Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q63965
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q63965-F1 | Predicted | AlphaFoldDB |
No variants for Q63965
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q63965 | |||||
No associated diseases with Q63965
No regional properties for Q63965
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q63965 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of mitochondrial inner membrane | The component of the mitochondrial inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
5 GO annotations of molecular function
| Name | Definition |
|---|---|
| D-serine transmembrane transporter activity | Enables the transfer of D-serine from one side of a membrane to the other. D-serine is the D-enantiomer of 2-amino-3-hydroxypropanoic acid. |
| L-alanine transmembrane transporter activity | Enables the transfer of L-alanine from one side of a membrane to the other. L-alanine is the L-enantiomer of 2-aminopropanoic acid. |
| L-serine transmembrane transporter activity | Enables the transfer of L-serine from one side of a membrane to the other. L-serine is the L-enantiomer of 2-amino-3-hydroxypropanoic acid. |
| serine transmembrane transporter activity | Enables the transfer of serine from one side of a membrane to the other. Serine is 2-amino-3-hydroxypropanoic acid. |
| transmembrane transporter activity | Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. |
8 GO annotations of biological process
| Name | Definition |
|---|---|
| D-serine transport | The directed movement of D-serine, the D-enantiomer of 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| erythrocyte differentiation | The process in which a myeloid precursor cell acquires specializes features of an erythrocyte. |
| iron ion transport | The directed movement of iron (Fe) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| L-alanine transport | The directed movement of L-alanine, the L-enantiomer of 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| L-serine transport | The directed movement of L-serine, the L-enantiomer of 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| mitochondrial transmembrane transport | The process in which a solute is transported from one side of a membrane to the other into, out of or within a mitochondrion. |
| one-carbon metabolic process | The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states. |
| serine import into mitochondrion | The process in which serine is transported from the cytosol into the mitochondrial matrix. |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q5E9M8 | SFXN1 | Sideroflexin-1 | Bos taurus (Bovine) | PR |
| Q9H9B4 | SFXN1 | Sideroflexin-1 | Homo sapiens (Human) | PR |
| Q99JR1 | Sfxn1 | Sideroflexin-1 | Mus musculus (Mouse) | PR |
| A5A761 | SFXN1 | Sideroflexin-1 | Sus scrofa (Pig) | PR |
| Q5FC79 | sfxn-5 | Sideroflexin-5 | Caenorhabditis elegans | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSGEVPPNIN | IKEPRWDQST | FIGRASHFFT | VTDPKNILLT | NEQLENARKV | VHDYRQGIVP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AGLTENELWR | AKYAYDSAFH | PDTGEKMTLI | GRMSAQVPMN | MTITGCMMTF | YRTTPAVLFW |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QWINQSFNAV | VNYTNRSGDA | PLTVNELGTA | YVSATTGAVA | TALGLNALTK | HVSPLIGRFV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PFAAVAAANC | INIPLMRQRE | LKVGIPVTDE | NGTRLGESTN | AAKQAITQVV | ISRILMAAPG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| MAIPPFIMNT | LEKKAFLKRF | PWMSAPIQVT | LVGFCLVFAT | PLCCALFPQK | SSMSVTSLED |
| 310 | 320 | ||||
| DLQASIQKSH | PELRRVYFNK | GL |