P46777
PR
Gene name |
RPL5 (MSTP030) |
Protein name |
60S ribosomal protein L5 |
Names |
Large ribosomal subunit protein uL18 |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:6125 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
85 structures for P46777
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 4UG0 | EM | - | LD | 1-297 | PDB |
| 4V6X | EM | 500 A | CD | 1-297 | PDB |
| 5AJ0 | EM | 350 A | AD | 1-297 | PDB |
| 5LKS | EM | 360 A | LD | 1-297 | PDB |
| 5T2C | EM | 360 A | G | 1-297 | PDB |
| 6IP5 | EM | 390 A | 1G | 1-297 | PDB |
| 6IP6 | EM | 450 A | 1G | 1-297 | PDB |
| 6IP8 | EM | 390 A | 1G | 1-297 | PDB |
| 6LQM | EM | 309 A | r | 1-297 | PDB |
| 6LSR | EM | 313 A | r | 1-297 | PDB |
| 6LSS | EM | 323 A | r | 1-297 | PDB |
| 6LU8 | EM | 313 A | r | 1-297 | PDB |
| 6OLE | EM | 310 A | F | 4-297 | PDB |
| 6OLF | EM | 390 A | F | 4-297 | PDB |
| 6OLG | EM | 340 A | AD | 4-297 | PDB |
| 6OLI | EM | 350 A | F | 4-297 | PDB |
| 6OLZ | EM | 390 A | AD | 4-297 | PDB |
| 6OM0 | EM | 310 A | F | 4-297 | PDB |
| 6OM7 | EM | 370 A | F | 4-297 | PDB |
| 6QZP | EM | 290 A | LD | 2-294 | PDB |
| 6W6L | EM | 384 A | F | 1-297 | PDB |
| 6XA1 | EM | 280 A | LD | 2-291 | PDB |
| 6Y0G | EM | 320 A | LD | 1-297 | PDB |
| 6Y2L | EM | 300 A | LD | 1-297 | PDB |
| 6Y57 | EM | 350 A | LD | 1-297 | PDB |
| 6Y6X | EM | 280 A | LD | 2-294 | PDB |
| 6Z6L | EM | 300 A | LD | 1-297 | PDB |
| 6Z6M | EM | 310 A | LD | 1-297 | PDB |
| 6Z6N | EM | 290 A | LD | 1-297 | PDB |
| 6ZM7 | EM | 270 A | LD | 1-297 | PDB |
| 6ZME | EM | 300 A | LD | 1-297 | PDB |
| 6ZMI | EM | 260 A | LD | 1-297 | PDB |
| 6ZMO | EM | 310 A | LD | 1-297 | PDB |
| 7BHP | EM | 330 A | LD | 1-297 | PDB |
| 7F5S | EM | 272 A | LD | 1-297 | PDB |
| 7OW7 | EM | 220 A | G | 1-297 | PDB |
| 7QVP | EM | 300 A | LD/MD | 1-297 | PDB |
| 7XNX | EM | 270 A | LD | 1-297 | PDB |
| 7XNY | EM | 250 A | LD | 1-297 | PDB |
| 8A3D | EM | 167 A | G | 1-297 | PDB |
| 8BGU | EM | 410 A | A | 1-297 | PDB |
| 8FL0 | EM | 291 A | SB | 1-297 | PDB |
| 8FL2 | EM | 267 A | SB | 1-297 | PDB |
| 8FL3 | EM | 253 A | SB | 1-297 | PDB |
| 8FL4 | EM | 289 A | SB | 1-297 | PDB |
| 8FL6 | EM | 262 A | SB | 1-297 | PDB |
| 8FL7 | EM | 255 A | SB | 1-297 | PDB |
| 8FL9 | EM | 275 A | SB | 1-297 | PDB |
| 8FLA | EM | 263 A | SB | 1-297 | PDB |
| 8FLB | EM | 255 A | SB | 1-297 | PDB |
| 8FLC | EM | 276 A | SB | 1-297 | PDB |
| 8FLD | EM | 258 A | SB | 1-297 | PDB |
| 8FLE | EM | 248 A | SB | 1-297 | PDB |
| 8FLF | EM | 265 A | SB | 1-297 | PDB |
| 8G5Y | EM | 229 A | LD | 1-297 | PDB |
| 8G5Z | EM | 264 A | LD | 2-295 | PDB |
| 8G60 | EM | 254 A | LD | 1-297 | PDB |
| 8G61 | EM | 294 A | LD | 1-297 | PDB |
| 8G6J | EM | 280 A | LD | 1-297 | PDB |
| 8GLP | EM | 167 A | LD | 1-297 | PDB |
| 8IDT | EM | 280 A | r | 1-297 | PDB |
| 8IDY | EM | 300 A | r | 1-297 | PDB |
| 8IE3 | EM | 330 A | r | 1-297 | PDB |
| 8IFD | EM | 259 A | 1G | 1-297 | PDB |
| 8IFE | EM | 257 A | 1G | 1-297 | PDB |
| 8INE | EM | 320 A | r | 1-297 | PDB |
| 8INF | EM | 300 A | r | 1-297 | PDB |
| 8INK | EM | 320 A | R | 1-297 | PDB |
| 8IPD | EM | 320 A | R | 1-297 | PDB |
| 8IPX | EM | 430 A | R | 1-297 | PDB |
| 8IPY | EM | 320 A | R | 1-297 | PDB |
| 8IR1 | EM | 330 A | C | 1-297 | PDB |
| 8IR3 | EM | 350 A | C | 1-297 | PDB |
| 8JDJ | EM | 250 A | J | 1-297 | PDB |
| 8JDK | EM | 226 A | J | 1-297 | PDB |
| 8JDL | EM | 242 A | J | 1-297 | PDB |
| 8JDM | EM | 267 A | J | 1-297 | PDB |
| 8OHD | EM | 310 A | LD | 1-297 | PDB |
| 8OJ0 | EM | 330 A | LD | 1-297 | PDB |
| 8OJ5 | EM | 290 A | LD | 1-297 | PDB |
| 8OJ8 | EM | 330 A | LD | 1-297 | PDB |
| 8QFD | EM | 220 A | D | 1-297 | PDB |
| 8Y0W | EM | 340 A | LD | 1-297 | PDB |
| 8Y0X | EM | 330 A | LD | 1-297 | PDB |
| AF-P46777-F1 | Predicted | AlphaFoldDB |
249 variants for P46777
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
RCV001044815 rs1686990557 |
3 | F>missing | Diamond-Blackfan anemia [ClinVar] | Yes |
ClinVar dbSNP |
|
rs1686990676 RCV001056294 |
6 | V>missing | Diamond-Blackfan anemia [ClinVar] | Yes |
ClinVar dbSNP |
|
rs1686991615 RCV001220057 |
12 | Y>C | Diamond-Blackfan anemia [ClinVar] | Yes |
ClinVar dbSNP |
|
rs1686991727 RCV001267131 |
14 | K>missing | Inborn genetic diseases [ClinVar] | Yes |
ClinVar dbSNP |
|
CA341240733 COSM3401090 RCV000822654 CA26756932 rs148673599 |
16 | Y>* | Variant assessed as Somatic; impact. Diamond-Blackfan anemia central_nervous_system [NCI-TCGA, ClinVar, Cosmic] | Yes |
ClinGen cosmic curated NCI-TCGA TOPMed gnomAD ClinVar dbSNP |
|
RCV000006556 RCV001217229 rs121434405 RCV000627210 CA253786 |
23 | R>* | Diamond-Blackfan anemia Variant assessed as Somatic; impact. Diamond-blackfan anemia 6 (dba6) Diamond-Blackfan anemia 6 [ClinVar, NCI-TCGA, Ensembl] | Yes |
ClinGen ClinVar Ensembl NCI-TCGA dbSNP |
|
CA341240781 rs1558283853 RCV000694413 |
24 | R>* | Diamond-Blackfan anemia [ClinVar] | Yes |
ClinGen ClinVar Ensembl dbSNP |
|
CA952373 rs772575122 RCV001269404 RCV001326298 |
35 | R>C | Diamond-Blackfan anemia Diamond-Blackfan anemia 6 [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
CA341240898 rs1553285006 RCV000626216 |
40 | D>N | Diamond-Blackfan anemia 6 [ClinVar] | Yes |
ClinGen ClinVar Ensembl dbSNP |
|
RCV000466439 CA16610155 rs1060503527 COSM465099 |
44 | Y>* | Diamond-Blackfan anemia kidney [ClinVar, Cosmic] | Yes |
ClinGen cosmic curated ClinVar Ensembl dbSNP |
|
RCV001008074 rs1558284033 RCV000761557 RCV000702906 RCV002249419 |
57 | N>missing | Diamond-Blackfan anemia Diamond-Blackfan anemia 1 Diamond-Blackfan anemia 6 [ClinVar] | Yes |
ClinVar dbSNP |
|
RCV000805012 rs1571024385 |
57 | N>missing | Diamond-Blackfan anemia [ClinVar] | Yes |
ClinVar dbSNP |
|
CA341241059 rs1553285028 RCV000638827 |
57 | N>S | Diamond-Blackfan anemia [ClinVar] | Yes |
ClinGen ClinVar Ensembl dbSNP |
|
RCV000819548 rs1571024430 RCV000006558 |
59 | D>missing | Diamond-Blackfan anemia Diamond-Blackfan anemia 6 [ClinVar] | Yes |
ClinVar dbSNP |
|
RCV000691705 rs1558284062 CA341241101 |
63 | Q>* | Diamond-Blackfan anemia [ClinVar] | Yes |
ClinGen ClinVar Ensembl dbSNP |
|
RCV001850572 RCV000405612 CA952409 rs750383596 |
68 | R>C | Diamond-Blackfan anemia Diamond-Blackfan anemia 6 [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
CA952412 RCV000810118 RCV002495118 rs752867126 |
77 | A>T | Diamond-Blackfan anemia Variant assessed as Somatic; 0.0 impact. Diamond-Blackfan anemia 6 [ClinVar, NCI-TCGA] | Yes |
ClinGen ClinVar ExAC NCI-TCGA dbSNP gnomAD |
|
rs1571026775 RCV000006559 |
79 | Y>missing | Diamond-Blackfan anemia 6 [ClinVar] | Yes |
ClinVar dbSNP |
|
RCV001231388 rs1043234543 RCV002497788 CA26757855 |
79 | Y>N | Diamond-Blackfan anemia Diamond-Blackfan anemia 6 [ClinVar] | Yes |
ClinGen ClinVar TOPMed dbSNP |
|
RCV002444558 RCV000087038 rs587777117 CA267570 |
82 | E>* | Diamond-Blackfan anemia Diamond-blackfan anemia 6 (dba6) Diamond-Blackfan anemia 6 [ClinVar, Ensembl] | Yes |
ClinGen ClinVar Ensembl dbSNP |
|
CA26757888 rs970129317 RCV001314388 |
84 | P>R | Diamond-Blackfan anemia [ClinVar] | Yes |
ClinGen ClinVar TOPMed dbSNP |
|
RCV000543851 rs1553121909 |
86 | Y>missing | Diamond-Blackfan anemia [ClinVar] | Yes |
ClinVar dbSNP |
|
RCV001265621 rs1687054029 |
90 | V>missing | Diamond-Blackfan anemia 6 [ClinVar] | Yes |
ClinVar dbSNP |
|
rs775952185 RCV002487819 RCV000818994 CA952420 |
90 | V>A | Diamond-Blackfan anemia Diamond-Blackfan anemia 6 [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
RCV001321696 rs1687056401 |
106 | A>T | Diamond-Blackfan anemia [ClinVar] | Yes |
ClinVar dbSNP |
|
rs751845365 RCV001210389 CA952432 |
107 | R>H | Diamond-Blackfan anemia [ClinVar] | Yes |
ClinGen ClinVar ExAC dbSNP gnomAD |
|
RCV000229721 CA10581818 rs878854146 |
109 | L>P | Diamond-Blackfan anemia [ClinVar] | Yes |
ClinGen ClinVar Ensembl dbSNP |
|
rs1687120549 RCV001101554 |
134 | S>R | Diamond-Blackfan anemia 6 [ClinVar] | Yes |
ClinVar dbSNP |
|
rs200075817 RCV002059504 CA952458 RCV003151016 RCV000406449 |
135 | I>V | Diamond-Blackfan anemia Diamond-Blackfan anemia 6 [ClinVar] | Yes |
ClinGen ClinVar 1000Genomes ExAC TOPMed dbSNP gnomAD |
|
rs367631074 RCV001308249 |
140 | G>D | Diamond-Blackfan anemia [ClinVar] | Yes |
ClinVar dbSNP |
|
RCV000006557 rs121434406 CA253788 RCV002460888 VAR_055450 RCV000499952 RCV001306122 |
140 | G>S | Diamond-Blackfan anemia Diamond-blackfan anemia 6 (dba6) Diamond-Blackfan anemia 6 DBA6 [ClinVar, Ensembl, UniProt] | Yes |
ClinGen ClinVar UniProt ExAC TOPMed dbSNP gnomAD |
|
rs11540836 RCV002476139 RCV000536846 CA952466 CA26758921 |
142 | F>L | Diamond-Blackfan anemia Diamond-Blackfan anemia 6 [ClinVar] | Yes |
ClinGen ClinVar 1000Genomes ExAC dbSNP gnomAD |
|
rs1687123286 RCV001332618 |
154 | T>* | Diamond-Blackfan anemia 6 [ClinVar] | Yes |
ClinVar dbSNP |
|
RCV000812596 rs1571031819 CA341242951 RCV003151156 |
205 | A>T | Diamond-Blackfan anemia [ClinVar] | Yes |
ClinGen ClinVar Ensembl dbSNP |
|
CA952527 RCV002484225 RCV001226000 rs770095159 |
209 | R>C | Diamond-Blackfan anemia Diamond-Blackfan anemia 6 [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
RCV000233634 RCV000503324 VAR_052009 RCV000513699 RCV001093892 rs11540832 CA952529 RCV000986343 |
210 | Y>C | Diamond-Blackfan anemia Diamond-Blackfan anemia 1 Diamond-Blackfan anemia 6 [ClinVar] | Yes |
ClinGen ClinVar UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
RCV001239349 rs1687178005 |
212 | M>missing | Diamond-Blackfan anemia [ClinVar] | Yes |
ClinVar dbSNP |
|
rs764296257 CA952531 RCV001101555 |
214 | E>D | Diamond-Blackfan anemia 6 [ClinVar] | Yes |
ClinGen ClinVar ExAC dbSNP gnomAD |
|
rs587777118 RCV000087039 CA267572 |
222 | Q>* | Diamond-blackfan anemia 6 (dba6) Diamond-Blackfan anemia 6 [Ensembl, ClinVar] | Yes |
ClinGen ClinVar Ensembl dbSNP |
|
rs767163981 RCV001209210 CA952534 |
222 | Q>H | Diamond-Blackfan anemia [ClinVar] | Yes |
ClinGen ClinVar ExAC dbSNP gnomAD |
|
rs1687179289 RCV001059773 |
225 | Q>P | Diamond-Blackfan anemia [ClinVar] | Yes |
ClinVar dbSNP |
|
rs1571032029 RCV000853337 |
232 | T>missing | Diamond-Blackfan anemia 6 [ClinVar] | Yes |
ClinVar dbSNP |
|
rs576330538 RCV000791214 CA952539 RCV002536927 |
234 | D>G | Diamond-Blackfan anemia Diamond-Blackfan anemia 6 [ClinVar] | Yes |
ClinGen ClinVar 1000Genomes ExAC dbSNP gnomAD |
|
rs938367538 CA16610139 RCV000475823 |
234 | D>Y | Diamond-Blackfan anemia [ClinVar] | Yes |
ClinGen ClinVar TOPMed dbSNP |
|
rs773839391 RCV000365270 CA952558 RCV001410786 |
261 | V>L | Diamond-Blackfan anemia Diamond-Blackfan anemia 6 [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
RCV000689935 COSM3419583 CA952637 rs765443248 |
268 | R>H | Diamond-Blackfan anemia Variant assessed as Somatic; 0.0 impact. large_intestine [ClinVar, NCI-TCGA, Cosmic] | Yes |
ClinGen cosmic curated ClinVar ExAC NCI-TCGA dbSNP gnomAD |
| VAR_055451 | 285 | A>V | DBA6 [UniProt] | Yes | UniProt |
|
RCV000463759 CA16610167 rs1060503545 |
290 | A>T | Diamond-Blackfan anemia [ClinVar] | Yes |
ClinGen ClinVar Ensembl dbSNP |
| TCGA novel | 2 | G>W | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs749504844 CA952351 |
6 | V>I | No |
ClinGen ExAC gnomAD |
|
|
rs749504844 CA341240656 |
6 | V>L | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 8 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs774416689 CA952353 |
11 | A>D | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 15 | R>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs767994083 CA952355 |
17 | Q>P | No |
ClinGen ExAC gnomAD |
|
|
rs1182717955 CA341240778 |
23 | R>Q | No |
ClinGen TOPMed gnomAD |
|
|
CA341240783 rs1198185864 |
24 | R>Q | No |
ClinGen TOPMed |
|
|
rs1351630493 CA341240804 |
26 | G>S | No |
ClinGen TOPMed gnomAD |
|
|
rs774705183 CA952371 |
28 | T>S | No |
ClinGen ExAC gnomAD |
|
|
rs1475427634 CA341240828 |
29 | D>V | No |
ClinGen TOPMed |
|
|
rs748318627 CA952372 |
30 | Y>H | No |
ClinGen ExAC gnomAD |
|
|
rs1236737150 CA341240838 |
31 | Y>N | No |
ClinGen TOPMed |
|
|
rs1294471544 CA341240873 |
36 | L>S | No |
ClinGen gnomAD |
|
|
CA341240894 rs1284275713 |
39 | Q>R | No |
ClinGen TOPMed |
|
|
rs761298943 CA952375 |
40 | D>G | No |
ClinGen ExAC gnomAD |
|
|
CA341240917 rs1558283980 |
42 | N>S | No |
ClinGen Ensembl |
|
|
CA341240937 rs1232329456 |
45 | N>D | No |
ClinGen TOPMed gnomAD |
|
|
CA341240936 rs1232329456 |
45 | N>H | No |
ClinGen TOPMed gnomAD |
|
|
CA952376 rs767035217 |
45 | N>S | No |
ClinGen ExAC gnomAD |
|
|
RCV001268005 rs1687002124 |
48 | K>missing | No |
ClinVar dbSNP |
|
| TCGA novel | 48 | K>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 49 | Y>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1233574565 CA341240964 |
49 | Y>H | No |
ClinGen TOPMed |
|
| TCGA novel | 50 | R>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
COSM1663969 rs1380310694 CA341240986 |
50 | R>S | kidney [Cosmic] | No |
ClinGen cosmic curated TOPMed |
|
COSM1748666 CA952379 rs764649729 |
54 | R>C | Variant assessed as Somatic; 0.0 impact. urinary_tract [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA26757055 rs912779029 |
54 | R>H | No |
ClinGen TOPMed |
|
|
CA952381 rs757996884 |
56 | T>A | No |
ClinGen ExAC gnomAD |
|
|
CA341241062 rs1469578043 |
57 | N>K | No |
ClinGen gnomAD |
|
|
rs1558284048 CA341241073 |
59 | D>A | No |
ClinGen Ensembl |
|
|
CA952382 TCGA novel rs763905952 |
60 | I>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
NCI-TCGA ClinGen ExAC TOPMed gnomAD |
| TCGA novel | 62 | C>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA341241092 rs1456810271 |
62 | C>S | No |
ClinGen TOPMed |
|
|
rs372954310 CA26757071 |
63 | Q>L | No |
ClinGen ESP |
|
|
rs1460207899 CA341241444 |
65 | A>T | No |
ClinGen gnomAD |
|
|
CA341241449 rs1164645812 |
65 | A>V | No |
ClinGen gnomAD |
|
|
rs1402637100 CA341241450 |
66 | Y>N | No |
ClinGen gnomAD |
|
|
CA26757816 rs904664294 |
67 | A>S | No |
ClinGen TOPMed |
|
|
CA952410 rs755960588 |
68 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA341241473 rs1357227822 |
69 | I>M | No |
ClinGen gnomAD |
|
|
rs1231286148 CA341241476 |
70 | E>* | No |
ClinGen gnomAD |
|
|
CA341241474 rs1231286148 |
70 | E>K | No |
ClinGen gnomAD |
|
| TCGA novel | 73 | M>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1206500006 CA341241511 |
74 | I>M | No |
ClinGen gnomAD |
|
|
CA341241509 rs1350991292 |
74 | I>T | No |
ClinGen gnomAD |
|
|
rs1272308261 CA341241506 |
74 | I>V | No |
ClinGen TOPMed gnomAD |
|
|
CA341241520 rs1483322912 |
76 | C>R | No |
ClinGen gnomAD |
|
|
CA952413 rs14361 |
77 | A>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA341241535 rs1474511192 |
78 | A>G | No |
ClinGen TOPMed gnomAD |
|
|
CA16040510 rs1435009501 |
79 | Y>F | No |
ClinGen gnomAD |
|
| TCGA novel | 79 | Y>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 81 | H>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1199764996 CA341241552 |
81 | H>R | No |
ClinGen TOPMed gnomAD |
|
|
rs771331683 CA952416 |
82 | E>D | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA952417 rs781353827 |
86 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
CA26757912 rs11540831 |
89 | K>* | No |
ClinGen Ensembl |
|
|
rs1314815534 CA341241602 |
89 | K>R | No |
ClinGen gnomAD |
|
|
rs371559214 CA952421 |
91 | G>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA gnomAD |
|
CA952422 rs553146536 |
92 | L>P | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA341241635 rs1277412455 |
95 | Y>H | No |
ClinGen gnomAD |
|
| TCGA novel | 95 | Y>W | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1211064485 CA341241642 |
96 | A>T | No |
ClinGen gnomAD |
|
|
CA341241646 rs1281806562 |
96 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs767371010 CA952425 |
97 | A>T | No |
ClinGen ExAC gnomAD |
|
|
rs1251824626 CA341241663 |
99 | Y>C | No |
ClinGen gnomAD |
|
|
CA26757947 rs984455678 |
100 | C>Y | No |
ClinGen TOPMed |
|
|
RCV000722589 CA341241678 rs1557439964 |
101 | T>S | No |
ClinGen ClinVar Ensembl dbSNP |
|
|
CA952429 rs766476007 |
104 | L>V | No |
ClinGen ExAC gnomAD |
|
|
rs777933769 CA952431 |
107 | R>C | No |
ClinGen ExAC gnomAD |
|
|
CA341241709 rs751845365 |
107 | R>L | No |
ClinGen ExAC gnomAD |
|
|
CA26758785 rs878854146 |
109 | L>H | No |
ClinGen Ensembl |
|
| TCGA novel | 109 | L>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs751630540 CA952449 |
110 | L>F | No |
ClinGen ExAC gnomAD |
|
|
rs757337697 CA952450 |
111 | N>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1064793686 RCV000483793 |
112 | R>missing | No |
ClinVar dbSNP |
|
|
CA952452 rs750651869 |
112 | R>K | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 113 | F>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs756437351 CA952453 |
113 | F>S | No |
ClinGen ExAC gnomAD |
|
|
rs962265696 CA26758852 |
114 | G>D | No |
ClinGen gnomAD |
|
|
CA341241936 rs1203679883 |
115 | M>I | No |
ClinGen gnomAD |
|
|
rs1292370167 CA341241946 |
116 | D>E | No |
ClinGen TOPMed |
|
|
rs1221719024 CA341241955 |
118 | I>L | No |
ClinGen TOPMed |
|
|
rs376960219 CA952454 |
119 | Y>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA341241973 rs1215872460 |
120 | E>G | No |
ClinGen TOPMed gnomAD |
|
|
CA341241993 rs1227628823 |
123 | V>L | No |
ClinGen TOPMed |
|
|
rs11540843 CA26758862 |
128 | D>G | No |
ClinGen TOPMed |
|
|
CA341242024 rs1295258351 |
128 | D>Y | No |
ClinGen TOPMed |
|
|
rs539328780 CA26758867 |
130 | Y>F | No |
ClinGen Ensembl |
|
|
rs1347839108 CA341242067 |
131 | N>S | No |
ClinGen TOPMed |
|
|
CA952457 rs779364652 |
132 | V>A | No |
ClinGen ExAC gnomAD |
|
|
rs1571029478 CA341242094 |
133 | E>K | No |
ClinGen Ensembl |
|
|
RCV001268801 rs1687120632 |
135 | I>missing | No |
ClinVar dbSNP |
|
|
CA341242129 rs771599532 |
135 | I>N | No |
ClinGen ExAC gnomAD |
|
|
rs771599532 CA952459 |
135 | I>T | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 136 | D>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs746606485 CA952461 |
137 | G>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs1190811369 CA341242161 |
138 | Q>K | No |
ClinGen gnomAD |
|
|
rs776519108 CA952463 |
139 | P>L | No |
ClinGen ExAC gnomAD |
|
|
rs770863952 CA952462 |
139 | P>S | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 139 | P>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA952464 rs367631074 |
140 | G>A | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs767564815 CA952467 |
143 | T>A | No |
ClinGen ExAC gnomAD |
|
|
rs1278125606 CA341242273 |
145 | Y>C | No |
ClinGen gnomAD |
|
|
CA26758932 rs570656717 |
148 | A>T | No |
ClinGen 1000Genomes |
|
|
CA26758936 rs11540829 |
148 | A>V | No |
ClinGen Ensembl |
|
|
rs12561972 CA26758943 |
149 | G>C | No |
ClinGen Ensembl |
|
| TCGA novel | 149 | G>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 154 | T>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs144294099 CA952469 |
155 | T>I | No |
ClinGen ESP ExAC gnomAD |
|
| TCGA novel | 156 | G>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 157 | N>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA341242449 rs1321402734 |
159 | V>L | No |
ClinGen gnomAD |
|
|
rs766756687 CA952470 |
161 | G>V | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 161 | G>W | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs957088087 CA26758972 |
167 | V>A | No |
ClinGen TOPMed |
|
|
CA952471 rs754245145 |
173 | I>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA341242660 rs1251989135 |
175 | H>D | No |
ClinGen TOPMed |
|
|
rs1262464843 CA341242674 |
176 | S>R | No |
ClinGen gnomAD |
|
|
rs1057520746 CA16603764 RCV000441812 |
179 | R>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ClinVar Ensembl NCI-TCGA dbSNP |
| TCGA novel | 182 | G>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA952520 rs749153960 |
182 | G>D | No |
ClinGen ExAC gnomAD |
|
|
CA341242803 rs1397041399 |
184 | D>Y | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs754720452 CA952521 |
186 | E>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 187 | S>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA341242835 rs1557441782 |
188 | K>R | No |
ClinGen Ensembl |
|
|
CA26759598 rs965247191 |
189 | E>D | No |
ClinGen TOPMed |
|
|
rs1323030006 CA341242844 |
189 | E>G | No |
ClinGen gnomAD |
|
|
CA341242862 rs1252688079 |
191 | N>K | No |
ClinGen TOPMed |
|
|
rs778891633 CA952522 |
192 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs771013653 CA952524 |
196 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA952523 rs528939210 |
196 | R>W | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs776644546 CA952525 |
197 | K>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1293650338 CA341242904 |
198 | H>R | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA26759641 rs773325598 |
200 | M>T | No |
ClinGen TOPMed gnomAD |
|
|
rs1284533624 CA341242955 |
205 | A>G | No |
ClinGen TOPMed |
|
|
rs1207727513 CA341242957 |
206 | D>Y | No |
ClinGen gnomAD |
|
|
rs746120360 CA341242966 |
207 | Y>D | No |
ClinGen ExAC gnomAD |
|
|
rs746120360 CA952526 COSM1344934 |
207 | Y>H | Variant assessed as Somatic; 0.0 impact. oesophagus large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
rs1345401244 CA341242979 |
208 | M>I | No |
ClinGen TOPMed gnomAD |
|
|
COSM913348 rs775560628 CA952528 |
209 | R>H | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs1477777637 CA341243003 |
212 | M>T | No |
ClinGen TOPMed gnomAD |
|
|
CA341243029 rs1168298698 |
215 | D>E | No |
ClinGen TOPMed |
|
|
rs1162896540 CA341243051 |
218 | A>G | No |
ClinGen gnomAD |
|
|
rs1198148348 CA341243068 |
220 | K>N | No |
ClinGen TOPMed |
|
|
CA341243065 rs1385870362 |
220 | K>R | No |
ClinGen TOPMed gnomAD |
|
|
CA952533 rs762357870 |
221 | K>E | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 222 | Q>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA341243088 CA952535 rs749988750 |
223 | F>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed |
|
rs1381141260 CA341243090 |
224 | S>A | No |
ClinGen gnomAD |
|
|
rs755553750 CA952536 |
226 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
COSM2156530 rs1358595009 CA341243104 |
226 | Y>H | Variant assessed as Somatic; 0.0 impact. central_nervous_system [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
COSM913350 rs568863745 CA952538 |
231 | V>I | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
rs1457060815 CA341243151 |
232 | T>I | No |
ClinGen TOPMed |
|
|
rs1055462832 CA26759701 |
235 | M>T | No |
ClinGen TOPMed |
|
|
rs200087538 CA952540 |
235 | M>V | No |
ClinGen ExAC |
|
|
CA341243435 rs775785062 |
236 | M>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs775785062 CA952552 |
236 | M>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA341243454 rs1210456794 |
238 | E>D | No |
ClinGen TOPMed |
|
| rs767332385 | 238 | E>missing | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA341243457 rs1336022942 |
239 | M>V | No |
ClinGen gnomAD |
|
|
CA341243546 rs1342552675 |
245 | A>V | No |
ClinGen TOPMed |
|
|
CA341243547 rs1262302844 |
246 | A>T | No |
ClinGen TOPMed |
|
|
COSM913351 rs749410848 CA952553 |
248 | R>Q | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs769164692 CA952554 |
251 | P>L | No |
ClinGen ExAC gnomAD |
|
|
rs1286445715 CA341243630 |
252 | V>G | No |
ClinGen TOPMed |
|
| TCGA novel | 255 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA341243691 rs1251665065 |
256 | K>N | No |
ClinGen gnomAD |
|
|
rs1416015237 CA341243676 |
256 | K>Q | No |
ClinGen TOPMed |
|
|
CA952557 rs772751064 |
257 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs1177042127 CA341243731 |
260 | E>A | No |
ClinGen gnomAD |
|
|
CA341243725 rs1187773502 |
260 | E>K | No |
ClinGen TOPMed gnomAD |
|
|
CA341243730 rs1187773502 |
260 | E>Q | No |
ClinGen TOPMed gnomAD |
|
|
CA341243739 rs773839391 |
261 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA952559 rs760302814 |
262 | K>E | No |
ClinGen ExAC gnomAD |
|
|
CA26761597 rs765742739 |
262 | K>N | No |
ClinGen ExAC gnomAD |
|
|
rs200715037 CA26761599 |
263 | K>N | No |
ClinGen Ensembl |
|
|
CA341243769 rs1379364559 |
263 | K>R | No |
ClinGen TOPMed gnomAD |
|
|
rs773298130 CA952635 |
266 | W>C | No |
ClinGen ExAC gnomAD |
|
|
rs760642694 CA952636 |
268 | R>C | No |
ClinGen ExAC gnomAD |
|
|
rs752865114 CA952638 |
270 | K>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs947531404 CA26762455 |
271 | M>T | No |
ClinGen Ensembl |
|
|
rs1177452983 CA341244026 |
274 | A>V | No |
ClinGen gnomAD |
|
|
CA952641 rs764283613 |
278 | D>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs764283613 CA952640 |
278 | D>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs781569413 CA341244085 |
279 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA952643 rs781569413 |
279 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA952642 rs757574773 |
279 | R>W | No |
ClinGen ExAC gnomAD |
|
|
CA952644 rs373897566 |
280 | V>A | No |
ClinGen ESP ExAC gnomAD |
|
|
CA341244109 rs1207601883 |
282 | Q>E | No |
ClinGen TOPMed |
|
|
CA26762523 rs921998577 |
286 | S>N | No |
ClinGen TOPMed |
|
| TCGA novel | 289 | R>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA26762528 rs150997222 |
292 | E>K | No |
ClinGen ESP TOPMed |
|
|
CA26762572 rs931986000 |
293 | R>Q | No |
ClinGen TOPMed |
|
|
rs200315052 COSM1344935 CA26762559 |
293 | R>W | large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated 1000Genomes NCI-TCGA TOPMed gnomAD |
|
rs1192640684 CA341244205 |
294 | A>T | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 295 | A>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1332221185 CA341244211 |
295 | A>T | No |
ClinGen TOPMed |
|
| TCGA novel | 296 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 297 | S>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
1 associated diseases with P46777
[MIM: 612561]: Diamond-Blackfan anemia 6 (DBA6)
A form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies. {ECO:0000269|PubMed:19061985, ECO:0000269|PubMed:19191325}. Note=The disease is caused by variants affecting the gene represented in this entry.
Without disease ID
- A form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies. {ECO:0000269|PubMed:19061985, ECO:0000269|PubMed:19191325}. Note=The disease is caused by variants affecting the gene represented in this entry.
1 regional properties for P46777
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Ribosomal protein L5 eukaryotic, C-terminal | 236 - 289 | IPR025607 |
Functions
14 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| cytosolic large ribosomal subunit | The large subunit of a ribosome located in the cytosol. |
| cytosolic ribosome | A ribosome located in the cytosol. |
| endoplasmic reticulum | The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
| extracellular exosome | A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. |
| focal adhesion | A cell-substrate junction that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments. In insects focal adhesion has also been referred to as hemi-adherens junction (HAJ). |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| protein-containing complex | A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. |
| ribonucleoprotein complex | A macromolecular complex that contains both RNA and protein molecules. |
| synapse | The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane. |
7 GO annotations of molecular function
| Name | Definition |
|---|---|
| 5S rRNA binding | Binding to a 5S ribosomal RNA, the smallest RNA constituent of a ribosome. |
| mRNA 3'-UTR binding | Binding to a 3' untranslated region of an mRNA molecule. |
| mRNA 5'-UTR binding | Binding to an mRNA molecule at its 5' untranslated region. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| structural constituent of ribosome | The action of a molecule that contributes to the structural integrity of the ribosome. |
| ubiquitin ligase inhibitor activity | Binds to and stops, prevents or reduces the activity of a ubiquitin ligase. |
| ubiquitin protein ligase binding | Binding to a ubiquitin protein ligase enzyme, any of the E3 proteins. |
12 GO annotations of biological process
| Name | Definition |
|---|---|
| cytoplasmic translation | The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein. |
| negative regulation of protein neddylation | Any process that stops, prevents or reduces the frequency, rate or extent of protein neddylation. |
| negative regulation of ubiquitin protein ligase activity | Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin protein ligase activity. |
| negative regulation of ubiquitin-dependent protein catabolic process | Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin-dependent protein catabolic process. |
| positive regulation of gene expression | Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). |
| positive regulation of translation | Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. |
| protein stabilization | Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation. |
| regulation of signal transduction by p53 class mediator | Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator. |
| ribosomal large subunit assembly | The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit. |
| ribosomal large subunit biogenesis | A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis. |
| rRNA processing | Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. |
| translation | The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. |
6 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q58DW5 | RPL5 | 60S ribosomal protein L5 | Bos taurus (Bovine) | PR |
| P22451 | RPL5 | 60S ribosomal protein L5 | Gallus gallus (Chicken) | PR |
| P47962 | Rpl5 | 60S ribosomal protein L5 | Mus musculus (Mouse) | PR |
| P09895 | Rpl5 | 60S ribosomal protein L5 | Rattus norvegicus (Rat) | PR |
| P49405 | rpl-5 | 60S ribosomal protein L5 | Caenorhabditis elegans | PR |
| O76190 | RpL5 | 60S ribosomal protein L5 | Bombyx mori (Silk moth) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGFVKVVKNK | AYFKRYQVKF | RRRREGKTDY | YARKRLVIQD | KNKYNTPKYR | MIVRVTNRDI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ICQIAYARIE | GDMIVCAAYA | HELPKYGVKV | GLTNYAAAYC | TGLLLARRLL | NRFGMDKIYE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GQVEVTGDEY | NVESIDGQPG | AFTCYLDAGL | ARTTTGNKVF | GALKGAVDGG | LSIPHSTKRF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PGYDSESKEF | NAEVHRKHIM | GQNVADYMRY | LMEEDEDAYK | KQFSQYIKNS | VTPDMMEEMY |
| 250 | 260 | 270 | 280 | 290 | |
| KKAHAAIREN | PVYEKKPKKE | VKKKRWNRPK | MSLAQKKDRV | AQKKASFLRA | QERAAES |