Q9Y512
PR
Gene name |
SAMM50 (SAM50, CGI-51, TRG3) |
Protein name |
Sorting and assembly machinery component 50 homolog |
Names |
Transformation-related gene 3 protein, TRG-3 |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:25813 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
3 structures for Q9Y512
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 6YOO | X-ray | 106 A | B | 24-35 | PDB |
| 6YOP | X-ray | 110 A | A | 24-39 | PDB |
| AF-Q9Y512-F1 | Predicted | AlphaFoldDB |
392 variants for Q9Y512
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
rs1328163131 CA411849556 |
2 | G>R | No |
ClinGen gnomAD |
|
|
rs764674823 CA10278325 |
2 | G>V | No |
ClinGen ExAC gnomAD |
|
|
CA411849575 rs1436049671 CA411849574 |
4 | V>L | No |
ClinGen gnomAD |
|
|
rs1250409708 CA411849582 |
5 | H>Y | No |
ClinGen TOPMed |
|
|
CA10278328 rs369254324 |
7 | R>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA10278326 rs754290245 |
7 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1472538054 CA411849737 |
9 | L>S | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 13 | P>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1453670318 CA411849786 |
14 | S>P | No |
ClinGen gnomAD |
|
|
rs1410525145 CA411849796 |
15 | S>G | No |
ClinGen gnomAD |
|
|
rs773573489 CA10278347 |
16 | G>E | No |
ClinGen ExAC gnomAD |
|
|
CA10278346 rs369884307 |
16 | G>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1363020741 CA411849819 |
17 | P>R | No |
ClinGen gnomAD |
|
|
CA411849823 rs983788832 |
18 | D>H | No |
ClinGen TOPMed gnomAD |
|
|
CA324874610 rs983788832 |
18 | D>N | No |
ClinGen TOPMed gnomAD |
|
|
rs763173401 CA10278348 |
20 | G>V | No |
ClinGen ExAC gnomAD |
|
|
rs767225703 CA10278350 |
23 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10278351 rs200348301 |
24 | E>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1285710009 CA411849969 |
31 | V>A | No |
ClinGen gnomAD |
|
|
rs1382078501 CA411849998 |
34 | E>K | No |
ClinGen TOPMed |
|
|
rs1388793366 CA411850011 |
35 | A>T | No |
ClinGen gnomAD |
|
|
rs1302027319 CA411850069 |
39 | I>S | No |
ClinGen gnomAD |
|
|
rs753886150 CA10278354 |
39 | I>V | No |
ClinGen ExAC gnomAD |
|
|
CA411850078 rs757253689 |
40 | L>F | No |
ClinGen ExAC gnomAD |
|
|
rs757253689 CA10278355 |
40 | L>I | No |
ClinGen ExAC gnomAD |
|
|
CA10278356 rs778925941 |
43 | K>E | No |
ClinGen ExAC gnomAD |
|
|
CA411850150 rs1383335878 |
44 | D>G | No |
ClinGen TOPMed |
|
|
rs1438017702 CA411850140 |
44 | D>N | No |
ClinGen gnomAD |
|
|
CA411850269 rs1372638302 |
45 | V>L | No |
ClinGen gnomAD |
|
|
rs143095808 CA10278369 RCV000886890 |
46 | V>I | No |
ClinGen ClinVar 1000Genomes ESP TOPMed dbSNP gnomAD |
|
| TCGA novel | 47 | V>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10278372 rs775258924 |
48 | Q>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1305896517 CA411850350 |
50 | V>A | No |
ClinGen TOPMed |
|
| TCGA novel | 51 | H>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 53 | D>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs955488570 CA324874858 |
53 | D>G | No |
ClinGen TOPMed gnomAD |
|
|
rs1028359521 CA324874856 |
53 | D>H | No |
ClinGen TOPMed |
|
| TCGA novel | 56 | G>E | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1603418713 CA411850459 |
56 | G>V | No |
ClinGen Ensembl |
|
|
rs760232267 CA10278373 |
57 | R>G | No |
ClinGen ExAC gnomAD |
|
|
CA411850519 rs1359011868 |
60 | D>N | No |
ClinGen TOPMed |
|
|
CA10278375 rs373727761 |
61 | D>G | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA gnomAD |
|
CA10278374 rs763765385 |
61 | D>N | No |
ClinGen ExAC gnomAD |
|
|
rs986851673 CA324874864 |
62 | I>V | No |
ClinGen gnomAD |
|
|
CA10278376 rs756767733 |
63 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs1469949998 CA411850630 |
64 | I>V | No |
ClinGen TOPMed gnomAD |
|
|
CA411850648 rs1379578956 |
65 | C>R | No |
ClinGen TOPMed |
|
|
CA411850653 rs1569025348 |
65 | C>Y | No |
ClinGen Ensembl |
|
|
rs750288005 CA10278378 |
67 | I>M | No |
ClinGen ExAC gnomAD |
|
|
rs146079721 CA10278377 |
67 | I>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1297594785 CA411850706 |
67 | I>V | No |
ClinGen TOPMed |
|
|
rs758249862 CA10278379 |
68 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA411850741 rs1176245235 |
69 | D>H | No |
ClinGen gnomAD |
|
|
rs779688779 CA10278380 |
72 | K>R | No |
ClinGen ExAC gnomAD |
|
|
rs1603418718 CA411850832 |
73 | A>T | No |
ClinGen Ensembl |
|
| TCGA novel | 75 | N>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10278382 rs200129176 |
76 | L>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs569129809 CA10278383 |
77 | I>T | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA411851475 rs1211488493 |
79 | V>G | No |
ClinGen gnomAD |
|
|
rs776459713 CA10278411 |
79 | V>I | No |
ClinGen ExAC gnomAD |
|
|
rs367937404 CA10278413 |
80 | M>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs761534315 CA10278412 |
80 | M>T | No |
ClinGen ExAC gnomAD |
|
|
CA324875978 rs1034386294 |
81 | R>Q | No |
ClinGen TOPMed |
|
|
CA10278414 rs372186642 |
81 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA411851512 rs1250637552 |
83 | S>C | No |
ClinGen TOPMed gnomAD |
|
|
rs762456444 CA10278415 |
84 | H>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA411851515 rs1420458227 |
84 | H>N | No |
ClinGen gnomAD |
|
|
rs762456444 CA411851520 |
84 | H>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs751476015 CA10278417 |
85 | E>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs766251685 CA10278416 |
85 | E>K | No |
ClinGen ExAC gnomAD |
|
|
rs140032620 CA10278418 |
87 | R>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA10278419 rs143559079 |
87 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs143559079 CA324875986 |
87 | R>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA411851594 rs1302289440 |
91 | L>H | No |
ClinGen gnomAD |
|
|
CA10278421 rs376401349 |
92 | R>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs147060461 CA10278422 |
92 | R>H | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA411851602 rs147060461 |
92 | R>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1377419148 CA411851611 |
93 | L>H | No |
ClinGen TOPMed |
|
|
rs1234666822 CA411851673 |
99 | V>M | No |
ClinGen gnomAD |
|
|
CA411851691 rs1282216096 |
100 | D>G | No |
ClinGen gnomAD |
|
| TCGA novel | 100 | D>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 100 | D>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10278424 rs757310529 |
101 | V>A | No |
ClinGen ExAC gnomAD |
|
|
CA10278425 rs779315929 |
103 | I>T | No |
ClinGen ExAC gnomAD |
|
|
CA411851747 rs1324761192 |
105 | T>A | No |
ClinGen TOPMed |
|
|
CA411851760 rs1481355154 |
106 | C>Y | No |
ClinGen gnomAD |
|
|
CA10278427 rs534986762 |
107 | Q>E | No |
ClinGen ExAC gnomAD |
|
|
rs1392190288 CA411851775 |
107 | Q>L | No |
ClinGen TOPMed |
|
|
rs1392190288 CA411851774 |
107 | Q>R | No |
ClinGen TOPMed |
|
|
rs1452509887 CA753456971 |
108 | G>K | No |
ClinGen TOPMed |
|
|
rs375589070 CA10278448 |
109 | D>H | No |
ClinGen ESP ExAC gnomAD |
|
|
CA10278449 VAR_057338 rs3761472 |
110 | D>G | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA411852017 rs3761472 |
110 | D>V | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs770409380 CA411852024 |
111 | A>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs770409380 CA10278451 |
111 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs201341859 CA10278453 |
114 | N>D | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA10278455 rs142640319 |
117 | D>E | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA411852081 rs1229777468 |
117 | D>N | No |
ClinGen gnomAD |
|
|
rs1010940178 CA324876734 |
117 | D>V | No |
ClinGen Ensembl |
|
| TCGA novel | 118 | V>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs556789427 CA10278456 |
118 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA411852107 rs1569028578 |
119 | T>I | No |
ClinGen Ensembl |
|
|
rs1216453827 CA411852125 |
120 | F>L | No |
ClinGen gnomAD |
|
|
rs1342357280 CA411852129 |
121 | E>Q | No |
ClinGen TOPMed |
|
|
rs377476119 CA324876742 |
122 | V>I | No |
ClinGen ESP |
|
|
CA411852150 rs1409295052 |
123 | T>I | No |
ClinGen TOPMed |
|
|
rs762081056 CA10278459 |
124 | E>G | No |
ClinGen ExAC gnomAD |
|
|
CA411852186 rs1192172744 |
126 | R>K | No |
ClinGen gnomAD |
|
|
CA324876749 rs765299671 |
127 | R>G | No |
ClinGen ExAC gnomAD |
|
|
CA10278462 rs150984629 |
129 | T>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs1405004983 CA411852268 |
130 | G>V | No |
ClinGen gnomAD |
|
|
CA10278464 rs371184429 |
132 | Y>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA411852314 rs371184429 |
132 | Y>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA10278466 rs781608078 |
134 | T>N | No |
ClinGen ExAC gnomAD |
|
|
rs142127145 CA10278467 |
135 | M>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1281936825 CA411852397 |
138 | N>K | No |
ClinGen gnomAD |
|
|
CA10278469 rs199632516 |
139 | N>S | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA411852461 rs1569028625 |
143 | M>T | No |
ClinGen Ensembl |
|
|
CA411852452 rs1224020203 |
143 | M>V | No |
ClinGen gnomAD |
|
|
rs1450184225 CA411852532 |
144 | V>L | No |
ClinGen gnomAD |
|
|
CA411852543 rs1441969759 |
145 | L>F | No |
ClinGen TOPMed gnomAD |
|
|
CA10278497 rs756388142 |
145 | L>R | No |
ClinGen ExAC gnomAD |
|
|
rs1240334920 CA411852550 |
146 | G>S | No |
ClinGen gnomAD |
|
|
CA10278498 rs778564857 |
147 | L>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1177721675 CA411852597 |
150 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
rs750044700 CA10278499 |
151 | N>S | No |
ClinGen ExAC TOPMed |
|
|
CA411852632 rs1344069154 |
154 | G>R | No |
ClinGen TOPMed |
|
|
rs760694382 CA324876928 |
155 | R>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs372431320 CA10278500 |
155 | R>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA411852691 rs1603419125 |
159 | V>G | No |
ClinGen Ensembl |
|
|
rs376336708 CA10278501 |
160 | T>N | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA411852743 rs1170799043 |
164 | S>Y | No |
ClinGen gnomAD |
|
|
CA10278503 rs768642813 |
165 | Y>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA411852750 rs768642813 |
165 | Y>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs746985408 CA10278502 |
165 | Y>H | No |
ClinGen ExAC gnomAD |
|
|
CA324876940 rs201147696 |
167 | T>I | No |
ClinGen Ensembl |
|
| TCGA novel | 169 | E>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA411852805 rs1332796193 |
170 | T>I | No |
ClinGen gnomAD |
|
|
CA10278504 rs147789611 |
171 | S>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA411852833 rs747996230 |
173 | G>D | No |
ClinGen ExAC gnomAD |
|
|
CA10278505 rs747996230 |
173 | G>V | No |
ClinGen ExAC gnomAD |
|
|
rs1279631581 CA411852840 |
174 | L>Q | No |
ClinGen gnomAD |
|
|
rs1380492770 CA411852862 |
176 | F>S | No |
ClinGen TOPMed |
|
|
rs773618986 CA10278507 |
177 | F>L | No |
ClinGen ExAC gnomAD |
|
|
CA10278508 rs763255508 |
179 | P>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA324876941 rs763255508 |
179 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs774496859 CA10278510 |
180 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM304550 CA10278509 rs771203161 |
180 | R>W | large_intestine [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
rs535356871 CA10278511 |
181 | P>S | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs535356871 CA10278512 |
181 | P>T | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA10278514 rs183923403 |
182 | G>R | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
rs764417280 CA10278516 |
184 | F>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10278517 rs578136170 |
185 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
CA411852995 rs1211528069 |
187 | N>S | No |
ClinGen gnomAD |
|
|
rs757207629 CA10278543 |
190 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs757207629 CA10278542 |
190 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10278544 rs777798922 |
191 | N>D | No |
ClinGen ExAC gnomAD |
|
|
rs1313546780 CA411853414 |
191 | N>T | No |
ClinGen TOPMed gnomAD |
|
|
rs1354211426 CA411853450 |
193 | Y>* | No |
ClinGen gnomAD |
|
|
CA10278547 rs180928342 |
193 | Y>H | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs374982740 CA10278548 |
194 | K>N | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs772249410 CA10278549 |
196 | T>I | No |
ClinGen ExAC gnomAD |
|
|
rs747021327 CA10278551 |
198 | Q>E | No |
ClinGen ExAC |
|
|
CA10278552 rs769163632 |
200 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs777074079 CA411853582 |
202 | S>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10278554 rs550259267 |
203 | S>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs113373406 CA10278558 |
205 | R>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs113373406 CA10278557 |
205 | R>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA10278556 rs113373406 |
205 | R>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA10278555 rs150292452 |
205 | R>W | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA10278560 rs200502238 |
207 | T>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA411853659 rs1453700073 |
208 | D>N | No |
ClinGen gnomAD |
|
|
rs1394488573 CA411853688 |
210 | G>A | No |
ClinGen gnomAD |
|
|
rs1284103045 CA411853696 |
211 | M>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1314699831 CA411853726 |
213 | A>T | No |
ClinGen gnomAD |
|
|
rs773639710 CA324877062 |
214 | E>D | No |
ClinGen Ensembl |
|
|
rs577506632 CA10278587 |
219 | I>M | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA10278586 rs193152135 |
219 | I>V | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs751747955 CA10278588 |
220 | W>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs751747955 CA324877631 |
220 | W>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs755098914 CA324877634 |
222 | T>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10278589 rs755098914 |
222 | T>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1351261822 CA411854203 |
223 | S>G | No |
ClinGen TOPMed gnomAD |
|
|
CA411854238 rs1201644170 |
225 | T>S | No |
ClinGen TOPMed |
|
|
rs748162093 CA324877638 |
226 | V>F | No |
ClinGen ExAC gnomAD |
|
|
CA10278591 rs748162093 |
226 | V>I | No |
ClinGen ExAC gnomAD |
|
|
CA411854262 rs1569030183 |
227 | K>N | No |
ClinGen Ensembl |
|
|
rs35189432 CA10278592 |
227 | K>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA10278594 rs749649786 |
230 | G>C | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 230 | G>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10278596 rs775334315 |
231 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM1566424 rs143794573 CA10278598 |
233 | R>* | Variant assessed as Somatic; 0.0001386 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs143794573 CA411854308 |
233 | R>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1603419409 CA411854318 |
234 | E>D | No |
ClinGen Ensembl |
|
|
rs752221535 CA324877648 |
235 | L>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10278600 rs761326583 |
235 | L>Q | No |
ClinGen ExAC gnomAD |
|
|
rs761326583 CA411854321 |
235 | L>R | No |
ClinGen ExAC gnomAD |
|
|
CA10278599 rs752221535 |
235 | L>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs916128511 CA324877651 |
238 | L>F | No |
ClinGen gnomAD |
|
|
rs916128511 CA411854336 |
238 | L>V | No |
ClinGen gnomAD |
|
|
rs765107676 CA10278601 |
239 | S>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs202225451 CA10278603 |
241 | T>M | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs751847892 CA10278605 |
242 | A>T | No |
ClinGen ExAC gnomAD |
|
|
CA10278606 rs755197408 |
242 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA411854377 rs1603419413 |
245 | A>P | No |
ClinGen Ensembl |
|
|
CA10278609 rs756181628 |
247 | R>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10278611 rs749785044 |
247 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA10278612 rs757758267 |
248 | K>E | No |
ClinGen ExAC |
|
|
rs1292436268 CA411854409 |
250 | S>N | No |
ClinGen gnomAD |
|
| TCGA novel | 250 | S>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA324877665 rs971622317 |
251 | G>E | No |
ClinGen Ensembl |
|
|
CA10278614 rs746163894 |
251 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1466982317 CA411854424 |
252 | H>P | No |
ClinGen TOPMed |
|
|
rs1172693562 CA411854421 |
252 | H>Y | No |
ClinGen TOPMed |
|
|
CA10278615 rs371015652 |
253 | S>* | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA324877671 rs908556538 |
258 | L>F | No |
ClinGen Ensembl |
|
|
rs769314961 CA10278618 |
259 | S>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs769314961 CA10278619 |
259 | S>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1381976473 CA411854528 |
261 | A>V | No |
ClinGen gnomAD |
|
|
rs138855728 CA10278636 |
262 | M>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA324877800 rs111832403 |
264 | I>V | No |
ClinGen Ensembl |
|
|
rs748738734 CA10278639 |
265 | D>A | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 265 | D>E | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10278638 rs772784326 |
265 | D>N | No |
ClinGen ExAC gnomAD |
|
|
rs1331637489 CA411854578 |
266 | S>C | No |
ClinGen gnomAD |
|
|
CA10278641 rs78038328 |
267 | R>Q | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs770878935 CA10278640 |
267 | R>W | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 269 | S>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA411854620 rs1310410925 |
271 | I>V | No |
ClinGen gnomAD |
|
|
CA10278642 rs759370039 |
278 | L>* | No |
ClinGen ExAC gnomAD |
|
|
rs767280050 CA411854699 |
279 | L>V | No |
ClinGen ExAC gnomAD |
|
|
CA10278644 rs775636410 |
282 | N>S | No |
ClinGen ExAC gnomAD |
|
|
CA411854739 rs1220963357 |
283 | Q>* | No |
ClinGen gnomAD |
|
|
CA411854742 rs1456990760 |
283 | Q>R | No |
ClinGen Ensembl |
|
|
CA411854935 rs778873552 |
284 | E>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA411854932 rs778873552 |
284 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10278658 rs778873552 |
284 | E>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1461193272 CA411854944 |
285 | L>M | No |
ClinGen gnomAD |
|
|
CA10278659 rs745794022 |
286 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA10278661 rs200554343 |
289 | T>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10278664 rs768942973 |
291 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs79109650 CA10278665 |
292 | D>G | No |
ClinGen ExAC gnomAD |
|
|
CA10278666 rs762022694 |
294 | S>G | No |
ClinGen ExAC |
|
|
CA411855045 rs1227018135 |
294 | S>N | No |
ClinGen gnomAD |
|
|
rs1265787207 CA411855069 |
296 | I>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1265787207 CA411855070 |
296 | I>V | No |
ClinGen TOPMed gnomAD |
|
|
rs1321116921 CA411855090 |
297 | K>N | No |
ClinGen TOPMed |
|
| TCGA novel | 298 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1358274022 CA411855092 |
298 | E>Q | No |
ClinGen gnomAD |
|
|
CA411855113 rs1220151356 |
299 | D>G | No |
ClinGen gnomAD |
|
|
CA10278668 rs372628743 |
304 | L>F | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1195154078 CA411855201 |
306 | K>R | No |
ClinGen gnomAD |
|
|
rs751975574 CA10278671 |
307 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
rs755260870 CA10278672 |
307 | Q>H | No |
ClinGen ExAC gnomAD |
|
|
CA411855228 rs1427025149 |
309 | I>T | No |
ClinGen gnomAD |
|
|
rs982873024 CA324877958 |
310 | F>C | No |
ClinGen TOPMed gnomAD |
|
|
rs777522514 CA10278673 |
312 | S>L | No |
ClinGen ExAC gnomAD |
|
|
CA411855339 rs1204950889 |
314 | F>V | No |
ClinGen TOPMed |
|
|
CA324878699 rs936071282 |
316 | A>V | No |
ClinGen TOPMed gnomAD |
|
|
CA324878703 rs780934766 |
318 | F>L | No |
ClinGen Ensembl |
|
|
rs372891737 CA324878707 |
321 | G>R | No |
ClinGen ESP TOPMed gnomAD |
|
|
CA324878709 rs769503551 |
322 | M>T | No |
ClinGen Ensembl |
|
|
CA411855406 rs1233273196 |
324 | V>I | No |
ClinGen TOPMed gnomAD |
|
|
CA411855415 rs1257272353 |
325 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
CA411855414 rs1257272353 |
325 | P>R | No |
ClinGen TOPMed gnomAD |
|
|
CA10278694 rs544465311 |
326 | I>T | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1242902945 CA411855442 |
328 | D>N | No |
ClinGen TOPMed gnomAD |
|
|
rs575124332 CA10278696 |
328 | D>V | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs749953055 CA10278697 |
329 | K>E | No |
ClinGen ExAC |
|
|
rs757803599 CA10278698 |
329 | K>R | No |
ClinGen ExAC gnomAD |
|
|
CA10278699 rs375707409 |
330 | P>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs369058216 COSM1731071 CA10278701 |
332 | S>G | liver [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD |
|
CA324878718 rs895844545 |
333 | I>T | No |
ClinGen TOPMed |
|
|
CA10278702 rs781129512 |
334 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA324878722 rs1013404863 |
335 | D>G | No |
ClinGen TOPMed |
|
|
rs765791684 CA10278717 |
337 | F>C | No |
ClinGen ExAC gnomAD |
|
|
rs781217777 CA10278720 |
340 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs747987580 CA10278721 |
341 | G>* | No |
ClinGen ExAC gnomAD |
|
|
CA411855769 rs1317580367 |
344 | S>G | No |
ClinGen TOPMed |
|
|
CA411855771 rs1294508060 |
344 | S>N | No |
ClinGen gnomAD |
|
|
CA411855777 rs8418 |
345 | I>F | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs8418 VAR_013768 CA10278724 |
345 | I>V | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA10278725 rs771112589 |
346 | R>C | No |
ClinGen ExAC gnomAD |
|
|
rs995506644 CA324879176 |
346 | R>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs745907041 CA10278727 |
347 | G>R | No |
ClinGen ExAC gnomAD |
|
|
rs772594585 CA10278728 |
349 | S>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs775931631 CA10278729 |
349 | S>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA411855811 rs1363586530 |
350 | M>I | No |
ClinGen gnomAD |
|
|
CA411855809 rs1165253169 |
350 | M>T | No |
ClinGen gnomAD |
|
|
rs959797810 CA324879182 |
353 | I>V | No |
ClinGen gnomAD |
|
|
rs761064487 CA10278730 |
354 | G>R | No |
ClinGen ExAC gnomAD |
|
|
rs1428203434 CA411855845 |
355 | P>R | No |
ClinGen gnomAD |
|
|
rs749568021 CA10278731 |
356 | Q>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs772973443 CA10278732 |
357 | S>N | No |
ClinGen ExAC gnomAD |
|
|
CA10278733 rs373830089 |
358 | E>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA10278767 rs747023308 |
359 | G>E | No |
ClinGen ExAC gnomAD |
|
|
COSM247175 CA411855916 rs1173734821 |
363 | G>V | prostate [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
rs755487664 CA411855936 |
366 | A>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1301880301 CA411855932 |
366 | A>T | No |
ClinGen TOPMed |
|
|
CA10278768 rs755487664 |
366 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1329939846 CA411855959 |
369 | A>V | No |
ClinGen gnomAD |
|
|
rs770172829 CA10278771 |
370 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM3740459 CA10278773 rs745513145 |
371 | G>S | liver [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
CA411855975 rs1262917260 |
373 | H>N | No |
ClinGen TOPMed |
|
|
rs1037082670 CA324880275 |
375 | Y>C | No |
ClinGen Ensembl |
|
|
CA324880278 rs897242202 |
376 | T>I | No |
ClinGen Ensembl |
|
|
rs1181488940 CA411855996 |
376 | T>P | No |
ClinGen TOPMed |
|
|
CA10278777 rs200604349 |
377 | P>A | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs200604349 CA411856002 |
377 | P>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1252362347 CA411856015 |
379 | P>S | No |
ClinGen gnomAD |
|
|
CA10278778 rs776596324 |
380 | F>C | No |
ClinGen ExAC gnomAD |
|
|
CA411856027 rs765065046 |
381 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10278780 rs765065046 |
381 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10278779 rs544173089 |
381 | R>W | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1481172154 CA411856038 |
383 | G>D | No |
ClinGen gnomAD |
|
|
CA411856044 rs1196635235 |
384 | Q>R | No |
ClinGen gnomAD |
|
|
rs1235527275 CA411856093 |
391 | F>S | No |
ClinGen gnomAD |
|
|
CA411856098 rs1462151767 |
392 | R>* | No |
ClinGen gnomAD |
|
|
CA10278782 rs750708573 |
392 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10278781 rs750708573 |
392 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA411856101 rs1399023431 |
393 | T>A | No |
ClinGen gnomAD |
|
|
CA10278784 rs766529644 |
394 | H>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 394 | H>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10278786 rs755045455 |
395 | F>S | No |
ClinGen ExAC gnomAD |
|
|
rs751660124 CA10278785 |
395 | F>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10278788 rs574363713 |
399 | A>T | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
| TCGA novel | 400 | G>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1281425591 CA411856156 |
401 | N>S | No |
ClinGen gnomAD |
|
|
rs1345157019 CA411856175 |
403 | C>Y | No |
ClinGen gnomAD |
|
|
CA10278791 rs749603545 |
406 | N>D | No |
ClinGen ExAC gnomAD |
|
|
rs1195010191 CA411856216 |
406 | N>K | No |
ClinGen gnomAD |
|
|
rs1017479356 CA324880296 |
406 | N>S | No |
ClinGen gnomAD |
|
|
rs1020371092 CA324880298 COSM126011 |
407 | Y>C | upper_aerodigestive_tract [Cosmic] | No |
ClinGen cosmic curated TOPMed |
|
rs771869848 CA10278792 |
407 | Y>D | No |
ClinGen ExAC gnomAD |
|
|
CA411856361 rs769794460 |
409 | E>* | No |
ClinGen ExAC gnomAD |
|
|
CA10278816 rs769794460 |
409 | E>K | No |
ClinGen ExAC gnomAD |
|
|
CA411856370 rs1368399386 |
410 | G>D | No |
ClinGen gnomAD |
|
|
CA411856367 COSM1224639 rs1162154121 |
410 | G>S | large_intestine [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
CA411856372 rs1368399386 |
410 | G>V | No |
ClinGen gnomAD |
|
|
CA411856383 rs1454427705 |
412 | K>R | No |
ClinGen TOPMed gnomAD |
|
|
CA411856388 rs1197536938 |
413 | A>T | No |
ClinGen TOPMed |
|
|
rs376687615 CA10278818 |
414 | H>D | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 414 | H>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs376687615 CA10278817 COSM1196524 |
414 | H>Y | lung [Cosmic] | No |
ClinGen cosmic curated ESP ExAC TOPMed gnomAD |
|
CA10278819 rs201717661 |
416 | R>C | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1434597186 CA411856418 |
416 | R>H | No |
ClinGen gnomAD |
|
|
CA10278821 rs759807839 |
418 | L>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA411856443 rs1314378187 |
419 | A>T | No |
ClinGen gnomAD |
|
|
CA411856451 rs1317430174 |
420 | E>K | No |
ClinGen gnomAD |
|
|
CA920378907 rs1569036298 |
421 | C>* | No |
ClinGen Ensembl |
|
|
CA10278823 rs752841571 |
421 | C>G | No |
ClinGen ExAC gnomAD |
|
|
rs1349539399 CA411856467 |
421 | C>Y | No |
ClinGen gnomAD |
|
|
CA10278824 COSM131296 rs139551220 |
423 | R>C | liver [Cosmic] | No |
ClinGen cosmic curated ESP ExAC TOPMed gnomAD |
|
rs1244139143 CA411856488 |
423 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA10278827 rs757758374 |
424 | W>C | No |
ClinGen ExAC gnomAD |
|
|
rs201556963 CA10278826 |
424 | W>G | No |
ClinGen ExAC gnomAD |
|
|
CA324880586 rs201556963 |
424 | W>R | No |
ClinGen ExAC gnomAD |
|
|
rs150932882 CA10278829 |
426 | Y>C | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
| rs1460012287 | 428 | A>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA411856535 rs1456928361 |
428 | A>T | No |
ClinGen gnomAD |
|
|
rs747726024 CA10278832 |
429 | G>R | No |
ClinGen ExAC gnomAD |
|
|
rs769263451 CA10278833 |
431 | V>F | No |
ClinGen ExAC gnomAD |
|
|
CA10278834 rs777745951 |
432 | L>I | No |
ClinGen ExAC gnomAD |
|
|
CA411856603 rs1163863724 |
435 | G>D | No |
ClinGen TOPMed |
|
|
rs1374017249 CA411856614 |
436 | N>S | No |
ClinGen gnomAD |
|
|
CA324880602 rs1057257905 |
438 | A>T | No |
ClinGen TOPMed gnomAD |
|
|
rs770786826 CA411856641 |
439 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs774207483 CA411856645 |
439 | R>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs774207483 CA10278837 |
439 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10278836 rs770786826 |
439 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10278839 rs772367701 |
443 | N>S | No |
ClinGen ExAC |
|
|
COSM3062540 rs760853554 CA10278841 |
446 | V>I | kidney [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
rs564746456 CA10278842 |
448 | M>V | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs754465662 CA10278843 |
453 | G>S | No |
ClinGen ExAC gnomAD |
|
|
CA411856831 rs1248515000 |
454 | D>E | No |
ClinGen gnomAD |
|
|
CA411843003 rs1289155925 |
455 | R>S | No |
ClinGen gnomAD |
|
|
rs543581425 CA324876889 |
456 | I>V | No |
ClinGen 1000Genomes |
|
|
rs1020031347 CA324876891 |
457 | C>R | No |
ClinGen TOPMed gnomAD |
|
|
rs1020031347 CA411843010 |
457 | C>S | No |
ClinGen TOPMed gnomAD |
|
|
rs1216739066 CA411843013 |
457 | C>Y | No |
ClinGen gnomAD |
|
|
CA324876892 rs146627813 |
459 | G>D | No |
ClinGen ESP gnomAD |
|
| TCGA novel | 460 | V>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10278872 rs755775256 |
462 | F>C | No |
ClinGen ExAC |
|
|
rs763685097 CA411843060 |
464 | A>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs763685097 CA10278873 |
464 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10278874 rs753374189 |
465 | G>V | No |
ClinGen ExAC gnomAD |
|
|
rs756726611 CA10278875 |
466 | I>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs930159075 CA324876906 |
466 | I>M | No |
ClinGen Ensembl |
|
|
rs778954287 CA411843072 |
467 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs778954287 CA10278876 |
467 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1240523666 CA411843080 |
468 | F>V | No |
ClinGen gnomAD |
|
|
rs758284648 CA10278878 |
470 | L>Y | No |
ClinGen ExAC gnomAD |
No associated diseases with Q9Y512
No regional properties for Q9Y512
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9Y512 | |||
6 GO annotations of cellular component
| Name | Definition |
|---|---|
| extracellular exosome | A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| MIB complex | A mitochondrial intermembrane space bridging complex consisting of components of the MICOS complex in the inner mitochondrial membrane, the SAM complex in the outer membrane, a conserved DNAJ protein (human DNAJC11) and Metaxin 1. |
| mitochondrial outer membrane | The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
| SAM complex | A large complex of the mitochondrial outer membrane that mediates sorting of some imported proteins to the outer membrane and their assembly in the membrane; functions after import of incoming proteins by the mitochondrial outer membrane translocase complex. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| cristae formation | The assembly of cristae, the inwards folds of the inner mitochondrial membrane. |
| inner mitochondrial membrane organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial inner membrane. |
| mitochondrial respiratory chain complex assembly | The aggregation, arrangement and bonding together of a set of components to form a mitochondrial respiratory chain complex. |
| protein insertion into mitochondrial outer membrane | The process comprising the insertion of proteins from outside the organelle into the mitochondrial outer membrane, mediated by large outer membrane translocase complexes. |
7 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q2HJ55 | SAMM50 | Sorting and assembly machinery component 50 homolog | Bos taurus (Bovine) | PR |
| Q9V784 | CG7639 | SAM50-like protein CG7639 | Drosophila melanogaster (Fruit fly) | PR |
| Q8BGH2 | Samm50 | Sorting and assembly machinery component 50 homolog | Mus musculus (Mouse) | PR |
| Q6AXV4 | Samm50 | Sorting and assembly machinery component 50 homolog | Rattus norvegicus (Rat) | PR |
| Q6P806 | samm50 | Sorting and assembly machinery component 50 homolog | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| Q5U3I0 | samm50b | Sorting and assembly machinery component 50 homolog B | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q803G5 | samm50a | Sorting and assembly machinery component 50 homolog A | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGTVHARSLE | PLPSSGPDFG | GLGEEAEFVE | VEPEAKQEIL | ENKDVVVQHV | HFDGLGRTKD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DIIICEIGDV | FKAKNLIEVM | RKSHEAREKL | LRLGIFRQVD | VLIDTCQGDD | ALPNGLDVTF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EVTELRRLTG | SYNTMVGNNE | GSMVLGLKLP | NLLGRAEKVT | FQFSYGTKET | SYGLSFFKPR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PGNFERNFSV | NLYKVTGQFP | WSSLRETDRG | MSAEYSFPIW | KTSHTVKWEG | VWRELGCLSR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TASFAVRKES | GHSLKSSLSH | AMVIDSRNSS | ILPRRGALLK | VNQELAGYTG | GDVSFIKEDF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ELQLNKQLIF | DSVFSASFWG | GMLVPIGDKP | SSIADRFYLG | GPTSIRGFSM | HSIGPQSEGD |
| 370 | 380 | 390 | 400 | 410 | 420 |
| YLGGEAYWAG | GLHLYTPLPF | RPGQGGFGEL | FRTHFFLNAG | NLCNLNYGEG | PKAHIRKLAE |
| 430 | 440 | 450 | 460 | ||
| CIRWSYGAGI | VLRLGNIARL | ELNYCVPMGV | QTGDRICDGV | QFGAGIRFL |