A0JJX5

PR
Gene name
SYT4 (SYTD, At5g11100, T5K6.90)
Protein name
Synaptotagmin-4
Names
NTMC2T2.2, Synaptotagmin D
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT5G11100
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

366-461 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A0JJX5

Entry ID Method Resolution Chain Position Source
AF-A0JJX5-F1 Predicted AlphaFoldDB

No variants for A0JJX5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A0JJX5

No associated diseases with A0JJX5

4 regional properties for A0JJX5

Type Name Position InterPro Accession
domain C2 domain 245 - 368 IPR000008-1
domain C2 domain 426 - 545 IPR000008-2
domain Synaptotagmin-like mitochondrial-lipid-binding domain 67 - 251 IPR031468
domain Synaptotagmin, SMP domain 70 - 250 IPR039010

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
lipid binding Binding to a lipid.
metal ion binding Binding to a metal ion.

1 GO annotations of biological process

Name Definition
lipid transport The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.

7 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9BSJ8 ESYT1 Extended synaptotagmin-1 Homo sapiens (Human) PR
Q3TZZ7 Esyt2 Extended synaptotagmin-2 Mus musculus (Mouse) PR
Q3U7R1 Esyt1 Extended synaptotagmin-1 Mus musculus (Mouse) PR
B6ETT4 SYT2 Synaptotagmin-2 Arabidopsis thaliana (Mouse-ear cress) PR
Q7XA06 SYT3 Synaptotagmin-3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SKR2 SYT1 Synaptotagmin-1 Arabidopsis thaliana (Mouse-ear cress) PR
Q5M7N9 esyt3 Extended synaptotagmin-3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
10 20 30 40 50 60
MGFLFGLFIG IAVSFGLVVA FARYSSVRST RRADLAKTIA AFARMTVQDS RKLLPGDFYP
70 80 90 100 110 120
SWVVFSQRQK LNWLNLELEK IWPYVNEAAS ELIKSSVEPV LEQYTPAMLA SLKFSKFTLG
130 140 150 160 170 180
TVAPQFTGVS ILESESGPNG ITMELEMQWD GNPKIVLDVK TLLGVSLPIE VKNIGFTGVF
190 200 210 220 230 240
RLIFKPLVDE FPCFGALSYS LREKKGLDFT LKVIGGELTS IPGISDAIEE TIRDAIEDSI
250 260 270 280 290 300
TWPVRKIIPI LPGDYSDLEL KPVGKLDVKV VQAKDLANKD MIGKSDPYAI VFIRPLPDRT
310 320 330 340 350 360
KKTKTISNSL NPIWNEHFEF IVEDVSTQHL TVRVFDDEGV GSSQLIGAAQ VPLNELVPGK
370 380 390 400 410 420
VKDIWLKLVK DLEIQRDTKN RGQVQLELLY CPLGKEGGLK NPFNPDYSLT ILEKVLKPES
430 440 450 460 470 480
EDSDATDMKK LVTSKKKDVI VRGVLSVTVV AAEDLPAVDF MGKADAFVVI TLKKSETKSK
490 500 510 520 530 540
TRVVPDSLNP VWNQTFDFVV EDALHDLLTL EVWDHDKFGK DKIGRVIMTL TRVMLEGEFQ
550 560
EWFELDGAKS GKLCVHLKWT PRLKLRDAS