P38419

PR
Gene name
CM-LOX1 (LOX2.1)
Protein name
Lipoxygenase 7, chloroplastic
Names
Species
Oryza sativa subsp japonica (Rice)
KEGG Pathway
osa:4345993
EC number
1.13.11.12: With incorporation of two atoms of oxygen
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-96 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P38419

Entry ID Method Resolution Chain Position Source
AF-P38419-F1 Predicted AlphaFoldDB

No variants for P38419

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P38419

No associated diseases with P38419

1 regional properties for P38419

Type Name Position InterPro Accession
domain Anaphase-promoting complex subunit 4, long domain 225 - 407 IPR024790

Functions

Description
EC Number 1.13.11.12 With incorporation of two atoms of oxygen
Subcellular Localization
  • Plastid, chloroplast
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
chloroplast A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

4 GO annotations of molecular function

Name Definition
linoleate 13S-lipoxygenase activity Catalysis of the reaction: linoleate + O2 = (9Z,11E)-(13S)-13-hydroperoxyoctadeca-9,11-dienoate.
metal ion binding Binding to a metal ion.
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and two oxygen atoms is incorporated into a donor.
phytoene dehydrogenase activity Catalysis of the dehydrogenation of phytoene to produce a carotenoid intermediate such as phytofluene.

5 GO annotations of biological process

Name Definition
fatty acid biosynthetic process The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
lipid oxidation The removal of one or more electrons from a lipid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen.
oxylipin biosynthetic process The chemical reactions and pathways resulting in the formation of any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids.
response to other organism Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism.
response to wounding Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.

6 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P16050 ALOX15 Polyunsaturated fatty acid lipoxygenase ALOX15 Homo sapiens (Human) PR
P09186 LOX1.3 Seed linoleate 9S-lipoxygenase-3 Glycine max (Soybean) (Glycine hispida) PR
Q06327 LOX1 Linoleate 9S-lipoxygenase 1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FNX8 LOX4 Lipoxygenase 4, chloroplastic Arabidopsis thaliana (Mouse-ear cress) PR
Q9LUW0 LOX5 Linoleate 9S-lipoxygenase 5 Arabidopsis thaliana (Mouse-ear cress) PR
P38418 LOX2 Lipoxygenase 2, chloroplastic Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MLRPQLNPSS HTTTTSSSSS TQLFASSSCI ASLRRPSSSS SSVVAAARRT RGQGSSRVVV
70 80 90 100 110 120
VCASSSATAS RGDSSSDMAA AAAVRVKAVA TIKVTVGELI NRSIDIRDLI GRSLSLELVS
130 140 150 160 170 180
SELDAKTGKE KATVRSYAHN VDDDDHSVVT YEADFDVPSG FGPIGAIIVT NELRQEMFLE
190 200 210 220 230 240
DINLTASDGA GNSTVLPIRC NSWVQPKSVG DEGTPSKRIF FANKTYLPGQ TPAGLRSYRK
250 260 270 280 290 300
NDLQQKRGDG TGEREADDRV YDYDVYNDLG NPDSNGDLAR PVLGGNKQFP YPRRCRTGRP
310 320 330 340 350 360
PSKKDPKSET RKGNVYVPRD EEFSPEKEDY FLRKTVGSVL QAAVPAAQSL LLDKLKWNLP
370 380 390 400 410 420
FPSFFVIDKL FEDGVELPGV DKLNFLESVV PRLLEHLRDT PAEKILRFET PANIQKDKFA
430 440 450 460 470 480
WLRDEEFARE TLAGINPYAI ELVREFPLKS KLDPAVYGPA ESAITADLLE EQMRRVMTVE
490 500 510 520 530 540
EAISQKRLFM LDFHDLFLPY VHKIRSLDHT TMYGSRTVFF LTDDGTLQLL AIELTRPASP
550 560 570 580 590 600
SQPQWRQVFT PSTDATMSWL WRMAKAHVRA HDAGHHELIT HWLRTHCAVE PYIIAANRQL
610 620 630 640 650 660
SEMHPIYQLL RPHFRYTMRI NARARSALIS AGGIIERSFS PQKYSMELSS VAYDKLWRFD
670 680 690 700 710 720
TEALPADLVR RGMAEEDPTA EHGLKLAIED YPFANDGLLI WDAIKTWVQA YVARFYPDAD
730 740 750 760 770 780
SVAGDEELQA FWTEVRTKGH GDKKDAPWWP KLDSPESLAH TLTTIVWVAA AHHAAVNFGQ
790 800 810 820 830 840
YDFGGYFPNR PSIARTVMPV EEPVDGAAME RFLDNPDQAL RECFPSQVQA TVVMAVLDVL
850 860 870 880 890 900
SSHSTDEEYL GGEQTRPWNS DAAVQAAYDG FAARLKEIEG VIDGRNKDRK LKNRCGAGIL
910 920
PYQLMKPFSD SGVTGMGIPN STSI