P43672
Gene name |
uup |
Protein name |
ATP-binding protein Uup |
Names |
|
Species |
Escherichia coli (strain K12) |
KEGG Pathway |
eco:b0949 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for P43672
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 2LW1 | NMR | - | A | 528-635 | PDB |
| AF-P43672-F1 | Predicted | AlphaFoldDB |
No variants for P43672
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P43672 | |||||
No associated diseases with P43672
8 regional properties for P43672
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | ABC transporter-like, ATP-binding domain | 1 - 253 | IPR003439-1 |
| domain | ABC transporter-like, ATP-binding domain | 320 - 546 | IPR003439-2 |
| domain | AAA+ ATPase domain | 28 - 230 | IPR003593-1 |
| domain | AAA+ ATPase domain | 344 - 514 | IPR003593-2 |
| conserved_site | ABC transporter-like, conserved site | 157 - 171 | IPR017871-1 |
| conserved_site | ABC transporter-like, conserved site | 441 - 455 | IPR017871-2 |
| domain | ABC transporter Uup, C-terminal | 561 - 629 | IPR032524 |
| domain | ABC-transporter extension domain | 224 - 293 | IPR032781 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| ribosome binding | Binding to a ribosome. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| postreplication repair | The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication. Includes pathways that remove replication-blocking lesions in conjunction with DNA replication. |
| regulation of transposon integration | Any process that modulates the frequency, rate or extent of regulation of transposon integration, a process in which a transposable element is incorporated into another DNA molecule. |
| response to radiation | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation. |
7 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P16521 | YEF3 | Elongation factor 3A | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| P0A9U3 | ybiT | Probable ATP-binding protein YbiT | Escherichia coli (strain K12) | PR |
| Q8NE71 | ABCF1 | ATP-binding cassette sub-family F member 1 | Homo sapiens (Human) | PR |
| Q9NUQ8 | ABCF3 | ATP-binding cassette sub-family F member 3 | Homo sapiens (Human) | PR |
| Q8K268 | Abcf3 | ATP-binding cassette sub-family F member 3 | Mus musculus (Mouse) | PR |
| Q9FIB4 | ABCF2 | ABC transporter F family member 2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LV93 | ABCF5 | ABC transporter F family member 5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSLISMHGAW | LSFSDAPLLD | NAELHIEDNE | RVCLVGRNGA | GKSTLMKILN | REQGLDDGRI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IYEQDLIVAR | LQQDPPRNVE | GSVYDFVAEG | IEEQAEYLKR | YHDISRLVMN | DPSEKNLNEL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AKVQEQLDHH | NLWQLENRIN | EVLAQLGLDP | NVALSSLSGG | WLRKAALGRA | LVSNPRVLLL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DEPTNHLDIE | TIDWLEGFLK | TFNGTIIFIS | HDRSFIRNMA | TRIVDLDRGK | LVTYPGNYDQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| YLLEKEEALR | VEELQNAEFD | RKLAQEEVWI | RQGIKARRTR | NEGRVRALKA | MRRERGERRE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VMGTAKMQVE | EASRSGKIVF | EMEDVCYQVN | GKQLVKDFSA | QVLRGDKIAL | IGPNGCGKTT |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LLKLMLGQLQ | ADSGRIHVGT | KLEVAYFDQH | RAELDPDKTV | MDNLAEGKQE | VMVNGKPRHV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LGYLQDFLFH | PKRAMTPVRA | LSGGERNRLL | LARLFLKPSN | LLILDEPTND | LDVETLELLE |
| 490 | 500 | 510 | 520 | 530 | 540 |
| ELIDSYQGTV | LLVSHDRQFV | DNTVTECWIF | EGGGKIGRYV | GGYHDARGQQ | EQYVALKQPA |
| 550 | 560 | 570 | 580 | 590 | 600 |
| VKKTEEAAAA | KAETVKRSSS | KLSYKLQREL | EQLPQLLEDL | EAKLEALQTQ | VADASFFSQP |
| 610 | 620 | 630 | |||
| HEQTQKVLAD | MAAAEQELEQ | AFERWEYLEA | LKNGG |