Q803G5
Gene name |
samm50a (samm50, zgc:55803) |
Protein name |
Sorting and assembly machinery component 50 homolog A |
Names |
|
Species |
Danio rerio (Zebrafish) (Brachydanio rerio) |
KEGG Pathway |
dre:393111 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q803G5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q803G5-F1 | Predicted | AlphaFoldDB |
No variants for Q803G5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q803G5 | |||||
No associated diseases with Q803G5
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| SAM complex | A large complex of the mitochondrial outer membrane that mediates sorting of some imported proteins to the outer membrane and their assembly in the membrane; functions after import of incoming proteins by the mitochondrial outer membrane translocase complex. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| cristae formation | The assembly of cristae, the inwards folds of the inner mitochondrial membrane. |
| liver development | The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes. |
| mitochondrial respiratory chain complex assembly | The aggregation, arrangement and bonding together of a set of components to form a mitochondrial respiratory chain complex. |
| protein insertion into mitochondrial outer membrane | The process comprising the insertion of proteins from outside the organelle into the mitochondrial outer membrane, mediated by large outer membrane translocase complexes. |
7 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q2HJ55 | SAMM50 | Sorting and assembly machinery component 50 homolog | Bos taurus (Bovine) | PR |
| Q9V784 | CG7639 | SAM50-like protein CG7639 | Drosophila melanogaster (Fruit fly) | PR |
| Q9Y512 | SAMM50 | Sorting and assembly machinery component 50 homolog | Homo sapiens (Human) | PR |
| Q8BGH2 | Samm50 | Sorting and assembly machinery component 50 homolog | Mus musculus (Mouse) | PR |
| Q6AXV4 | Samm50 | Sorting and assembly machinery component 50 homolog | Rattus norvegicus (Rat) | PR |
| Q6P806 | samm50 | Sorting and assembly machinery component 50 homolog | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| Q5U3I0 | samm50b | Sorting and assembly machinery component 50 homolog B | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGTVHARSLD | PLPMQGPELG | VQADDMDLGE | PEREEKQEVL | ENKDVVVQHV | HIDGLGRTKE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DILTYEIADV | FHAKNLIDVM | KKSHEARQKL | LRLGIFRHVE | VVIDTAEGAD | ALPNGLDVTF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EVRELRRMTG | SYNTMVGNNE | GSMVLGIKLP | NVLGRAEKLT | FQFSYGTKET | SYGLSFFKPQ |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PGHFERNFSL | NLYKVTGQFP | WSSLRETDRG | VSAEISFPIW | RTSHTLKWEG | VWRELGCLAR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TASFAVREES | GHSLKSSLAH | AMVIDTRNST | ILPRKGALLK | INQELAGYTG | GDVSFLKEDF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EIQLNKTLFW | DSVLSTSLWG | GMLLPLGEKA | SSIADRFYLG | GPTSVRGFSM | YSIGPQSEGD |
| 370 | 380 | 390 | 400 | 410 | 420 |
| YLGGEAYWAG | GVHLYTPLPF | RPGRGGFGDL | FRTHFFLNAG | NLCNLNYGEG | PRAHLSKLAE |
| 430 | 440 | 450 | 460 | ||
| CIRWSYGAGI | VLRLGNIARL | ELNYCIPMGV | QSGDRICDGV | QFGAGIRFL |