Q5FC79

PR
Gene name
sfxn-5
Protein name
Sideroflexin-5
Names
Species
Caenorhabditis elegans
KEGG Pathway
cel:CELE_C41C4.10
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

36-108 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5FC79

Entry ID Method Resolution Chain Position Source
AF-Q5FC79-F1 Predicted AlphaFoldDB

No variants for Q5FC79

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5FC79

No associated diseases with Q5FC79

2 regional properties for Q5FC79

Type Name Position InterPro Accession
domain GB1/RHD3-type guanine nucleotide-binding (G) domain 49 - 305 IPR030386
domain Sey1/RHD3-like, three-helix bundle domain 368 - 806 IPR046758

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of mitochondrial inner membrane The component of the mitochondrial inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
ion transmembrane transporter activity Enables the transfer of an ion from one side of a membrane to the other.
transmembrane transporter activity Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.

2 GO annotations of biological process

Name Definition
amino acid transport The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
mitochondrial transmembrane transport The process in which a solute is transported from one side of a membrane to the other into, out of or within a mitochondrion.

5 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q5E9M8 SFXN1 Sideroflexin-1 Bos taurus (Bovine) PR
Q9H9B4 SFXN1 Sideroflexin-1 Homo sapiens (Human) PR
Q99JR1 Sfxn1 Sideroflexin-1 Mus musculus (Mouse) PR
A5A761 SFXN1 Sideroflexin-1 Sus scrofa (Pig) PR
Q63965 Sfxn1 Sideroflexin-1 Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MALDETLFGY PIYPKFKLGE PRFPQDTFLG RYLHCLDVID PRTLFASNKK LEESLELLNS
70 80 90 100 110 120
FKAGTATNVP DKSLWEAQKL KSAILHPDTG EKVLPPFRMS GFVPFGWITV TGMLLPNPSW
130 140 150 160 170 180
PTLLFWQWMN QSHNACVNYA NRNATQPQPL SKYIGAYGAA VTAACSISGG LTYFIKKASS
190 200 210 220 230 240
LPPTTRIIIQ RFVPLPATSL ASSLNVICMR WNELETGIQV YEKDTGKVVG VSKVAAKQAV
250 260 270 280 290 300
TDTTMVRAFL PVPLLLMPPC IMPYLERFKW VTKTQVRHIF VNAIVCTLSF AVSLPVALAL
310 320 330
FPQESAISRE QLEPELQQKT KNSLLYYNKG L