O76190
Gene name |
RpL5 |
Protein name |
60S ribosomal protein L5 |
Names |
|
Species |
Bombyx mori (Silk moth) |
KEGG Pathway |
bmor:692557 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O76190
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O76190-F1 | Predicted | AlphaFoldDB |
No variants for O76190
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O76190 | |||||
No associated diseases with O76190
1 regional properties for O76190
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Ribosomal protein L5 eukaryotic, C-terminal | 236 - 290 | IPR025607 |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| ribonucleoprotein complex | A macromolecular complex that contains both RNA and protein molecules. |
| ribosome | An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| 5S rRNA binding | Binding to a 5S ribosomal RNA, the smallest RNA constituent of a ribosome. |
| structural constituent of ribosome | The action of a molecule that contributes to the structural integrity of the ribosome. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| translation | The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. |
6 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q58DW5 | RPL5 | 60S ribosomal protein L5 | Bos taurus (Bovine) | PR |
| P22451 | RPL5 | 60S ribosomal protein L5 | Gallus gallus (Chicken) | PR |
| P46777 | RPL5 | 60S ribosomal protein L5 | Homo sapiens (Human) | PR |
| P47962 | Rpl5 | 60S ribosomal protein L5 | Mus musculus (Mouse) | PR |
| P09895 | Rpl5 | 60S ribosomal protein L5 | Rattus norvegicus (Rat) | PR |
| P49405 | rpl-5 | 60S ribosomal protein L5 | Caenorhabditis elegans | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGFVKVVKNK | QYFKRYQVKF | KRRREGKTDY | YARKRLVVQD | KNKYNTPKYR | LIVRLSNKDV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TCQVAYSRIE | GDHIVCAAYS | HELPRYGVKV | GLTNYAAAYS | TGLLLARRLL | QRLGLDTLYT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GTTDVTGDEY | NVEPVDNGPG | AFRCYLDVGL | ARTTTGRRVF | GAMKGAVDGG | LNVPHSIKRF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PGYDAESKKF | NAEVHRAHIF | GLHVAEYMRS | LEQDDEDSFK | RQFSKYIKLG | VTADAIEAIY |
| 250 | 260 | 270 | 280 | 290 | |
| KKAHEAIRAD | PSHKKKELKK | DSVKQKRWNK | RKLTLAERKN | RIKQKKASFI | KRLQAQAEA |