Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q5ZKI6

Entry ID Method Resolution Chain Position Source
AF-Q5ZKI6-F1 Predicted AlphaFoldDB

No variants for Q5ZKI6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5ZKI6

No associated diseases with Q5ZKI6

No regional properties for Q5ZKI6

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q5ZKI6

Functions

Description
EC Number 2.4.2.42 Pentosyltransferases
Subcellular Localization
  • Membrane ; Single-pass type II membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase activity Catalyzes the reaction: UDP-alpha-D-xylose + -3-O-(beta-D-glucosyl)-L-serine <=> UDP + -3-O-(alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine.
UDP-xylosyltransferase activity Catalysis of the transfer of a xylosyl group from UDP-xylose to an acceptor molecule.

1 GO annotations of biological process

Name Definition
O-glycan processing The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form a core O-glycan structure.

8 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q5EA01 B4GAT1 Beta-1,4-glucuronyltransferase 1 Bos taurus (Bovine) PR
Q66PG4 LARGE2 Xylosyl- and glucuronyltransferase LARGE2s Gallus gallus (Chicken) PR
O43505 B4GAT1 Beta-1,4-glucuronyltransferase 1 Homo sapiens (Human) PR
A0PJZ3 GXYLT2 Glucoside xylosyltransferase 2 Homo sapiens (Human) PR
Q810K9 Gxylt2 Glucoside xylosyltransferase 2 Mus musculus (Mouse) PR
Q8BWP8 B4gat1 Beta-1,4-glucuronyltransferase 1 Mus musculus (Mouse) PR
Q21389 lge-1 Glycosyltransferase-like protein LARGE Caenorhabditis elegans PR
L7YAI7 b4gat1 Beta-1,4-glucuronyltransferase 1 Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MRRFARVALL FLGCGVCSLL YGVSQLALSL EQEAGGARQR QARESAAPGG GRQAGSADGG
70 80 90 100 110 120
EEGAGRCKNL SVSFWNSYWM LPSDVCGVNC FWEAAFRYTY METQPSETMH LAVVACGERL
130 140 150 160 170 180
EETITMLRSA IIFSIKPLHF HIFAEDQLHE SFKDILDDFP YEGKVNYTLY PITFPSEGAK
190 200 210 220 230 240
EWKKLFKPCA SQRLFLPLIL KDVDSLLYVD TDILFLRPVD DIWSFLRKFD STQIAAMAPE
250 260 270 280 290 300
HEEPRIGWYN RFARHPYYGV TGINSGVMLM NMTRIRRKYF KNDMTSVRLR WAEILMPLLK
310 320 330 340 350 360
KYKLNITWGD QDLLNIMFFH NPESLYVFPC QWNYRPDHCI YGSNCKEAEE EGIFILHGNR
370 380 390 400 410 420
GVYHDDKQPT FRAVYEAIKN YSFGDDLVRS LLQPLELELQ KTVHTYCGRV YEVFIKQLKK
430
SIKDLSVRRS KGS