P04449

PR
Gene name
RPL24A
Protein name
60S ribosomal protein L24-A
Names
L30, Large ribosomal subunit protein eL24-A, RP29, YL21
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YGL031C
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

90-155 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

128 structures for P04449

Entry ID Method Resolution Chain Position Source
2X7N EM 1180 A D 1-56 PDB
3J6X EM 610 A 64 1-155 PDB
3J6Y EM 610 A 64 1-155 PDB
3J77 EM 620 A 74 1-155 PDB
3J78 EM 630 A 74 1-155 PDB
4U3M X-ray 300 A N4/n4 1-155 PDB
4U3N X-ray 320 A N4/n4 1-155 PDB
4U3U X-ray 290 A N4/n4 1-155 PDB
4U4N X-ray 310 A N4/n4 1-155 PDB
4U4O X-ray 360 A N4/n4 1-155 PDB
4U4Q X-ray 300 A N4/n4 1-155 PDB
4U4R X-ray 280 A N4/n4 1-155 PDB
4U4U X-ray 300 A N4/n4 1-155 PDB
4U4Y X-ray 320 A N4/n4 1-155 PDB
4U4Z X-ray 310 A N4/n4 1-155 PDB
4U50 X-ray 320 A N4/n4 1-155 PDB
4U51 X-ray 320 A N4/n4 1-155 PDB
4U52 X-ray 300 A N4/n4 1-155 PDB
4U53 X-ray 330 A N4/n4 1-155 PDB
4U55 X-ray 320 A N4/n4 1-155 PDB
4U56 X-ray 345 A N4/n4 1-155 PDB
4U6F X-ray 310 A N4/n4 1-155 PDB
4V4B EM 1170 A BS 1-56 PDB
4V6I EM 880 A BZ 1-155 PDB
4V7R X-ray 400 A BV/DV 1-155 PDB
4V88 X-ray 300 A BW/DW 1-155 PDB
4V8T EM 810 A W 1-155 PDB
4V8Y EM 430 A BW 1-155 PDB
4V8Z EM 660 A BW 1-155 PDB
4V91 EM 370 A W 1-155 PDB
5APN EM 391 A W 1-155 PDB
5APO EM 341 A W 1-155 PDB
5DAT X-ray 315 A N4/n4 1-155 PDB
5DC3 X-ray 325 A N4/n4 1-155 PDB
5DGE X-ray 345 A N4/n4 1-155 PDB
5DGF X-ray 330 A N4/n4 1-155 PDB
5DGV X-ray 310 A N4/n4 1-155 PDB
5FCI X-ray 340 A N4/n4 1-155 PDB
5FCJ X-ray 310 A N4/n4 1-155 PDB
5GAK EM 388 A Y 1-155 PDB
5H4P EM 307 A W 1-155 PDB
5I4L X-ray 310 A PDB
5JUO EM 400 A BA 1-155 PDB
5JUP EM 350 A BA 1-155 PDB
5JUS EM 420 A BA 1-155 PDB
5JUT EM 400 A BA 1-155 PDB
5JUU EM 400 A BA 1-155 PDB
5LYB X-ray 325 A PDB
5M1J EM 330 A W5 1-98 PDB
5MC6 EM 380 A AE 1-155 PDB
5MEI X-ray 350 A 7/CY 1-98 PDB
5NDG X-ray 370 A N4/n4 1-155 PDB
5NDV X-ray 330 A N4/n4 1-155 PDB
5NDW X-ray 370 A N4/n4 1-155 PDB
5OBM X-ray 340 A PDB
5ON6 X-ray 310 A 7/CY 1-98 PDB
5T62 EM 330 A j 1-155 PDB
5T6R EM 450 A j 1-155 PDB
5TBW X-ray 300 A 7/CY 1-98 PDB
5TGA X-ray 330 A N4/n4 1-135 PDB
5TGM X-ray 350 A PDB
6GQ1 EM 440 A W 1-63 PDB
6GQB EM 390 A W 1-64 PDB
6GQV EM 400 A W 1-62 PDB
6HD7 EM 340 A Y 1-155 PDB
6HHQ X-ray 310 A 7/CY 1-155 PDB
6I7O EM 530 A AE/XE 1-135 PDB
6N8M EM 350 A j 1-155 PDB
6N8N EM 380 A j 1-155 PDB
6N8O EM 350 A j 1-155 PDB
6OIG EM 380 A W 1-135 PDB
6Q8Y EM 310 A AE 1-67 PDB
6QIK EM 310 A v 1-155 PDB
6QT0 EM 340 A v 1-155 PDB
6QTZ EM 350 A v 1-155 PDB
6R84 EM 360 A Y 1-62 PDB
6R86 EM 340 A Y 1-62 PDB
6R87 EM 340 A Y 1-62 PDB
6RI5 EM 330 A v 1-155 PDB
6RZZ EM 320 A v 1-155 PDB
6S05 EM 390 A v 1-155 PDB
6S47 EM 328 A AY 1-155 PDB
6SNT EM 280 A at 1-155 PDB
6SV4 EM 330 A AE/XE/zE 1-135 PDB
6T4Q EM 260 A LW 1-126 PDB
6T7T EM 310 A LW 1-155 PDB
6T83 EM 400 A H/Wy 1-155 PDB
6TB3 EM 280 A AE 1-126 PDB
6TNU EM 310 A AE 1-126 PDB
6WOO EM 290 A W 2-63 PDB
6Z6J EM 340 A LW 1-155 PDB
6Z6K EM 340 A LW 1-155 PDB
7AZY EM 288 A f 1-155 PDB
7B7D EM 330 A LS 1-126 PDB
7MPI EM 305 A AW 1-63 PDB
7MPJ EM 270 A AW 1-63 PDB
7N8B EM 305 A AW 1-63 PDB
7NRC EM 390 A LY 1-65 PDB
7NRD EM 436 A LY 1-61 PDB
7ZPQ EM 347 A BV 1-126 PDB
7ZRS EM 480 A BV 1-126 PDB
7ZS5 EM 320 A BX 1-69 PDB
7ZUW EM 430 A BV 1-126 PDB
7ZUX EM 250 A EV 1-126 PDB
7ZW0 EM 240 A LZ 1-155 PDB
8AAF EM 250 A J 1-155 PDB
8AGT EM 260 A J 1-155 PDB
8AGU EM 270 A J 1-155 PDB
8AGV EM 260 A J 1-155 PDB
8AGW EM 260 A J 1-155 PDB
8AGX EM 240 A J 1-155 PDB
8AGZ EM 260 A J 1-155 PDB
8BIP EM 310 A LW 1-126 PDB
8BJQ EM 380 A LW 1-126 PDB
8BQD EM 390 A AE 1-126 PDB
8BQX EM 380 A AE 1-126 PDB
8CCS EM 197 A I 1-155 PDB
8CDL EM 272 A I 1-155 PDB
8CDR EM 204 A I 1-155 PDB
8CEH EM 205 A I 1-155 PDB
8CF5 EM 271 A I 1-155 PDB
8CG8 EM 257 A I 1-155 PDB
8CGN EM 228 A I 1-155 PDB
8CIV EM 247 A I 1-155 PDB
8CKU EM 311 A I 1-155 PDB
8CMJ EM 379 A I 1-155 PDB
8Y0U EM 359 A LW 1-155 PDB
AF-P04449-F1 Predicted AlphaFoldDB

1 variants for P04449

Variant ID(s) Position Change Description Diseaes Association Provenance
s07-437620 107 E>G No SGRP

No associated diseases with P04449

1 regional properties for P04449

Type Name Position InterPro Accession
conserved_site Ribosomal protein L24e, conserved site 8 - 25 IPR023442

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
cytosolic large ribosomal subunit The large subunit of a ribosome located in the cytosol.

3 GO annotations of molecular function

Name Definition
mRNA binding Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
RNA binding Binding to an RNA molecule or a portion thereof.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

1 GO annotations of biological process

Name Definition
cytoplasmic translation The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q07915 RLP24 Ribosome biogenesis protein RLP24 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
Q42347 RPL24A 60S ribosomal protein L24-1 Arabidopsis thaliana (Mouse-ear cress) PR
P38666 RPL24B 60S ribosomal protein L24-2 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MKVEIDSFSG AKIYPGRGTL FVRGDSKIFR FQNSKSASLF KQRKNPRRIA WTVLFRKHHK
70 80 90 100 110 120
KGITEEVAKK RSRKTVKAQR PITGASLDLI KERRSLKPEV RKANREEKLK ANKEKKKAEK
130 140 150
AARKAEKAKS AGTQSSKFSK QQAKGAFQKV AATSR