Q42347

PR
Gene name
RPL24A (At2g36620, F13K3.2, F1O11.25)
Protein name
60S ribosomal protein L24-1
Names
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT2G36620
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

34-164 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q42347

Entry ID Method Resolution Chain Position Source
AF-Q42347-F1 Predicted AlphaFoldDB

9 variants for Q42347

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_2_15351315_G_T 7 L>I No 1000Genomes
tmp_2_15351040_T_C 62 K>R No 1000Genomes
tmp_2_15350932_C_T 69 A>T No 1000Genomes
ENSVATH05666553 87 G>S No 1000Genomes
ENSVATH13551214 109 E>D No 1000Genomes
tmp_2_15350812_C_G 109 E>Q No 1000Genomes
tmp_2_15350675_T_C 123 K>R No 1000Genomes
tmp_2_15350661_C_T 128 A>T No 1000Genomes
tmp_2_15350606_A_G 146 I>T No 1000Genomes

No associated diseases with Q42347

2 regional properties for Q42347

Type Name Position InterPro Accession
domain TRASH domain 8 - 46 IPR011017
conserved_site Ribosomal protein L24e, conserved site 10 - 27 IPR023442

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytosolic large ribosomal subunit The large subunit of a ribosome located in the cytosol.
endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).

2 GO annotations of molecular function

Name Definition
mRNA binding Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

1 GO annotations of biological process

Name Definition
cytoplasmic translation The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P04449 RPL24A 60S ribosomal protein L24-A Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
P38666 RPL24B 60S ribosomal protein L24-2 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MVLKTELCRF SGQKIYPGRG IRFIRSDSQV FLFLNSKCKR YFHNKLKPSK LCWTAMYRKQ
70 80 90 100 110 120
HKKDAAQEAV KRRRRATKKP YSRSIVGATL EVIQKKRAEK PEVRDAAREA ALREIKERIK
130 140 150 160
KTKDEKKAKK VEYASKQQKS QVKGNIPKSA APKAAKMGGG GGRR