Q5WA72

PR
Gene name
PDIL1-5 (PDIL3-1)
Protein name
Protein disulfide isomerase-like 1-5
Names
OsPDIL1-5, Protein disulfide isomerase-like 3-1, OsPDIL3-1
Species
Oryza sativa subsp japonica (Rice)
KEGG Pathway
osa:4340223
EC number
5.3.4.1: Transposing S-S bonds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-94 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5WA72

Entry ID Method Resolution Chain Position Source
AF-Q5WA72-F1 Predicted AlphaFoldDB

No variants for Q5WA72

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5WA72

No associated diseases with Q5WA72

2 regional properties for Q5WA72

Type Name Position InterPro Accession
domain Thioredoxin domain 51 - 196 IPR013766-1
domain Thioredoxin domain 387 - 516 IPR013766-2

Functions

Description
EC Number 5.3.4.1 Transposing S-S bonds
Subcellular Localization
  • Endoplasmic reticulum lumen
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
endoplasmic reticulum lumen The volume enclosed by the membranes of the endoplasmic reticulum.

1 GO annotations of molecular function

Name Definition
protein disulfide isomerase activity Catalysis of the rearrangement of both intrachain and interchain disulfide bonds in proteins.

2 GO annotations of biological process

Name Definition
protein folding The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
response to endoplasmic reticulum stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.

6 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q29RV1 PDIA4 Protein disulfide-isomerase A4 Bos taurus (Bovine) PR
Q8N807 PDILT Protein disulfide-isomerase-like protein of the testis Homo sapiens (Human) PR
Q13087 PDIA2 Protein disulfide-isomerase A2 Homo sapiens (Human) PR
Q17770 pdi-2 Protein disulfide-isomerase 2 Caenorhabditis elegans PR
A3KPF5 PDIL1-5 Protein disulfide isomerase-like 1-5 Arabidopsis thaliana (Mouse-ear cress) PR
Q66GQ3 PDIL1-6 Protein disulfide isomerase-like 1-6 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MRARRVVAAA AVLLLFAVVA VARLDLDDDG DDSEVLDELL AVDEEEERGE LGGGGEAAAA
70 80 90 100 110 120
EAVRRAQSMV LVLDNDNARR AVEENAEVLL LGYAPWCERS AQLMPRFAEA AAALRAMGSA
130 140 150 160 170 180
VAFAKLDGER YPKAASAVGV KGFPTVLLFV NGTEHQFTGL HTKDAIVTWV RKKTGAPASR
190 200 210 220 230 240
IQSKDSAEEF LKKDQTFAVG LFKNFEGAEY EEFVKAATSE NEVQFVETND RNVAKILFPG
250 260 270 280 290 300
IASEEQFLGL VKSEPEKFEK FNGAFEEKEI IQFVELNKFP LITVFTDLNS GKVYGSPIKL
310 320 330 340 350 360
QVFTFAEAYD FEDLESMIQE VARGFKTKIM LIYVDTAEEK LAKPFLTLYG LEPEKPTVTA
370 380 390 400 410 420
FDTSKGTKYL MEAEINAKNL QDFCLSLLEG TLPPYFRSEP VPEEKGPIEK VVGRTFDSSV
430 440 450 460 470 480
LESPQNVFLE VHAPWCVDCE AISKNVEKLA KHFNDLGQTN LKFARIDASV NEHPKLQINN
490 500 510 520 530
YPTLLLYPAQ DKSNPIKLSK KSNLKDMAKF VKEKLQIADV ETVAAGDIVK DEL