Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q7ZTZ2

Entry ID Method Resolution Chain Position Source
AF-Q7ZTZ2-F1 Predicted AlphaFoldDB

No variants for Q7ZTZ2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7ZTZ2

No associated diseases with Q7ZTZ2

2 regional properties for Q7ZTZ2

Type Name Position InterPro Accession
conserved_site Ribosomal RNA adenine methylase transferase, conserved site 52 - 79 IPR020596
domain Ribosomal RNA adenine methylase transferase, N-terminal 36 - 213 IPR020598

Functions

Description
EC Number
Subcellular Localization
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
ribosomal large subunit biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis.

6 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q07915 RLP24 Ribosome biogenesis protein RLP24 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
Q3SZ12 RSL24D1 Probable ribosome biogenesis protein RLP24 Bos taurus (Bovine) PR
Q9UHA3 RSL24D1 Probable ribosome biogenesis protein RLP24 Homo sapiens (Human) PR
Q99L28 Rsl24d1 Probable ribosome biogenesis protein RLP24 Mus musculus (Mouse) PR
Q6P6G7 Rsl24d1 Probable ribosome biogenesis protein RLP24 Rattus norvegicus (Rat) PR
Q17606 rpl-24.2 Probable ribosome biogenesis protein RLP24 Caenorhabditis elegans PR
10 20 30 40 50 60
MRIEKCYFCS APVYPGHGMM FVRNDCKVFR FCRSKCHKNF KKKRNPRKTR WTKAFRKSAG
70 80 90 100 110 120
KELTVDNSLE FEKRRNTPVK YNRELWSKTV EAMRKVESIK HKRQARFIMN RLKKGKELEK
130 140 150 160
AADISEVKKN IHLIKAPHAG QAKQLEDKMV QKLAEDVEMD E