P49405
Gene name |
rpl-5 (F54C9.5) |
Protein name |
60S ribosomal protein L5 |
Names |
|
Species |
Caenorhabditis elegans |
KEGG Pathway |
cel:CELE_F54C9.5 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P49405
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P49405-F1 | Predicted | AlphaFoldDB |
No variants for P49405
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P49405 | |||||
No associated diseases with P49405
1 regional properties for P49405
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Ribosomal protein L5 eukaryotic, C-terminal | 238 - 287 | IPR025607 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosolic large ribosomal subunit | The large subunit of a ribosome located in the cytosol. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| 5S rRNA binding | Binding to a 5S ribosomal RNA, the smallest RNA constituent of a ribosome. |
| structural constituent of ribosome | The action of a molecule that contributes to the structural integrity of the ribosome. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| ribosomal large subunit assembly | The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit. |
| translation | The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. |
6 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q58DW5 | RPL5 | 60S ribosomal protein L5 | Bos taurus (Bovine) | PR |
| P22451 | RPL5 | 60S ribosomal protein L5 | Gallus gallus (Chicken) | PR |
| P46777 | RPL5 | 60S ribosomal protein L5 | Homo sapiens (Human) | PR |
| P47962 | Rpl5 | 60S ribosomal protein L5 | Mus musculus (Mouse) | PR |
| P09895 | Rpl5 | 60S ribosomal protein L5 | Rattus norvegicus (Rat) | PR |
| O76190 | RpL5 | 60S ribosomal protein L5 | Bombyx mori (Silk moth) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGLVKVIKNK | AYFKRYQVKL | RRRREGKTDY | YARKRLTVQD | KNKYNTPKYR | LIVRITNKDV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VAQLAYSKIE | GDVVVASAYS | HELPRYGLKV | GLTNYAAAYA | TGLLLARRHL | KTIGLDSTYK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GHEELTGEDY | NVEEEGDRAP | FKAVLDIGLA | RTTTGSKIFA | VMKGVADGGI | NVPHSESRFF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GFDQESKEYN | AEAHRDRILG | KHVADYMTYL | KEEDEDRYKR | QFSKFLAAGL | NADNLVATYQ |
| 250 | 260 | 270 | 280 | 290 | |
| KVHSAIRADA | SPAAKKAAKP | SKRHTAKRLT | YDERKQRVAD | KKALLLQLKE | QQE |