P36143
Gene name |
GLG1 |
Protein name |
Glycogenin-1 |
Names |
Glycogen synthesis initiator protein 1, Glycogenin glucosyltransferase 1 |
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YKR058W |
EC number |
2.4.1.186: Hexosyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P36143
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P36143-F1 | Predicted | AlphaFoldDB |
19 variants for P36143
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s11-552442 | 11 | L>V | No | SGRP | |
| s11-552569 | 53 | G>D | No | SGRP | |
| s11-552595 | 62 | I>L | No | SGRP | |
| s11-552640 | 77 | N>D | No | SGRP | |
| s11-552736 | 109 | E>K | No | SGRP | |
| s11-552806 | 132 | K>R | No | SGRP | |
| s11-552913 | 168 | A>T | No | SGRP | |
| s11-552946 | 179 | F>I | No | SGRP | |
| s11-553339 | 310 | D>Y | No | SGRP | |
| s11-553417 | 336 | Q>K | No | SGRP | |
| s11-553457 | 349 | A>D | No | SGRP | |
| s11-553594 | 395 | N>D | No | SGRP | |
| s11-553634 | 408 | L>P | No | SGRP | |
| s11-553696 | 429 | E>K | No | SGRP | |
| s11-553798 | 463 | P>A | No | SGRP | |
| s11-553805 | 465 | G>D | No | SGRP | |
| s11-553804 | 465 | G>S | No | SGRP | |
| s11-553849 | 480 | S>P | No | SGRP | |
| s11-554135 | 575 | T>I | No | SGRP |
No associated diseases with P36143
Functions
| Description | ||
|---|---|---|
| EC Number | 2.4.1.186 | Hexosyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| glycogenin glucosyltransferase activity | Catalysis of the reaction: UDP-glucose + glycogenin = UDP + glucosylglycogenin. |
| glycosyltransferase activity | Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor). |
| metal ion binding | Binding to a metal ion. |
| UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity | Catalysis of the reaction: UDP-alpha-D-glucose + a glucosyl-glycogenin = (1,4-alpha-D-glucosyl)n-glucosyl glucogenin + UDP + H+. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| glycogen biosynthetic process | The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues. |
7 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P47011 | GLG2 | Glycogenin-2 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| P46976 | GYG1 | Glycogenin-1 | Homo sapiens (Human) | PR |
| Q9FZ37 | GUX4 | Putative UDP-glucuronate:xylan alpha-glucuronosyltransferase 4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GWW4 | GUX2 | UDP-glucuronate:xylan alpha-glucuronosyltransferase 2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8W4A7 | GUX3 | Putative UDP-glucuronate:xylan alpha-glucuronosyltransferase 3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8H1S1 | GOLS6 | Galactinol synthase 6 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| F4JMI5 | PGSIP7 | Putative glucuronosyltransferase PGSIP7 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MYKKLAIATL | LYSADYLPGV | FALGHQVNKL | LEEAGKKGDI | ETCLIVTTSL | FNGTLSELAK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NILQSIYTKI | VLVEPLNCQE | ESIQKNSENL | ALLERPELSF | ALIKARLWEL | TQFEQVLYLD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SDTLPLNKEF | LKLFDIMSKQ | TTSQVGAIAD | IGWPDMFNSG | VMMLIPDADT | ASVLQNYIFE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NTSIDGSDQG | ILNQFFNQNC | CTDELVKDSF | SREWVQLSFT | YNVTIPNLGY | QSSPAMNYFK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PSIKLIHFIG | KHKPWSLWSQ | KNFIKNEYHD | QWNEVYEEFK | EEHQLNNEVS | KPKISDSDKT |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ETPETITPVD | APPSNEPTTN | QEIDTISTVE | ENVDNQNAEP | VPNSDHSPAP | NPVPLDFTKW |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LTTFINKDHL | TNQPVNESRE | YSKENDNNII | NSSSNRDQES | PPNSTQELNS | SYSVVSTQAD |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SDEHQNAEEE | DSTTDNASNS | GEESHLDDIS | TAASSNNNVS | NQPDGKNFSN | SKENNISVES |
| 490 | 500 | 510 | 520 | 530 | 540 |
| SPSNPEQKRS | TDNIQKPSVS | TNDLPDDVEP | HTSVDDNIQY | LEKDKEGYEE | FLPDVYESNA |
| 550 | 560 | 570 | 580 | 590 | 600 |
| IDNEEEFFDD | DARDATEGET | KTSAVADKQE | DMKLTAEETN | QPQQEMPNFK | FDWEDSDYLS |
| 610 | |||||
| KVERCFPDDI | FEYAVE |