | Mus musculus (Mouse) | PR |
| Q9D2R0 | Aacs | Acetoacetyl-CoA synthetase | Mus musculus (Mouse) | PR |
| Q8K0L3 | Acsm2 | Acyl-coenzyme A synthetase ACSM2, mitochondrial | Mus musculus (Mouse) | PR |
| Q9JMI1 | Aacs | Acetoacetyl-CoA synthetase | Rattus norvegicus (Rat) | PR |
| O70490 | Acsm2 | Acyl-coenzyme A synthetase ACSM2, mitochondrial | Rattus norvegicus (Rat) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MWKSIGELSC | DDYVKAGLTL | EDAKEFDKLV | SDVITKAIET | DPRDQWKALV | DESVLKPWHP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HPLHQLLYYS | VYSNWDSSVH | GPPLYWFPSL | SQSKSTNLGK | LMEYHGPRLL | GPSYKNPLES |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FELFRRFSVE | HPEVYWSFVI | DELSLVFHTP | PRCILNKSKP | EGTWLPDAVL | NIAECCLMPS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SHPKKEDDSV | AVVWRNEGFD | DSPVNRMTIK | ELREQVMLVA | NAISGSFEKG | DTIAIDMPMT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VDAVIIYLAI | ILAGCIVVSI | ADSFAAKEIA | TRLKISKAKG | IFTQDYILRG | GRRFPLYSRV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VEAAPSKVIV | LPASGTELHV | QLREQDVSWM | DFLSNAKPHS | SGENYYRPIY | LPVESVINIL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| FSSGTTGEPK | AIPWTQLSPI | RSACDGWAHL | DVQVGHTYCW | PTNLGWVMGP | TLMFSCFLTG |
| 430 | 440 | 450 | 460 | 470 | 480 |
| ATLALYSGSP | LGRGFGKFVQ | DAGVTVLGTV | PSLVKTWKRT | NCMEGLNWTK | IKFFATTGEA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| SNVDDVLWLS | SKADYKPVIE | CCGGTELASS | YIIGSPLQPQ | AFGAFSTPSM | TTRIIIFDEN |
| 550 | 560 | 570 | 580 | 590 | 600 |
| GVPYPDDQPC | TGEVGLFPQH | LGATDRLLNA | NHDEVYFKGM | PMYKETRLRR | HGDIVKRTVG |
| 610 | 620 | 630 | 640 | 650 | 660 |
| GYYNVQGRAD | DTMNLGGIKT | SSIEIERVCD | QADECISETA | AVTLTPPNGG | PELLVIFAVL |
| 670 | 680 | 690 | 700 | 710 | 720 |
| KEGFKQQSGE | ELKMKFSRTI | QKDLNPLFKV | SFVKIVPEFP | RTASSKLLRR | VLRDQIKQEL |
| LSLRSRI |