O15480
PR
Gene name |
MAGEB3 |
Protein name |
Melanoma-associated antigen B3 |
Names |
MAGE-B3 antigen |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:4114 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O15480
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O15480-F1 | Predicted | AlphaFoldDB |
191 variants for O15480
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
rs146770977 CA10375837 |
3 | R>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1243412141 CA412539606 |
3 | R>W | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA412539612 rs1310623383 |
4 | G>A | No |
ClinGen gnomAD |
|
|
rs754935662 CA10375838 |
4 | G>S | No |
ClinGen ExAC gnomAD |
|
|
rs764346553 CA327969622 |
8 | T>A | No |
ClinGen TOPMed gnomAD |
|
|
rs201131077 CA10375839 |
8 | T>M | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs973115670 CA327969648 |
10 | H>Y | No |
ClinGen TOPMed |
|
|
CA412539658 rs1601962136 |
11 | A>E | No |
ClinGen Ensembl |
|
|
TCGA novel CA412539662 rs766493179 |
12 | R>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA 1000Genomes ExAC gnomAD |
|
CA10375842 rs766493179 |
12 | R>G | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA412539664 rs1249140926 |
12 | R>H | No |
ClinGen gnomAD |
|
|
rs912224434 CA327969664 |
14 | K>Q | No |
ClinGen TOPMed |
|
|
CA10375843 rs140421974 |
15 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs370624672 CA10375844 |
15 | R>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA10375845 rs150405296 |
19 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
| TCGA novel | 21 | Q>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA412539730 rs1316757613 |
22 | T>I | No |
ClinGen TOPMed |
|
|
rs769301868 CA10375847 |
24 | D>Y | No |
ClinGen ExAC gnomAD |
|
|
rs777265461 CA10375848 |
25 | H>Q | No |
ClinGen ExAC gnomAD |
|
|
rs868289772 CA327969694 |
26 | Q>R | No |
ClinGen Ensembl |
|
|
CA412539783 rs1569254254 |
30 | I>N | No |
ClinGen Ensembl |
|
|
rs202246584 CA10375849 |
31 | T>I | No |
ClinGen ESP ExAC gnomAD |
|
| TCGA novel | 41 | S>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA412539870 rs1287901576 |
43 | P>S | No |
ClinGen gnomAD |
|
| TCGA novel | 45 | I>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10375854 rs773912188 |
47 | G>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA412539907 rs1442257910 |
49 | T>A | No |
ClinGen gnomAD |
|
|
CA412539913 rs1460266523 |
50 | I>F | No |
ClinGen gnomAD |
|
|
rs182812872 CA327969738 |
50 | I>N | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs182812872 CA10375855 |
50 | I>T | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA10375856 rs767498329 |
53 | K>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs145229582 CA10375857 |
54 | S>P | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 54 | S>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 55 | A>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10375858 rs755941263 |
55 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA412539953 rs1569254284 |
56 | G>A | No |
ClinGen Ensembl |
|
|
CA10375859 rs763926751 |
57 | R>K | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 58 | S>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs758651543 CA10375861 |
59 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs780082636 CA10375862 |
59 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs747172967 CA10375864 |
65 | P>A | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 65 | P>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10375863 rs747172967 |
65 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA327969815 rs1010056385 |
67 | R>K | No |
ClinGen TOPMed gnomAD |
|
|
CA412540041 rs1307533813 |
70 | S>F | No |
ClinGen gnomAD |
|
|
rs1411877074 CA412540057 |
73 | T>K | No |
ClinGen gnomAD |
|
|
CA10375869 rs749543764 |
75 | V>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs149158914 CA10375868 |
75 | V>I | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1485729437 CA412540075 |
76 | D>G | No |
ClinGen TOPMed |
|
|
rs1002125262 CA327969833 |
77 | V>F | No |
ClinGen Ensembl |
|
|
rs1205123269 CA412540100 |
80 | K>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs1271829879 CA412540108 |
81 | K>T | No |
ClinGen gnomAD |
|
|
rs1205994945 CA412540124 |
83 | Y>C | No |
ClinGen TOPMed |
|
|
rs1205994945 CA412540122 |
83 | Y>S | No |
ClinGen TOPMed |
|
|
CA412540138 rs1601962352 |
85 | G>E | No |
ClinGen Ensembl |
|
| TCGA novel | 86 | A>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA327969838 rs750532535 |
87 | N>I | No |
ClinGen gnomAD |
|
|
rs187371545 CA10375871 |
90 | I>T | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
| TCGA novel | 91 | E>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs756681502 CA327969846 |
96 | F>L | No |
ClinGen Ensembl |
|
|
rs780480082 CA10375872 |
97 | S>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs958848531 CA327969850 |
99 | G>V | No |
ClinGen TOPMed |
|
|
CA10375873 rs766981324 |
101 | S>A | No |
ClinGen ExAC |
|
|
CA10375874 rs372021808 |
101 | S>Y | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1425739020 CA412540254 |
102 | S>C | No |
ClinGen gnomAD |
|
|
CA10375875 rs777321413 |
103 | T>P | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA10375876 rs763872315 |
104 | V>M | No |
ClinGen ExAC gnomAD |
|
|
rs139231962 CA10375877 |
106 | S>P | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA412540280 rs761502732 |
107 | R>C | No |
ClinGen ExAC gnomAD |
|
|
rs761502732 CA10375878 |
107 | R>G | No |
ClinGen ExAC gnomAD |
|
|
VAR_021360 CA10375879 rs2071308 |
107 | R>H | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA412540288 rs1330761551 |
108 | T>I | No |
ClinGen gnomAD |
|
|
CA10375880 rs375048517 |
110 | P>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA412540303 rs1276939226 |
111 | L>V | No |
ClinGen gnomAD |
|
|
rs2071309 CA412540310 |
112 | I>N | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs2071309 CA412540311 |
112 | I>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs2071309 CA10375881 VAR_021361 |
112 | I>T | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA412540315 rs1228292309 |
113 | M>L | No |
ClinGen TOPMed gnomAD |
|
|
CA412540313 rs1228292309 |
113 | M>V | No |
ClinGen TOPMed gnomAD |
|
|
CA412540328 rs1273188468 |
114 | K>N | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 115 | T>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1447236062 CA412540339 |
116 | N>T | No |
ClinGen TOPMed |
|
|
rs781448360 CA10375882 |
117 | M>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1343592380 CA412540345 |
117 | M>V | No |
ClinGen gnomAD |
|
| TCGA novel | 119 | V>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs982527511 CA327969890 |
120 | Q>H | No |
ClinGen TOPMed |
|
|
CA10375884 rs756645824 |
124 | E>Q | No |
ClinGen ExAC gnomAD |
|
|
rs778080700 CA10375885 |
125 | M>R | No |
ClinGen ExAC gnomAD |
|
|
rs771192209 CA10375887 |
126 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
CA10375886 rs749717727 |
126 | Y>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs745495531 CA10375889 |
128 | M>T | No |
ClinGen ExAC gnomAD |
|
|
CA327969934 rs973572898 |
131 | P>S | No |
ClinGen TOPMed gnomAD |
|
|
CA10375891 rs775011357 |
133 | M>T | No |
ClinGen ExAC gnomAD |
|
|
CA10375890 rs771663707 |
133 | M>V | No |
ClinGen ExAC gnomAD |
|
|
CA412540478 rs1251911330 |
135 | A>V | No |
ClinGen TOPMed |
|
|
CA412540526 rs1325840582 |
142 | Q>P | No |
ClinGen TOPMed gnomAD |
|
|
CA10375892 rs760122075 |
144 | S>G | No |
ClinGen ExAC gnomAD |
|
|
rs768698062 CA10375893 |
145 | H>Y | No |
ClinGen ExAC gnomAD |
|
|
rs776429024 CA10375894 |
146 | K>R | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs761710997 CA10375895 |
150 | P>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs764921111 CA10375896 |
151 | E>K | No |
ClinGen ExAC gnomAD |
|
|
rs975049397 CA327969973 |
154 | K>E | No |
ClinGen Ensembl |
|
| TCGA novel | 156 | A>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| rs34054171 | 156 | A>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 156 | A>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 157 | S>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs750198978 CA10375897 |
158 | F>V | No |
ClinGen ExAC gnomAD |
|
|
CA327969974 rs920953044 |
160 | M>I | No |
ClinGen Ensembl |
|
|
rs1353709613 CA412540653 |
160 | M>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1353709613 CA412540652 |
160 | M>V | No |
ClinGen TOPMed gnomAD |
|
|
CA10375900 rs752834151 |
164 | F>C | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 171 | V>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 177 | S>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA327970029 rs113117104 |
180 | L>I | No |
ClinGen Ensembl |
|
|
rs757687731 CA10375905 |
181 | V>I | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 186 | L>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 186 | L>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10375907 rs746191660 |
188 | N>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA412540854 rs1418864070 |
189 | N>D | No |
ClinGen gnomAD |
|
|
rs183270866 CA10375909 |
192 | V>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA10375910 rs746598074 |
194 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA10375911 rs768021907 |
194 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs137938000 CA10375912 |
196 | R>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 197 | G>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs868499328 CA327970079 |
199 | P>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
rs761681030 CA10375913 |
202 | G>R | No |
ClinGen ExAC |
|
| TCGA novel | 203 | L>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10375915 rs149480290 |
210 | V>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs762774425 CA10375916 |
218 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs145982241 CA10375917 |
218 | A>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs764056422 CA10375920 |
229 | K>N | No |
ClinGen ExAC gnomAD |
|
|
rs1189733701 CA412541133 |
231 | R>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
| TCGA novel | 236 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1294192392 CA412541181 |
237 | K>R | No |
ClinGen TOPMed |
|
| TCGA novel | 245 | R>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA327970162 rs768704846 |
246 | K>M | No |
ClinGen 1000Genomes |
|
| TCGA novel | 248 | I>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs753905186 CA10375921 |
259 | E>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1359034393 CA412541344 |
260 | Y>C | No |
ClinGen TOPMed |
|
| TCGA novel | 261 | R>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA412541350 rs1157280010 |
261 | R>Q | No |
ClinGen TOPMed gnomAD |
|
|
CA412541353 rs1414634870 |
262 | Q>K | No |
ClinGen gnomAD |
|
|
rs757734476 CA10375922 |
264 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1400712914 CA412541373 |
265 | N>D | No |
ClinGen gnomAD |
|
|
CA327970185 rs1044228465 |
265 | N>S | No |
ClinGen TOPMed gnomAD |
|
|
CA412541381 rs1312918581 |
266 | S>G | No |
ClinGen gnomAD |
|
|
rs139917714 CA10375923 |
270 | R>C | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs758758737 CA10375925 |
270 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs139917714 CA10375924 |
270 | R>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA10375926 rs367655472 |
271 | Y>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA412541411 rs1569254667 |
271 | Y>H | No |
ClinGen Ensembl |
|
|
CA412541417 rs1232275908 |
272 | E>K | No |
ClinGen gnomAD |
|
|
rs1254121257 CA412541454 |
277 | P>S | No |
ClinGen gnomAD |
|
|
rs1211559398 CA412541461 |
278 | R>K | No |
ClinGen gnomAD |
|
|
rs1281102372 CA412541474 |
280 | H>Y | No |
ClinGen gnomAD |
|
| TCGA novel | 283 | T>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA412541520 rs1482804227 |
286 | M>T | No |
ClinGen gnomAD |
|
|
rs143379520 CA327970220 |
288 | V>I | No |
ClinGen ESP TOPMed |
|
| TCGA novel | 293 | A>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 298 | T>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 298 | T>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 299 | V>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs754613263 CA10375928 |
301 | S>I | No |
ClinGen ExAC gnomAD |
|
|
rs780602585 CA10375929 |
302 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA412541647 rs1321976299 |
304 | Q>L | No |
ClinGen TOPMed gnomAD |
|
|
rs747632254 CA10375930 |
305 | F>Y | No |
ClinGen ExAC gnomAD |
|
|
CA10375931 rs138581582 RCV000957770 |
306 | W>C | No |
ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
rs1468005064 CA412541669 |
307 | Y>F | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
| TCGA novel | 309 | E>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA412541702 rs1159126372 |
312 | R>G | No |
ClinGen TOPMed |
|
|
CA10375932 rs373510571 |
315 | E>K | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 321 | A>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1396829541 CA412541773 |
322 | A>T | No |
ClinGen gnomAD |
|
|
CA10375935 rs775902386 |
323 | M>T | No |
ClinGen ExAC |
|
|
CA10375934 rs770816792 |
323 | M>V | No |
ClinGen ExAC |
|
|
CA10375936 rs760828097 |
324 | L>R | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 325 | N>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA412541795 rs1332631497 |
325 | N>S | No |
ClinGen gnomAD |
|
|
rs1010020033 CA327970282 |
326 | D>E | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 327 | G>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 332 | G>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA327970285 rs1051956115 |
332 | G>D | No |
ClinGen TOPMed |
|
|
rs377170100 CA10375937 |
334 | K>E | No |
ClinGen ESP ExAC gnomAD |
|
|
rs776655301 CA10375938 |
335 | C>Y | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
CA10375939 rs761939953 |
336 | S>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10375941 rs750900622 |
340 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1209498029 CA412541914 |
342 | S>I | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 342 | S>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs369618374 CA10375943 |
345 | H>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA10375944 rs751914299 |
346 | A>T | No |
ClinGen ExAC |
|
| TCGA novel | 347 | A>= | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
No associated diseases with O15480
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| negative regulation of transcription by RNA polymerase II | Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. |
17 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P43356 | MAGEA2B | Melanoma-associated antigen 2 | Homo sapiens (Human) | PR |
| O15479 | MAGEB2 | Melanoma-associated antigen B2 | Homo sapiens (Human) | PR |
| P43355 | MAGEA1 | Melanoma-associated antigen 1 | Homo sapiens (Human) | PR |
| P43357 | MAGEA3 | Melanoma-associated antigen 3 | Homo sapiens (Human) | PR |
| P43358 | MAGEA4 | Melanoma-associated antigen 4 | Homo sapiens (Human) | PR |
| P43360 | MAGEA6 | Melanoma-associated antigen 6 | Homo sapiens (Human) | PR |
| P43361 | MAGEA8 | Melanoma-associated antigen 8 | Homo sapiens (Human) | PR |
| P43363 | MAGEA10 | Melanoma-associated antigen 10 | Homo sapiens (Human) | PR |
| P43365 | MAGEA12 | Melanoma-associated antigen 12 | Homo sapiens (Human) | PR |
| Q8TD90 | MAGEE2 | Melanoma-associated antigen E2 | Homo sapiens (Human) | PR |
| Q96MG7 | NSMCE3 | Non-structural maintenance of chromosomes element 3 homolog | Homo sapiens (Human) | PR |
| Q9BZ81 | MAGEB5 | Melanoma-associated antigen B5 | Homo sapiens (Human) | PR |
| Q9HAY2 | MAGEF1 | Melanoma-associated antigen F1 | Homo sapiens (Human) | PR |
| P43364 | MAGEA11 | Melanoma-associated antigen 11 | Homo sapiens (Human) | PR |
| Q9UNF1 | MAGED2 | Melanoma-associated antigen D2 | Homo sapiens (Human) | PR |
| Q9Y5V3 | MAGED1 | Melanoma-associated antigen D1 | Homo sapiens (Human) | PR |
| Q96JG8 | MAGED4B | Melanoma-associated antigen D4 | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPRGQKSTLH | AREKRQQTRG | QTQDHQGAQI | TATNKKKVSF | SSPLILGATI | QKKSAGRSRS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ALKKPQRALS | TTTSVDVSYK | KSYKGANSKI | EKKQSFSQGL | SSTVQSRTDP | LIMKTNMLVQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FLMEMYKMKK | PIMKADMLKI | VQKSHKNCFP | EILKKASFNM | EVVFGVDLKK | VDSTKDSYVL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VSKMDLPNNG | TVTRGRGFPK | TGLLLNLLGV | IFMKGNCATE | EKIWEFLNKM | RIYDGKKHFI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FGEPRKLITQ | DLVKLKYLEY | RQVPNSNPAR | YEFLWGPRAH | AETSKMKVLE | FWAKVNKTVP |
| 310 | 320 | 330 | 340 | ||
| SAFQFWYEEA | LRDEEERVQA | AAMLNDGSSA | MGRKCSKAKA | SSSSHA |