Q07915
Gene name |
RLP24 (YLR009W) |
Protein name |
Ribosome biogenesis protein RLP24 |
Names |
Ribosomal protein L24-like |
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YLR009W |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
43 structures for Q07915
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 3JCT | EM | 308 A | u | 1-199 | PDB |
| 4V7F | EM | 870 A | p | 1-199 | PDB |
| 5JCS | EM | 950 A | t | 1-199 | PDB |
| 6C0F | EM | 370 A | u | 1-199 | PDB |
| 6ELZ | EM | 330 A | u | 1-199 | PDB |
| 6EM1 | EM | 360 A | u | 1-199 | PDB |
| 6EM4 | EM | 410 A | u | 1-199 | PDB |
| 6EM5 | EM | 430 A | u | 1-199 | PDB |
| 6FT6 | EM | 390 A | u | 1-199 | PDB |
| 6M62 | EM | 320 A | u | 1-199 | PDB |
| 6N8J | EM | 350 A | u | 1-199 | PDB |
| 6N8K | EM | 360 A | u | 1-199 | PDB |
| 6N8L | EM | 360 A | u | 1-199 | PDB |
| 6YLG | EM | 300 A | u | 1-199 | PDB |
| 6YLH | EM | 310 A | u | 1-199 | PDB |
| 6YLX | EM | 390 A | u | 1-199 | PDB |
| 6YLY | EM | 380 A | u | 1-199 | PDB |
| 7BT6 | EM | 312 A | u | 1-199 | PDB |
| 7BTB | EM | 322 A | u | 1-199 | PDB |
| 7NAC | EM | 304 A | u | 1-199 | PDB |
| 7NAD | EM | 304 A | u | 1-199 | PDB |
| 7NAF | EM | 313 A | u | 1-65 | PDB |
| 7OF1 | EM | 310 A | u | 1-199 | PDB |
| 7OH3 | EM | 340 A | u | 1-199 | PDB |
| 7OHQ | EM | 310 A | u | 1-199 | PDB |
| 7OHR | EM | 472 A | u | 1-199 | PDB |
| 7OHS | EM | 438 A | u | 1-199 | PDB |
| 7OHT | EM | 470 A | u | 1-199 | PDB |
| 7OHU | EM | 370 A | u | 1-199 | PDB |
| 7OHV | EM | 390 A | u | 1-199 | PDB |
| 7OHX | EM | 330 A | u | 1-199 | PDB |
| 7OHY | EM | 390 A | u | 1-199 | PDB |
| 7R72 | EM | 307 A | u | 1-199 | PDB |
| 7R7A | EM | 304 A | u | 1-199 | PDB |
| 7U0H | EM | 276 A | u | 1-199 | PDB |
| 7UG6 | EM | 290 A | u | 1-199 | PDB |
| 7UOO | EM | 234 A | u | 1-199 | PDB |
| 7UQB | EM | 243 A | u | 1-199 | PDB |
| 7UQZ | EM | 244 A | u | 1-199 | PDB |
| 7V08 | EM | 236 A | u | 1-199 | PDB |
| 7Z34 | EM | 380 A | u | 1-199 | PDB |
| 8HFR | EM | 264 A | tB | 1-199 | PDB |
| AF-Q07915-F1 | Predicted | AlphaFoldDB |
2 variants for Q07915
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s12-166875 | 114 | G>S | No | SGRP | |
| s12-166908 | 125 | K>Q | No | SGRP |
No associated diseases with Q07915
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
| preribosome, large subunit precursor | A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATPase activator activity | Binds to and increases the activity of an ATP hydrolysis activity. |
| ATPase binding | Binding to an ATPase, any enzyme that catalyzes the hydrolysis of ATP. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| assembly of large subunit precursor of preribosome | The aggregation, arrangement and bonding together of a set of components to form the large subunit precursor of the preribosome. |
| positive regulation of ATP-dependent activity | Any process that activates or increases the rate of an ATP-dependent activity. |
| ribosomal large subunit biogenesis | A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis. |
7 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P04449 | RPL24A | 60S ribosomal protein L24-A | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q3SZ12 | RSL24D1 | Probable ribosome biogenesis protein RLP24 | Bos taurus (Bovine) | PR |
| Q9UHA3 | RSL24D1 | Probable ribosome biogenesis protein RLP24 | Homo sapiens (Human) | PR |
| Q99L28 | Rsl24d1 | Probable ribosome biogenesis protein RLP24 | Mus musculus (Mouse) | PR |
| Q6P6G7 | Rsl24d1 | Probable ribosome biogenesis protein RLP24 | Rattus norvegicus (Rat) | PR |
| Q17606 | rpl-24.2 | Probable ribosome biogenesis protein RLP24 | Caenorhabditis elegans | PR |
| Q7ZTZ2 | rsl24d1 | Probable ribosome biogenesis protein RLP24 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRIYQCHFCS | SPCYPGHGIM | FVRNDAKEFR | FCRSKCHKAF | KQRRNPRKLK | WTKAFRKAAG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KELAVDSTLT | FAQRRNVPVR | YNRELVATTL | KAMARIEEIR | QKRERAFYKN | RMRGNKEKDF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LRDKKLVESN | PELLRIREVE | IARKLAKEQE | RAESVSEQEE | SEEEEEDMEI | DSDEEEEEQL |
| 190 | |||||
| EKQKILLKNR | RRNTKKIAF |