Q67XJ2
Gene name |
NFYB10 (At3g53340, F4P12_40) |
Protein name |
Nuclear transcription factor Y subunit B-10 |
Names |
AtNF-YB-10 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G53340 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q67XJ2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q67XJ2-F1 | Predicted | AlphaFoldDB |
8 variants for Q67XJ2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH00417282 | 3 | E>D | No | 1000Genomes | |
| ENSVATH02499499 | 15 | E>D | No | 1000Genomes | |
| ENSVATH12741547 | 107 | D>N | No | 1000Genomes | |
| ENSVATH12741546 | 111 | V>I | No | 1000Genomes | |
| ENSVATH06307472 | 140 | P>S | No | 1000Genomes | |
| ENSVATH12741542 | 141 | S>G | No | 1000Genomes | |
| ENSVATH12741538 | 149 | V>L | No | 1000Genomes | |
| tmp_3_19774687_G_A | 171 | Q>* | No | 1000Genomes |
No associated diseases with Q67XJ2
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| CCAAT-binding factor complex | A heteromeric transcription factor complex that binds to the CCAAT-box upstream of promoters; functions as both an activator and a repressor, depending on its interacting cofactors. Typically trimeric consisting of NFYA, NFYB and NFYC subunits. In Saccharomyces, it activates the transcription of genes in response to growth in a nonfermentable carbon source and consists of four known subunits: HAP2, HAP3, HAP4 and HAP5. |
5 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA-binding transcription activator activity, RNA polymerase II-specific | A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets transcribed by RNA polymerase II. |
| DNA-binding transcription factor activity | A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. |
| DNA-binding transcription factor activity, RNA polymerase II-specific | A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II. |
| protein heterodimerization activity | Binding to a nonidentical protein to form a heterodimer. |
| transcription cis-regulatory region binding | Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| glucosinolate metabolic process | The chemical reactions and pathways involving glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. They are metabolized to a variety of toxic products which are most likely the cause of hepatocytic necrosis in animals and humans. |
| regulation of transcription by RNA polymerase II | Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
4 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q32KW0 | NFYB | Nuclear transcription factor Y subunit beta | Bos taurus (Bovine) | PR |
| Q6RG77 | NFYB | Nuclear transcription factor Y subunit beta | Equus caballus (Horse) | PR |
| O23310 | NFYB3 | Nuclear transcription factor Y subunit B-3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8VYK4 | NFYB8 | Nuclear transcription factor Y subunit B-8 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAESQTGGGG | GGSHESGGDQ | SPRSLNVREQ | DRFLPIANIS | RIMKRGLPLN | GKIAKDAKET |
| 70 | 80 | 90 | 100 | 110 | 120 |
| MQECVSEFIS | FVTSEASDKC | QREKRKTING | DDLLWAMATL | GFEDYIDPLK | VYLMRYREME |
| 130 | 140 | 150 | 160 | 170 | |
| GDTKGSGKGG | ESSAKRDGQP | SQVSQFSQVP | QQGSFSQGPY | GNSQGSNMMV | QMPGTE |