Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9FIB4

Entry ID Method Resolution Chain Position Source
AF-Q9FIB4-F1 Predicted AlphaFoldDB

57 variants for Q9FIB4

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_5_3100228_G_A 5 T>M No 1000Genomes
tmp_5_3100222_A_C 7 L>R No 1000Genomes
ENSVATH00614010 8 Y>H No 1000Genomes
ENSVATH10673523 44 N>I No 1000Genomes
ENSVATH00614009 52 A>T No 1000Genomes
ENSVATH06946123 81 S>L No 1000Genomes
ENSVATH03041896 90 S>I No 1000Genomes
tmp_5_3099863_T_C 127 R>G No 1000Genomes
ENSVATH06946122 127 R>K No 1000Genomes
tmp_5_3099860_T_C 128 I>V No 1000Genomes
ENSVATH06946121 145 P>S No 1000Genomes
tmp_5_3099715_A_G 176 M>T No 1000Genomes
tmp_5_3099680_C_T 188 A>T No 1000Genomes
ENSVATH13974967 193 V>D No 1000Genomes
tmp_5_3099651_T_G 197 E>D No 1000Genomes
tmp_5_3099653_C_G 197 E>Q No 1000Genomes
tmp_5_3099649_A_T 198 L>Q No 1000Genomes
tmp_5_3099595_A_T 216 V>D No 1000Genomes
ENSVATH10673520 282 E>D No 1000Genomes
ENSVATH03041895 288 L>F No 1000Genomes
tmp_5_3099292_C_T 293 V>M No 1000Genomes
tmp_5_3099221_T_A 316 E>D No 1000Genomes
ENSVATH06946118 317 M>K No 1000Genomes
ENSVATH06946117 322 T>A No 1000Genomes
ENSVATH13974966 323 F>S No 1000Genomes
ENSVATH00614005 353 E>D No 1000Genomes
tmp_5_3099085_G_T 362 L>I No 1000Genomes
ENSVATH13974965 369 G>S No 1000Genomes
ENSVATH06946115 375 E>G No 1000Genomes
tmp_5_3098955_T_C 382 Q>R No 1000Genomes
tmp_5_3098881_C_T 407 G>R No 1000Genomes
ENSVATH06946111 424 M>I No 1000Genomes
ENSVATH00614004 428 K>E No 1000Genomes
tmp_5_3098722_T_C 433 I>V No 1000Genomes
ENSVATH06946110 435 R>K No 1000Genomes
tmp_5_3098698_T_C 441 I>V No 1000Genomes
tmp_5_3098653_T_G 456 I>L No 1000Genomes
ENSVATH06946109 456 I>T No 1000Genomes
tmp_5_3098650_T_C 457 M>V No 1000Genomes
tmp_5_3098603_G_C 472 H>Q No 1000Genomes
ENSVATH10673518 472 H>R No 1000Genomes
tmp_5_3098593_G_A 476 P>S No 1000Genomes
tmp_5_3098450_C_T 499 E>K No 1000Genomes
ENSVATH06946108 503 D>N No 1000Genomes
ENSVATH06946106 525 R>K No 1000Genomes
tmp_5_3098184_T_C,G 562 I>M No 1000Genomes
ENSVATH06946102 573 N>K No 1000Genomes
ENSVATH06946101 612 N>D No 1000Genomes
tmp_5_3097843_A_G 613 Y>H No 1000Genomes
tmp_5_3097840_A_G
tmp_5_3097838_G_C
614 F>L No 1000Genomes
tmp_5_3097810_T_C 624 R>G No 1000Genomes
ENSVATH06946096 636 A>T No 1000Genomes
tmp_5_3097771_G_C 637 P>A No 1000Genomes
ENSVATH06946095 658 M>I No 1000Genomes
ENSVATH06946094 659 K>N No 1000Genomes
ENSVATH13974883 665 K>I No 1000Genomes
ENSVATH00614002 676 R>S No 1000Genomes

No associated diseases with Q9FIB4

7 regional properties for Q9FIB4

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 84 - 342 IPR003439-1
domain ABC transporter-like, ATP-binding domain 411 - 626 IPR003439-2
domain AAA+ ATPase domain 108 - 323 IPR003593-1
domain AAA+ ATPase domain 435 - 603 IPR003593-2
conserved_site ABC transporter-like, conserved site 246 - 260 IPR017871-1
conserved_site ABC transporter-like, conserved site 530 - 544 IPR017871-2
domain ABC-transporter extension domain 313 - 400 IPR032781

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
mRNA binding Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P0A9U3 ybiT Probable ATP-binding protein YbiT Escherichia coli (strain K12) PR
P43672 uup ATP-binding protein Uup Escherichia coli (strain K12) PR
Q9LV93 ABCF5 ABC transporter F family member 5 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MVLTTNLYSL NLRSTFFFTN TITCPTLFTF KLSSVSNPRR VFPNIRAHVS AASSNSELES
70 80 90 100 110 120
LLSTDRKLIS KQSNNGASSI SSGVRLENIS KSYEGITVLK DVTWEVKKGE KVGLIGVNGA
130 140 150 160 170 180
GKTTQLRIIT GQEEPDSGNV IWAKPNLKVA FLSQEFEVSM GKTVKEEFMC TFKEEMEIAR
190 200 210 220 230 240
KLENLQKAIE EAVDDLELMG KLLDEFDLLQ RRAQEVDLDS IHAKISKLMS ELGFVSEDAD
250 260 270 280 290 300
RLVASFSSGW QMRMSLGKIL LQNPDLLLLD EPTNHLDLDT IEWLEGYLIK QDVPMVIISH
310 320 330 340 350 360
DRAFLDQLCT KIVETEMGVS RTFDGNYSQY VISKAELVEA QYAAWEKQQK EIEATKDLIS
370 380 390 400 410 420
RLSAGANSGR ASSAEKKLEK LQEEELIEKP FQRKQMKIRF PECGLSGRSV VTVKNLVFGF
430 440 450 460 470 480
DDKMLFNKAN LAIERGEKVA IIGPNGCGKS TLLKLIMGLE KPMRGEVILG EHNVLPNYFE
490 500 510 520 530 540
QNQAEAQDLD KTVIETVVEA AVDWRIDDIK ALLGRCNFKA DMLDRKVSLL SGGEKARLAF
550 560 570 580 590 600
CKFMVKPSTL LVLDEPTNHL DIPSKEMLEE AINEYKGTVI TVSHDRYFIK QIVNRVIEVR
610 620 630 640 650 660
DGGLMDYAGD YNYFLEKNVE ARARELEREA ELEEKAPKVK AKSKMSKAER EARKKQKMKA
670
FQASKKKSKS SKNAKRWN