Q8K268

PR
Gene name
Abcf3
Protein name
ATP-binding cassette sub-family F member 3
Names
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:27406
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

91-190 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8K268

Entry ID Method Resolution Chain Position Source
AF-Q8K268-F1 Predicted AlphaFoldDB

40 variants for Q8K268

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3389586126 3 T>S No EVA
rs3389375744 37 V>L No EVA
rs3389375818 45 G>W No EVA
rs3389368019 47 L>I No EVA
rs3389367983 49 Q>H No EVA
rs3389375803 54 D>N No EVA
rs3389367956 108 G>* No EVA
rs3389409876 111 K>* No EVA
rs257611169 146 S>N No EVA
rs3389398228 193 L>M No EVA
rs3389355947 224 A>S No EVA
rs3389401027 258 D>Y No EVA
rs250085715 260 V>I No EVA
rs3389322998 275 I>N No EVA
rs3389423077 296 E>* No EVA
rs3389375755 296 E>D No EVA
rs3389423070 303 A>T No EVA
rs3389367955 311 L>R No EVA
rs3389400090 327 E>K No EVA
rs3389375806 368 N>Y No EVA
rs3389407475 372 T>K No EVA
rs3389409859 378 L>P No EVA
rs3412846173 379 V>L No EVA
rs3406787066 400 Q>R No EVA
rs3389416134 475 E>* No EVA
rs3389400981 499 F>L No EVA
rs3389367982 508 F>V No EVA
rs3389416090 524 V>D No EVA
rs3389413310 542 L>V No EVA
rs3389400078 581 K>E No EVA
rs3389323000 586 P>S No EVA
rs3389401049 587 E>* No EVA
rs3389323022 588 E>* No EVA
rs3389398241 591 R>C No EVA
rs3389407518 628 C>Y No EVA
rs3389409829 647 E>D No EVA
rs3407056966 648 A>V No EVA
rs3389423129 663 V>I No EVA
rs3389367993 665 H>Q No EVA
rs3389400048 671 R>Q No EVA

No associated diseases with Q8K268

7 regional properties for Q8K268

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 178 - 424 IPR003439-1
domain ABC transporter-like, ATP-binding domain 492 - 707 IPR003439-2
domain AAA+ ATPase domain 202 - 401 IPR003593-1
domain AAA+ ATPase domain 517 - 684 IPR003593-2
conserved_site ABC transporter-like, conserved site 328 - 342 IPR017871-1
conserved_site ABC transporter-like, conserved site 611 - 625 IPR017871-2
domain ABC-transporter extension domain 395 - 473 IPR032781

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

1 GO annotations of biological process

Name Definition
defense response to virus Reactions triggered in response to the presence of a virus that act to protect the cell or organism.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P0A9U3 ybiT Probable ATP-binding protein YbiT Escherichia coli (strain K12) PR
P43672 uup ATP-binding protein Uup Escherichia coli (strain K12) PR
Q9NUQ8 ABCF3 ATP-binding cassette sub-family F member 3 Homo sapiens (Human) PR
10 20 30 40 50 60
MATCADILRS EFPEIDGQVF DYVTGVLHSG SADFESVDDL VEAVGELLQE VSGDSKDDAG
70 80 90 100 110 120
IRAVCQRMYN TLRLAEPQNQ GNSQVLLDAP IQLSKIMENY DCDTKLPGLL KREQSSTVNA
130 140 150 160 170 180
KKLEKAEARL KAKQEKRSEK ETLKTSNPLV LEEASASQAG SRKESRLESS GKNKSYDVRI
190 200 210 220 230 240
ENFDVSFGDR VLLAGADVNL AWGRRYGLVG RNGLGKTTLL KMLATRSLRV PAHISLLHVE
250 260 270 280 290 300
QEVAGDDTPA LQSVLESDTV REDLLRQERE LSLRIAAGRA EGSEAAQLAE IYGKLEEIEA
310 320 330 340 350 360
DKAPARASVI LAGLGFTPKM QQQPTREFSG GWRMRLALAR ALFARPDLLL LDEPTNMLDV
370 380 390 400 410 420
RAILWLENYL QTWPSTILVV SHDRNFLNAI ATDIIHLHSQ RLDGYRGDFE TFIKSKQERL
430 440 450 460 470 480
LNQQREYEAQ QQYRQHIQVF IDRFRYNANR ASQVQSKLKM LEKLPELKPV DKESEVVLKF
490 500 510 520 530 540
PDGFEKFSPP ILQLDEVDFY YDPKHSIFSR LSVSADLESR ICVVGENGAG KSTMLKLLMG
550 560 570 580 590 600
DLSPVRGIRH AHRNLKIGYF SQHHVEQLDL NVSAVELLAR KFPGLPEEEY RHQLGRYGIS
610 620 630 640 650 660
GELAMRPVAS LSGGQKSRVA FAQMTMPCPN FYILDEPTNH LDMETIEALG QALNNFRGGV
670 680 690 700
ILVSHDERFI RLVCKELWVC ENGSVTRVEG GFDQYRALLQ EQFRREGFL