Q336V5

PR
Gene name
ACR2.1 (CDC25.1, STR20)
Protein name
Arsenate reductase 2.1
Names
OsACR2.1, Dual specificity phosphatase CDC25.1, Sulfurtransferase 20, OsStr20
Species
Oryza sativa subsp japonica (Rice)
KEGG Pathway
osa:4349283
EC number
1.20.4.1: With disulfide as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-107 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q336V5

Entry ID Method Resolution Chain Position Source
AF-Q336V5-F1 Predicted AlphaFoldDB

No variants for Q336V5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q336V5

No associated diseases with Q336V5

1 regional properties for Q336V5

Type Name Position InterPro Accession
domain Rhodanese-like domain 32 - 143 IPR001763

Functions

Description
EC Number 1.20.4.1 With disulfide as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

3 GO annotations of molecular function

Name Definition
arsenate reductase (glutaredoxin) activity Catalysis of the reaction: arsenate + reduced glutaredoxin = arsenite + oxidized glutaredoxin. Glutaredoxin functions as the electron donor for arsenate reduction. The electron flow therefore is ( NADPH -> glutathione reductase (EC:1.6.4.2) -> ) glutathione -> glutaredoxin -> arsenate reductase, i.e. glutathione is reduced by glutathione reductase and glutaredoxin is reduced by glutathione.
phosphatase activity Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
protein tyrosine phosphatase activity Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P20483 stg M-phase inducer phosphatase Drosophila melanogaster (Fruit fly) PR
P30305 CDC25B M-phase inducer phosphatase 2 Homo sapiens (Human) PR
P30304 CDC25A M-phase inducer phosphatase 1 Homo sapiens (Human) PR
P30306 Cdc25b M-phase inducer phosphatase 2 Mus musculus (Mouse) PR
10 20 30 40 50 60
MCRFLISTPF SRRRGERKAE AGRMARSVSY VSAAKLLAMA RSNPRVAIID VRDEERSYQA
70 80 90 100 110 120
HIGGSHHFSS RSFAARLPEL ARATGDKDTV VFHCALSKVR GPSCAKMFSD YLSETKEESG
130 140 150
TKNIMVLERG FNGWELSGQP VCRCTDAPCK GTCSPEEPEL