Q42547

PR
Gene name
CAT3 (At1g20620, F2D10.40, F5M15.5)
Protein name
Catalase-3
Names
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT1G20620
EC number
1.11.1.6: Peroxidases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-54 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q42547

Entry ID Method Resolution Chain Position Source
AF-Q42547-F1 Predicted AlphaFoldDB

10 variants for Q42547

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH11638950 79 H>Y No 1000Genomes
tmp_1_7144633_A_G 96 Q>R No 1000Genomes
tmp_1_7145015_G_A 193 V>I No 1000Genomes
tmp_1_7145314_C_G 292 I>M No 1000Genomes
ENSVATH04610329 378 E>D No 1000Genomes
tmp_1_7145921_C_G 433 D>E No 1000Genomes
ENSVATH11639196 454 L>I No 1000Genomes
ENSVATH00034232 466 I>V No 1000Genomes
ENSVATH13933512 479 G>R No 1000Genomes
tmp_1_7146188_A_C 492 I>L No 1000Genomes

No associated diseases with Q42547

3 regional properties for Q42547

Type Name Position InterPro Accession
binding_site Catalase haem-binding site 344 - 352 IPR002226
domain Catalase immune-responsive domain 422 - 486 IPR010582
domain Catalase core domain 18 - 401 IPR011614

Functions

Description
EC Number 1.11.1.6 Peroxidases
Subcellular Localization
  • Peroxisome
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

14 GO annotations of cellular component

Name Definition
apoplast The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it.
chloroplast A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
chloroplast envelope The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
chloroplast stroma The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
cytosolic ribosome A ribosome located in the cytosol.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
peroxisome A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
plant-type cell wall A more or less rigid stucture lying outside the cell membrane of a cell and composed of cellulose and pectin and other organic and inorganic substances.
plant-type vacuole A closed structure that is completely surrounded by a unit membrane, contains liquid, and retains the same shape regardless of cell cycle phase. An example of this structure is found in Arabidopsis thaliana.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
plasmodesma A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.

5 GO annotations of molecular function

Name Definition
catalase activity Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
cobalt ion binding Binding to a cobalt ion (Co).
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
mRNA binding Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
peptidyl-cysteine S-nitrosylase activity Catalysis of the transfer of a nitric oxide (NO) group to a sulphur atom within a cysteine residue of a protein.

8 GO annotations of biological process

Name Definition
cellular response to nitrogen starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nitrogen.
cellular response to phosphate starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of phosphate.
cellular response to sulfate starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfate.
hydrogen peroxide catabolic process The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).
peptidyl-cysteine S-trans-nitrosylation Transfer of a nitric oxide (NO) group from one cysteine residue to another.
response to cold Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
response to hydrogen peroxide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
response to light stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.

10 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q43206 CAT1 Catalase-1 Triticum aestivum (Wheat) PR
P17336 Cat Catalase Drosophila melanogaster (Fruit fly) PR
P18122 CAT1 Catalase isozyme 1 Zea mays (Maize) PR
P24270 Cat Catalase Mus musculus (Mouse) PR
P04762 Cat Catalase Rattus norvegicus (Rat) PR
Q0E4K1 CATA Catalase isozyme A Oryza sativa subsp japonica (Rice) PR
Q0D9C4 CATB Catalase isozyme B Oryza sativa subsp japonica (Rice) PR
Q27487 ctl-2 Peroxisomal catalase 1 Caenorhabditis elegans PR
O61235 ctl-1 Catalase-2 Caenorhabditis elegans PR
P25819 CAT2 Catalase-2 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MDPYKYRPSS AYNAPFYTTN GGAPVSNNIS SLTIGERGPV LLEDYHLIEK VANFTRERIP
70 80 90 100 110 120
ERVVHARGIS AKGFFEVTHD ISNLTCADFL RAPGVQTPVI VRFSTVVHER ASPETMRDIR
130 140 150 160 170 180
GFAVKFYTRE GNFDLVGNNT PVFFIRDGIQ FPDVVHALKP NPKTNIQEYW RILDYMSHLP
190 200 210 220 230 240
ESLLTWCWMF DDVGIPQDYR HMEGFGVHTY TLIAKSGKVL FVKFHWKPTC GIKNLTDEEA
250 260 270 280 290 300
KVVGGANHSH ATKDLHDAIA SGNYPEWKLF IQTMDPADED KFDFDPLDVT KIWPEDILPL
310 320 330 340 350 360
QPVGRLVLNR TIDNFFNETE QLAFNPGLVV PGIYYSDDKL LQCRIFAYGD TQRHRLGPNY
370 380 390 400 410 420
LQLPVNAPKC AHHNNHHEGF MNFMHRDEEI NYYPSKFDPV RCAEKVPTPT NSYTGIRTKC
430 440 450 460 470 480
VIKKENNFKQ AGDRYRSWAP DRQDRFVKRW VEILSEPRLT HEIRGIWISY WSQADRSLGQ
490
KLASRLNVRP SI