Q53M52
Gene name |
TUBA (Os11g0247300, LOC_Os11g14220) |
Protein name |
Tubulin alpha-2 chain |
Names |
|
Species |
Oryza sativa subsp japonica (Rice) |
KEGG Pathway |
osa:4350197 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q53M52
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q53M52-F1 | Predicted | AlphaFoldDB |
No variants for Q53M52
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q53M52 | |||||
No associated diseases with Q53M52
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| microtubule | Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| structural constituent of cytoskeleton | The action of a molecule that contributes to the structural integrity of a cytoskeletal structure. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| microtubule cytoskeleton organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. |
| mitotic cell cycle | Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent. |
15 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9ZRB7 | TUBA | Tubulin alpha chain | Triticum aestivum (Wheat) | PR |
| P09734 | TUB3 | Tubulin alpha-3 chain | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q6VAF9 | Tubulin alpha-4 chain | Gossypium hirsutum (Upland cotton) (Gossypium mexicanum) | PR | |
| Q6VAG0 | Tubulin alpha-2 chain | Gossypium hirsutum (Upland cotton) (Gossypium mexicanum) | PR | |
| P68366 | TUBA4A | Tubulin alpha-4A chain | Homo sapiens (Human) | PR |
| P22275 | TUBA3 | Tubulin alpha-3 chain | Zea mays (Maize) | PR |
| P33627 | TUBA6 | Tubulin alpha-6 chain | Zea mays (Maize) | PR |
| Q02245 | TUBA5 | Tubulin alpha-5 chain | Zea mays (Maize) | PR |
| P14640 | TUBA1 | Tubulin alpha-1 chain | Zea mays (Maize) | PR |
| P14641 | TUBA2 | Tubulin alpha-2 chain | Zea mays (Maize) | PR |
| P68368 | Tuba4a | Tubulin alpha-4A chain | Mus musculus (Mouse) | PR |
| P28752 | TUBA1 | Tubulin alpha-1 chain | Oryza sativa subsp japonica (Rice) | PR |
| B9DGT7 | TUBA2 | Tubulin alpha-2 chain | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q0WV25 | TUBA4 | Tubulin alpha-4 chain | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P29511 | TUBA6 | Tubulin alpha-6 chain | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRECISIHIG | QAGIQVGNAC | WELYCLEHGI | QPDGQMPGDK | TVGGGDDAFN | TFFSETGAGK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HVPRAVFVDL | EPTVIDEVRT | GDYRQLFHPE | QLISGKEDAA | NNFARGHYTI | GKEIVDLCLD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RIRKLADNCT | GLQGFLVFNA | VGGGTGSGLG | SLLLERLSVD | YGKKSKLGFT | VYPSPQVSTS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VVEPYNSVLS | THSLLEHTDV | AVLLDNEAIY | DICRRSLDIE | RPTYTNLNRL | VSQVISSLTA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SLRFDGALNV | DVNEFQTNLV | PYPRIHFMLS | SYAPVISAEK | AYHEQLSVAE | ITNSAFEPSS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| MMAKCDPRHG | KYMACCLMYR | GDVVPKDVNA | AVATIKTKRT | IQFVDWCPTG | FKCGINYQPP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SVVPGGDLAK | VQRAVCMISN | STSVVEVFSR | IDIKFDLMYS | KRAFVHWYVG | EGMEEGEFSE |
| 430 | 440 | 450 | |||
| AREDLAALEK | DYEEVGSEFD | DGDEGDEGDE | Y |