P47011

PR
Gene name
GLG2
Protein name
Glycogenin-2
Names
Glycogen synthesis initiator protein 2, Glycogenin glucosyltransferase 2
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YJL137C
EC number
2.4.1.186: Hexosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

257-380 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P47011

Entry ID Method Resolution Chain Position Source
AF-P47011-F1 Predicted AlphaFoldDB

15 variants for P47011

Variant ID(s) Position Change Description Diseaes Association Provenance
s10-156105 7 I>T No SGRP
s10-155970 52 G>E No SGRP
s10-155738 129 E>D No SGRP
s10-155715 137 Y>F No SGRP
s10-155713 138 P>S No SGRP
s10-155680 149 P>S No SGRP
s10-155622 168 L>S No SGRP
s10-155350 259 R>C No SGRP
s10-155347 260 N>H No SGRP
s10-155212 305 H>Y No SGRP
s10-155206 307 P>S No SGRP
s10-155172 318 K>T No SGRP
s10-155116 337 S>A No SGRP
s10-155092 345 H>Y No SGRP
s10-154993 378 P>T No SGRP

No associated diseases with P47011

2 regional properties for P47011

Type Name Position InterPro Accession
binding_site Aminotransferases, class-I, pyridoxal-phosphate-binding site 276 - 289 IPR004838
domain Aminotransferase, class I/classII 58 - 425 IPR004839

Functions

Description
EC Number 2.4.1.186 Hexosyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

4 GO annotations of molecular function

Name Definition
glycogenin glucosyltransferase activity Catalysis of the reaction: UDP-glucose + glycogenin = UDP + glucosylglycogenin.
glycosyltransferase activity Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).
metal ion binding Binding to a metal ion.
UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + a glucosyl-glycogenin = (1,4-alpha-D-glucosyl)n-glucosyl glucogenin + UDP + H+.

1 GO annotations of biological process

Name Definition
glycogen biosynthetic process The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.

7 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P36143 GLG1 Glycogenin-1 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
P46976 GYG1 Glycogenin-1 Homo sapiens (Human) PR
Q9FZ37 GUX4 Putative UDP-glucuronate:xylan alpha-glucuronosyltransferase 4 Arabidopsis thaliana (Mouse-ear cress) PR
Q8GWW4 GUX2 UDP-glucuronate:xylan alpha-glucuronosyltransferase 2 Arabidopsis thaliana (Mouse-ear cress) PR
Q8W4A7 GUX3 Putative UDP-glucuronate:xylan alpha-glucuronosyltransferase 3 Arabidopsis thaliana (Mouse-ear cress) PR
Q8H1S1 GOLS6 Galactinol synthase 6 Arabidopsis thaliana (Mouse-ear cress) PR
F4JMI5 PGSIP7 Putative glucuronosyltransferase PGSIP7 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MAKKVAICTL LYSRDYLPGA LTLAYQLQKL LKHAVVEDEI TLCLLIEKKL FGDEFKPQEI
70 80 90 100 110 120
ALIRSLFKEI IIIEPLKDQE KSIEKNKANL ELLKRPELSH TLLKARLWEL VQFDQVLFLD
130 140 150 160 170 180
ADTLPLNKEF FEILRLYPEQ TRFQIAAVPD IGWPDMFNTG VLLLIPDLDM ATSLQDFLIK
190 200 210 220 230 240
TVSIDGADQG IFNQFFNPIC NYSKEVLHKV SPLMEWIRLP FTYNVTMPNY GYQSSPAMNF
250 260 270 280 290 300
FQQHIRLIHF IGTFKPWSRN TTDYDDHYYQ LWRSTQRELY SECHLSNYFT HLQLGNIETE
310 320 330 340 350 360
TNFYHEPPCL QDLLNHGKRE NQKHVDLDIT SVDRNASQKS TAEKHDIEKP TSKPQSAFKF
370
DWESTDYLDR VQRAFPKPDT