A5JV83

PR
Gene name
hspb11
Protein name
Heat shock protein beta-11
Names
Species
Danio rerio (Zebrafish) (Brachydanio rerio)
KEGG Pathway
dre:796767
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

71-205 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A5JV83

Entry ID Method Resolution Chain Position Source
AF-A5JV83-F1 Predicted AlphaFoldDB

No variants for A5JV83

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A5JV83

No associated diseases with A5JV83

3 regional properties for A5JV83

Type Name Position InterPro Accession
conserved_site 14-3-3 protein, conserved site 49 - 59 IPR023409-1
conserved_site 14-3-3 protein, conserved site 221 - 240 IPR023409-2
domain 14-3-3 domain 9 - 252 IPR023410

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
unfolded protein binding Binding to an unfolded protein.

3 GO annotations of biological process

Name Definition
myosin filament organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a filament composed of myosin molecules.
protein refolding The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.
response to heat Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.

6 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P02518 Hsp27 Heat shock protein 27 Drosophila melanogaster (Fruit fly) PR
Q9UJY1 HSPB8 Heat shock protein beta-8 Homo sapiens (Human) PR
P02511 CRYAB Alpha-crystallin B chain Homo sapiens (Human) PR
Q9JK92 Hspb8 Heat shock protein beta-8 Mus musculus (Mouse) PR
Q9EPX0 Hspb8 Heat shock protein beta-8 Rattus norvegicus (Rat) PR
Q20363 sip-1 Stress-induced protein 1 Caenorhabditis elegans PR
10 20 30 40 50 60
MLCPSTFQPH LSPFMDFHWP VRSLWPETRP LFFQFEQEMM RHMQEMRHNM EFMERLHQRI
70 80 90 100 110 120
FDEIDHVSPM TTFKPISFQL GKEGSHYALT LDTQDFSPEE LAVKQVGRKL RVSGKTEKKQ
130 140 150 160 170 180
DDGKGSYSYR CQEFRQEFDL PEDVNPESVS CSLNNGQLQI QAPREGNTVS NERVIPITYT
190 200
PAVKNPALQN SEPENQAVEA EAAEN