Q27371
Gene name |
mup-2 (T22E5.5) |
Protein name |
Troponin T |
Names |
|
Species |
Caenorhabditis elegans |
KEGG Pathway |
cel:CELE_T22E5.5 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q27371
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q27371-F1 | Predicted | AlphaFoldDB |
No variants for Q27371
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q27371 | |||||
No associated diseases with Q27371
No regional properties for Q27371
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q27371 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| troponin complex | A complex of accessory proteins (typically troponin T, troponin I and troponin C) found associated with actin in muscle thin filaments; involved in calcium regulation of muscle contraction. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| tropomyosin binding | Binding to tropomyosin, a protein associated with actin filaments both in cytoplasm and, in association with troponin, in the thin filament of striated muscle. |
7 GO annotations of biological process
| Name | Definition |
|---|---|
| axonal fasciculation | The collection of axons into a bundle of rods, known as a fascicle. |
| embryonic morphogenesis | The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants. |
| larval somatic muscle development | The process whose specific outcome is the progression of the larval somatic muscle over time, from its formation to the mature structure. |
| muscle contraction | A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. |
| ovulation | The release of a mature ovum/oocyte from an ovary. |
| regulation of muscle contraction | Any process that modulates the frequency, rate or extent of muscle contraction. |
| sarcomere organization | The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. |
7 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P13789 | TNNT2 | Troponin T, cardiac muscle | Bos taurus (Bovine) | PR |
| P02642 | TNNT2 | Troponin T, cardiac muscle isoforms | Gallus gallus (Chicken) | PR |
| P45378 | TNNT3 | Troponin T, fast skeletal muscle | Homo sapiens (Human) | PR |
| P50752 | Tnnt2 | Troponin T, cardiac muscle | Mus musculus (Mouse) | PR |
| Q9QZ47 | Tnnt3 | Troponin T, fast skeletal muscle | Mus musculus (Mouse) | PR |
| P50753 | Tnnt2 | Troponin T, cardiac muscle | Rattus norvegicus (Rat) | PR |
| P09739 | Tnnt3 | Troponin T, fast skeletal muscle | Rattus norvegicus (Rat) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSDEEEVYSD | EEVEEEEVEE | TEEAPAEAEE | PEETTEEVVA | PPEVKERRAP | VQEEKPPAEM |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TEAEIAMLAA | KKRHEEEEAA | KLLDYEQRRV | LEKEQIEQEL | RELKEKQEKR | RAEREEDERQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FAERRRQDDE | RRRKEEDERK | AKADAEKIRK | NEEKVRRQQM | MAGAFNGRVE | AGAGRNFTVA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SKGDQAAQFG | NLAQAKGGKD | VMSKEQMEDA | KRNFLAAVCR | VQDVSGLLPN | DLKERIRGLH |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ARIVKLEAEK | YDLEKRRERQ | DYDMKELHER | QRQAARNKAL | KKGLDPEEAA | SSVHPPKITT |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ASKFDRQTDR | RSYGDRRYLF | ENPEEEKQAS | LVRGTGRPPA | EWGRKQNEEL | EQIRKNLEPP |
| 370 | 380 | 390 | 400 | ||
| KYVEQVKVEG | ARAPVEPVPL | FVPTDDFEPQ | QVTEDPNVGE | EVVVE |