Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q43206

Entry ID Method Resolution Chain Position Source
AF-Q43206-F1 Predicted AlphaFoldDB

No variants for Q43206

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q43206

No associated diseases with Q43206

21 regional properties for Q43206

Type Name Position InterPro Accession
domain Immunoglobulin subtype 2 36 - 120 IPR003598-1
domain Immunoglobulin subtype 2 152 - 215 IPR003598-2
domain Immunoglobulin subtype 2 241 - 310 IPR003598-3
domain Immunoglobulin subtype 2 337 - 404 IPR003598-4
domain Immunoglobulin subtype 2 433 - 495 IPR003598-5
domain Immunoglobulin subtype 30 - 134 IPR003599-1
domain Immunoglobulin subtype 146 - 226 IPR003599-2
domain Immunoglobulin subtype 235 - 322 IPR003599-3
domain Immunoglobulin subtype 331 - 417 IPR003599-4
domain Immunoglobulin subtype 426 - 506 IPR003599-5
domain Fibronectin type III 232 - 302 IPR003961-1
domain Fibronectin type III 510 - 604 IPR003961-2
domain Fibronectin type III 614 - 708 IPR003961-3
domain Immunoglobulin-like domain 38 - 115 IPR007110-1
domain Immunoglobulin-like domain 139 - 226 IPR007110-2
domain Immunoglobulin-like domain 228 - 320 IPR007110-3
domain Immunoglobulin-like domain 324 - 415 IPR007110-4
domain Immunoglobulin-like domain 420 - 504 IPR007110-5
domain Immunoglobulin V-set domain 40 - 115 IPR013106-1
domain Immunoglobulin V-set domain 156 - 210 IPR013106-2
domain Immunoglobulin V-set domain 245 - 305 IPR013106-3

Functions

Description
EC Number 1.11.1.6 Peroxidases
Subcellular Localization
  • Peroxisome
  • Glyoxysome
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
glyoxysome A specialized form of peroxisome that contains the enzymes of the glyoxylate pathway. The glyoxysome is found in some plant cells, notably the cells of germinating seeds.
peroxisome A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
catalase activity Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
metal ion binding Binding to a metal ion.

4 GO annotations of biological process

Name Definition
hydrogen peroxide catabolic process The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).
response to abiotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus.
response to hormone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.
response to hydrogen peroxide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.

10 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P17336 Cat Catalase Drosophila melanogaster (Fruit fly) PR
P18122 CAT1 Catalase isozyme 1 Zea mays (Maize) PR
P24270 Cat Catalase Mus musculus (Mouse) PR
P04762 Cat Catalase Rattus norvegicus (Rat) PR
Q0E4K1 CATA Catalase isozyme A Oryza sativa subsp japonica (Rice) PR
Q0D9C4 CATB Catalase isozyme B Oryza sativa subsp japonica (Rice) PR
Q27487 ctl-2 Peroxisomal catalase 1 Caenorhabditis elegans PR
O61235 ctl-1 Catalase-2 Caenorhabditis elegans PR
P25819 CAT2 Catalase-2 Arabidopsis thaliana (Mouse-ear cress) PR
Q42547 CAT3 Catalase-3 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MDPYKYRPSS SFNAPMWSTN SGAPVWNNDN SLTVGSRGPI LLEDYHLVEK IADFDRERIP
70 80 90 100 110 120
ERVVHARGAT AKGFFEVTHD VSHLTCADFL RAPGVQTPVI VRFSTVIHER GSPETLRDPR
130 140 150 160 170 180
GFAIKFYTRE GNWDLVGNNF PVFFIRDGMK FPDMVHALKP NPKTHIQENW RILDFFSHHP
190 200 210 220 230 240
ESLHMFTFLF DDIGVPADYR HMDGSGVNTY TLVNRAGKAH YVKFHWKPTC GVKSLLEEEA
250 260 270 280 290 300
VTVGGTNHSH ATKDLTDSIA AGNYPEWTFY IQTIDPDYEE RFDFDPLDVT KTWPEDVVPL
310 320 330 340 350 360
QPVGRLVLNR NIDNFFSENE QLAFCPGIIV PGVYYSDDKL LQTRIFSYSD TQRHRLGPNY
370 380 390 400 410 420
LLLPANAPKC SHHNNHYDGL MNFMHRDEEV DYFPSRFDPA KHAPRYPIPS RTLNGRREKM
430 440 450 460 470 480
VIEKENNFKQ PGERYRSMDP ARQERFINRW IDALSDPRLT HEIKAIWLSY WSQADKSLGQ
490
KLASRLSSKP SM