Q9W1V1

PR
Gene name
Art7 (CG9882)
Protein name
Protein arginine N-methyltransferase 7
Names
Dart7
Species
Drosophila melanogaster (Fruit fly)
KEGG Pathway
dme:Dmel_CG9882
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-48 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9W1V1

Entry ID Method Resolution Chain Position Source
AF-Q9W1V1-F1 Predicted AlphaFoldDB

No variants for Q9W1V1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9W1V1

No associated diseases with Q9W1V1

2 regional properties for Q9W1V1

Type Name Position InterPro Accession
domain F-box domain 15 - 65 IPR001810
domain FBD domain 368 - 443 IPR006566

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
protein-arginine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + (protein)-arginine = S-adenosyl-L-homocysteine + (protein)-N-methyl-arginine.
protein-arginine omega-N monomethyltransferase activity Catalysis of the addition of a methyl group to either of the unmethylated terminal nitrogen atoms (also called omega nitrogen) in peptidyl-arginine to form an omega-N-G-monomethylated arginine residue. The reaction is S-adenosyl-L-methionine
protein-arginine omega-N symmetric methyltransferase activity +Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the terminal nitrogen (omega nitrogen) residue that is not already methylated, resulting in symmetrical peptidyl-N(omega),N'(omega)-dimethyled arginine residues.

2 GO annotations of biological process

Name Definition
peptidyl-arginine methylation The addition of a methyl group to an arginine residue in a protein.
peptidyl-arginine methylation, to asymmetrical-dimethyl arginine The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N(omega)-dimethyl-L-arginine.

8 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
A6QQV6 PRMT7 Protein arginine N-methyltransferase 7 Bos taurus (Bovine) PR
Q5ZIB9 PRMT7 Protein arginine N-methyltransferase 7 Gallus gallus (Chicken) PR
Q6P2P2 PRMT9 Protein arginine N-methyltransferase 9 Homo sapiens (Human) PR
Q9NVM4 PRMT7 Protein arginine N-methyltransferase 7 Homo sapiens (Human) PR
Q3U3W5 Prmt9 Protein arginine N-methyltransferase 9 Mus musculus (Mouse) PR
Q922X9 Prmt7 Protein arginine N-methyltransferase 7 Mus musculus (Mouse) PR
Q5U4E8 Prmt7 Protein arginine N-methyltransferase 7 Rattus norvegicus (Rat) PR
A2AV36 prmt7 Protein arginine N-methyltransferase 7 Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MSCFSHVMNP ITGQNSWQER GDDYDYHLEV ANAGFGDMLH DWERNQKYFA ALRKTIAGMR
70 80 90 100 110 120
EAGREVHVLD IGTGTGILSM MALAAGADSV TACEAFLPMA NCAEKILAAN GAGDKVRLIR
130 140 150 160 170 180
KRSTEIQVGE DMPRKANLLV AELLDTELIG EGAIGIYNHA HAELLTEDAL CIPARARCYA
190 200 210 220 230 240
QVAQSPLAAQ WNSLKTIANL DGEPLLHPPE QLKSCQGEAA LHDVQLSQLP SSAFRPLTDP
250 260 270 280 290 300
VEIFQFDFQR KQEREKQRSQ LLKLQSKQPG AAELVFYWWD IQLDDDGEIL LSCAPYWAHP
310 320 330 340 350 360
QLKELAAEKA KDHPLPNVVP WRDHWMQAIY YIPKPLQLLE AGKSFHLSCH HDEYSLWFDA
370 380 390 400 410 420
REEAPTKSVR RHTCTCDLHM TYSRSRIGQL NQSPRNKRYL RYLEESIEAE KSNVLVLGNG
430 440 450 460 470 480
CLLGLASSAL GAASVLLHEP HRFSRRLIES IVKHNQLKNV QFLDKVEELE DSRLAALTHI
490 500 510 520 530 540
FAEPYFLNAI LPWDNFYFGT LLTKIKDRLP EGVKISPCSA RIYALPVEFL DLHKIRAPVG
550 560 570 580 590 600
SCEGFDLRLF DEMVERSAEQ AVSLVEAQPL WEYPCRALSE PQEVLSVDFS NFGQEHSLKG
610 620 630 640 650 660
SIELKHPRIC NGVALWVDWQ LVEDNSPRSI VSSGPSEPVV PGEFVKWDMF VRQGVHFPRR
670 680
PKEAITHLEW STVFKPLLGE LTFSFGQKKL